Mus musculus

46 known processes

Aif1

allograft inflammatory factor 1

(Aliases: D17H6S50E,AIF-1,Iba1,G1,AI607846)

Aif1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein activation cascade GO:0072376 19 0.786
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.765
regulation of cell activation GO:0050865 289 0.634
Human
metanephric glomerular epithelium development GO:0072244 3 0.627
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.541
metanephric mesenchymal cell migration GO:0035789 2 0.475
immunoglobulin mediated immune response GO:0016064 69 0.461
negative regulation of gluconeogenesis GO:0045721 9 0.456
regulation of intracellular transport GO:0032386 159 0.409
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.402
regulation of monocyte chemotaxis GO:0090025 3 0.383
Human
sequestering of metal ion GO:0051238 19 0.345
regulation of type iia hypersensitivity GO:0001796 4 0.337
immune effector process GO:0002252 321 0.332
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.329
regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000583 2 0.314
myeloid cell differentiation GO:0030099 233 0.308
negative regulation of immune system process GO:0002683 209 0.295
fatty acid metabolic process GO:0006631 121 0.292
regulation of protein kinase activity GO:0045859 232 0.288
cation transport GO:0006812 399 0.280
metanephric glomerular epithelial cell development GO:0072313 2 0.279
positive regulation of endocytosis GO:0045807 42 0.275
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.275
positive regulation of secretion GO:0051047 130 0.274
cellular lipid metabolic process GO:0044255 323 0.262
regulation of lymphocyte activation GO:0051249 240 0.261
Human
cellular homeostasis GO:0019725 240 0.253
sequestering of calcium ion GO:0051208 18 0.253
regulation of cellular ketone metabolic process GO:0010565 66 0.246
regulation of mapk cascade GO:0043408 248 0.234
regulation of myeloid cell differentiation GO:0045637 96 0.226
regulation of inflammatory response GO:0050727 147 0.221
regulation of transferase activity GO:0051338 263 0.220
antigen processing and presentation of peptide antigen GO:0048002 29 0.219
cellular chemical homeostasis GO:0055082 215 0.218
leukocyte mediated immunity GO:0002443 174 0.217
actin cytoskeleton organization GO:0030036 220 0.212
mapk cascade GO:0000165 281 0.210
regulation of cell migration GO:0030334 219 0.201
Human Rat
regulation of vesicle mediated transport GO:0060627 139 0.193
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.191
calcium ion transport GO:0006816 159 0.191
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.189
amine metabolic process GO:0009308 45 0.187
chemotaxis GO:0006935 247 0.185
Human
positive regulation of calcium mediated signaling GO:0050850 15 0.179
cell migration involved in metanephros development GO:0035788 2 0.173
antigen processing and presentation GO:0019882 47 0.173
negative regulation of type i hypersensitivity GO:0001811 1 0.171
regulation of protein serine threonine kinase activity GO:0071900 157 0.162
cation homeostasis GO:0055080 212 0.162
negative regulation of cell proliferation GO:0008285 296 0.161
Human
negative regulation of hypersensitivity GO:0002884 3 0.161
detection of oxidative stress GO:0070994 1 0.160
positive regulation of cytokine secretion GO:0050715 41 0.156
positive regulation of secretion by cell GO:1903532 114 0.155
membrane organization GO:0061024 245 0.154
leukocyte differentiation GO:0002521 342 0.154
metanephric glomerular visceral epithelial cell differentiation GO:0072248 2 0.152
metal ion homeostasis GO:0055065 189 0.151
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.149
cytosolic calcium ion transport GO:0060401 48 0.147
cytosolic calcium ion homeostasis GO:0051480 70 0.145
positive regulation of metanephric glomerular visceral epithelial cell development GO:2000478 1 0.143
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.143
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.142
positive regulation of metanephric glomerulus development GO:0072300 4 0.141
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.138
positive regulation of phagocytosis GO:0050766 26 0.137
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.136
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.136
negative regulation of lymphocyte activation GO:0051250 91 0.135
regulation of homeostatic process GO:0032844 182 0.135
activation of immune response GO:0002253 138 0.134
muscle cell differentiation GO:0042692 261 0.133
positive regulation of cellular amine metabolic process GO:0033240 5 0.132
