Mus musculus

32 known processes

Plscr3

phospholipid scramblase 3

(Aliases: 2210403O21Rik,X83310,2610037N06Rik,ESTM3)

Plscr3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 97 0.341
ras protein signal transduction GO:0007265 77 0.293
muscle cell differentiation GO:0042692 261 0.154
aromatic compound catabolic process GO:0019439 286 0.143
rho protein signal transduction GO:0007266 32 0.129
regulation of cellular amino acid metabolic process GO:0006521 5 0.124
nucleobase containing small molecule metabolic process GO:0055086 352 0.120
ribonucleoside metabolic process GO:0009119 245 0.119
nucleoside phosphate metabolic process GO:0006753 338 0.115
nucleotide metabolic process GO:0009117 332 0.106
purine ribonucleotide metabolic process GO:0009150 290 0.098
nucleoside metabolic process GO:0009116 246 0.094
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.093
regulation of cellular catabolic process GO:0031329 242 0.089
gtp metabolic process GO:0046039 144 0.086
cell adhesion GO:0007155 329 0.086
ribonucleotide metabolic process GO:0009259 291 0.083
purine nucleoside triphosphate metabolic process GO:0009144 226 0.081
nucleoside triphosphate metabolic process GO:0009141 230 0.080
cellular amine metabolic process GO:0044106 44 0.079
ribonucleoside triphosphate metabolic process GO:0009199 220 0.077
carbohydrate derivative catabolic process GO:1901136 231 0.077
purine containing compound metabolic process GO:0072521 311 0.076
nucleotide catabolic process GO:0009166 217 0.076
guanosine containing compound catabolic process GO:1901069 144 0.074
regulation of cell motility GO:2000145 236 0.074
gtp catabolic process GO:0006184 143 0.073
regulation of nucleoside metabolic process GO:0009118 130 0.072
wnt signaling pathway GO:0016055 188 0.071
ribose phosphate metabolic process GO:0019693 291 0.070
heterocycle catabolic process GO:0046700 280 0.068
nucleoside phosphate catabolic process GO:1901292 222 0.067
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.066
guanosine containing compound metabolic process GO:1901068 144 0.065
purine nucleotide metabolic process GO:0006163 302 0.064
glycosyl compound catabolic process GO:1901658 206 0.063
ribonucleoside catabolic process GO:0042454 206 0.061
regulation of purine nucleotide catabolic process GO:0033121 122 0.060
regulation of cellular ketone metabolic process GO:0010565 66 0.059
regulation of neuron differentiation GO:0045664 281 0.059
positive regulation of apoptotic process GO:0043065 217 0.058
Mouse
purine nucleotide catabolic process GO:0006195 211 0.058
regulation of protein localization GO:0032880 231 0.058
regulation of nucleotide catabolic process GO:0030811 122 0.057
regulation of organelle organization GO:0033043 289 0.056
peptidyl amino acid modification GO:0018193 336 0.055
nucleoside triphosphate catabolic process GO:0009143 205 0.055
response to oxidative stress GO:0006979 123 0.055
cellular amino acid metabolic process GO:0006520 103 0.054
Mouse
regulation of gtp catabolic process GO:0033124 113 0.053
purine ribonucleoside catabolic process GO:0046130 205 0.053
positive regulation of nervous system development GO:0051962 221 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
purine nucleoside metabolic process GO:0042278 241 0.051
purine nucleoside catabolic process GO:0006152 205 0.051
regulation of purine nucleotide metabolic process GO:1900542 169 0.050
positive regulation of cell death GO:0010942 224 0.049
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.048
purine ribonucleotide catabolic process GO:0009154 208 0.048
regulation of ras protein signal transduction GO:0046578 114 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.046
organonitrogen compound catabolic process GO:1901565 264 0.046
ribonucleotide catabolic process GO:0009261 208 0.045
mitochondrion organization GO:0007005 134 0.045
regulation of protein transport GO:0051223 163 0.045
amine metabolic process GO:0009308 45 0.043
cellular response to organonitrogen compound GO:0071417 145 0.042
regulation of secretion GO:0051046 274 0.042
positive regulation of cell development GO:0010720 237 0.041
purine ribonucleoside metabolic process GO:0046128 241 0.041
cellular ketone metabolic process GO:0042180 84 0.041
stem cell differentiation GO:0048863 268 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
intracellular protein transport GO:0006886 204 0.040
organic cyclic compound catabolic process GO:1901361 295 0.040
regulation of cell migration GO:0030334 219 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
canonical wnt signaling pathway GO:0060070 130 0.039
striated muscle cell development GO:0055002 125 0.038
regulation of hydrolase activity GO:0051336 246 0.037
negative regulation of phosphate metabolic process GO:0045936 184 0.037
positive regulation of gtp catabolic process GO:0033126 85 0.037
response to organonitrogen compound GO:0010243 246 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
transmembrane transport GO:0055085 412 0.035
membrane organization GO:0061024 245 0.035
Mouse
purine containing compound catabolic process GO:0072523 213 0.035
