Mus musculus

11 known processes

Eif4h

eukaryotic translation initiation factor 4H

(Aliases: Ef4h,Wscr1,mKIAA0038,D5Ertd355e,E430026L18Rik,AU018978,Wbscr1)

Eif4h biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pole plasm assembly GO:0007315 2 0.295
oocyte axis specification GO:0007309 2 0.178
oocyte anterior posterior axis specification GO:0007314 2 0.168
meiotic cell cycle GO:0051321 122 0.131
rna splicing via transesterification reactions GO:0000375 43 0.119
oocyte construction GO:0007308 2 0.118
macromolecule catabolic process GO:0009057 281 0.085
ribonucleoprotein complex subunit organization GO:0071826 28 0.082
germ cell development GO:0007281 185 0.081
cellular response to dna damage stimulus GO:0006974 207 0.080
intracellular mrna localization GO:0008298 4 0.078
regulation of kinase activity GO:0043549 249 0.077
meiotic nuclear division GO:0007126 115 0.076
negative regulation of molecular function GO:0044092 258 0.076
ion transmembrane transport GO:0034220 361 0.069
cellular macromolecule catabolic process GO:0044265 206 0.068
transmembrane transport GO:0055085 412 0.067
organelle fission GO:0048285 170 0.061
positive regulation of protein modification process GO:0031401 299 0.059
regulation of cell cycle process GO:0010564 160 0.055
mrna splicing via spliceosome GO:0000398 43 0.054
apoptotic signaling pathway GO:0097190 306 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.053
regulation of transferase activity GO:0051338 263 0.052
cellular amino acid metabolic process GO:0006520 103 0.052
mrna metabolic process GO:0016071 84 0.051
nucleoside phosphate metabolic process GO:0006753 338 0.049
cellular protein catabolic process GO:0044257 155 0.049
cell division GO:0051301 120 0.048
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
purine nucleotide metabolic process GO:0006163 302 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.047
nuclear division GO:0000280 158 0.045
positive regulation of protein phosphorylation GO:0001934 242 0.045
organic cyclic compound catabolic process GO:1901361 295 0.043
aromatic compound catabolic process GO:0019439 286 0.043
response to organonitrogen compound GO:0010243 246 0.043
nucleoside phosphate catabolic process GO:1901292 222 0.042
regulation of protein kinase activity GO:0045859 232 0.042
regulation of organelle organization GO:0033043 289 0.042
cellular response to lipid GO:0071396 145 0.040
peptidyl amino acid modification GO:0018193 336 0.039
maternal determination of anterior posterior axis embryo GO:0008358 2 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
cytoplasmic transport GO:0016482 234 0.038
response to organic cyclic compound GO:0014070 198 0.038
ribonucleoside metabolic process GO:0009119 245 0.037
negative regulation of protein metabolic process GO:0051248 282 0.037
microtubule cytoskeleton organization GO:0000226 157 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.036
dna repair GO:0006281 107 0.035
nucleotide catabolic process GO:0009166 217 0.034
regulation of cell division GO:0051302 76 0.034
rna processing GO:0006396 105 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
proteasomal protein catabolic process GO:0010498 98 0.032
purine containing compound metabolic process GO:0072521 311 0.032
male gamete generation GO:0048232 285 0.032
positive regulation of cell death GO:0010942 224 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
heterocycle catabolic process GO:0046700 280 0.030
regulation of mrna splicing via spliceosome GO:0048024 32 0.030
nucleotide metabolic process GO:0009117 332 0.029
negative regulation of protein modification process GO:0031400 163 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.029
microtubule based process GO:0007017 236 0.029
positive regulation of apoptotic process GO:0043065 217 0.028
mrna processing GO:0006397 63 0.028
regulation of defense response GO:0031347 233 0.028
rna splicing GO:0008380 54 0.028
spermatogenesis GO:0007283 284 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
cellular amine metabolic process GO:0044106 44 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
protein processing GO:0016485 163 0.027
ubiquitin dependent protein catabolic process GO:0006511 129 0.027
lateral inhibition GO:0046331 1 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.026
regulation of system process GO:0044057 200 0.026
signal transduction by p53 class mediator GO:0072331 51 0.026
translation GO:0006412 93 0.026
anion transport GO:0006820 177 0.025
ras protein signal transduction GO:0007265 77 0.025
response to lipopolysaccharide GO:0032496 128 0.025
protein catabolic process GO:0030163 221 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
cell adhesion GO:0007155 329 0.025
purine containing compound catabolic process GO:0072523 213 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
macromolecule methylation GO:0043414 120 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
multi multicellular organism process GO:0044706 109 0.024
nucleoside monophosphate metabolic process GO:0009123 85 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
cellular ketone metabolic process GO:0042180 84 0.023
regulation of hydrolase activity GO:0051336 246 0.023
regulation of nuclear division GO:0051783 56 0.023
organic anion transport GO:0015711 137 0.023
developmental maturation GO:0021700 193 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
