|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.664
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.542
|
Mouse |
|
|
action potential
|
GO:0001508 |
78 |
0.442
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.435
|
Mouse Fly |
|
|
organic anion transport
|
GO:0015711 |
137 |
0.381
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.321
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.288
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.277
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.270
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.259
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.252
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.238
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.238
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.233
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.220
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.214
|
Mouse Fly |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.213
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.206
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.203
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.196
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.193
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.192
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.188
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.178
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.176
|
Mouse Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.174
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.172
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.163
|
Fly |
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.162
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.160
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.157
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.151
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.147
|
Mouse Fly |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.146
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.143
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.135
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.135
|
|
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.134
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.128
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.126
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.125
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.123
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.120
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.120
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.119
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.117
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.114
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.114
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.114
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.113
|
Fly |
|
|
fast calcium ion dependent exocytosis of neurotransmitter
|
GO:0098746 |
1 |
0.113
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.112
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.112
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.110
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.110
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.109
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.109
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.107
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.107
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.107
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.105
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.104
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.103
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.101
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.100
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.100
|
Mouse Fly |
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.099
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.099
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.098
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.097
|
Mouse |
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.096
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.094
|
Mouse Fly |
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.094
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.094
|
Mouse |
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.093
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.093
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.092
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.091
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.091
|
Worm |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.090
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.089
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.089
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.088
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.086
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.085
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.085
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.085
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.084
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.084
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.083
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.082
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.081
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.081
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.080
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.079
|
Fly |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.079
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.078
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.077
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.076
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.075
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.075
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.075
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.073
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.073
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.073
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.073
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.072
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.072
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.071
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.070
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.068
|
Mouse Fly |
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.068
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.068
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.068
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.067
|
Fly |
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.067
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.067
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.066
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.065
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.065
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.065
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.065
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.064
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.064
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.064
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.063
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.063
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.062
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.061
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.061
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.061
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.060
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.060
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.060
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.059
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.059
|
Fly |
|
|
cytokine production
|
GO:0001816 |
319 |
0.059
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.059
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.058
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.058
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.058
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.057
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.057
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.057
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.056
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
71 |
0.056
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.056
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.056
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.056
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.055
|
|
|
|
l alpha amino acid transmembrane transport
|
GO:1902475 |
23 |
0.055
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.053
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.053
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.052
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.052
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.052
|
Mouse Fly |
|
|
response to peptide
|
GO:1901652 |
136 |
0.051
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.051
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.051
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.051
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.051
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.050
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.050
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.049
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.049
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.049
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.049
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.048
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.048
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.048
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.046
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.046
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.045
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.045
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.045
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.045
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.044
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.044
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.044
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.044
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.044
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.043
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.043
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.043
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.043
|
Mouse Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.043
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.043
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.043
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.042
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.042
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.042
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.041
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.041
|
|
|
|
general adaptation syndrome
|
GO:0051866 |
2 |
0.041
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.040
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.040
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.040
|
|
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.039
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.039
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.039
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.039
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.039
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.039
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.039
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.039
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.039
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.038
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.038
|
|
|
|
metanephric mesenchymal cell migration
|
GO:0035789 |
2 |
0.038
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.038
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
16 |
0.038
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.038
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.038
|
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.037
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.037
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.037
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.037
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.037
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.037
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.037
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.037
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.037
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.036
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.036
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.036
|
|
|
|
potassium ion homeostasis
|
GO:0055075 |
4 |
0.036
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.036
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.036
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.036
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.036
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.035
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.035
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.035
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.035
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.035
|
|
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.035
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.035
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.034
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.034
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.034
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.034
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.034
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.034
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.034
|
|
|
|
learning
|
GO:0007612 |
98 |
0.034
|
Fly |
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.034
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.034