inflammatory response GO:0006954 244 0.035
Mouse
regulation of protein kinase activity GO:0045859 232 0.034
positive regulation of programmed cell death GO:0043068 218 0.034
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
cellular response to growth factor stimulus GO:0071363 197 0.032
regulation of wnt signaling pathway GO:0030111 123 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
Mouse
regulation of ras gtpase activity GO:0032318 88 0.031
axonogenesis GO:0007409 274 0.031
regulation of cell activation GO:0050865 289 0.031
mapk cascade GO:0000165 281 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
Mouse
organophosphate catabolic process GO:0046434 232 0.030
muscle tissue development GO:0060537 308 0.029
muscle fiber development GO:0048747 76 0.029
negative regulation of cell activation GO:0050866 111 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
negative regulation of molecular function GO:0044092 258 0.029
Mouse
positive regulation of protein modification process GO:0031401 299 0.028
negative regulation of phosphorylation GO:0042326 166 0.028
stem cell maintenance GO:0019827 130 0.028
protein targeting GO:0006605 143 0.027
endomembrane system organization GO:0010256 147 0.027
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.027
positive regulation of mapk cascade GO:0043410 170 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
nucleoside catabolic process GO:0009164 206 0.027
respiratory tube development GO:0030323 167 0.027
myotube differentiation GO:0014902 105 0.027
negative regulation of cellular component organization GO:0051129 194 0.026
microtubule cytoskeleton organization GO:0000226 157 0.026
regulation of kinase activity GO:0043549 249 0.026
leukocyte differentiation GO:0002521 342 0.026
muscle cell development GO:0055001 133 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.025
regulation of cellular response to stress GO:0080135 159 0.025
Mouse
regulation of lymphocyte activation GO:0051249 240 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
asymmetric neuroblast division GO:0055059 1 0.025
response to lipopolysaccharide GO:0032496 128 0.025
positive regulation of transferase activity GO:0051347 167 0.025
regulation of establishment of protein localization GO:0070201 181 0.024
cytokine production GO:0001816 319 0.024
compound eye development GO:0048749 1 0.024
cell substrate adhesion GO:0031589 130 0.024
immune effector process GO:0002252 321 0.024
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
regulation of multi organism process GO:0043900 111 0.024
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.024
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
regulation of cell adhesion GO:0030155 154 0.024
carbohydrate homeostasis GO:0033500 128 0.024
actin cytoskeleton organization GO:0030036 220 0.023
negative regulation of lymphocyte activation GO:0051250 91 0.023
regulation of cell projection organization GO:0031344 206 0.023
innate immune response GO:0045087 157 0.023
Mouse
regulation of intracellular transport GO:0032386 159 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
regulation of mapk cascade GO:0043408 248 0.023
regulation of transferase activity GO:0051338 263 0.022
apoptotic signaling pathway GO:0097190 306 0.022
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
regulation of ossification GO:0030278 112 0.022
cation transmembrane transport GO:0098655 266 0.022
positive regulation of gtpase activity GO:0043547 85 0.022
ossification GO:0001503 216 0.022
lung development GO:0030324 164 0.021
striated muscle tissue development GO:0014706 293 0.021
stem cell development GO:0048864 219 0.021
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
positive regulation of protein transport GO:0051222 93 0.021
regulation of rho gtpase activity GO:0032319 58 0.020
male gamete generation GO:0048232 285 0.020
protein localization to membrane GO:0072657 108 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
regulation of response to wounding GO:1903034 189 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
protein localization to nucleus GO:0034504 121 0.020
lipid transport GO:0006869 98 0.020
blood circulation GO:0008015 195 0.020
rac protein signal transduction GO:0016601 13 0.019
mitotic cell cycle process GO:1903047 159 0.019
regulation of osteoblast differentiation GO:0045667 67 0.019
negative regulation of t cell activation GO:0050868 65 0.019
negative regulation of nervous system development GO:0051961 156 0.019
circadian rhythm GO:0007623 114 0.019
neural precursor cell proliferation GO:0061351 121 0.019
forebrain development GO:0030900 302 0.019
regulation of cytokine production GO:0001817 266 0.019
negative regulation of protein modification process GO:0031400 163 0.019
protein import into nucleus GO:0006606 95 0.018
developmental maturation GO:0021700 193 0.018
cell matrix adhesion GO:0007160 68 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
skeletal muscle fiber development GO:0048741 58 0.018
cellular protein catabolic process GO:0044257 155 0.018
epithelial cell development GO:0002064 159 0.018
