Mus musculus

0 known processes

Rassf1

Ras association (RalGDS/AF-6) domain family member 1

(Aliases: AU044980,NORE2A,Rassf1A,Rassf1C,Rassf1B,REH3P21,123F2,AA536941,RDA32)

Rassf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transferase activity GO:0051338 263 0.184
positive regulation of apoptotic process GO:0043065 217 0.175
dna metabolic process GO:0006259 303 0.170
endothelial cell apoptotic process GO:0072577 9 0.147
positive regulation of apoptotic signaling pathway GO:2001235 95 0.135
regulation of protein kinase activity GO:0045859 232 0.133
mitotic cell cycle process GO:1903047 159 0.129
cellular response to dna damage stimulus GO:0006974 207 0.127
Human
positive regulation of protein phosphorylation GO:0001934 242 0.113
mitotic cell cycle GO:0000278 195 0.108
cell type specific apoptotic process GO:0097285 268 0.107
protein modification by small protein conjugation GO:0032446 187 0.099
Human Mouse
macromolecule catabolic process GO:0009057 281 0.097
neuron death GO:0070997 154 0.095
modification dependent macromolecule catabolic process GO:0043632 133 0.094
regulation of neuron death GO:1901214 134 0.091
positive regulation of transferase activity GO:0051347 167 0.090
regulation of apoptotic signaling pathway GO:2001233 197 0.090
positive regulation of kinase activity GO:0033674 155 0.085
mitotic cytokinesis GO:0000281 4 0.078
modification dependent protein catabolic process GO:0019941 133 0.078
regulation of cellular catabolic process GO:0031329 242 0.077
negative regulation of molecular function GO:0044092 258 0.077
positive regulation of cell death GO:0010942 224 0.076
response to growth factor GO:0070848 198 0.073
regulation of defense response GO:0031347 233 0.071
cellular amino acid metabolic process GO:0006520 103 0.071
signal transduction by p53 class mediator GO:0072331 51 0.067
ubiquitin dependent protein catabolic process GO:0006511 129 0.064
negative regulation of phosphate metabolic process GO:0045936 184 0.063
regulation of protein maturation GO:1903317 96 0.061
proteasomal protein catabolic process GO:0010498 98 0.060
regulation of cellular response to stress GO:0080135 159 0.059
negative regulation of phosphorylation GO:0042326 166 0.059
negative regulation of phosphorus metabolic process GO:0010563 184 0.057
cellular amine metabolic process GO:0044106 44 0.057
mapk cascade GO:0000165 281 0.054
leukocyte differentiation GO:0002521 342 0.053
Mouse
skeletal muscle organ development GO:0060538 163 0.051
ion transmembrane transport GO:0034220 361 0.051
cellular response to growth factor stimulus GO:0071363 197 0.051
positive regulation of protein modification process GO:0031401 299 0.050
Human Mouse
positive regulation of programmed cell death GO:0043068 218 0.050
protein localization to organelle GO:0033365 185 0.048
Mouse
protein catabolic process GO:0030163 221 0.046
chromatin modification GO:0016568 187 0.046
negative regulation of intracellular signal transduction GO:1902532 167 0.045
Mouse
protein processing GO:0016485 163 0.044
negative regulation of transferase activity GO:0051348 85 0.044
apoptotic signaling pathway GO:0097190 306 0.043
transmembrane transport GO:0055085 412 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.042
protein ubiquitination GO:0016567 171 0.040
Human Mouse
t cell activation GO:0042110 289 0.040
negative regulation of protein phosphorylation GO:0001933 126 0.039
intrinsic apoptotic signaling pathway GO:0097193 132 0.039
cell division GO:0051301 120 0.038
amine metabolic process GO:0009308 45 0.038
negative regulation of cellular amine metabolic process GO:0033239 1 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
cellular protein catabolic process GO:0044257 155 0.036
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
negative regulation of kinase activity GO:0033673 81 0.036
striated muscle tissue development GO:0014706 293 0.036
regulation of kinase activity GO:0043549 249 0.036
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.034
muscle tissue development GO:0060537 308 0.034
protein maturation GO:0051604 176 0.034
negative regulation of response to wounding GO:1903035 77 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
inflammatory response GO:0006954 244 0.032
cation transport GO:0006812 399 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
response to transforming growth factor beta GO:0071559 88 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
