Mus musculus

50 known processes

Brwd1

bromodomain and WD repeat domain containing 1

(Aliases: G1-403-16,D530019K20Rik,5330419I02Rik,Wdr9,repro5)

Brwd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.345
regulation of cellular ketone metabolic process GO:0010565 66 0.225
peptidyl amino acid modification GO:0018193 336 0.199
Mouse
chromatin organization GO:0006325 206 0.189
chromatin modification GO:0016568 187 0.162
histone h3 k4 methylation GO:0051568 23 0.133
heterocycle catabolic process GO:0046700 280 0.113
mitotic cell cycle GO:0000278 195 0.108
Mouse Fly
regulation of histone methylation GO:0031060 30 0.108
aromatic compound catabolic process GO:0019439 286 0.095
histone modification GO:0016570 159 0.090
cellular ketone metabolic process GO:0042180 84 0.087
macromolecule methylation GO:0043414 120 0.082
actin cytoskeleton organization GO:0030036 220 0.074
ras protein signal transduction GO:0007265 77 0.073
histone h3 k4 trimethylation GO:0080182 5 0.071
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
axonogenesis GO:0007409 274 0.067
cellular amino acid metabolic process GO:0006520 103 0.066
histone methylation GO:0016571 71 0.063
rho protein signal transduction GO:0007266 32 0.062
carbohydrate metabolic process GO:0005975 230 0.061
nucleoside triphosphate catabolic process GO:0009143 205 0.060
gonad development GO:0008406 141 0.059
regulation of organelle organization GO:0033043 289 0.059
Mouse
actin filament organization GO:0007015 113 0.057
dna metabolic process GO:0006259 303 0.055
small gtpase mediated signal transduction GO:0007264 97 0.055
methylation GO:0032259 134 0.055
ribonucleoside metabolic process GO:0009119 245 0.053
dna repair GO:0006281 107 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.049
peptidyl serine phosphorylation GO:0018105 74 0.048
Mouse
macromolecule catabolic process GO:0009057 281 0.045
purine nucleotide catabolic process GO:0006195 211 0.045
chemotaxis GO:0006935 247 0.043
nucleotide metabolic process GO:0009117 332 0.043
positive regulation of protein modification process GO:0031401 299 0.043
Mouse
ribonucleotide metabolic process GO:0009259 291 0.043
purine nucleoside catabolic process GO:0006152 205 0.041
organic cyclic compound catabolic process GO:1901361 295 0.041
regulation of cellular catabolic process GO:0031329 242 0.040
regulation of neuron differentiation GO:0045664 281 0.040
posttranscriptional regulation of gene expression GO:0010608 155 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
protein methylation GO:0006479 81 0.038
forebrain development GO:0030900 302 0.037
ribonucleotide catabolic process GO:0009261 208 0.037
spermatogenesis GO:0007283 284 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
peptidyl lysine modification GO:0018205 77 0.037
central nervous system neuron differentiation GO:0021953 162 0.036
regulation of cellular component biogenesis GO:0044087 181 0.036
endocytosis GO:0006897 168 0.036
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.035
male gamete generation GO:0048232 285 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.035
muscle cell differentiation GO:0042692 261 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.035
purine containing compound metabolic process GO:0072521 311 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
Mouse
neuron projection guidance GO:0097485 141 0.033
mrna metabolic process GO:0016071 84 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
regulation of mapk cascade GO:0043408 248 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
peptidyl lysine methylation GO:0018022 29 0.032
respiratory system development GO:0060541 190 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
epithelial cell development GO:0002064 159 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
homeostasis of number of cells GO:0048872 210 0.030
bmp signaling pathway GO:0030509 93 0.030
camera type eye development GO:0043010 266 0.030
protein alkylation GO:0008213 81 0.030
establishment of vesicle localization GO:0051650 81 0.029
mapk cascade GO:0000165 281 0.029
regulation of anatomical structure size GO:0090066 178 0.029
establishment of organelle localization GO:0051656 122 0.028
dendrite development GO:0016358 115 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.027
actin filament polymerization GO:0030041 44 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
nucleoside catabolic process GO:0009164 206 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
cytokine production GO:0001816 319 0.027
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
positive regulation of nervous system development GO:0051962 221 0.027
skeletal system development GO:0001501 356 0.026
regulation of cell motility GO:2000145 236 0.026
peptidyl lysine trimethylation GO:0018023 12 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
regulation of ras protein signal transduction GO:0046578 114 0.025
