Mus musculus

56 known processes

Lig3

ligase III, DNA, ATP-dependent

(Aliases: D11Wsu78e,MGC78176)

Lig3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.205
dna metabolic process GO:0006259 303 0.192
cellular amino acid metabolic process GO:0006520 103 0.096
cellular response to dna damage stimulus GO:0006974 207 0.094
chromatin organization GO:0006325 206 0.092
cellular amine metabolic process GO:0044106 44 0.084
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.075
male gamete generation GO:0048232 285 0.074
positive regulation of cellular amine metabolic process GO:0033240 5 0.074
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
organonitrogen compound catabolic process GO:1901565 264 0.068
nucleoside phosphate metabolic process GO:0006753 338 0.066
cellular ketone metabolic process GO:0042180 84 0.066
organelle assembly GO:0070925 177 0.065
nucleoside triphosphate catabolic process GO:0009143 205 0.057
peptidyl amino acid modification GO:0018193 336 0.054
purine nucleotide catabolic process GO:0006195 211 0.054
protein localization to organelle GO:0033365 185 0.052
purine ribonucleotide metabolic process GO:0009150 290 0.050
purine nucleoside triphosphate metabolic process GO:0009144 226 0.050
mitotic cell cycle process GO:1903047 159 0.050
apoptotic signaling pathway GO:0097190 306 0.050
spermatogenesis GO:0007283 284 0.050
leukocyte differentiation GO:0002521 342 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.050
covalent chromatin modification GO:0016569 163 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.049
ribonucleoside metabolic process GO:0009119 245 0.048
regulation of cellular component biogenesis GO:0044087 181 0.047
organelle fission GO:0048285 170 0.047
nucleotide catabolic process GO:0009166 217 0.047
purine nucleoside triphosphate catabolic process GO:0009146 203 0.046
purine containing compound catabolic process GO:0072523 213 0.046
germ cell development GO:0007281 185 0.045
amine metabolic process GO:0009308 45 0.045
purine nucleoside catabolic process GO:0006152 205 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.043
cellular component assembly involved in morphogenesis GO:0010927 139 0.042
macromolecule glycosylation GO:0043413 55 0.041
ribonucleoside catabolic process GO:0042454 206 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
purine ribonucleoside catabolic process GO:0046130 205 0.039
macromolecule methylation GO:0043414 120 0.039
chromatin modification GO:0016568 187 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
heterocycle catabolic process GO:0046700 280 0.038
methylation GO:0032259 134 0.038
regionalization GO:0003002 337 0.038
ribonucleotide metabolic process GO:0009259 291 0.037
neural tube development GO:0021915 160 0.036
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
aromatic compound catabolic process GO:0019439 286 0.036
nucleoside catabolic process GO:0009164 206 0.036
embryonic epithelial tube formation GO:0001838 130 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
glycosyl compound metabolic process GO:1901657 246 0.035
ribonucleoside triphosphate metabolic process GO:0009199 220 0.035
nuclear division GO:0000280 158 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.035
regulation of anatomical structure size GO:0090066 178 0.034
response to radiation GO:0009314 165 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
regulation of organelle organization GO:0033043 289 0.034
oocyte axis specification GO:0007309 2 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
cell adhesion GO:0007155 329 0.033
meiotic nuclear division GO:0007126 115 0.032
ribonucleotide catabolic process GO:0009261 208 0.032
maternal determination of anterior posterior axis embryo GO:0008358 2 0.031
organophosphate catabolic process GO:0046434 232 0.031
nucleotide metabolic process GO:0009117 332 0.030
double strand break repair GO:0006302 48 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
ras protein signal transduction GO:0007265 77 0.030
skeletal system development GO:0001501 356 0.030
regulation of cell activation GO:0050865 289 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
intracellular protein transport GO:0006886 204 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
purine nucleoside metabolic process GO:0042278 241 0.028
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.028
epithelial tube formation GO:0072175 130 0.028
epidermis development GO:0008544 187 0.028
skin development GO:0043588 220 0.028
morphogenesis of embryonic epithelium GO:0016331 159 0.027
tube closure GO:0060606 91 0.027
organelle localization GO:0051640 179 0.026
morphogenesis of a polarized epithelium GO:0001738 37 0.026
establishment or maintenance of cell polarity GO:0007163 86 0.026
