Mus musculus

16 known processes

Cdc34

cell division cycle 34 homolog (S. cerevisiae)

(Aliases: AI327276,UBE2R1)

Cdc34 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of ruffle assembly GO:1900029 1 0.250
protein modification by small protein conjugation GO:0032446 187 0.250
apoptotic signaling pathway GO:0097190 306 0.235
dephosphorylation GO:0016311 129 0.219
macromolecule catabolic process GO:0009057 281 0.215
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.201
respiratory system development GO:0060541 190 0.174
male gamete generation GO:0048232 285 0.142
spermatogenesis GO:0007283 284 0.133
ras protein signal transduction GO:0007265 77 0.125
negative regulation of ras gtpase activity GO:0034261 3 0.124
oocyte construction GO:0007308 2 0.110
regulation of cellular catabolic process GO:0031329 242 0.107
small gtpase mediated signal transduction GO:0007264 97 0.102
rap protein signal transduction GO:0032486 3 0.096
mirna metabolic process GO:0010586 10 0.094
regulation of translation GO:0006417 71 0.085
regulation of gtp catabolic process GO:0033124 113 0.085
regulation of cell cycle process GO:0010564 160 0.085
negative regulation of gtpase activity GO:0034260 6 0.083
localization within membrane GO:0051668 4 0.081
g protein coupled receptor signaling pathway GO:0007186 243 0.081
lung development GO:0030324 164 0.078
ubiquitin dependent protein catabolic process GO:0006511 129 0.075
Human
respiratory tube development GO:0030323 167 0.075
regulation of protein kinase activity GO:0045859 232 0.074
cell cycle arrest GO:0007050 37 0.071
morphogenesis of a branching epithelium GO:0061138 193 0.068
negative regulation of cell cycle GO:0045786 123 0.068
cellular protein complex assembly GO:0043623 116 0.068
stem cell differentiation GO:0048863 268 0.063
carbon catabolite regulation of transcription GO:0045990 4 0.061
rhythmic process GO:0048511 174 0.060
proteasomal protein catabolic process GO:0010498 98 0.059
Human
aromatic compound catabolic process GO:0019439 286 0.059
positive regulation of transferase activity GO:0051347 167 0.059
positive regulation of protein phosphorylation GO:0001934 242 0.058
protein targeting GO:0006605 143 0.058
positive regulation of rac protein signal transduction GO:0035022 1 0.058
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.055
generation of precursor metabolites and energy GO:0006091 103 0.054
intrinsic apoptotic signaling pathway GO:0097193 132 0.053
erk1 and erk2 cascade GO:0070371 77 0.053
positive regulation of cellular catabolic process GO:0031331 148 0.053
germ cell development GO:0007281 185 0.053
multicellular organism growth GO:0035264 161 0.052
regulation of neuron apoptotic process GO:0043523 122 0.052
mitotic cell cycle process GO:1903047 159 0.051
positive regulation of apoptotic process GO:0043065 217 0.050
negative regulation of cell cycle process GO:0010948 69 0.049
positive regulation of nucleotide catabolic process GO:0030813 88 0.049
spermatid development GO:0007286 108 0.049
positive regulation of protein modification process GO:0031401 299 0.047
negative regulation of protein metabolic process GO:0051248 282 0.047
epithelial tube morphogenesis GO:0060562 303 0.046
cellular response to hormone stimulus GO:0032870 150 0.045
photoreceptor cell morphogenesis GO:0008594 3 0.045
regulation of kinase activity GO:0043549 249 0.044
regulation of purine nucleotide catabolic process GO:0033121 122 0.044
camp metabolic process GO:0046058 40 0.044
response to nutrient levels GO:0031667 109 0.044
positive regulation of map kinase activity GO:0043406 84 0.043
gonad development GO:0008406 141 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.042
cell growth GO:0016049 130 0.042
regulation of ras gtpase activity GO:0032318 88 0.042
homeostasis of number of cells GO:0048872 210 0.042
branching morphogenesis of an epithelial tube GO:0048754 159 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.040
carbohydrate metabolic process GO:0005975 230 0.039
regulation of actin cytoskeleton organization GO:0032956 84 0.038
gene silencing by rna GO:0031047 19 0.037
regulation of glycogen catabolic process GO:0005981 2 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.037
Human
development of primary sexual characteristics GO:0045137 143 0.037
positive regulation of apoptotic signaling pathway GO:2001235 95 0.037
spermatid differentiation GO:0048515 115 0.037
leukocyte differentiation GO:0002521 342 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
positive regulation of rap gtpase activity GO:0032854 3 0.036
muscle cell differentiation GO:0042692 261 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
protein localization to mitochondrion GO:0070585 15 0.035
compound eye development GO:0048749 1 0.035
carbon catabolite activation of transcription GO:0045991 4 0.034
purine nucleoside metabolic process GO:0042278 241 0.034
regulation of cell motility GO:2000145 236 0.034