synaptic transmission GO:0007268 329 0.025
regulation of cell projection organization GO:0031344 206 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
cardiac chamber morphogenesis GO:0003206 93 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
response to acid chemical GO:0001101 111 0.025
regulation of carbohydrate metabolic process GO:0006109 75 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
cellular protein complex assembly GO:0043623 116 0.025
multicellular organism growth GO:0035264 161 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
gene silencing by mirna GO:0035195 10 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
Fly
developmental maturation GO:0021700 193 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
regulation of cellular response to stress GO:0080135 159 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
posttranscriptional gene silencing by rna GO:0035194 10 0.023
regionalization GO:0003002 337 0.023
protein catabolic process GO:0030163 221 0.023
cation transport GO:0006812 399 0.023
actin polymerization or depolymerization GO:0008154 54 0.023
telencephalon development GO:0021537 186 0.023
regulation of gtp catabolic process GO:0033124 113 0.023
nucleoside metabolic process GO:0009116 246 0.023
endomembrane system organization GO:0010256 147 0.023
cell adhesion GO:0007155 329 0.022
regulation of cellular component size GO:0032535 121 0.022
regulation of rho protein signal transduction GO:0035023 71 0.022
protein autophosphorylation GO:0046777 61 0.022
gland development GO:0048732 330 0.022
Fly
cell maturation GO:0048469 127 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
response to radiation GO:0009314 165 0.022
gene silencing GO:0016458 38 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
Mouse
purine nucleoside metabolic process GO:0042278 241 0.022
response to light stimulus GO:0009416 135 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
myeloid cell differentiation GO:0030099 233 0.022
cellular amine metabolic process GO:0044106 44 0.022
neuronal action potential GO:0019228 54 0.021
stem cell differentiation GO:0048863 268 0.021
organelle localization GO:0051640 179 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
Mouse
purine nucleotide metabolic process GO:0006163 302 0.021
response to peptide hormone GO:0043434 127 0.021
Mouse
regulation of actin filament based process GO:0032970 99 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
positive regulation of cellular component biogenesis GO:0044089 94 0.020
regulation of nucleoside metabolic process GO:0009118 130 0.020
sensory perception GO:0007600 245 0.020
nucleotide catabolic process GO:0009166 217 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
regulation of hormone levels GO:0010817 211 0.020
cellular chemical homeostasis GO:0055082 215 0.020
germ cell development GO:0007281 185 0.020
organelle fission GO:0048285 170 0.020
Mouse
cellular homeostasis GO:0019725 240 0.020
sensory organ morphogenesis GO:0090596 242 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
cell type specific apoptotic process GO:0097285 268 0.019
leukocyte differentiation GO:0002521 342 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
rna processing GO:0006396 105 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
Fly
maintenance of location GO:0051235 89 0.019
regulation of response to drug GO:2001023 2 0.018
action potential GO:0001508 78 0.018
vesicle localization GO:0051648 86 0.018
intracellular protein transport GO:0006886 204 0.018
Mouse
epithalamus development GO:0021538 2 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
spermatid differentiation GO:0048515 115 0.018
protein polymerization GO:0051258 57 0.018
microtubule based process GO:0007017 236 0.018
response to uv GO:0009411 44 0.018
respiratory tube development GO:0030323 167 0.018
ear morphogenesis GO:0042471 118 0.018
regulation of protein localization GO:0032880 231 0.017
multi multicellular organism process GO:0044706 109 0.017
regulation of secretion GO:0051046 274 0.017
protein glycosylation GO:0006486 55 0.017
regulation of bmp signaling pathway GO:0030510 60 0.017
myotube differentiation GO:0014902 105 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
histone h4 k16 acetylation GO:0043984 3 0.017
cellular response to lipid GO:0071396 145 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
divalent inorganic cation transport GO:0072511 178 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
inner ear morphogenesis GO:0042472 101 0.017
sensory perception of sound GO:0007605 97 0.016
cytoplasmic transport GO:0016482 234 0.016
Mouse
cell substrate adhesion GO:0031589 130 0.016
cation homeostasis GO:0055080 212 0.016
internal protein amino acid acetylation GO:0006475 42 0.016
ventricular septum development GO:0003281 42 0.016
purine containing compound catabolic process GO:0072523 213 0.016
ectoderm formation GO:0001705 3 0.016