skeletal muscle organ development GO:0060538 163 0.018
protein maturation GO:0051604 176 0.018
negative regulation of organelle organization GO:0010639 90 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.018
neural tube development GO:0021915 160 0.018
stem cell proliferation GO:0072089 117 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.018
positive regulation of ras gtpase activity GO:0032320 65 0.018
regulation of membrane potential GO:0042391 192 0.018
response to insulin GO:0032868 100 0.018
dna metabolic process GO:0006259 303 0.018
plasma membrane organization GO:0007009 90 0.018
Mouse
response to inorganic substance GO:0010035 96 0.018
negative regulation of kinase activity GO:0033673 81 0.018
b cell activation GO:0042113 161 0.018
regulation of secretion by cell GO:1903530 249 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
positive regulation of defense response GO:0031349 124 0.017
Mouse
nuclear transport GO:0051169 139 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
interspecies interaction between organisms GO:0044419 83 0.017
Mouse
sensory perception GO:0007600 245 0.017
response to peptide hormone GO:0043434 127 0.017
regulation of organ morphogenesis GO:2000027 144 0.017
protein localization to organelle GO:0033365 185 0.017
negative regulation of immune system process GO:0002683 209 0.017
cellular response to organic cyclic compound GO:0071407 87 0.017
dendrite development GO:0016358 115 0.017
cytoplasmic transport GO:0016482 234 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
macromolecule catabolic process GO:0009057 281 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
adult behavior GO:0030534 135 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
antigen receptor mediated signaling pathway GO:0050851 64 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
Mouse
regulation of defense response GO:0031347 233 0.016
Mouse
gland development GO:0048732 330 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
epidermis development GO:0008544 187 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.016
synapse organization GO:0050808 125 0.016
glycerolipid biosynthetic process GO:0045017 50 0.016
Mouse
regulation of intracellular protein transport GO:0033157 82 0.016
cell fate commitment GO:0045165 210 0.016
protein processing GO:0016485 163 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
skeletal system development GO:0001501 356 0.015
cell cell junction organization GO:0045216 72 0.015
renal system development GO:0072001 225 0.015
learning or memory GO:0007611 148 0.015
carbohydrate metabolic process GO:0005975 230 0.015
lipid localization GO:0010876 126 0.015
cognition GO:0050890 149 0.015
cellular response to lipid GO:0071396 145 0.015
response to oxygen levels GO:0070482 62 0.015
ear development GO:0043583 200 0.015
regulation of canonical wnt signaling pathway GO:0060828 82 0.015
chemotaxis GO:0006935 247 0.015
maintenance of location GO:0051235 89 0.015
negative regulation of phagocytosis GO:0050765 4 0.014
mitotic cell cycle GO:0000278 195 0.014
regulation of cellular component size GO:0032535 121 0.014
cellular response to oxidative stress GO:0034599 76 0.014
wound healing GO:0042060 157 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
regulation of cell cycle GO:0051726 281 0.014
asymmetric stem cell division GO:0098722 3 0.014
leukocyte mediated immunity GO:0002443 174 0.014
establishment of protein localization to membrane GO:0090150 54 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
locomotory behavior GO:0007626 195 0.014
phospholipid metabolic process GO:0006644 87 0.014
Mouse
response to light stimulus GO:0009416 135 0.014
respiratory system development GO:0060541 190 0.014
establishment of protein localization to plasma membrane GO:0090002 34 0.014
single organism nuclear import GO:1902593 95 0.014
glial cell differentiation GO:0010001 131 0.014
regulation of innate immune response GO:0045088 91 0.014
Mouse
blood vessel morphogenesis GO:0048514 285 0.014
multicellular organismal signaling GO:0035637 91 0.014
cerebellar granule cell precursor tangential migration GO:0021935 1 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
regulation of rho protein signal transduction GO:0035023 71 0.013
actin filament organization GO:0007015 113 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
negative regulation of wnt signaling pathway GO:0030178 73 0.013
nitrogen compound transport GO:0071705 271 0.013
regulation of myotube differentiation GO:0010830 62 0.013
response to acid chemical GO:0001101 111 0.013
cellular response to acid chemical GO:0071229 68 0.013
regulation of neuron projection development GO:0010975 169 0.013
protein secretion GO:0009306 111 0.013
activation of immune response GO:0002253 138 0.013
regulation of map kinase activity GO:0043405 120 0.013
cellular homeostasis GO:0019725 240 0.013
regulation of ion transport GO:0043269 215 0.013
rab protein signal transduction GO:0032482 1 0.013
protein ubiquitination GO:0016567 171 0.013
regulation of protein secretion GO:0050708 82 0.013
cell type specific apoptotic process GO:0097285 268 0.013