negative regulation of lymphocyte activation GO:0051250 91 0.031
negative regulation of protein maturation GO:1903318 79 0.031
negative regulation of proteolysis GO:0045861 74 0.031
adult behavior GO:0030534 135 0.031
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.030
negative regulation of cell cycle arrest GO:0071157 1 0.030
Human
response to reactive oxygen species GO:0000302 56 0.030
purine nucleotide metabolic process GO:0006163 302 0.029
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.029
negative regulation of protein modification process GO:0031400 163 0.028
muscle system process GO:0003012 141 0.028
regionalization GO:0003002 337 0.028
anion transmembrane transport GO:0098656 71 0.028
lens morphogenesis in camera type eye GO:0002089 24 0.027
cell adhesion GO:0007155 329 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.027
stem cell differentiation GO:0048863 268 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
Human
regulation of mapk cascade GO:0043408 248 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
Mouse
neuron apoptotic process GO:0051402 142 0.026
negative regulation of cell activation GO:0050866 111 0.026
aromatic compound catabolic process GO:0019439 286 0.026
cell cycle g1 s phase transition GO:0044843 57 0.026
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
negative regulation of immune system process GO:0002683 209 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
regulation of protein ubiquitination GO:0031396 52 0.025
Human Mouse
regulation of response to dna damage stimulus GO:2001020 34 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of protein stability GO:0031647 52 0.025
Human
homeostasis of number of cells GO:0048872 210 0.024
Mouse
striated muscle cell development GO:0055002 125 0.024
b cell activation GO:0042113 161 0.024
regulation of inflammatory response GO:0050727 147 0.024
intracellular receptor signaling pathway GO:0030522 74 0.024
synaptic transmission GO:0007268 329 0.024
g1 s transition of mitotic cell cycle GO:0000082 57 0.023
cellular response to biotic stimulus GO:0071216 92 0.023
camera type eye development GO:0043010 266 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.022
Human Mouse
reactive oxygen species metabolic process GO:0072593 84 0.022
traversing start control point of mitotic cell cycle GO:0007089 2 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
jnk cascade GO:0007254 72 0.022
fat cell differentiation GO:0045444 160 0.022
regulation of mitotic cell cycle GO:0007346 126 0.021
chromatin assembly GO:0031497 13 0.021
angiogenesis GO:0001525 201 0.021
regulation of cell migration GO:0030334 219 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
forebrain development GO:0030900 302 0.020
carboxylic acid transport GO:0046942 100 0.020
anion transport GO:0006820 177 0.020
regulation of protein catabolic process GO:0042176 108 0.020
gland development GO:0048732 330 0.020
myeloid leukocyte activation GO:0002274 83 0.020
regulation of protein processing GO:0070613 96 0.020
cytokine production GO:0001816 319 0.020
regulation of cell cycle g1 s phase transition GO:1902806 35 0.020
extracellular matrix organization GO:0030198 147 0.020
circulatory system process GO:0003013 197 0.020
methylation GO:0032259 134 0.019
dendrite development GO:0016358 115 0.019
protein localization to nucleus GO:0034504 121 0.019
Mouse
mitotic cell cycle checkpoint GO:0007093 31 0.019
regulation of cytokine production GO:0001817 266 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
peptidyl amino acid modification GO:0018193 336 0.019
response to drug GO:0042493 75 0.019
response to extracellular stimulus GO:0009991 127 0.019
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.019
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
skeletal system development GO:0001501 356 0.018
Mouse
negative regulation of protein catabolic process GO:0042177 36 0.018
response to light stimulus GO:0009416 135 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
response to lipopolysaccharide GO:0032496 128 0.018
positive regulation of chromatin modification GO:1903310 28 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
t cell differentiation in thymus GO:0033077 77 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
cell activation involved in immune response GO:0002263 126 0.018
response to oxidative stress GO:0006979 123 0.018