histone methylation GO:0016571 71 0.025
protein glycosylation GO:0006486 55 0.025
tube formation GO:0035148 140 0.025
nucleoside metabolic process GO:0009116 246 0.025
t cell activation GO:0042110 289 0.025
rac protein signal transduction GO:0016601 13 0.025
immune effector process GO:0002252 321 0.025
regulation of hydrolase activity GO:0051336 246 0.025
single organism nuclear import GO:1902593 95 0.024
embryonic organ morphogenesis GO:0048562 276 0.024
histone modification GO:0016570 159 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
oocyte anterior posterior axis specification GO:0007314 2 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
neural tube formation GO:0001841 108 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
mitotic cell cycle GO:0000278 195 0.023
lymphocyte differentiation GO:0030098 242 0.023
rna processing GO:0006396 105 0.023
protein localization to nucleus GO:0034504 121 0.023
oocyte construction GO:0007308 2 0.023
gtp metabolic process GO:0046039 144 0.023
gonad development GO:0008406 141 0.023
gtp catabolic process GO:0006184 143 0.022
cytoplasmic transport GO:0016482 234 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
microtubule based process GO:0007017 236 0.022
muscle tissue development GO:0060537 308 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
nuclear import GO:0051170 95 0.022
spermatid differentiation GO:0048515 115 0.022
gland development GO:0048732 330 0.022
cilium morphogenesis GO:0060271 102 0.022
glycosylation GO:0070085 62 0.022
actin cytoskeleton organization GO:0030036 220 0.022
digestive system development GO:0055123 200 0.022
epithelial cell development GO:0002064 159 0.022
regulation of neuron projection development GO:0010975 169 0.022
digestive tract development GO:0048565 190 0.021
carbohydrate metabolic process GO:0005975 230 0.021
glycoprotein biosynthetic process GO:0009101 89 0.021
protein import GO:0017038 101 0.021
protein targeting GO:0006605 143 0.021
purine containing compound metabolic process GO:0072521 311 0.021
single organism cell adhesion GO:0098602 156 0.021
developmental maturation GO:0021700 193 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
positive regulation of catenin import into nucleus GO:0035413 2 0.021
protein dna complex subunit organization GO:0071824 28 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
skeletal system morphogenesis GO:0048705 203 0.020
multicellular organism growth GO:0035264 161 0.020
blastocyst development GO:0001824 80 0.020
primary neural tube formation GO:0014020 95 0.020
meiotic cell cycle GO:0051321 122 0.020
cilium assembly GO:0042384 81 0.019
development of primary sexual characteristics GO:0045137 143 0.019
regulation of actin filament based process GO:0032970 99 0.019
rho protein signal transduction GO:0007266 32 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
wnt signaling pathway GO:0016055 188 0.019
fertilization GO:0009566 127 0.019
homeostasis of number of cells GO:0048872 210 0.019
extracellular structure organization GO:0043062 148 0.019
circadian regulation of gene expression GO:0032922 48 0.019
regulation of cell adhesion GO:0030155 154 0.019
sensory organ morphogenesis GO:0090596 242 0.019
septum primum development GO:0003284 4 0.019
regulation of chromatin silencing GO:0031935 2 0.019
transmission of nerve impulse GO:0019226 76 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.018
leukocyte activation involved in immune response GO:0002366 126 0.018
neuronal action potential GO:0019228 54 0.018
heart morphogenesis GO:0003007 178 0.018
regulation of organ morphogenesis GO:2000027 144 0.018
positive regulation of growth GO:0045927 104 0.018
protein methylation GO:0006479 81 0.018
regulation of defense response GO:0031347 233 0.018
stem cell development GO:0048864 219 0.018
glycoprotein metabolic process GO:0009100 116 0.018
cell fate commitment GO:0045165 210 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
cellularization GO:0007349 1 0.018
protein maturation GO:0051604 176 0.018
endocytosis GO:0006897 168 0.018
extracellular matrix organization GO:0030198 147 0.018
endodermal cell fate specification GO:0001714 4 0.018
neural tube closure GO:0001843 90 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
nuclear transport GO:0051169 139 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.017
spermatid development GO:0007286 108 0.017
spindle assembly involved in mitosis GO:0090307 4 0.017
dna modification GO:0006304 50 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
rna splicing GO:0008380 54 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
dna recombination GO:0006310 92 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
membrane organization GO:0061024 245 0.017
