Mus musculus

0 known processes

Eif4b

eukaryotic translation initiation factor 4B

(Aliases: AL024095,C85189,2310046H11Rik,Eif4a2)

Eif4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translational initiation GO:0006413 24 0.130
cellular amino acid metabolic process GO:0006520 103 0.103
histone modification GO:0016570 159 0.102
mitotic cell cycle GO:0000278 195 0.092
macromolecule catabolic process GO:0009057 281 0.073
regulation of cellular amine metabolic process GO:0033238 20 0.071
mitotic cell cycle process GO:1903047 159 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.069
chromatin organization GO:0006325 206 0.063
protein modification by small protein conjugation or removal GO:0070647 207 0.063
cellular amine metabolic process GO:0044106 44 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.062
cellular macromolecule catabolic process GO:0044265 206 0.062
cellular ketone metabolic process GO:0042180 84 0.060
leukocyte differentiation GO:0002521 342 0.057
protein modification by small protein conjugation GO:0032446 187 0.057
circadian rhythm GO:0007623 114 0.053
peptidyl amino acid modification GO:0018193 336 0.053
translation GO:0006412 93 0.050
cellular response to dna damage stimulus GO:0006974 207 0.048
regulation of cell cycle GO:0051726 281 0.046
covalent chromatin modification GO:0016569 163 0.046
lymphocyte differentiation GO:0030098 242 0.046
amine metabolic process GO:0009308 45 0.044
negative regulation of protein metabolic process GO:0051248 282 0.044
negative regulation of phosphorus metabolic process GO:0010563 184 0.043
macromolecule methylation GO:0043414 120 0.043
heterocycle catabolic process GO:0046700 280 0.041
cellular protein catabolic process GO:0044257 155 0.041
chromatin modification GO:0016568 187 0.040
protein ubiquitination GO:0016567 171 0.040
rna processing GO:0006396 105 0.040
protein catabolic process GO:0030163 221 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.039
modification dependent macromolecule catabolic process GO:0043632 133 0.039
regulation of protein localization GO:0032880 231 0.039
regulation of mitotic cell cycle GO:0007346 126 0.038
response to oxidative stress GO:0006979 123 0.038
aromatic compound catabolic process GO:0019439 286 0.038
methylation GO:0032259 134 0.037
t cell activation GO:0042110 289 0.036
regulation of system process GO:0044057 200 0.035
organelle fission GO:0048285 170 0.034
wnt signaling pathway GO:0016055 188 0.033
protein modification by small protein removal GO:0070646 21 0.033
regulation of cellular component biogenesis GO:0044087 181 0.032
germ cell development GO:0007281 185 0.032
regulation of cell cycle process GO:0010564 160 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
regulation of mitotic cell cycle phase transition GO:1901990 73 0.030
dna repair GO:0006281 107 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
intrinsic apoptotic signaling pathway GO:0097193 132 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
rhythmic process GO:0048511 174 0.027
circadian regulation of gene expression GO:0032922 48 0.027
negative regulation of cellular amine metabolic process GO:0033239 1 0.027
dephosphorylation GO:0016311 129 0.027
meiotic nuclear division GO:0007126 115 0.027
histone lysine methylation GO:0034968 50 0.027
nuclear division GO:0000280 158 0.026
oxidation reduction process GO:0055114 342 0.026
modification dependent protein catabolic process GO:0019941 133 0.025
regulation of organelle organization GO:0033043 289 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
heart morphogenesis GO:0003007 178 0.025
cellular response to lipid GO:0071396 145 0.024
apoptotic signaling pathway GO:0097190 306 0.024
nuclear transport GO:0051169 139 0.024
striated muscle tissue development GO:0014706 293 0.024
regulation of proteolysis GO:0030162 164 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
response to organic cyclic compound GO:0014070 198 0.023
lateral inhibition GO:0046331 1 0.023
muscle system process GO:0003012 141 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.022
dna metabolic process GO:0006259 303 0.022
maintenance of location GO:0051235 89 0.022
myeloid cell differentiation GO:0030099 233 0.022
lymphocyte proliferation GO:0046651 164 0.022
purine containing compound metabolic process GO:0072521 311 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
immune effector process GO:0002252 321 0.022
cytoplasmic translational initiation GO:0002183 3 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
protein localization to nucleus GO:0034504 121 0.021
cell division GO:0051301 120 0.021
regulation of protein catabolic process GO:0042176 108 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
peptidyl lysine modification GO:0018205 77 0.021
positive regulation of cell development GO:0010720 237 0.021
response to light stimulus GO:0009416 135 0.021
protein localization to organelle GO:0033365 185 0.020
dendrite development GO:0016358 115 0.020
stem cell differentiation GO:0048863 268 0.020
response to radiation GO:0009314 165 0.020
leukocyte proliferation GO:0070661 172 0.020
regulation of cell activation GO:0050865 289 0.020
action potential GO:0001508 78 0.020
protein targeting GO:0006605 143 0.020
regulation of membrane potential GO:0042391 192 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
