Mus musculus

251 known processes

Serpine2

serine (or cysteine) peptidase inhibitor, clade E, member 2

(Aliases: PI-7,Spi4,PN-1,B230326M24Rik,PAI-1,PI7)

Serpine2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neuron differentiation GO:0045664 281 0.232
Rat
negative regulation of molecular function GO:0044092 258 0.191
response to growth factor GO:0070848 198 0.181
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.150
cellular response to growth factor stimulus GO:0071363 197 0.131
Mouse
regulation of cell motility GO:2000145 236 0.121
regulation of hydrolase activity GO:0051336 246 0.121
skeletal system development GO:0001501 356 0.115
cartilage development GO:0051216 140 0.112
respiratory system development GO:0060541 190 0.111
ribonucleotide metabolic process GO:0009259 291 0.090
nucleobase containing small molecule metabolic process GO:0055086 352 0.088
extracellular matrix organization GO:0030198 147 0.086
mitotic cell cycle GO:0000278 195 0.083
purine nucleotide metabolic process GO:0006163 302 0.083
extracellular structure organization GO:0043062 148 0.082
ribose phosphate metabolic process GO:0019693 291 0.075
cellular amine metabolic process GO:0044106 44 0.074
ossification GO:0001503 216 0.073
protein maturation GO:0051604 176 0.071
regulation of cellular amine metabolic process GO:0033238 20 0.071
amine metabolic process GO:0009308 45 0.070
negative regulation of cell proliferation GO:0008285 296 0.069
nucleoside phosphate metabolic process GO:0006753 338 0.067
cellular ketone metabolic process GO:0042180 84 0.066
purine containing compound metabolic process GO:0072521 311 0.066
regulation of peptidase activity GO:0052547 96 0.066
regulation of proteolysis GO:0030162 164 0.065
regulation of cell migration GO:0030334 219 0.065
blood vessel morphogenesis GO:0048514 285 0.065
Mouse
positive regulation of programmed cell death GO:0043068 218 0.064
regulation of transferase activity GO:0051338 263 0.064
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.063
positive regulation of protein modification process GO:0031401 299 0.063
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
intracellular protein transport GO:0006886 204 0.062
regionalization GO:0003002 337 0.062
negative regulation of cellular component organization GO:0051129 194 0.061
negative regulation of protein metabolic process GO:0051248 282 0.060
regulation of cell cycle GO:0051726 281 0.060
regulation of mapk cascade GO:0043408 248 0.060
response to oxidative stress GO:0006979 123 0.059
connective tissue development GO:0061448 179 0.057
response to radiation GO:0009314 165 0.057
Rat
nucleoside catabolic process GO:0009164 206 0.057
protein catabolic process GO:0030163 221 0.057
skeletal system morphogenesis GO:0048705 203 0.056
positive regulation of cell death GO:0010942 224 0.056
transmembrane transport GO:0055085 412 0.055
chondrocyte differentiation GO:0002062 72 0.055
positive regulation of cell development GO:0010720 237 0.055
Human Rat
single organism cell adhesion GO:0098602 156 0.054
regulation of cytokine production GO:0001817 266 0.054
organonitrogen compound catabolic process GO:1901565 264 0.054
response to transforming growth factor beta GO:0071559 88 0.053
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
peptidyl amino acid modification GO:0018193 336 0.052
fertilization GO:0009566 127 0.052
cellular amino acid metabolic process GO:0006520 103 0.051
learning or memory GO:0007611 148 0.050
purine ribonucleotide catabolic process GO:0009154 208 0.050
transmission of nerve impulse GO:0019226 76 0.049
ribonucleoside metabolic process GO:0009119 245 0.049
protein processing GO:0016485 163 0.049
nucleotide catabolic process GO:0009166 217 0.049
spermatogenesis GO:0007283 284 0.048
nucleotide metabolic process GO:0009117 332 0.048
positive regulation of protein phosphorylation GO:0001934 242 0.048
regulation of cellular ketone metabolic process GO:0010565 66 0.047
regulation of protein kinase activity GO:0045859 232 0.047
response to organonitrogen compound GO:0010243 246 0.046
positive regulation of nervous system development GO:0051962 221 0.046
Human Rat
organonitrogen compound biosynthetic process GO:1901566 192 0.046
chemotaxis GO:0006935 247 0.046
dna metabolic process GO:0006259 303 0.045
gland development GO:0048732 330 0.045
respiratory tube development GO:0030323 167 0.045
action potential GO:0001508 78 0.045
ribonucleoside triphosphate catabolic process GO:0009203 199 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
axonogenesis GO:0007409 274 0.044
regulation of endopeptidase activity GO:0052548 89 0.043
negative regulation of cell cycle GO:0045786 123 0.043
positive regulation of cell motility GO:2000147 116 0.043
developmental growth involved in morphogenesis GO:0060560 138 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.042