organic anion transport GO:0015711 137 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
fertilization GO:0009566 127 0.017
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.017
regulation of cell cycle GO:0051726 281 0.017
Human
regulation of fat cell differentiation GO:0045598 81 0.017
positive regulation of neuron death GO:1901216 28 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
regulation of cell activation GO:0050865 289 0.017
sensory organ morphogenesis GO:0090596 242 0.017
retina development in camera type eye GO:0060041 119 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
Human
response to radiation GO:0009314 165 0.016
muscle contraction GO:0006936 101 0.016
response to acid chemical GO:0001101 111 0.016
purine containing compound metabolic process GO:0072521 311 0.016
cellular ketone metabolic process GO:0042180 84 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
nuclear division GO:0000280 158 0.016
peptidyl lysine modification GO:0018205 77 0.016
lymphocyte differentiation GO:0030098 242 0.016
leukocyte proliferation GO:0070661 172 0.016
negative regulation of cell cycle GO:0045786 123 0.016
Human
nucleotide metabolic process GO:0009117 332 0.016
response to nutrient levels GO:0031667 109 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
Mouse
cation transmembrane transport GO:0098655 266 0.016
skeletal muscle cell differentiation GO:0035914 66 0.015
negative regulation of cellular catabolic process GO:0031330 47 0.015
mrna metabolic process GO:0016071 84 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
lymphocyte proliferation GO:0046651 164 0.015
peptidyl serine modification GO:0018209 83 0.015
regulation of stress activated mapk cascade GO:0032872 69 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
negative regulation of chemotaxis GO:0050922 11 0.015
ras protein signal transduction GO:0007265 77 0.015
Human
respiratory tube development GO:0030323 167 0.015
positive regulation of cell activation GO:0050867 158 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
heart morphogenesis GO:0003007 178 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
negative regulation of cellular protein catabolic process GO:1903363 22 0.015
regulation of hormone levels GO:0010817 211 0.015
heterocycle catabolic process GO:0046700 280 0.015
compound eye development GO:0048749 1 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
renal system development GO:0072001 225 0.014
skin development GO:0043588 220 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
nucleoside metabolic process GO:0009116 246 0.014
locomotory behavior GO:0007626 195 0.014
cellular homeostasis GO:0019725 240 0.014
extracellular structure organization GO:0043062 148 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
carbohydrate metabolic process GO:0005975 230 0.014
cellular chemical homeostasis GO:0055082 215 0.014
activation of immune response GO:0002253 138 0.014
anatomical structure homeostasis GO:0060249 145 0.014
blood vessel morphogenesis GO:0048514 285 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.014
regulation of notch signaling pathway GO:0008593 35 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
digestive tract development GO:0048565 190 0.014
nucleotide catabolic process GO:0009166 217 0.014
interleukin 8 production GO:0032637 4 0.014
leukocyte migration GO:0050900 124 0.014
positive regulation of cellular protein catabolic process GO:1903364 34 0.014
organic acid transport GO:0015849 101 0.014
regulation of secretion by cell GO:1903530 249 0.014
response to inorganic substance GO:0010035 96 0.014
response to molecule of bacterial origin GO:0002237 143 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
blood circulation GO:0008015 195 0.013
histone modification GO:0016570 159 0.013
purine containing compound catabolic process GO:0072523 213 0.013
cellularization GO:0007349 1 0.013
germ cell development GO:0007281 185 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.013
positive regulation of immune effector process GO:0002699 107 0.013
positive regulation of defense response GO:0031349 124 0.013
positive regulation of cell motility GO:2000147 116 0.013
cellular response to inorganic substance GO:0071241 37 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
chromatin assembly or disassembly GO:0006333 16 0.013
leukocyte mediated immunity GO:0002443 174 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
