|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.870
|
Worm |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.667
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.643
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
6 |
0.540
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.447
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.443
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.372
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.362
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.361
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.325
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.320
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.302
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.301
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.300
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
7 |
0.289
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.280
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.280
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.278
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.249
|
Worm |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.247
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.245
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.245
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.237
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.233
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.217
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.213
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.206
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.203
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.187
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.178
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.174
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.173
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.172
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.168
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.168
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.167
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.167
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.166
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.165
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.163
|
Human |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.160
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.157
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.155
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.154
|
Mouse |
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.153
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.151
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.150
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.148
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.147
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.147
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.144
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.142
|
|
|
|
negative regulation of phospholipase activity
|
GO:0010519 |
4 |
0.142
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.140
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.139
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.138
|
|
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.138
|
Fly |
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.137
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.135
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.135
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.134
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.133
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.132
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.130
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.130
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.129
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.127
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.124
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.124
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.123
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.122
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.122
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.122
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.121
|
Mouse |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.121
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.121
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.120
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.119
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.119
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.119
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.119
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.118
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.117
|
Mouse |
|
|
positive regulation of non canonical wnt signaling pathway
|
GO:2000052 |
6 |
0.117
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.115
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.115
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.114
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.114
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.112
|
Fly |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.112
|
Mouse |
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.112
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.110
|
|
|
|
learning
|
GO:0007612 |
98 |
0.109
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.109
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.108
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.107
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.106
|
Mouse |
|
|
organic anion transport
|
GO:0015711 |
137 |
0.105
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.102
|
Mouse |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.102
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.101
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.101
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.100
|
Worm |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.100
|
Fly |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.099
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.097
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.096
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.096
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.095
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.094
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.094
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.093
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.093
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.092
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.092
|
Worm |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.092
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.092
|
Human Mouse |
|
|
establishment of tissue polarity
|
GO:0007164 |
28 |
0.089
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.088
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.088
|
|
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.088
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.088
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.087
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.087
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.087
|
Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.087
|
Mouse |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.087
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.086
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.084
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.084
|
Worm |
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.083
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.083
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.082
|
Fly |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.082
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.081
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
165 |
0.080
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.080
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.080
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.080
|
Human Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.078
|
Fly |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.078
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.077
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.076
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.076
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.076
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.076
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.076
|
Human Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.075
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.075
|
Worm |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.075
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.075
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.074
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.074
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.073
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.073
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.073
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.073
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.072
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.072
|
Mouse |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.072
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.071
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.071
|
Mouse |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.071
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.070
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.070
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.069
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.069
|
Human Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.069
|
Mouse Fly |
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.069
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.069
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.069
|
Fly |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.068
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.068
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.068
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.068
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.067
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.067
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.066
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
10 |
0.066
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.066
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.066
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.066
|
Worm |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.066
|
Worm |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.065
|
Worm |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.064
|
Mouse Fly |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.063
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.063
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.063
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.063
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.062
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.062
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
28 |
0.062
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.062
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.062
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.061
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.061
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.061
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.060
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.060
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.060
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.060
|
Mouse |
|
|
anion transport
|
GO:0006820 |
177 |
0.059
|
|
|
|
negative regulation of apoptotic cell clearance
|
GO:2000426 |
1 |
0.059
|
Worm |
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.059
|
Worm |
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.058
|
Worm |
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.058
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.058
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.058
|
Mouse |
|
|
thymus development
|
GO:0048538 |
41 |
0.057
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.057
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.056
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.056
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.056
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.055
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.055
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.055
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.055
|
Mouse |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.055
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.054
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.054
|
Fly |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.054
|
Mouse Fly |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.054
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.053
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.053
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.053
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.053
|
Mouse |
|
|
neuron death
|
GO:0070997 |
154 |
0.053
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.053
|
Fly |
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.053
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.052
|
Mouse |
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.052
|
Human Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.052
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.052
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.052
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.052
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.052
|
Mouse Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.052
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.052
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.051
|
Mouse Fly |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.051
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.051
|
Fly |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.051
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.051
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.050
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.050
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.050
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
168 |
0.050
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.050
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.050