cerebellar granular layer development GO:0021681 13 0.131
glomerular visceral epithelial cell development GO:0072015 6 0.129
regulation of endocytosis GO:0030100 69 0.124
monocarboxylic acid metabolic process GO:0032787 191 0.120
positive regulation of protein kinase b signaling GO:0051897 32 0.120
lipid modification GO:0030258 65 0.120
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.119
synapse organization GO:0050808 125 0.119
regulation of kinase activity GO:0043549 249 0.118
metanephric glomerular epithelial cell differentiation GO:0072312 2 0.118
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.117
cellular ketone metabolic process GO:0042180 84 0.117
b cell mediated immunity GO:0019724 71 0.115
cellular calcium ion homeostasis GO:0006874 119 0.115
granulocyte macrophage colony stimulating factor biosynthetic process GO:0042253 2 0.114
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.113
renal filtration cell differentiation GO:0061318 10 0.112
renal system development GO:0072001 225 0.111
cell cell adhesion GO:0098609 41 0.110
maintenance of location GO:0051235 89 0.110
cytoplasmic transport GO:0016482 234 0.109
negative regulation of protein modification process GO:0031400 163 0.106
regulation of mast cell activation GO:0033003 21 0.105
regulation of neuron apoptotic process GO:0043523 122 0.104
kidney development GO:0001822 213 0.104
cytokine production GO:0001816 319 0.103
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.103
release of sequestered calcium ion into cytosol GO:0051209 42 0.102
cellular divalent inorganic cation homeostasis GO:0072503 127 0.101
negative regulation of kinase activity GO:0033673 81 0.100
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.100
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.099
positive regulation of type ii hypersensitivity GO:0002894 4 0.099
cerebellar granule cell differentiation GO:0021707 9 0.098
immunoglobulin production in mucosal tissue GO:0002426 3 0.098
myeloid leukocyte mediated immunity GO:0002444 42 0.098
cellular ion homeostasis GO:0006873 165 0.097
regulation of protein transport GO:0051223 163 0.097
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.097
fat cell differentiation GO:0045444 160 0.096
positive regulation of synapse assembly GO:0051965 18 0.096
positive regulation of type iii hypersensitivity GO:0001805 3 0.096
glucose transport GO:0015758 56 0.095
positive regulation of glomerulus development GO:0090193 5 0.094
cell chemotaxis GO:0060326 81 0.094
Human
divalent inorganic cation homeostasis GO:0072507 138 0.094
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.093
cellular response to biotic stimulus GO:0071216 92 0.093
calcium ion transport into cytosol GO:0060402 48 0.093
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.093
regulation of renal albumin absorption GO:2000532 1 0.092
regulation of myeloid leukocyte differentiation GO:0002761 58 0.092
cellular metal ion homeostasis GO:0006875 151 0.091
membrane invagination GO:0010324 17 0.091
positive regulation of transferase activity GO:0051347 167 0.091
regulation of phagocytosis GO:0050764 33 0.090
cell adhesion GO:0007155 329 0.090
regulation of secretion by cell GO:1903530 249 0.090
regulation of map kinase activity GO:0043405 120 0.089
rho protein signal transduction GO:0007266 32 0.089
negative regulation of map kinase activity GO:0043407 34 0.088
regulation of lipid metabolic process GO:0019216 118 0.087
humoral immune response GO:0006959 57 0.087
organic acid biosynthetic process GO:0016053 86 0.087
toxin catabolic process GO:0009407 1 0.085
positive regulation of protein modification process GO:0031401 299 0.085
Rat
cell migration involved in kidney development GO:0035787 3 0.085
negative regulation of intracellular signal transduction GO:1902532 167 0.085
regulation of secretion GO:0051046 274 0.085
negative regulation of transferase activity GO:0051348 85 0.084
myeloid cell activation involved in immune response GO:0002275 34 0.084
positive regulation of cellular component biogenesis GO:0044089 94 0.084
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.083
renal protein absorption GO:0097017 1 0.083
calcium ion homeostasis GO:0055074 127 0.083
calcium mediated signaling GO:0019722 46 0.081
fatty acid biosynthetic process GO:0006633 41 0.081
negative regulation of protein metabolic process GO:0051248 282 0.080
negative regulation of myeloid cell differentiation GO:0045638 38 0.079
regulated secretory pathway GO:0045055 32 0.079
negative regulation of mapk cascade GO:0043409 65 0.079
myeloid leukocyte activation GO:0002274 83 0.078