organonitrogen compound catabolic process GO:1901565 264 0.033
rna interference GO:0016246 2 0.033
organelle assembly GO:0070925 177 0.033
response to radiation GO:0009314 165 0.033
rho protein signal transduction GO:0007266 32 0.032
negative regulation of neuron death GO:1901215 98 0.032
positive regulation of hydrolase activity GO:0051345 148 0.032
oogenesis GO:0048477 56 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
positive regulation of protein kinase activity GO:0045860 144 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
protein transmembrane transport GO:0071806 8 0.031
regulation of ras protein signal transduction GO:0046578 114 0.031
regulation of defense response GO:0031347 233 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
myosin filament organization GO:0031033 3 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.030
regulation of ruffle assembly GO:1900027 8 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
negative regulation of phosphorus metabolic process GO:0010563 184 0.030
gene silencing GO:0016458 38 0.030
positive regulation of nervous system development GO:0051962 221 0.030
negative regulation of cell cycle phase transition GO:1901988 48 0.030
neuron death GO:0070997 154 0.029
rac protein signal transduction GO:0016601 13 0.029
female gamete generation GO:0007292 74 0.029
response to organonitrogen compound GO:0010243 246 0.029
exocytosis GO:0006887 121 0.029
negative regulation of cell motility GO:2000146 61 0.029
regulation of cell cycle phase transition GO:1901987 77 0.029
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.029
cell cycle checkpoint GO:0000075 47 0.029
heterocycle catabolic process GO:0046700 280 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
mitotic cell cycle GO:0000278 195 0.028
regulation of erk1 and erk2 cascade GO:0070372 71 0.028
positive regulation of mapk cascade GO:0043410 170 0.027
establishment of protein localization to organelle GO:0072594 118 0.027
regulation of muscle tissue development GO:1901861 97 0.027
oxidation reduction process GO:0055114 342 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
stress activated mapk cascade GO:0051403 80 0.026
positive regulation of ras gtpase activity GO:0032320 65 0.026
positive regulation of cell migration GO:0030335 109 0.026
modification dependent macromolecule catabolic process GO:0043632 133 0.026
Human
positive regulation of cell projection organization GO:0031346 95 0.026
organophosphate catabolic process GO:0046434 232 0.026
pyridine containing compound catabolic process GO:0072526 4 0.026
mitotic cell cycle checkpoint GO:0007093 31 0.026
actin cytoskeleton organization GO:0030036 220 0.026
activation of adenylate cyclase activity GO:0007190 4 0.025
regulation of actin filament based process GO:0032970 99 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of neuron death GO:1901214 134 0.025
regulation of transferase activity GO:0051338 263 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
cellular response to external stimulus GO:0071496 88 0.025
amine metabolic process GO:0009308 45 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
Human
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.024
ovarian follicle development GO:0001541 40 0.024
positive regulation of gtp catabolic process GO:0033126 85 0.024
negative regulation of nucleoside metabolic process GO:0045978 11 0.024
developmental cell growth GO:0048588 84 0.024
striated muscle tissue development GO:0014706 293 0.024
regulation of protein processing GO:0070613 96 0.024
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.024
response to heat GO:0009408 27 0.024
response to extracellular stimulus GO:0009991 127 0.024
photoreceptor cell differentiation GO:0046530 52 0.024
rna processing GO:0006396 105 0.023
response to oxidative stress GO:0006979 123 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
photoreceptor cell development GO:0042461 40 0.023
regulation of stress activated mapk cascade GO:0032872 69 0.022
regulation of cell migration GO:0030334 219 0.022
cell maturation GO:0048469 127 0.022
protein targeting to mitochondrion GO:0006626 6 0.022
regulation of exocytosis GO:0017157 61 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
visual behavior GO:0007632 45 0.022
positive regulation of cell development GO:0010720 237 0.022
regulation of cell cycle GO:0051726 281 0.022
negative regulation of mitotic cell cycle GO:0045930 58 0.021
ruffle organization GO:0031529 16 0.021
defense response to other organism GO:0098542 197 0.021
intracellular protein transport GO:0006886 204 0.021
female gonad development GO:0008585 71 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
regulation of rho gtpase activity GO:0032319 58 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
muscle cell development GO:0055001 133 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
jnk cascade GO:0007254 72 0.020
positive regulation of gtpase activity GO:0043547 85 0.020