regulation of cell cycle GO:0051726 281 0.022
oogenesis GO:0048477 56 0.022
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.022
regulation of protein localization GO:0032880 231 0.022
regionalization GO:0003002 337 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
nitrogen compound transport GO:0071705 271 0.021
positive regulation of transferase activity GO:0051347 167 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
amine metabolic process GO:0009308 45 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
blood vessel morphogenesis GO:0048514 285 0.021
protein maturation GO:0051604 176 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.020
circadian regulation of gene expression GO:0032922 48 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
regulation of proteolysis GO:0030162 164 0.020
cell maturation GO:0048469 127 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
oocyte differentiation GO:0009994 35 0.020
regulation of ion transport GO:0043269 215 0.020
oocyte development GO:0048599 33 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
endocytosis GO:0006897 168 0.019
blood circulation GO:0008015 195 0.019
regulation of anatomical structure size GO:0090066 178 0.019
positive regulation of nervous system development GO:0051962 221 0.019
regulation of hormone levels GO:0010817 211 0.019
inflammatory response GO:0006954 244 0.019
regulation of meiotic cell cycle GO:0051445 34 0.019
muscle system process GO:0003012 141 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
female gamete generation GO:0007292 74 0.019
nucleoside catabolic process GO:0009164 206 0.018
cellular lipid metabolic process GO:0044255 323 0.018
segmentation GO:0035282 93 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
male meiosis i GO:0007141 16 0.018
cellular response to molecule of bacterial origin GO:0071219 83 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
negative regulation of transferase activity GO:0051348 85 0.018
regulation of mrna metabolic process GO:1903311 43 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.018
regulation of cell migration GO:0030334 219 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
action potential GO:0001508 78 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
oxidation reduction process GO:0055114 342 0.018
locomotory behavior GO:0007626 195 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
cation transport GO:0006812 399 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
cellular protein complex assembly GO:0043623 116 0.017
asymmetric stem cell division GO:0098722 3 0.017
development of primary sexual characteristics GO:0045137 143 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
protein ubiquitination GO:0016567 171 0.017
actin cytoskeleton organization GO:0030036 220 0.016
regulation of reproductive process GO:2000241 66 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
dna metabolic process GO:0006259 303 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
protein methylation GO:0006479 81 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
lipid biosynthetic process GO:0008610 179 0.016
organic acid biosynthetic process GO:0016053 86 0.016
transmission of nerve impulse GO:0019226 76 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
regulation of protein transport GO:0051223 163 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
myosin filament assembly GO:0031034 2 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
multicellular organismal signaling GO:0035637 91 0.016
positive regulation of kinase activity GO:0033674 155 0.016
organonitrogen compound catabolic process GO:1901565 264 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
response to radiation GO:0009314 165 0.015
regulation of blood pressure GO:0008217 93 0.015
regulation of cell projection organization GO:0031344 206 0.015
methylation GO:0032259 134 0.015
nucleoside metabolic process GO:0009116 246 0.015
chromatin organization GO:0006325 206 0.015
spermatid development GO:0007286 108 0.015
regulation of map kinase activity GO:0043405 120 0.015
regulation of response to wounding GO:1903034 189 0.015
negative regulation of protein maturation GO:1903318 79 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
stem cell proliferation GO:0072089 117 0.015
muscle cell differentiation GO:0042692 261 0.015
maintenance of location GO:0051235 89 0.015
inorganic cation transmembrane transport GO:0098662 207 0.014
cation transmembrane transport GO:0098655 266 0.014
immune effector process GO:0002252 321 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
chromatin modification GO:0016568 187 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.014
rhythmic process GO:0048511 174 0.014
protein localization to organelle GO:0033365 185 0.014
regulation of inflammatory response GO:0050727 147 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
compound eye development GO:0048749 1 0.014
organophosphate catabolic process GO:0046434 232 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.014
positive regulation of mrna processing GO:0050685 16 0.014
single organism cell adhesion GO:0098602 156 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of chromosome organization GO:0033044 83 0.014
ossification GO:0001503 216 0.014
cellularization GO:0007349 1 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.014
mitotic cell cycle GO:0000278 195 0.014