g protein coupled receptor signaling pathway GO:0007186 243 0.077
glomerulus development GO:0032835 40 0.077
cellular amine metabolic process GO:0044106 44 0.077
regulation of lymphocyte proliferation GO:0050670 117 0.076
Human
divalent inorganic cation transport GO:0072511 178 0.076
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.076
defense response to other organism GO:0098542 197 0.075
lymphocyte proliferation GO:0046651 164 0.075
Human
regulation of defense response GO:0031347 233 0.075
regulation of jnk cascade GO:0046328 62 0.073
glomerular epithelial cell development GO:0072310 6 0.073
cell differentiation involved in metanephros development GO:0072202 12 0.073
fatty acid derivative biosynthetic process GO:1901570 15 0.072
adaptive immune response GO:0002250 155 0.071
leukotriene metabolic process GO:0006691 7 0.071
positive regulation of intracellular transport GO:0032388 70 0.071
regulation of type ii hypersensitivity GO:0002892 4 0.071
fc epsilon receptor signaling pathway GO:0038095 3 0.069
exocytosis GO:0006887 121 0.069
lymphocyte mediated immunity GO:0002449 139 0.069
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.068
hexose transport GO:0008645 56 0.067
regulation of type iii hypersensitivity GO:0001803 3 0.067
immune response activating signal transduction GO:0002757 116 0.067
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.066
negative regulation of phosphorylation GO:0042326 166 0.065
immune response regulating signaling pathway GO:0002764 125 0.065
mast cell activation GO:0045576 27 0.064
negative regulation of metanephros development GO:0072217 6 0.064
ear development GO:0043583 200 0.064
negative regulation of phosphorus metabolic process GO:0010563 184 0.063
myeloid leukocyte differentiation GO:0002573 119 0.063
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.062
carbohydrate transport GO:0008643 62 0.062
cellular amino acid metabolic process GO:0006520 103 0.062
negative regulation of inflammatory response GO:0050728 61 0.062
cellular carbohydrate metabolic process GO:0044262 119 0.062
eosinophil migration GO:0072677 3 0.061
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.061
unsaturated fatty acid biosynthetic process GO:0006636 15 0.061
interleukin 3 production GO:0032632 3 0.061
mast cell degranulation GO:0043303 19 0.061
brown fat cell differentiation GO:0050873 36 0.061
leukocyte activation involved in immune response GO:0002366 126 0.060
monocarboxylic acid biosynthetic process GO:0072330 61 0.060
regulation of response to wounding GO:1903034 189 0.060
cerebellum morphogenesis GO:0021587 42 0.060
regulation of cellular amine metabolic process GO:0033238 20 0.059
regulation of leukocyte differentiation GO:1902105 159 0.059
glucose import GO:0046323 32 0.059
positive regulation of cell migration GO:0030335 109 0.058
Human Rat
activation of mapk activity GO:0000187 59 0.058
monosaccharide transport GO:0015749 58 0.058
toll like receptor 7 signaling pathway GO:0034154 4 0.058
regulation of cell motility GO:2000145 236 0.057
Human Rat
positive regulation of kinase activity GO:0033674 155 0.057
negative regulation of metanephric mesenchymal cell migration GO:2000590 1 0.057
regulation of protein secretion GO:0050708 82 0.057
regulation of natural killer cell activation GO:0032814 22 0.057
positive regulation of immune effector process GO:0002699 107 0.056
negative regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000584 2 0.056
carboxylic acid biosynthetic process GO:0046394 86 0.056
activation of jun kinase activity GO:0007257 15 0.056
cerebellum development GO:0021549 77 0.056
regulation of ion homeostasis GO:2000021 64 0.055
cell junction maintenance GO:0034331 4 0.055
negative regulation of homeostatic process GO:0032845 71 0.055
positive regulation of mapk cascade GO:0043410 170 0.055
regulation of adiponectin secretion GO:0070163 2 0.054
endocytosis GO:0006897 168 0.054
central nervous system neuron differentiation GO:0021953 162 0.053
positive regulation of cytokine production GO:0001819 174 0.053
carbohydrate homeostasis GO:0033500 128 0.053
positive regulation of protein kinase activity GO:0045860 144 0.053
regulation of organelle organization GO:0033043 289 0.052
cerebellar cortex development GO:0021695 48 0.052
homeostasis of number of cells GO:0048872 210 0.052
regulation of ion transport GO:0043269 215 0.052
negative regulation of leukocyte proliferation GO:0070664 46 0.052
positive regulation of fatty acid metabolic process GO:0045923 8 0.051
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.051
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.051