cellular senescence GO:0090398 11 0.020
response to light stimulus GO:0009416 135 0.020
cell aging GO:0007569 35 0.020
positive regulation of transcription by galactose GO:0000411 1 0.020
positive regulation of jnk cascade GO:0046330 46 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
positive regulation of mirna metabolic process GO:2000630 1 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
regulation of t cell activation GO:0050863 170 0.020
multi organism behavior GO:0051705 62 0.019
purine containing compound biosynthetic process GO:0072522 70 0.019
cell type specific apoptotic process GO:0097285 268 0.019
regulation of mapk cascade GO:0043408 248 0.019
circadian rhythm GO:0007623 114 0.019
protein ubiquitination GO:0016567 171 0.019
regulation of cyclase activity GO:0031279 13 0.019
positive regulation of cell motility GO:2000147 116 0.019
learning or memory GO:0007611 148 0.019
regulation of jnk cascade GO:0046328 62 0.019
stress activated protein kinase signaling cascade GO:0031098 81 0.018
regulation of protein catabolic process GO:0042176 108 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.018
visual learning GO:0008542 44 0.018
translation GO:0006412 93 0.018
regulation of map kinase activity GO:0043405 120 0.018
positive regulation of ras protein signal transduction GO:0046579 13 0.018
negative regulation of nucleotide metabolic process GO:0045980 16 0.018
innate immune response GO:0045087 157 0.018
mitochondrion organization GO:0007005 134 0.018
peptidyl amino acid modification GO:0018193 336 0.018
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.018
ribose phosphate biosynthetic process GO:0046390 59 0.018
cellular response to extracellular stimulus GO:0031668 81 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
protein catabolic process GO:0030163 221 0.018
Human
regulation of response to wounding GO:1903034 189 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
Human
epithelial cell proliferation GO:0050673 174 0.018
positive regulation of kinase activity GO:0033674 155 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
negative regulation of molecular function GO:0044092 258 0.017
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.017
developmental maturation GO:0021700 193 0.017
endocytosis GO:0006897 168 0.017
ncrna processing GO:0034470 26 0.017
negative regulation of cell migration GO:0030336 59 0.017
negative regulation of cellular catabolic process GO:0031330 47 0.017
negative regulation of translational initiation GO:0045947 4 0.017
positive regulation of growth hormone receptor signaling pathway GO:0060399 3 0.017
rna catabolic process GO:0006401 29 0.017
wnt signaling pathway GO:0016055 188 0.016
chromatin organization GO:0006325 206 0.016
regulation of cellular response to stress GO:0080135 159 0.016
negative regulation of nucleotide catabolic process GO:0030812 9 0.016
dna metabolic process GO:0006259 303 0.016
gland development GO:0048732 330 0.016
positive regulation of camp biosynthetic process GO:0030819 19 0.016
establishment of protein localization to mitochondrion GO:0072655 11 0.016
positive regulation of rho gtpase activity GO:0032321 41 0.016
sister chromatid segregation GO:0000819 20 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of rho protein signal transduction GO:0035023 71 0.016
peptidyl serine modification GO:0018209 83 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
protein localization to organelle GO:0033365 185 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
ovulation cycle GO:0042698 59 0.016
protein processing GO:0016485 163 0.016
cellular response to nutrient levels GO:0031669 64 0.015
response to organic cyclic compound GO:0014070 198 0.015
organic acid transport GO:0015849 101 0.015
cytokine production GO:0001816 319 0.015
regulation of cellular amino acid metabolic process GO:0006521 5 0.015
regulation of rac protein signal transduction GO:0035020 19 0.015
positive regulation of organelle organization GO:0010638 128 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
positive regulation of activin receptor signaling pathway GO:0032927 3 0.015
glucose metabolic process GO:0006006 92 0.015
development of primary female sexual characteristics GO:0046545 73 0.015
skeletal muscle organ development GO:0060538 163 0.015
nucleoside catabolic process GO:0009164 206 0.015
t cell differentiation in thymus GO:0033077 77 0.014
t cell activation GO:0042110 289 0.014
cyclic purine nucleotide metabolic process GO:0052652 43 0.014
cellular amine metabolic process GO:0044106 44 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
organ growth GO:0035265 117 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
cell cycle g1 s phase transition GO:0044843 57 0.014
histone h4 k16 acetylation GO:0043984 3 0.014
positive regulation of epithelial cell proliferation GO:0050679 68 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