regulation of intracellular transport GO:0032386 159 0.014
regulation of membrane potential GO:0042391 192 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
small molecule biosynthetic process GO:0044283 132 0.014
chemotaxis GO:0006935 247 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
placenta development GO:0001890 140 0.013
immunoglobulin production GO:0002377 73 0.013
rna interference GO:0016246 2 0.013
regulation of cell activation GO:0050865 289 0.013
positive regulation of rna splicing GO:0033120 12 0.013
l alpha amino acid transmembrane transport GO:1902475 23 0.013
carbohydrate homeostasis GO:0033500 128 0.013
regulation of mrna processing GO:0050684 41 0.013
fertilization GO:0009566 127 0.013
nuclear transport GO:0051169 139 0.013
regulation of cell size GO:0008361 72 0.013
regulation of cytokine production GO:0001817 266 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
sensory perception GO:0007600 245 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
body morphogenesis GO:0010171 45 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
regulation of neuron differentiation GO:0045664 281 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
protein targeting GO:0006605 143 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
neural precursor cell proliferation GO:0061351 121 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of peptidase activity GO:0052547 96 0.012
negative regulation of kinase activity GO:0033673 81 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.012
negative regulation of cell development GO:0010721 169 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
connective tissue development GO:0061448 179 0.012
regulation of extent of cell growth GO:0061387 52 0.012
organelle assembly GO:0070925 177 0.012
response to growth factor GO:0070848 198 0.012
meiosis i GO:0007127 60 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
neuronal action potential GO:0019228 54 0.012
negative regulation of cell cycle GO:0045786 123 0.012
anion transmembrane transport GO:0098656 71 0.012
negative regulation of protein processing GO:0010955 79 0.012
double strand break repair GO:0006302 48 0.012
cellular homeostasis GO:0019725 240 0.012
cytokine production GO:0001816 319 0.012
adult behavior GO:0030534 135 0.012
regulation of secretion GO:0051046 274 0.012
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.012
regulation of protein maturation GO:1903317 96 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
positive regulation of immune effector process GO:0002699 107 0.012
leukocyte mediated immunity GO:0002443 174 0.012
response to extracellular stimulus GO:0009991 127 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of protein catabolic process GO:0042176 108 0.011
positive regulation of cell development GO:0010720 237 0.011
protein alkylation GO:0008213 81 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
mapk cascade GO:0000165 281 0.011
primitive erythrocyte differentiation GO:0060319 3 0.011
asymmetric neuroblast division GO:0055059 1 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
immunoglobulin mediated immune response GO:0016064 69 0.011
regulation of cell growth GO:0001558 91 0.011
response to peptide hormone GO:0043434 127 0.011
multicellular organism growth GO:0035264 161 0.011
organelle localization GO:0051640 179 0.011
homeostasis of number of cells GO:0048872 210 0.011
response to light stimulus GO:0009416 135 0.011
negative regulation of proteolysis GO:0045861 74 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
spliceosomal complex disassembly GO:0000390 1 0.011
positive regulation of mrna metabolic process GO:1903313 17 0.011
cell fate commitment GO:0045165 210 0.011
cellular chemical homeostasis GO:0055082 215 0.011
multi organism behavior GO:0051705 62 0.011
membrane organization GO:0061024 245 0.011
respiratory system development GO:0060541 190 0.011
dephosphorylation GO:0016311 129 0.011
skeletal system development GO:0001501 356 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of cell motility GO:2000145 236 0.011
cellular amino acid biosynthetic process GO:0008652 22 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
b cell activation GO:0042113 161 0.011
regulation of establishment of protein localization GO:0070201 181 0.010
cell type specific apoptotic process GO:0097285 268 0.010
negative regulation of organelle organization GO:0010639 90 0.010
wnt signaling pathway GO:0016055 188 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
regulation of multi organism process GO:0043900 111 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
positive regulation of proteolysis GO:0045862 85 0.010
protein localization to nucleus GO:0034504 121 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
carboxylic acid transport GO:0046942 100 0.010
positive regulation of protein transport GO:0051222 93 0.010
calcium ion transport GO:0006816 159 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
cell recognition GO:0008037 83 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
intracellular protein transport GO:0006886 204 0.010

Eif4h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
central nervous system disease DOID:331 0 0.030
neurodegenerative disease DOID:1289 0 0.021
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of mental health DOID:150 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.010