regulation of system process GO:0044057 200 0.051
Rat
lipid oxidation GO:0034440 29 0.051
negative regulation of protein phosphorylation GO:0001933 126 0.050
myotube differentiation GO:0014902 105 0.050
unsaturated fatty acid metabolic process GO:0033559 31 0.050
negative regulation of phagocytosis GO:0050765 4 0.049
leukocyte proliferation GO:0070661 172 0.049
Human
positive regulation of glucose transport GO:0010828 16 0.049
inflammatory response GO:0006954 244 0.049
Rat
regulation of establishment of protein localization GO:0070201 181 0.049
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
oxidation reduction process GO:0055114 342 0.048
metanephros development GO:0001656 79 0.048
positive regulation of organelle organization GO:0010638 128 0.048
negative regulation of t cell proliferation GO:0042130 38 0.047
positive regulation of adaptive immune response GO:0002821 61 0.047
cytokine secretion GO:0050663 72 0.047
nephron development GO:0072006 109 0.047
regulation of adaptive immune response GO:0002819 90 0.047
mitotic cell cycle GO:0000278 195 0.047
Human
cell differentiation involved in kidney development GO:0061005 33 0.046
negative regulation of adaptive immune response GO:0002820 25 0.046
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.046
positive regulation of thymocyte migration GO:2000412 2 0.045
positive regulation of protein phosphorylation GO:0001934 242 0.045
Rat
adiponectin secretion GO:0070162 2 0.045
regulation of t cell proliferation GO:0042129 92 0.045
Human
positive regulation of camp dependent protein kinase activity GO:2000481 3 0.045
nephron epithelium development GO:0072009 92 0.045
antigen receptor mediated signaling pathway GO:0050851 64 0.044
negative regulation of lymphocyte proliferation GO:0050672 45 0.044
stress activated protein kinase signaling cascade GO:0031098 81 0.044
fatty acid oxidation GO:0019395 28 0.044
metencephalon development GO:0022037 89 0.044
glycerolipid metabolic process GO:0046486 122 0.044
regulation of type i hypersensitivity GO:0001810 4 0.043
cytokine metabolic process GO:0042107 71 0.043
developmental maturation GO:0021700 193 0.043
spermatogenesis GO:0007283 284 0.043
regulation of glucose transport GO:0010827 32 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
t cell activation GO:0042110 289 0.042
Human
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.042
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 0.042
axonogenesis GO:0007409 274 0.042
cellular response to growth factor stimulus GO:0071363 197 0.041
cerebellar granular layer formation GO:0021684 9 0.041
regulation of calcium ion transport into cytosol GO:0010522 31 0.041
positive regulation of leukocyte mediated immunity GO:0002705 70 0.041
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.041
organic acid catabolic process GO:0016054 51 0.041
regulation of eosinophil migration GO:2000416 2 0.040
innate immune response GO:0045087 157 0.040
Human Rat
positive regulation of monocyte chemotaxis GO:0090026 2 0.040
Human
blood coagulation GO:0007596 76 0.040
striated muscle tissue development GO:0014706 293 0.040
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.040
hexose biosynthetic process GO:0019319 39 0.040
positive regulation of jnk cascade GO:0046330 46 0.040
stress activated mapk cascade GO:0051403 80 0.039
regulation of b cell chemotaxis GO:2000537 2 0.039
regulation of protein localization GO:0032880 231 0.039
neuron apoptotic process GO:0051402 142 0.039
erk1 and erk2 cascade GO:0070371 77 0.039
regulation of cellular component biogenesis GO:0044087 181 0.039
regulation of innate immune response GO:0045088 91 0.038
positive regulation of protein secretion GO:0050714 52 0.038
monocarboxylic acid catabolic process GO:0072329 27 0.038
epithelial cell differentiation involved in kidney development GO:0035850 23 0.038
hematopoietic progenitor cell differentiation GO:0002244 143 0.038
fatty acid derivative metabolic process GO:1901568 33 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.038
b cell activation GO:0042113 161 0.038
regulation of natural killer cell chemotaxis GO:2000501 1 0.038
b cell receptor signaling pathway GO:0050853 20 0.038
regulation of fat cell differentiation GO:0045598 81 0.037
sensory perception GO:0007600 245 0.037
positive regulation of lipid metabolic process GO:0045834 40 0.037
purine nucleoside metabolic process GO:0042278 241 0.037
positive regulation of defense response GO:0031349 124 0.037
positive regulation of renal albumin absorption GO:2000534 1 0.037
monosaccharide metabolic process GO:0005996 106 0.036
glucose metabolic process GO:0006006 92 0.036