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.042
macromolecule catabolic process GO:0009057 281 0.040
nucleoside metabolic process GO:0009116 246 0.040
stem cell development GO:0048864 219 0.039
forebrain development GO:0030900 302 0.039
negative regulation of immune system process GO:0002683 209 0.039
positive regulation of cell migration GO:0030335 109 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.038
purine nucleotide catabolic process GO:0006195 211 0.038
leukocyte migration GO:0050900 124 0.038
synaptic transmission GO:0007268 329 0.038
ribonucleoside catabolic process GO:0042454 206 0.038
regulation of system process GO:0044057 200 0.038
camera type eye development GO:0043010 266 0.037
positive regulation of cell projection organization GO:0031346 95 0.037
Rat
mitotic cell cycle process GO:1903047 159 0.037
central nervous system neuron differentiation GO:0021953 162 0.037
muscle system process GO:0003012 141 0.037
ameboidal type cell migration GO:0001667 128 0.037
regulation of neuron projection development GO:0010975 169 0.037
Rat
cell fate commitment GO:0045165 210 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
regulation of organelle organization GO:0033043 289 0.036
positive regulation of secretion GO:0051047 130 0.036
purine ribonucleoside catabolic process GO:0046130 205 0.036
response to organic cyclic compound GO:0014070 198 0.036
telencephalon development GO:0021537 186 0.035
regulation of apoptotic signaling pathway GO:2001233 197 0.035
cell adhesion GO:0007155 329 0.035
neuronal action potential GO:0019228 54 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
associative learning GO:0008306 61 0.035
carbohydrate derivative biosynthetic process GO:1901137 183 0.035
wnt signaling pathway GO:0016055 188 0.034
neuron projection guidance GO:0097485 141 0.034
heart morphogenesis GO:0003007 178 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
regulation of cellular response to stress GO:0080135 159 0.034
single fertilization GO:0007338 82 0.034
regulation of kinase activity GO:0043549 249 0.034
cellular lipid metabolic process GO:0044255 323 0.034
regulation of membrane potential GO:0042391 192 0.034
multi multicellular organism process GO:0044706 109 0.034
cellular response to dna damage stimulus GO:0006974 207 0.034
glycoprotein metabolic process GO:0009100 116 0.033
regulation of mitotic cell cycle GO:0007346 126 0.033
leukocyte proliferation GO:0070661 172 0.033
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
positive regulation of transferase activity GO:0051347 167 0.032
multicellular organism growth GO:0035264 161 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
regulation of cellular component biogenesis GO:0044087 181 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
regulation of secretion GO:0051046 274 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
regulation of cell projection organization GO:0031344 206 0.031
Rat
epithelial cell proliferation GO:0050673 174 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
positive regulation of proteolysis GO:0045862 85 0.031
regulation of neuron death GO:1901214 134 0.031
negative regulation of protein maturation GO:1903318 79 0.031
sensory system development GO:0048880 3 0.031
male gamete generation GO:0048232 285 0.031
regulation of cellular response to growth factor stimulus GO:0090287 82 0.031
cell type specific apoptotic process GO:0097285 268 0.031
single organismal cell cell adhesion GO:0016337 131 0.031
apoptotic signaling pathway GO:0097190 306 0.031
reactive oxygen species metabolic process GO:0072593 84 0.030
inflammatory response GO:0006954 244 0.030
myelination GO:0042552 74 0.030
cation transport GO:0006812 399 0.030
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.030
Mouse
negative regulation of cell development GO:0010721 169 0.030
regulation of protein maturation GO:1903317 96 0.030
fat cell differentiation GO:0045444 160 0.030
aromatic compound catabolic process GO:0019439 286 0.029
blood circulation GO:0008015 195 0.029
developmental maturation GO:0021700 193 0.029
olfactory learning GO:0008355 2 0.029
cytokine production GO:0001816 319 0.029
regulation of wnt signaling pathway GO:0030111 123 0.029
cellular response to oxidative stress GO:0034599 76 0.029
nuclear division GO:0000280 158 0.029
multicellular organismal homeostasis GO:0048871 164 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.028
cell chemotaxis GO:0060326 81 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
regulation of neuron apoptotic process GO:0043523 122 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
negative regulation of hydrolase activity GO:0051346 71 0.028
coagulation GO:0050817 78 0.028
urogenital system development GO:0001655 261 0.028
protein localization to organelle GO:0033365 185 0.028
response to light stimulus GO:0009416 135 0.028