response to organic cyclic compound GO:0014070 198 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
Mouse
regulation of cell cycle process GO:0010564 160 0.013
ion transmembrane transport GO:0034220 361 0.013
epithelial cell proliferation GO:0050673 174 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
protein catabolic process GO:0030163 221 0.012
response to radiation GO:0009314 165 0.012
peptidyl serine modification GO:0018209 83 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
smoothened signaling pathway GO:0007224 105 0.012
negative regulation of transferase activity GO:0051348 85 0.012
microtubule based process GO:0007017 236 0.012
cation transport GO:0006812 399 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
response to extracellular stimulus GO:0009991 127 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
glycoprotein metabolic process GO:0009100 116 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
regulation of protein catabolic process GO:0042176 108 0.012
cellular lipid metabolic process GO:0044255 323 0.012
Mouse
modification dependent protein catabolic process GO:0019941 133 0.012
positive regulation of organelle organization GO:0010638 128 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
anion transmembrane transport GO:0098656 71 0.012
regulation of proteolysis GO:0030162 164 0.012
spermatogenesis GO:0007283 284 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
cell junction organization GO:0034330 77 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
neuron projection guidance GO:0097485 141 0.012
regulation of hormone levels GO:0010817 211 0.012
peptidyl lysine modification GO:0018205 77 0.012
positive regulation of kinase activity GO:0033674 155 0.012
chromatin organization GO:0006325 206 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
Mouse
response to peptide GO:1901652 136 0.012
chromatin modification GO:0016568 187 0.012
lateral inhibition GO:0046331 1 0.012
homeostasis of number of cells GO:0048872 210 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
regulation of system process GO:0044057 200 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
organelle localization GO:0051640 179 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
immunoglobulin production GO:0002377 73 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.012
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.012
positive regulation of cell migration GO:0030335 109 0.012
digestive tract development GO:0048565 190 0.012
atp metabolic process GO:0046034 75 0.011
cellular response to peptide GO:1901653 92 0.011
central nervous system neuron development GO:0021954 67 0.011
response to interferon gamma GO:0034341 34 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
Mouse
organelle fission GO:0048285 170 0.011
nuclear division GO:0000280 158 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
digestive system development GO:0055123 200 0.011
mitochondrion distribution GO:0048311 4 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
Mouse
focal adhesion assembly GO:0048041 19 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.011
cellularization GO:0007349 1 0.011
regulation of actin filament based process GO:0032970 99 0.011
development of primary sexual characteristics GO:0045137 143 0.011
response to growth factor GO:0070848 198 0.011
anion transport GO:0006820 177 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
gene silencing by mirna GO:0035195 10 0.011
transmission of nerve impulse GO:0019226 76 0.011
myotube cell development GO:0014904 60 0.011
regulation of protein targeting GO:1903533 61 0.011
mesenchymal cell development GO:0014031 93 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
peptide transport GO:0015833 133 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
synaptic transmission GO:0007268 329 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
extracellular matrix organization GO:0030198 147 0.011
protein localization to plasma membrane GO:0072659 57 0.011
establishment of planar polarity GO:0001736 28 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
protein import GO:0017038 101 0.011
endocytosis GO:0006897 168 0.011
leukocyte activation involved in immune response GO:0002366 126 0.010
regulation of inflammatory response GO:0050727 147 0.010
glucose homeostasis GO:0042593 128 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.010
positive regulation of cell motility GO:2000147 116 0.010
mesenchymal cell differentiation GO:0048762 107 0.010
neuronal action potential GO:0019228 54 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
regulation of t cell activation GO:0050863 170 0.010
neuron death GO:0070997 154 0.010
negative regulation of leukocyte differentiation GO:1902106 51 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
amide transport GO:0042886 138 0.010
regulation of muscle tissue development GO:1901861 97 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
regulation of protein binding GO:0043393 60 0.010
Mouse

Plscr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.012