positive regulation of type iia hypersensitivity GO:0001798 4 0.036
defense response to bacterium GO:0042742 119 0.036
dendritic cell differentiation GO:0097028 26 0.036
male gamete generation GO:0048232 285 0.036
metanephric nephron development GO:0072210 34 0.036
hormone secretion GO:0046879 128 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.036
regulation of t helper 1 cell cytokine production GO:2000554 1 0.035
mast cell mediated immunity GO:0002448 20 0.035
regulation of hormone levels GO:0010817 211 0.035
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.035
glucose homeostasis GO:0042593 128 0.035
l amino acid transport GO:0015807 32 0.035
macrophage migration inhibitory factor signaling pathway GO:0035691 2 0.035
basal protein localization GO:0045175 1 0.035
fatty acid beta oxidation GO:0006635 16 0.035
regulation of metal ion transport GO:0010959 106 0.034
positive regulation of nucleotide catabolic process GO:0030813 88 0.034
regulation of cellular response to stress GO:0080135 159 0.033
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.033
cellular response to interferon gamma GO:0071346 25 0.033
Human Rat
regulation of gluconeogenesis GO:0006111 30 0.033
glomerular epithelial cell differentiation GO:0072311 10 0.033
cellular response to insulin stimulus GO:0032869 78 0.033
muscle cell development GO:0055001 133 0.033
natural killer cell chemotaxis GO:0035747 1 0.033
cerebellar cortex formation GO:0021697 22 0.033
regulation of cytoplasmic transport GO:1903649 112 0.032
response to growth factor GO:0070848 198 0.032
negative regulation of granulocyte differentiation GO:0030853 3 0.032
muscle tissue development GO:0060537 308 0.032
cellular response to molecule of bacterial origin GO:0071219 83 0.032
small molecule catabolic process GO:0044282 71 0.032
negative regulation of molecular function GO:0044092 258 0.032
positive regulation of glucose import GO:0046326 14 0.031
metanephric nephron epithelium development GO:0072243 19 0.031
negative regulation of response to wounding GO:1903035 77 0.031
positive regulation of jun kinase activity GO:0043507 30 0.031
response to peptide hormone GO:0043434 127 0.031
positive regulation of inflammatory response GO:0050729 47 0.031
protein kinase b signaling GO:0043491 74 0.031
negative regulation of phospholipase activity GO:0010519 4 0.031
second messenger mediated signaling GO:0019932 73 0.031
ribose phosphate metabolic process GO:0019693 291 0.030
cerebellar cortex morphogenesis GO:0021696 32 0.030
positive regulation of eosinophil migration GO:2000418 2 0.030
regulation of glomerulus development GO:0090192 6 0.029
regionalization GO:0003002 337 0.029
negative regulation of humoral immune response mediated by circulating immunoglobulin GO:0002924 3 0.029
integrin mediated signaling pathway GO:0007229 27 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
Rat
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
protein heterooligomerization GO:0051291 14 0.028
regulation of leukocyte mediated immunity GO:0002703 104 0.028
regulation of t helper 2 cell cytokine production GO:2000551 3 0.028
lipid catabolic process GO:0016042 69 0.028
carbohydrate metabolic process GO:0005975 230 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.027
thymocyte migration GO:0072679 2 0.027
positive regulation of tumor necrosis factor production GO:0032760 30 0.027
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 7 0.027
response to monosaccharide GO:0034284 67 0.027
single organism cell adhesion GO:0098602 156 0.027
kidney epithelium development GO:0072073 121 0.027
antibody dependent cellular cytotoxicity GO:0001788 2 0.027
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.026
negative regulation of cell activation GO:0050866 111 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
neutrophil chemotaxis GO:0030593 36 0.026
carboxylic acid catabolic process GO:0046395 51 0.026
gtp catabolic process GO:0006184 143 0.026
myotube cell development GO:0014904 60 0.026
osteoclast differentiation GO:0030316 62 0.026
carbohydrate biosynthetic process GO:0016051 74 0.026
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
auditory receptor cell fate determination GO:0042668 3 0.026
negative regulation of cell motility GO:2000146 61 0.026
Human
positive regulation of neuron death GO:1901216 28 0.025
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.025
regulation of leukocyte apoptotic process GO:2000106 56 0.025
leukocyte chemotaxis GO:0030595 69 0.025
Human
mitotic cell cycle process GO:1903047 159 0.025
Human