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.034
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.033
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.033
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.033
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.033
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.033
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.033
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.033
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.033
|
Fly |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.032
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.032
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.032
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.032
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.032
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.032
|
Mouse Fly |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.032
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.032
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.031
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.031
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.031
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.031
|
|
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
3 |
0.031
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.031
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.031
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.030
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.030
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.030
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.030
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.030
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.030
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.030
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.030
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.030
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.030
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.030
|
|
|
|
dopamine metabolic process
|
GO:0042417 |
23 |
0.030
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.029
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.029
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.029
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.029
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.029
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.029
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.029
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.029
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.029
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.029
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.029
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.029
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.029
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.029
|
Worm |
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.029
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.028
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
15 |
0.028
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.028
|
|
|
|
water homeostasis
|
GO:0030104 |
27 |
0.028
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.028
|
|
|
|
optic nerve structural organization
|
GO:0021633 |
2 |
0.028
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.028
|
|
|
|
cellular response to temperature stimulus
|
GO:0071502 |
2 |
0.028
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.027
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.027
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.027
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
22 |
0.027
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.027
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.027
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.027
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.027
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.027
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.027
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.026
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.026
|
|
|
|
protein localization to juxtaparanode region of axon
|
GO:0071205 |
4 |
0.026
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.026
|
|
|
|
relaxation of smooth muscle
|
GO:0044557 |
8 |
0.026
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.026
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.026
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.026
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.026
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.026
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.026
|
|
|
|
negative regulation of heart rate
|
GO:0010459 |
4 |
0.025
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.025
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.025
|
Worm |
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.025
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.025
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.025
|
Fly |
|
|
negative regulation of hormone biosynthetic process
|
GO:0032353 |
4 |
0.025
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.025
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.025
|
|
|
|
plasma membrane repair
|
GO:0001778 |
7 |
0.025
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.025
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.025
|
|
|
|
glycine transport
|
GO:0015816 |
4 |
0.025
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.024
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.024
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.024
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
18 |
0.024
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.024
|
|
|
|
calcium ion dependent exocytosis of neurotransmitter
|
GO:0048791 |
7 |
0.024
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.024
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.024
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.024
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.024
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.024
|
|
|
|
vasodilation
|
GO:0042311 |
28 |
0.024
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.024
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.024
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.024
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.024
|
Mouse Fly |
|
|
acrosome reaction
|
GO:0007340 |
19 |
0.024
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.023
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.023
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.023
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.023
|
Mouse |
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.023
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.023
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.023
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.023
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.023
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.023
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.023
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.023
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.023
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.023
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.022
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.022
|
|
|
|
amino acid transmembrane transport
|
GO:0003333 |
37 |
0.022
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.022
|
|
|
|
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010579 |
3 |
0.022
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.022
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.022
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.022
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.022
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.022
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
3 |
0.022
|
|
|
|
gonad morphogenesis
|
GO:0035262 |
1 |
0.022
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.022
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.022
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.022
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.021
|
|
|
|
serotonin metabolic process
|
GO:0042428 |
8 |
0.021
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.021
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.021
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
3 |
0.021
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.021
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.021
|
|
|
|
negative regulation of potassium ion transport
|
GO:0043267 |
7 |
0.021
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.021
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.021
|
|
|
|
mating behavior sex discrimination
|
GO:0048047 |
1 |
0.021
|
|
|
|
cellular response to histamine
|
GO:0071420 |
1 |
0.021
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.021
|
|
|
|
response to cocaine
|
GO:0042220 |
14 |
0.021
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.020
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.020
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.020
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.020
|
Mouse Fly |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.020
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.020
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.020
|
|
|
|
prevention of polyspermy
|
GO:0060468 |
4 |
0.020
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.020
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.020
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.020
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.020
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.020
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.020
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.020
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.020
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.020
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.020
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.020
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.020
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.020
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.020
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.020
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.020
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
35 |
0.020
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.020
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.020
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.020
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.019
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.019
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.019
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.019
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.019
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.019
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.019
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.019
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.019
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.019
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
54 |
0.019
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.019
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.019
|
|
|
|
synaptic transmission glycinergic
|
GO:0060012 |
2 |
0.019
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.019
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.019
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.019
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.019
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.019
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.019
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.019
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.019
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.019
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.019
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.019
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.019
|
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
51 |
0.018
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.018
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.018
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.018
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.018
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.018
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.018
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.018
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.018
|
|
|
|
negative regulation of behavior
|
GO:0048521 |
14 |
0.018
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.018
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.018
|
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
2 |
0.018
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.018
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.018
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.018
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.018
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.018
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.018
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.018
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.018
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.018
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.018
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.018
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.018
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.017
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.017
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.017
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.017
|
|
|
|
l glutamate import into cell
|
GO:1990123 |
3 |
0.017
|
|
|
|
negative regulation of smooth muscle contraction
|
GO:0045986 |
10 |
0.017
|
|
|
|
glycolipid biosynthetic process
|
GO:0009247 |
13 |
0.017
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.017
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.017
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
32 |
0.017
|
|
|
|
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010578 |
3 |
0.017
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.017
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.017
|
|