rhythmic process GO:0048511 174 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
cellular protein catabolic process GO:0044257 155 0.027
neural tube development GO:0021915 160 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
neuron death GO:0070997 154 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
defense response to bacterium GO:0042742 119 0.027
Mouse
organophosphate catabolic process GO:0046434 232 0.027
cognition GO:0050890 149 0.027
glial cell differentiation GO:0010001 131 0.027
Human
stem cell differentiation GO:0048863 268 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
muscle tissue development GO:0060537 308 0.026
regulation of reproductive process GO:2000241 66 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
metanephros development GO:0001656 79 0.026
regulation of cell cycle process GO:0010564 160 0.026
b cell activation GO:0042113 161 0.026
exocytosis GO:0006887 121 0.026
cellular response to lipid GO:0071396 145 0.025
sensory organ morphogenesis GO:0090596 242 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
tissue remodeling GO:0048771 102 0.025
nuclear transport GO:0051169 139 0.025
axon ensheathment GO:0008366 76 0.025
actin cytoskeleton organization GO:0030036 220 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
regulation of hormone levels GO:0010817 211 0.025
regulation of protein processing GO:0070613 96 0.025
negative regulation of protein processing GO:0010955 79 0.025
neurotransmitter transport GO:0006836 76 0.025
regulation of secretion by cell GO:1903530 249 0.025
ensheathment of neurons GO:0007272 76 0.025
sequestering of calcium ion GO:0051208 18 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
long term synaptic potentiation GO:0060291 25 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
germ cell development GO:0007281 185 0.024
multicellular organismal signaling GO:0035637 91 0.024
membrane organization GO:0061024 245 0.024
pallium development GO:0021543 120 0.024
regulation of neurotransmitter levels GO:0001505 87 0.024
sensory perception GO:0007600 245 0.024
response to hypoxia GO:0001666 58 0.024
striated muscle tissue development GO:0014706 293 0.024
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.024
regulation of ion transport GO:0043269 215 0.023
cell growth GO:0016049 130 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
regulation of multi organism process GO:0043900 111 0.023
cyclic nucleotide metabolic process GO:0009187 59 0.023
lung development GO:0030324 164 0.023
mesonephros development GO:0001823 97 0.023
response to oxygen levels GO:0070482 62 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
response to inorganic substance GO:0010035 96 0.023
negative regulation of neuron differentiation GO:0045665 101 0.023
divalent metal ion transport GO:0070838 172 0.023
metal ion homeostasis GO:0055065 189 0.022
regulation of organ morphogenesis GO:2000027 144 0.022
learning GO:0007612 98 0.022
negative regulation of nervous system development GO:0051961 156 0.022
digestive system development GO:0055123 200 0.022
neuron apoptotic process GO:0051402 142 0.022
negative regulation of neuron death GO:1901215 98 0.022
cytoplasmic transport GO:0016482 234 0.022
renal system development GO:0072001 225 0.022
mesonephric tubule development GO:0072164 94 0.022
divalent inorganic cation transport GO:0072511 178 0.022
epithelium migration GO:0090132 63 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
heterocycle catabolic process GO:0046700 280 0.021
cation transmembrane transport GO:0098655 266 0.021
organelle localization GO:0051640 179 0.021
cerebellum development GO:0021549 77 0.021
epithelial cell migration GO:0010631 63 0.021
negative regulation of endopeptidase activity GO:0010951 44 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
regulation of intracellular transport GO:0032386 159 0.021
oligodendrocyte differentiation GO:0048709 53 0.021
cellular protein complex assembly GO:0043623 116 0.021
ureteric bud development GO:0001657 94 0.021
anatomical structure homeostasis GO:0060249 145 0.020
cardiac muscle tissue development GO:0048738 130 0.020
axon guidance GO:0007411 141 0.020
response to fibroblast growth factor GO:0071774 47 0.020
organ growth GO:0035265 117 0.020
regulation of cell activation GO:0050865 289 0.020
dna repair GO:0006281 107 0.020
dendrite development GO:0016358 115 0.020
embryonic epithelial tube formation GO:0001838 130 0.020
meiotic cell cycle GO:0051321 122 0.020
cellular chemical homeostasis GO:0055082 215 0.020
chromatin organization GO:0006325 206 0.020
mapk cascade GO:0000165 281 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
morphogenesis of a branching structure GO:0001763 203 0.020
cellular ion homeostasis GO:0006873 165 0.020
positive regulation of cell adhesion GO:0045785 80 0.019
homeostasis of number of cells GO:0048872 210 0.019