negative regulation of cell development GO:0010721 169 0.016
regulation of neuron projection development GO:0010975 169 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
establishment of synaptic vesicle localization GO:0097480 57 0.016
cell growth GO:0016049 130 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of cell migration GO:0030334 219 0.016
compound eye development GO:0048749 1 0.015
histone lysine methylation GO:0034968 50 0.015
development of primary sexual characteristics GO:0045137 143 0.015
cellular response to starvation GO:0009267 57 0.015
amide transport GO:0042886 138 0.015
oxidation reduction process GO:0055114 342 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
gastrulation GO:0007369 116 0.015
synaptic vesicle localization GO:0097479 59 0.015
amine metabolic process GO:0009308 45 0.015
regulation of rho gtpase activity GO:0032319 58 0.015
cation transmembrane transport GO:0098655 266 0.015
nitrogen compound transport GO:0071705 271 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
response to nutrient levels GO:0031667 109 0.015
dorsal ventral axon guidance GO:0033563 3 0.015
renal system development GO:0072001 225 0.015
blood vessel morphogenesis GO:0048514 285 0.015
muscle contraction GO:0006936 101 0.014
histone acetylation GO:0016573 41 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
apoptotic signaling pathway GO:0097190 306 0.014
positive regulation of growth GO:0045927 104 0.014
response to organonitrogen compound GO:0010243 246 0.014
Mouse
rhythmic process GO:0048511 174 0.014
positive regulation of cell death GO:0010942 224 0.014
Fly
adaptive immune response GO:0002250 155 0.014
rac protein signal transduction GO:0016601 13 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of protein stability GO:0031647 52 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
cellular lipid metabolic process GO:0044255 323 0.014
posttranscriptional gene silencing GO:0016441 10 0.014
cranial nerve development GO:0021545 41 0.014
peptidyl serine modification GO:0018209 83 0.014
Mouse
habenula development GO:0021986 2 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
nerve development GO:0021675 67 0.014
negative regulation of immune system process GO:0002683 209 0.014
chromatin remodeling GO:0006338 32 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
endodermal cell fate specification GO:0001714 4 0.014
positive regulation of organelle organization GO:0010638 128 0.014
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
regulation of chromatin organization GO:1902275 57 0.014
mesenchyme development GO:0060485 152 0.014
female gamete generation GO:0007292 74 0.014
metal ion homeostasis GO:0055065 189 0.014
protein localization to organelle GO:0033365 185 0.013
Mouse
regulation of protein complex assembly GO:0043254 83 0.013
digestive system development GO:0055123 200 0.013
meiotic cell cycle GO:0051321 122 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
regulation of cytokine production GO:0001817 266 0.013
positive regulation of kinase activity GO:0033674 155 0.013
cardiac ventricle development GO:0003231 83 0.013
exocytosis GO:0006887 121 0.013
embryonic placenta development GO:0001892 98 0.013
visceral motor neuron differentiation GO:0021524 3 0.013
regulation of chromosome organization GO:0033044 83 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
axon guidance GO:0007411 141 0.013
extracellular structure organization GO:0043062 148 0.013
digestive tract development GO:0048565 190 0.013
regulation of cell substrate adhesion GO:0010810 73 0.013
regulation of secretion by cell GO:1903530 249 0.013
hindbrain development GO:0030902 128 0.013
regulation of response to wounding GO:1903034 189 0.013
cognition GO:0050890 149 0.013
erythrocyte differentiation GO:0030218 88 0.013
defecation GO:0030421 1 0.013
calcium ion homeostasis GO:0055074 127 0.013
protein localization to nucleus GO:0034504 121 0.013
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
mitotic cell cycle process GO:1903047 159 0.013
Mouse Fly
wnt signaling pathway GO:0016055 188 0.013
negative regulation of organelle organization GO:0010639 90 0.013
positive regulation of protein catabolic process GO:0045732 60 0.012
rna interference GO:0016246 2 0.012
stem cell development GO:0048864 219 0.012
digestive tract morphogenesis GO:0048546 147 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
interspecies interaction between organisms GO:0044419 83 0.012
cardiac chamber development GO:0003205 108 0.012
blastocyst development GO:0001824 80 0.012
striated muscle cell development GO:0055002 125 0.012
adult behavior GO:0030534 135 0.012
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.012
protein targeting GO:0006605 143 0.012
Mouse
lymphocyte mediated immunity GO:0002449 139 0.012
regulation of cell cycle GO:0051726 281 0.012
Mouse Fly
regulation of kinase activity GO:0043549 249 0.012