|
|
|
|
substrate dependent cell migration cell extension
|
GO:0006930 |
4 |
0.050
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.049
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.049
|
Mouse Worm |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.049
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.049
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.049
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.049
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.049
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.049
|
Mouse Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.049
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.048
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.048
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.048
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.048
|
Human Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.048
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.048
|
|
|
|
positive regulation of interferon gamma secretion
|
GO:1902715 |
3 |
0.048
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.047
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.047
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.047
|
Human Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.047
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.047
|
Human Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.047
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.047
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.046
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.046
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.046
|
Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.045
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.045
|
Mouse |
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.045
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.045
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.045
|
Worm |
|
|
lipid localization
|
GO:0010876 |
126 |
0.045
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.045
|
Fly |
|
|
kidney development
|
GO:0001822 |
213 |
0.044
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
3 |
0.044
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.044
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.044
|
Worm |
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.044
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.044
|
Mouse |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.044
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.043
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.043
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.043
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.043
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.042
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.041
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.041
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.041
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.041
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.041
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
6 |
0.041
|
Mouse |
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.040
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.040
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.040
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.040
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.040
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.040
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.039
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.039
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.039
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.039
|
Fly |
|
|
positive regulation of wnt signaling pathway planar cell polarity pathway
|
GO:2000096 |
5 |
0.039
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.039
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.038
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.038
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.038
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.038
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.038
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.038
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.038
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.038
|
Fly |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.038
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.037
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.037
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.037
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.037
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.037
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.037
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.037
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.037
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.035
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.035
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.035
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.035
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.035
|
Fly |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.035
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.035
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.035
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.034
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.034
|
Fly |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.034
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.034
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.034
|
Human Mouse |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.034
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.034
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.034
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.034
|
Worm |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.033
|
Mouse |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.033
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.033
|
|
|
|
immature b cell differentiation
|
GO:0002327 |
10 |
0.033
|
Mouse |
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.033
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.033
|
Mouse |
|
|
neuroblast fate commitment
|
GO:0014017 |
1 |
0.033
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.033
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.033
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.033
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.032
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.032
|
Fly |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.032
|
Mouse |
|
|
negative regulation of cellular senescence
|
GO:2000773 |
3 |
0.032
|
Mouse |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.032
|
Human Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.032
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.032
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.031
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.031
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.031
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.031
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.031
|
|
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
3 |
0.031
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.031
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.031
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.031
|
Mouse |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.031
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.031
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.030
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.030
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.030
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.030
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.030
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.030
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.030
|
Worm |
|
|
fertilization
|
GO:0009566 |
127 |
0.030
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.030
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.030
|
Fly |
|
|
forebrain development
|
GO:0030900 |
302 |
0.030
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.029
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.029
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.029
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.029
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.029
|
Mouse |
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.029
|
Worm |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.029
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.029
|
Mouse |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.029
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.028
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.028
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.028
|
Mouse |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.028
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.028
|
Human |
|
|
associative learning
|
GO:0008306 |
61 |
0.028
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.028
|
Mouse |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.028
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.028
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.028
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.028
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.028
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
7 |
0.028
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.028
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.027
|
Mouse |
|
|
sensory perception
|
GO:0007600 |
245 |
0.027
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.027
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.027
|
Human Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.027
|
Worm Fly |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.027
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.027
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.027
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.027
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.027
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.027
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.027
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.027
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.026
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.026
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.026
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.026
|
|
|
|
protein export from nucleus
|
GO:0006611 |
20 |
0.026
|
Fly |
|
|
neuron migration
|
GO:0001764 |
122 |
0.026
|
Fly |
|
|
innate immune response
|
GO:0045087 |
157 |
0.026
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.026
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.026
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.026
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.026
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.025
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.025
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.025
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.025
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.025
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.025
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.025
|
|
|
|
male meiosis i
|
GO:0007141 |
16 |
0.025
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.025
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.025
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.025
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.025
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.024
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.024
|
Mouse |
|
|
positive regulation of apoptotic cell clearance
|
GO:2000427 |
3 |
0.024
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.024
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.024
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.024
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.024
|
Worm |
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.024
|
|
|
|
planar cell polarity pathway involved in axis elongation
|
GO:0003402 |
4 |
0.024
|
Fly |
|
|
feeding behavior
|
GO:0007631 |
62 |
0.024
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.024
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.024
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.024
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.024
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.024
|
Mouse Fly |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.024
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.024
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.023
|
Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.023
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.023
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.023
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.023
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.023
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.023
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.023
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.023
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.023
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.023
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.023
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.023
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.023
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.023
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
3 |
0.022
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.022
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.022
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.022
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.022
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.022
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.022
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.022
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.022
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.022
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.022
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.022
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.022
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.022
|
|
|
|
negative regulation of cell aging
|
GO:0090344 |
5 |
0.022
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.022
|
|
|
|
regulation of ovulation
|
GO:0060278 |
3 |
0.022
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.022
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.022
|
Mouse |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.021
|
|