positive regulation of cell cycle GO:0045787 92 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of t cell activation GO:0050863 170 0.013
positive regulation of cell cycle phase transition GO:1901989 17 0.013
regulation of ion transport GO:0043269 215 0.013
adaptive immune response GO:0002250 155 0.013
positive regulation of innate immune response GO:0045089 80 0.013
endomembrane system organization GO:0010256 147 0.013
dna conformation change GO:0071103 37 0.013
regulation of hydrolase activity GO:0051336 246 0.013
regulation of circadian sleep wake cycle GO:0042749 3 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
nitrogen compound transport GO:0071705 271 0.013
regulation of innate immune response GO:0045088 91 0.012
regulation of translation GO:0006417 71 0.012
myeloid cell homeostasis GO:0002262 114 0.012
meiotic cell cycle GO:0051321 122 0.012
tube formation GO:0035148 140 0.012
developmental maturation GO:0021700 193 0.012
t cell differentiation GO:0030217 174 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
notch signaling pathway GO:0007219 71 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
lens development in camera type eye GO:0002088 62 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
dephosphorylation GO:0016311 129 0.012
cellular response to external stimulus GO:0071496 88 0.012
immune effector process GO:0002252 321 0.012
regulation of map kinase activity GO:0043405 120 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
positive regulation of nervous system development GO:0051962 221 0.012
negative regulation of inflammatory response GO:0050728 61 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
cellular response to lipid GO:0071396 145 0.012
telencephalon development GO:0021537 186 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
dna packaging GO:0006323 30 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
divalent inorganic cation transport GO:0072511 178 0.012
endocytosis GO:0006897 168 0.012
lung development GO:0030324 164 0.012
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.011
organelle assembly GO:0070925 177 0.011
regulation of membrane potential GO:0042391 192 0.011
regulation of blood pressure GO:0008217 93 0.011
negative regulation of cell growth GO:0030308 44 0.011
pallium development GO:0021543 120 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
sensory perception GO:0007600 245 0.011
protein oligomerization GO:0051259 67 0.011
ossification GO:0001503 216 0.011
Mouse
rna processing GO:0006396 105 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
gtp catabolic process GO:0006184 143 0.011
ear development GO:0043583 200 0.011
regulation of cell motility GO:2000145 236 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
glucose homeostasis GO:0042593 128 0.011
dna replication GO:0006260 52 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
neural tube development GO:0021915 160 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
cell fate commitment GO:0045165 210 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
regulation of organelle organization GO:0033043 289 0.011
muscle fiber development GO:0048747 76 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
cell growth GO:0016049 130 0.010
exocytosis GO:0006887 121 0.010
organophosphate catabolic process GO:0046434 232 0.010
adult walking behavior GO:0007628 41 0.010
negative regulation of endothelial cell migration GO:0010596 4 0.010
response to organic cyclic compound GO:0014070 198 0.010
maintenance of location GO:0051235 89 0.010
cellular response to nitric oxide GO:0071732 4 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
male gamete generation GO:0048232 285 0.010
gtp metabolic process GO:0046039 144 0.010
cytokine metabolic process GO:0042107 71 0.010
sperm individualization GO:0007291 1 0.010
response to endoplasmic reticulum stress GO:0034976 53 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
rho protein signal transduction GO:0007266 32 0.010
chromosome segregation GO:0007059 48 0.010
muscle cell development GO:0055001 133 0.010
epithelial cell proliferation GO:0050673 174 0.010
spermatid differentiation GO:0048515 115 0.010
regulation of muscle tissue development GO:1901861 97 0.010

Rassf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
immune system disease DOID:2914 0 0.016
sensory system disease DOID:0050155 0 0.014
bone disease DOID:0080001 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010