response to peptide GO:1901652 136 0.012
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.012
positive regulation of cell motility GO:2000147 116 0.012
male sex differentiation GO:0046661 109 0.012
myelination GO:0042552 74 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
peptidyl threonine phosphorylation GO:0018107 31 0.012
Mouse
peptidyl lysine acetylation GO:0018394 45 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
cellular response to acid chemical GO:0071229 68 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.012
rna catabolic process GO:0006401 29 0.012
negative regulation of nervous system development GO:0051961 156 0.012
tube formation GO:0035148 140 0.012
synapse organization GO:0050808 125 0.012
dna methylation GO:0006306 43 0.012
genetic imprinting GO:0071514 27 0.012
phosphatidylinositol phosphorylation GO:0046854 23 0.012
muscle system process GO:0003012 141 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
wound healing GO:0042060 157 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
stem cell proliferation GO:0072089 117 0.012
cellular protein catabolic process GO:0044257 155 0.012
biomineral tissue development GO:0031214 64 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
fertilization GO:0009566 127 0.012
regulation of actin filament polymerization GO:0030833 38 0.012
female sex differentiation GO:0046660 84 0.012
receptor mediated endocytosis GO:0006898 51 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
regulation of multi organism process GO:0043900 111 0.012
neural tube closure GO:0001843 90 0.012
nuclear division GO:0000280 158 0.012
Mouse
dna alkylation GO:0006305 43 0.012
artery development GO:0060840 53 0.012
organophosphate catabolic process GO:0046434 232 0.012
myeloid cell homeostasis GO:0002262 114 0.011
gene silencing by rna GO:0031047 19 0.011
learning or memory GO:0007611 148 0.011
formation of primary germ layer GO:0001704 77 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
negative regulation of molecular function GO:0044092 258 0.011
divalent metal ion transport GO:0070838 172 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
regulation of membrane potential GO:0042391 192 0.011
regulation of cardiac chamber morphogenesis GO:1901219 2 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.011
urogenital system development GO:0001655 261 0.011
primary neural tube formation GO:0014020 95 0.011
immune effector process GO:0002252 321 0.011
double strand break repair GO:0006302 48 0.011
neural tube development GO:0021915 160 0.011
neuromuscular process GO:0050905 99 0.011
regulation of protein catabolic process GO:0042176 108 0.011
histone h3 k9 trimethylation GO:0036124 6 0.011
septum primum development GO:0003284 4 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
appendage development GO:0048736 166 0.011
male gonad development GO:0008584 88 0.011
regulation of cell cycle process GO:0010564 160 0.011
Mouse Fly
placenta development GO:0001890 140 0.011
positive regulation of chromatin modification GO:1903310 28 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
atp metabolic process GO:0046034 75 0.011
cell recognition GO:0008037 83 0.011
positive regulation of dna templated transcription elongation GO:0032786 2 0.011
neural precursor cell proliferation GO:0061351 121 0.011
regulation of stem cell proliferation GO:0072091 78 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
circadian regulation of gene expression GO:0032922 48 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
transmission of nerve impulse GO:0019226 76 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
peptide transport GO:0015833 133 0.011
regulation of cell adhesion GO:0030155 154 0.011
negative regulation of defense response GO:0031348 77 0.011
regulation of actin filament length GO:0030832 45 0.010
sequestering of metal ion GO:0051238 19 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
small molecule biosynthetic process GO:0044283 132 0.010
spermatid development GO:0007286 108 0.010
ion transmembrane transport GO:0034220 361 0.010
tissue homeostasis GO:0001894 115 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
monosaccharide biosynthetic process GO:0046364 44 0.010
positive regulation of transferase activity GO:0051347 167 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
demethylation GO:0070988 23 0.010
regulation of cell activation GO:0050865 289 0.010
positive regulation of histone modification GO:0031058 28 0.010
locomotory behavior GO:0007626 195 0.010
response to insulin GO:0032868 100 0.010
Mouse

Brwd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.031
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.023
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
osteochondrodysplasia DOID:2256 0 0.014
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
immune system cancer DOID:0060083 0 0.011
hematologic cancer DOID:2531 0 0.011