negative regulation of lymphocyte activation GO:0051250 91 0.019
proteoglycan metabolic process GO:0006029 38 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
bone development GO:0060348 120 0.019
peripheral nervous system neuron axonogenesis GO:0048936 3 0.019
negative regulation of peptidase activity GO:0010466 46 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
ion transmembrane transport GO:0034220 361 0.019
cardiac chamber development GO:0003205 108 0.019
purine containing compound catabolic process GO:0072523 213 0.019
myeloid cell differentiation GO:0030099 233 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
anion transport GO:0006820 177 0.019
negative regulation of epithelial cell proliferation GO:0050680 64 0.019
circadian rhythm GO:0007623 114 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
production of molecular mediator of immune response GO:0002440 103 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
calcium ion homeostasis GO:0055074 127 0.019
multicellular organismal response to stress GO:0033555 62 0.019
regulation of body fluid levels GO:0050878 162 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
cell recognition GO:0008037 83 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
nephron tubule development GO:0072080 84 0.018
endocytosis GO:0006897 168 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
Rat
multicellular organismal macromolecule metabolic process GO:0044259 19 0.018
regulation of chemotaxis GO:0050920 53 0.018
purine ribonucleotide biosynthetic process GO:0009152 59 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
protein localization to nucleus GO:0034504 121 0.018
muscle cell differentiation GO:0042692 261 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
maintenance of location GO:0051235 89 0.018
regulation of defense response GO:0031347 233 0.018
spermatid development GO:0007286 108 0.018
organophosphate biosynthetic process GO:0090407 122 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
gliogenesis GO:0042063 141 0.017
Human
carboxylic acid transport GO:0046942 100 0.017
g1 s transition of mitotic cell cycle GO:0000082 57 0.017
nuclear import GO:0051170 95 0.017
immune effector process GO:0002252 321 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
wound healing GO:0042060 157 0.017
blood coagulation GO:0007596 76 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
mesonephric epithelium development GO:0072163 94 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
retina development in camera type eye GO:0060041 119 0.017
regulation of homeostatic process GO:0032844 182 0.017
cell cycle g1 s phase transition GO:0044843 57 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
multi organism behavior GO:0051705 62 0.017
stem cell proliferation GO:0072089 117 0.017
response to peptide GO:1901652 136 0.017
mesoderm development GO:0007498 100 0.017
response to reactive oxygen species GO:0000302 56 0.017
regulation of map kinase activity GO:0043405 120 0.017
neuron migration GO:0001764 122 0.016
negative regulation of proteolysis GO:0045861 74 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
multicellular organismal metabolic process GO:0044236 28 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
single organism nuclear import GO:1902593 95 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
protein import into nucleus GO:0006606 95 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
myosin filament assembly GO:0031034 2 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.016
microtubule based process GO:0007017 236 0.016
meiotic nuclear division GO:0007126 115 0.016
skeletal muscle organ development GO:0060538 163 0.016
midgut development GO:0007494 4 0.016
regulation of binding GO:0051098 111 0.016
regulation of response to wounding GO:1903034 189 0.016
endomembrane system organization GO:0010256 147 0.016
cell division GO:0051301 120 0.016
myeloid leukocyte migration GO:0097529 57 0.016
sequestering of metal ion GO:0051238 19 0.016
hemostasis GO:0007599 78 0.016
positive regulation of cell activation GO:0050867 158 0.016
protein ubiquitination GO:0016567 171 0.016
negative regulation of growth GO:0045926 99 0.015
locomotory behavior GO:0007626 195 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
cardiac chamber morphogenesis GO:0003206 93 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
protein targeting GO:0006605 143 0.015
regulation of protein localization GO:0032880 231 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of organ growth GO:0046620 61 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
muscle cell development GO:0055001 133 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
visual learning GO:0008542 44 0.015
muscle contraction GO:0006936 101 0.015
epithelial cell development GO:0002064 159 0.015
striated muscle myosin thick filament assembly GO:0071688 1 0.015