inflammatory response GO:0006954 244 0.020
single organism cell adhesion GO:0098602 156 0.019
positive regulation of cell death GO:0010942 224 0.019
cell type specific apoptotic process GO:0097285 268 0.019
blood vessel morphogenesis GO:0048514 285 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
canonical wnt signaling pathway GO:0060070 130 0.019
cytokine production GO:0001816 319 0.019
cytoplasmic transport GO:0016482 234 0.019
negative regulation of immune system process GO:0002683 209 0.019
locomotory behavior GO:0007626 195 0.019
cellularization GO:0007349 1 0.019
sensory perception GO:0007600 245 0.019
gland development GO:0048732 330 0.018
ossification GO:0001503 216 0.018
response to inactivity GO:0014854 4 0.018
nuclear import GO:0051170 95 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
protein targeting to vacuole GO:0006623 3 0.018
response to nutrient levels GO:0031667 109 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
regulation of defense response GO:0031347 233 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of asymmetric cell division GO:0009786 4 0.018
nucleotide metabolic process GO:0009117 332 0.018
organophosphate catabolic process GO:0046434 232 0.018
lipid localization GO:0010876 126 0.018
regulation of cell cycle phase transition GO:1901987 77 0.018
nitrogen compound transport GO:0071705 271 0.018
muscle tissue development GO:0060537 308 0.018
regulation of kinase activity GO:0043549 249 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
negative regulation of protein modification process GO:0031400 163 0.018
homeostasis of number of cells GO:0048872 210 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
purine nucleoside catabolic process GO:0006152 205 0.017
cation transmembrane transport GO:0098655 266 0.017
endomembrane system organization GO:0010256 147 0.017
positive regulation of protein modification process GO:0031401 299 0.017
gonad development GO:0008406 141 0.017
regulation of cell division GO:0051302 76 0.017
male gamete generation GO:0048232 285 0.017
mrna metabolic process GO:0016071 84 0.017
response to lipopolysaccharide GO:0032496 128 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
cellular lipid metabolic process GO:0044255 323 0.017
regulation of anatomical structure size GO:0090066 178 0.017
histone deubiquitination GO:0016578 2 0.017
regulation of muscle system process GO:0090257 80 0.017
signal transduction by p53 class mediator GO:0072331 51 0.017
positive regulation of defense response GO:0031349 124 0.017
neuron death GO:0070997 154 0.016
purine containing compound catabolic process GO:0072523 213 0.016
regulation of circadian rhythm GO:0042752 58 0.016
meiotic cell cycle GO:0051321 122 0.016
spermatogenesis GO:0007283 284 0.016
protein localization to plasma membrane GO:0072659 57 0.016
organic acid biosynthetic process GO:0016053 86 0.016
regulation of cellular response to stress GO:0080135 159 0.016
regulation of protein kinase activity GO:0045859 232 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
regulation of hormone levels GO:0010817 211 0.016
multicellular organismal signaling GO:0035637 91 0.016
multi organism behavior GO:0051705 62 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
multi multicellular organism process GO:0044706 109 0.016
response to drug GO:0042493 75 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
small molecule catabolic process GO:0044282 71 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
response to uv GO:0009411 44 0.015
regulation of lymphocyte anergy GO:0002911 4 0.015
nucleoside catabolic process GO:0009164 206 0.015
regulation of hydrolase activity GO:0051336 246 0.015
alpha beta t cell activation GO:0046631 91 0.015
myeloid cell homeostasis GO:0002262 114 0.015
response to inorganic substance GO:0010035 96 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
regulation of neuron differentiation GO:0045664 281 0.015
endocytosis GO:0006897 168 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
regulation of mrna metabolic process GO:1903311 43 0.015
regulation of translation GO:0006417 71 0.015
single organism nuclear import GO:1902593 95 0.015
chemotaxis GO:0006935 247 0.015
cellular alcohol biosynthetic process GO:0044108 3 0.015
establishment of protein localization to organelle GO:0072594 118 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
cellular response to abiotic stimulus GO:0071214 56 0.014
cell adhesion GO:0007155 329 0.014
transmission of nerve impulse GO:0019226 76 0.014
neuronal action potential GO:0019228 54 0.014
regulation of cytokine production GO:0001817 266 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
regulation of chromatin silencing GO:0031935 2 0.014
angiogenesis GO:0001525 201 0.014
positive regulation of cell cycle GO:0045787 92 0.014
meiotic cell cycle process GO:1903046 77 0.014
kidney development GO:0001822 213 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
innate immune response GO:0045087 157 0.014
carbohydrate metabolic process GO:0005975 230 0.014
response to acid chemical GO:0001101 111 0.014
negative regulation of wnt signaling pathway GO:0030178 73 0.014
regulation of cell motility GO:2000145 236 0.014
positive regulation of t cell anergy GO:0002669 4 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
transmembrane transport GO:0055085 412 0.014