endomembrane system organization GO:0010256 147 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
respiratory tube development GO:0030323 167 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
regulation of protein localization GO:0032880 231 0.017
muscle cell differentiation GO:0042692 261 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
cell maturation GO:0048469 127 0.016
dna alkylation GO:0006305 43 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
regulation of neuron differentiation GO:0045664 281 0.016
gene silencing GO:0016458 38 0.016
placenta development GO:0001890 140 0.016
adaptive immune response GO:0002250 155 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
stem cell differentiation GO:0048863 268 0.016
cellular response to lipid GO:0071396 145 0.016
myelination GO:0042552 74 0.016
cellular homeostasis GO:0019725 240 0.016
axon ensheathment GO:0008366 76 0.016
regulation of protein processing GO:0070613 96 0.016
action potential GO:0001508 78 0.016
regulation of protein complex assembly GO:0043254 83 0.015
positive regulation of protein modification process GO:0031401 299 0.015
dna conformation change GO:0071103 37 0.015
protein ubiquitination GO:0016567 171 0.015
cell junction maintenance GO:0034331 4 0.015
dna methylation GO:0006306 43 0.015
respiratory system development GO:0060541 190 0.015
negative regulation of cell fate specification GO:0009996 4 0.015
female meiosis chromosome segregation GO:0016321 1 0.015
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.015
myeloid cell differentiation GO:0030099 233 0.015
intracellular mrna localization GO:0008298 4 0.015
positive regulation of nervous system development GO:0051962 221 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
ribonucleoprotein complex disassembly GO:0032988 3 0.015
maintenance of location GO:0051235 89 0.015
regulation of cytokine production GO:0001817 266 0.015
protein alkylation GO:0008213 81 0.015
axonogenesis GO:0007409 274 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
regulation of cell cycle GO:0051726 281 0.015
alpha beta t cell activation GO:0046631 91 0.015
somatic cell dna recombination GO:0016444 51 0.015
response to organonitrogen compound GO:0010243 246 0.015
cell activation involved in immune response GO:0002263 126 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
regulation of mrna splicing via spliceosome GO:0048024 32 0.015
compound eye development GO:0048749 1 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
striated muscle tissue development GO:0014706 293 0.015
wound healing GO:0042060 157 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.014
male sex differentiation GO:0046661 109 0.014
blastocyst growth GO:0001832 23 0.014
camera type eye development GO:0043010 266 0.014
cardiac chamber morphogenesis GO:0003206 93 0.014
regulation of cell projection organization GO:0031344 206 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
multicellular organismal signaling GO:0035637 91 0.014
leukocyte mediated immunity GO:0002443 174 0.014
synaptic transmission GO:0007268 329 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.014
embryonic placenta development GO:0001892 98 0.014
macromolecule catabolic process GO:0009057 281 0.014
chromosome segregation GO:0007059 48 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
b cell activation GO:0042113 161 0.014
t cell differentiation GO:0030217 174 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
protein processing GO:0016485 163 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of cellular component size GO:0032535 121 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
negative regulation of organelle organization GO:0010639 90 0.013
inflammatory response GO:0006954 244 0.013
regulation of response to wounding GO:1903034 189 0.013
regulation of membrane potential GO:0042391 192 0.013
nucleotide excision repair GO:0006289 13 0.013
cell junction organization GO:0034330 77 0.013
t cell proliferation GO:0042098 120 0.013
regulation of hormone levels GO:0010817 211 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
histone lysine methylation GO:0034968 50 0.013
cardiac chamber development GO:0003205 108 0.013
pole plasm assembly GO:0007315 2 0.013
negative regulation of cell development GO:0010721 169 0.013
negative regulation of molecular function GO:0044092 258 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
leukocyte proliferation GO:0070661 172 0.013
gastrulation GO:0007369 116 0.013
positive regulation of cell development GO:0010720 237 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
cell growth GO:0016049 130 0.012
male anatomical structure morphogenesis GO:0090598 4 0.012
response to acid chemical GO:0001101 111 0.012