positive regulation of dna biosynthetic process GO:2000573 4 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
positive regulation of cell activation GO:0050867 158 0.025
Human
astrocyte cell migration GO:0043615 3 0.025
ras protein signal transduction GO:0007265 77 0.025
regulation of actin filament based process GO:0032970 99 0.025
regulation of mast cell activation involved in immune response GO:0033006 17 0.025
regulation of osteoclast differentiation GO:0045670 36 0.025
anatomical structure homeostasis GO:0060249 145 0.025
regulation of humoral immune response GO:0002920 22 0.025
synapse assembly GO:0007416 56 0.025
positive regulation of smooth muscle cell migration GO:0014911 4 0.025
Human
granulocyte migration GO:0097530 43 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.024
regulation of peptide secretion GO:0002791 77 0.024
production of molecular mediator of immune response GO:0002440 103 0.024
response to oxidative stress GO:0006979 123 0.024
Rat
cell recognition GO:0008037 83 0.024
positive regulation of leukocyte degranulation GO:0043302 10 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
b cell chemotaxis GO:0035754 3 0.024
t cell differentiation GO:0030217 174 0.024
organic hydroxy compound transport GO:0015850 93 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.024
lysosome localization GO:0032418 20 0.024
mature dendritic cell differentiation GO:0097029 3 0.024
organelle assembly GO:0070925 177 0.024
hypersensitivity GO:0002524 10 0.024
complement activation classical pathway GO:0006958 2 0.024
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.023
lipid biosynthetic process GO:0008610 179 0.023
regulation of metanephric glomerular visceral epithelial cell development GO:2000477 1 0.023
negative regulation of leukocyte mediated immunity GO:0002704 29 0.023
regulation of dendritic cell dendrite assembly GO:2000547 2 0.023
i kappab kinase nf kappab signaling GO:0007249 85 0.023
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.023
regulation of t cell activation GO:0050863 170 0.023
Human
purine ribonucleotide catabolic process GO:0009154 208 0.023
hindbrain development GO:0030902 128 0.022
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.022
interleukin 12 secretion GO:0072610 3 0.022
toll like receptor 9 signaling pathway GO:0034162 6 0.022
urogenital system development GO:0001655 261 0.022
positive regulation of adiponectin secretion GO:0070165 1 0.022
response to insulin GO:0032868 100 0.022
striated muscle cell development GO:0055002 125 0.022
single organismal cell cell adhesion GO:0016337 131 0.022
neuron death GO:0070997 154 0.022
peptidyl amino acid modification GO:0018193 336 0.022
positive regulation of protein transport GO:0051222 93 0.022
skeletal muscle organ development GO:0060538 163 0.022
positive regulation of kidney development GO:0090184 28 0.022
glycoprotein metabolic process GO:0009100 116 0.022
actin filament bundle assembly GO:0051017 40 0.021
actin filament organization GO:0007015 113 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
antigen processing and presentation of exogenous antigen GO:0019884 26 0.021
jnk cascade GO:0007254 72 0.021
cellular response to peptide hormone stimulus GO:0071375 92 0.021
nitrogen compound transport GO:0071705 271 0.021
melanocyte migration GO:0097324 2 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
regulation of carbohydrate metabolic process GO:0006109 75 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
regulation of erk1 and erk2 cascade GO:0070372 71 0.021
positive regulation of response to wounding GO:1903036 66 0.021
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
positive regulation of homeostatic process GO:0032846 64 0.021
regulation of blood circulation GO:1903522 93 0.021
regulation of metanephros development GO:0072215 15 0.021
metanephric epithelium development GO:0072207 21 0.021
dendritic cell dendrite assembly GO:0097026 2 0.021
embryonic organ morphogenesis GO:0048562 276 0.020
regulation of thymocyte migration GO:2000410 2 0.020
regulation of retina development in camera type eye GO:1902866 3 0.020
regulation of kidney development GO:0090183 40 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
positive regulation of exocytosis GO:0045921 20 0.020
actin polymerization or depolymerization GO:0008154 54 0.020
Human
cell cell junction organization GO:0045216 72 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
Rat
negative regulation of fat cell differentiation GO:0045599 36 0.020
regulation of protein kinase b signaling GO:0051896 56 0.020

Aif1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025