blood circulation GO:0008015 195 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
cellular homeostasis GO:0019725 240 0.014
negative regulation of molecular function GO:0044092 258 0.014
response to peptide hormone GO:0043434 127 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
learning or memory GO:0007611 148 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
response to sterol GO:0036314 4 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
sodium ion transport GO:0006814 73 0.013
glucose homeostasis GO:0042593 128 0.013
signal transduction involved in dna damage checkpoint GO:0072422 3 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
response to organonitrogen compound GO:0010243 246 0.013
regulation of t cell anergy GO:0002667 4 0.013
cell junction organization GO:0034330 77 0.013
mapk cascade GO:0000165 281 0.013
regulation of intracellular transport GO:0032386 159 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
skeletal system development GO:0001501 356 0.013
engulfment of apoptotic cell GO:0043652 3 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
muscle adaptation GO:0043500 39 0.012
molting cycle GO:0042303 90 0.012
protein import into nucleus GO:0006606 95 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
alcohol metabolic process GO:0006066 116 0.012
negative regulation of organelle organization GO:0010639 90 0.012
organelle localization GO:0051640 179 0.012
lymphocyte anergy GO:0002249 4 0.012
regulation of secretion GO:0051046 274 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
regulation of response to wounding GO:1903034 189 0.012
small molecule biosynthetic process GO:0044283 132 0.012
protein import GO:0017038 101 0.012
positive regulation of nervous system development GO:0051962 221 0.012
cognition GO:0050890 149 0.012
regionalization GO:0003002 337 0.012
cell junction assembly GO:0034329 52 0.012
spermatid differentiation GO:0048515 115 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
negative regulation of cell activation GO:0050866 111 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
epithelial tube formation GO:0072175 130 0.012
multicellular organism growth GO:0035264 161 0.012
rna 3 end processing GO:0031123 20 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
placenta development GO:0001890 140 0.012
microtubule based process GO:0007017 236 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
regulation of t cell activation GO:0050863 170 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
cellular response to oxidative stress GO:0034599 76 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of inflammatory response GO:0050727 147 0.012
anatomical structure homeostasis GO:0060249 145 0.011
regulation of binding GO:0051098 111 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
receptor mediated endocytosis GO:0006898 51 0.011
muscle cell differentiation GO:0042692 261 0.011
positive regulation of lymphocyte anergy GO:0002913 4 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
camera type eye development GO:0043010 266 0.011
nucleoside metabolic process GO:0009116 246 0.011
cation transport GO:0006812 399 0.011
negative regulation of leukocyte proliferation GO:0070664 46 0.011
ion transmembrane transport GO:0034220 361 0.011
negative regulation of ossification GO:0030279 49 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
regulation of muscle adaptation GO:0043502 31 0.011
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
response to oxygen levels GO:0070482 62 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of neuron death GO:1901214 134 0.011
negative regulation of cell cycle GO:0045786 123 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
urogenital system development GO:0001655 261 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
neuron apoptotic process GO:0051402 142 0.011
t cell anergy GO:0002870 4 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
mrna processing GO:0006397 63 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
coenzyme metabolic process GO:0006732 52 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of secretion by cell GO:1903530 249 0.011
positive regulation of growth GO:0045927 104 0.011
negative regulation of mitotic cell cycle GO:0045930 58 0.011
t cell proliferation GO:0042098 120 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.010
regulation of cell projection organization GO:0031344 206 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
cellular amino acid catabolic process GO:0009063 25 0.010
regulation of myeloid cell differentiation GO:0045637 96 0.010
positive regulation of proteolysis GO:0045862 85 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.010
development of primary sexual characteristics GO:0045137 143 0.010
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
regulation of cellular component size GO:0032535 121 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
protein polyubiquitination GO:0000209 33 0.010
circulatory system process GO:0003013 197 0.010
organic acid catabolic process GO:0016054 51 0.010
response to alcohol GO:0097305 48 0.010
nuclear export GO:0051168 34 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.010
cellular response to hormone stimulus GO:0032870 150 0.010

Eif4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
central nervous system disease DOID:331 0 0.011