glucan catabolic process GO:0009251 5 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
oocyte differentiation GO:0009994 35 0.014
regulation of organelle organization GO:0033043 289 0.014
b cell activation GO:0042113 161 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
single organism nuclear import GO:1902593 95 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
female sex differentiation GO:0046660 84 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.013
t cell differentiation GO:0030217 174 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
transmembrane transport GO:0055085 412 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
nucleoside metabolic process GO:0009116 246 0.013
regulation of cell activation GO:0050865 289 0.013
regulation of anatomical structure size GO:0090066 178 0.012
cellular response to peptide GO:1901653 92 0.012
cognition GO:0050890 149 0.012
regulation of hydrolase activity GO:0051336 246 0.012
lymphocyte differentiation GO:0030098 242 0.012
positive regulation of defense response GO:0031349 124 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
adiponectin activated signaling pathway GO:0033211 4 0.012
hormone mediated signaling pathway GO:0009755 23 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
negative regulation of organelle organization GO:0010639 90 0.012
muscle tissue development GO:0060537 308 0.012
microtubule based process GO:0007017 236 0.012
regulation of secretion GO:0051046 274 0.012
response to temperature stimulus GO:0009266 55 0.012
response to oxygen levels GO:0070482 62 0.012
regulation of glucose metabolic process GO:0010906 60 0.012
cell adhesion GO:0007155 329 0.012
cyclic nucleotide biosynthetic process GO:0009190 44 0.012
response to endoplasmic reticulum stress GO:0034976 53 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
neuron apoptotic process GO:0051402 142 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.012
regulation of camp biosynthetic process GO:0030817 25 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of neuron differentiation GO:0045664 281 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
regulation of secretion by cell GO:1903530 249 0.012
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.012
regulation of cell projection assembly GO:0060491 38 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
positive regulation of viral genome replication GO:0045070 2 0.011
regulation of cellular component size GO:0032535 121 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
transition metal ion homeostasis GO:0055076 54 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.011
stem cell fate commitment GO:0048865 5 0.011
response to starvation GO:0042594 65 0.011
intraspecies interaction between organisms GO:0051703 21 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
response to peptide hormone GO:0043434 127 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
glucan metabolic process GO:0044042 32 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
purine containing compound metabolic process GO:0072521 311 0.011
synaptic transmission gabaergic GO:0051932 19 0.011
digestive system development GO:0055123 200 0.011
positive regulation of stress activated mapk cascade GO:0032874 48 0.011
single organism cell adhesion GO:0098602 156 0.011
regulation of dna replication GO:0006275 17 0.011
associative learning GO:0008306 61 0.011
protein maturation GO:0051604 176 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.011
peripheral nervous system development GO:0007422 53 0.011
positive regulation of response to wounding GO:1903036 66 0.011
negative regulation of protein maturation GO:1903318 79 0.011
positive regulation of rac gtpase activity GO:0032855 14 0.010
erbb signaling pathway GO:0038127 32 0.010
immune effector process GO:0002252 321 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
chromosome separation GO:0051304 14 0.010
regulation of carbohydrate biosynthetic process GO:0043255 40 0.010
regulation of chromosome organization GO:0033044 83 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
lung morphogenesis GO:0060425 50 0.010
gliogenesis GO:0042063 141 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
regulation of cell size GO:0008361 72 0.010
myotube differentiation GO:0014902 105 0.010
mapk cascade GO:0000165 281 0.010
regulation of response to osmotic stress GO:0047484 3 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
proprioception GO:0019230 4 0.010
digestive tract morphogenesis GO:0048546 147 0.010
response to peptide GO:1901652 136 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010

Cdc34 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.163
disease of cellular proliferation DOID:14566 0 0.163
organ system cancer DOID:0050686 0 0.163
endocrine gland cancer DOID:170 0 0.025
thyroid cancer DOID:1781 0 0.025
central nervous system disease DOID:331 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016