blood vessel morphogenesis GO:0048514 285 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
protein import into nucleus GO:0006606 95 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.012
ensheathment of neurons GO:0007272 76 0.012
regulation of protein maturation GO:1903317 96 0.012
negative regulation of immune system process GO:0002683 209 0.012
limb development GO:0060173 166 0.012
embryonic skeletal system morphogenesis GO:0048704 91 0.012
meiosis i GO:0007127 60 0.012
regulation of hippo signaling GO:0035330 1 0.012
protein catabolic process GO:0030163 221 0.012
cellular protein complex assembly GO:0043623 116 0.012
transmembrane transport GO:0055085 412 0.012
peptidyl lysine modification GO:0018205 77 0.012
dephosphorylation GO:0016311 129 0.012
negative regulation of posttranscriptional gene silencing GO:0060149 1 0.012
embryonic skeletal system development GO:0048706 120 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
appendage morphogenesis GO:0035107 149 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
chemotaxis GO:0006935 247 0.012
establishment of planar polarity GO:0001736 28 0.012
positive regulation of cell activation GO:0050867 158 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
cellular protein catabolic process GO:0044257 155 0.012
regulation of cell size GO:0008361 72 0.012
synapse organization GO:0050808 125 0.012
activation of nf kappab inducing kinase activity GO:0007250 4 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
establishment of organelle localization GO:0051656 122 0.011
positive regulation of transferase activity GO:0051347 167 0.011
negative regulation of dna replication GO:0008156 4 0.011
regulation of t cell activation GO:0050863 170 0.011
male gonad development GO:0008584 88 0.011
spinal cord development GO:0021510 81 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
ear morphogenesis GO:0042471 118 0.011
anatomical structure homeostasis GO:0060249 145 0.011
mitotic cytokinesis GO:0000281 4 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
mrna processing GO:0006397 63 0.011
oxidation reduction process GO:0055114 342 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
translation GO:0006412 93 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.011
regulation of cellular response to stress GO:0080135 159 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
immunoglobulin mediated immune response GO:0016064 69 0.011
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
cation homeostasis GO:0055080 212 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
cell substrate adhesion GO:0031589 130 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
cellular response to peptide GO:1901653 92 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
positive regulation of wnt signaling pathway GO:0030177 45 0.011
nitrogen compound transport GO:0071705 271 0.011
cell cell junction organization GO:0045216 72 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
g1 s transition of mitotic cell cycle GO:0000082 57 0.011
fat cell differentiation GO:0045444 160 0.010
male meiosis GO:0007140 37 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
actin filament organization GO:0007015 113 0.010
macromolecular complex disassembly GO:0032984 43 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
ion transmembrane transport GO:0034220 361 0.010
lung development GO:0030324 164 0.010
response to light stimulus GO:0009416 135 0.010
meiotic cell cycle process GO:1903046 77 0.010
positive regulation of cell cycle GO:0045787 92 0.010
appendage development GO:0048736 166 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
rhythmic process GO:0048511 174 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
cell type specific apoptotic process GO:0097285 268 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
regulation of inflammatory response GO:0050727 147 0.010
positive regulation of cell death GO:0010942 224 0.010
ossification GO:0001503 216 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
nucleus organization GO:0006997 45 0.010
cation transport GO:0006812 399 0.010
digestive tract morphogenesis GO:0048546 147 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
mapk cascade GO:0000165 281 0.010
response to growth factor GO:0070848 198 0.010

Lig3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
immune system disease DOID:2914 0 0.021
musculoskeletal system disease DOID:17 0 0.018
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
hematopoietic system disease DOID:74 0 0.016
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
anemia DOID:2355 0 0.014
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
immune system cancer DOID:0060083 0 0.012
hematologic cancer DOID:2531 0 0.012