response to insulin GO:0032868 100 0.015
bmp signaling pathway GO:0030509 93 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
trabecula morphogenesis GO:0061383 40 0.015
regulation of anatomical structure size GO:0090066 178 0.015
lipid localization GO:0010876 126 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
digestive tract development GO:0048565 190 0.015
negative regulation of cell migration GO:0030336 59 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
cellular response to abiotic stimulus GO:0071214 56 0.014
regulation of protein catabolic process GO:0042176 108 0.014
calcium ion transport GO:0006816 159 0.014
immune response activating signal transduction GO:0002757 116 0.014
acetylcholine transport GO:0015870 2 0.014
regulation of transmembrane transport GO:0034762 128 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
hormone metabolic process GO:0042445 86 0.014
cellular homeostasis GO:0019725 240 0.014
embryonic skeletal system development GO:0048706 120 0.014
cell substrate adhesion GO:0031589 130 0.014
carbohydrate metabolic process GO:0005975 230 0.014
t cell activation GO:0042110 289 0.014
neural precursor cell proliferation GO:0061351 121 0.014
mucopolysaccharide metabolic process GO:1903510 25 0.014
response to peptide hormone GO:0043434 127 0.014
inter male aggressive behavior GO:0002121 3 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
glucose homeostasis GO:0042593 128 0.014
b cell differentiation GO:0030183 78 0.014
nitrogen compound transport GO:0071705 271 0.014
acetylcholine secretion neurotransmission GO:0014055 2 0.014
organelle assembly GO:0070925 177 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
cation homeostasis GO:0055080 212 0.014
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.014
positive regulation of cell cycle GO:0045787 92 0.014
smoothened signaling pathway GO:0007224 105 0.014
detection of external stimulus GO:0009581 61 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
negative regulation of neuron projection development GO:0010977 50 0.013
metencephalon development GO:0022037 89 0.013
tube formation GO:0035148 140 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
striated muscle cell development GO:0055002 125 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
heart contraction GO:0060047 93 0.013
lateral inhibition GO:0046331 1 0.013
embryonic skeletal system morphogenesis GO:0048704 91 0.013
lymphocyte proliferation GO:0046651 164 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
organelle fission GO:0048285 170 0.013
response to lipopolysaccharide GO:0032496 128 0.013
collagen metabolic process GO:0032963 17 0.013
response to acid chemical GO:0001101 111 0.013
segmentation GO:0035282 93 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
regulation of exocytosis GO:0017157 61 0.013
positive regulation of homeostatic process GO:0032846 64 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
circulatory system process GO:0003013 197 0.013
histone modification GO:0016570 159 0.013
cellular amide metabolic process GO:0043603 58 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
insulin metabolic process GO:1901142 3 0.013
t cell proliferation GO:0042098 120 0.013
regulation of cell adhesion GO:0030155 154 0.013
plasma membrane organization GO:0007009 90 0.013
cellular response to acid chemical GO:0071229 68 0.013
protein import GO:0017038 101 0.013
negative regulation of cell activation GO:0050866 111 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
positive regulation of protein transport GO:0051222 93 0.013
negative regulation of cell motility GO:2000146 61 0.013
compound eye development GO:0048749 1 0.013
nephron epithelium development GO:0072009 92 0.013
actin filament polymerization GO:0030041 44 0.013
leukocyte differentiation GO:0002521 342 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
regulation of muscle system process GO:0090257 80 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
acetate ester transport GO:1901374 2 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.012
digestive tract morphogenesis GO:0048546 147 0.012

Serpine2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.104
nervous system disease DOID:863 0 0.104
myopathy DOID:423 0 0.070
muscular disease DOID:0080000 0 0.070
musculoskeletal system disease DOID:17 0 0.070
muscle tissue disease DOID:66 0 0.070
central nervous system disease DOID:331 0 0.032
sensory system disease DOID:0050155 0 0.026
eye and adnexa disease DOID:1492 0 0.026
disease of metabolism DOID:0014667 0 0.023
acquired metabolic disease DOID:0060158 0 0.023
retinal disease DOID:5679 0 0.015
retinal degeneration DOID:8466 0 0.015
eye disease DOID:5614 0 0.015
neuromuscular disease DOID:440 0 0.014
charcot marie tooth disease DOID:10595 0 0.014
neuropathy DOID:870 0 0.014
immune system disease DOID:2914 0 0.014