Mus musculus

114 known processes

Fxn

frataxin

(Aliases: X25,FA,Frda,FARR)

Fxn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleotide metabolic process GO:0009259 291 0.120
nucleoside phosphate metabolic process GO:0006753 338 0.115
heterocycle catabolic process GO:0046700 280 0.073
ion transmembrane transport GO:0034220 361 0.067
nucleoside monophosphate metabolic process GO:0009123 85 0.065
purine ribonucleoside metabolic process GO:0046128 241 0.061
transmembrane transport GO:0055085 412 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.051
negative regulation of cell cycle GO:0045786 123 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
cellular component assembly involved in morphogenesis GO:0010927 139 0.049
cellular macromolecule catabolic process GO:0044265 206 0.047
cellular lipid metabolic process GO:0044255 323 0.047
organonitrogen compound biosynthetic process GO:1901566 192 0.046
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.045
apoptotic signaling pathway GO:0097190 306 0.038
Human
aromatic compound catabolic process GO:0019439 286 0.038
macromolecule catabolic process GO:0009057 281 0.037
mitochondrion organization GO:0007005 134 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
regulation of cellular amine metabolic process GO:0033238 20 0.036
regulation of organelle organization GO:0033043 289 0.036
Human
germ cell development GO:0007281 185 0.036
mitotic cell cycle GO:0000278 195 0.035
purine nucleoside monophosphate metabolic process GO:0009126 81 0.034
dna metabolic process GO:0006259 303 0.033
nucleocytoplasmic transport GO:0006913 139 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.033
nucleoside catabolic process GO:0009164 206 0.033
cation transport GO:0006812 399 0.032
cellular homeostasis GO:0019725 240 0.031
ribonucleoside metabolic process GO:0009119 245 0.030
glycosyl compound metabolic process GO:1901657 246 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.029
mrna metabolic process GO:0016071 84 0.029
organelle assembly GO:0070925 177 0.029
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.029
rna processing GO:0006396 105 0.028
cation transmembrane transport GO:0098655 266 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
locomotory behavior GO:0007626 195 0.027
nucleotide metabolic process GO:0009117 332 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
regulation of membrane potential GO:0042391 192 0.025
spermatogenesis GO:0007283 284 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
cytoplasmic transport GO:0016482 234 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
male gamete generation GO:0048232 285 0.023
defecation GO:0030421 1 0.023
regulation of cell cycle process GO:0010564 160 0.022
nitrogen compound transport GO:0071705 271 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
peptidyl amino acid modification GO:0018193 336 0.021
regulation of feeding behavior GO:0060259 3 0.021
positive regulation of cell development GO:0010720 237 0.021
histone modification GO:0016570 159 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
dna repair GO:0006281 107 0.020
muscle cell differentiation GO:0042692 261 0.020
regulation of cell cycle GO:0051726 281 0.020
covalent chromatin modification GO:0016569 163 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
positive regulation of protein modification process GO:0031401 299 0.019
mrna processing GO:0006397 63 0.019
amine metabolic process GO:0009308 45 0.019
negative regulation of molecular function GO:0044092 258 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
gland development GO:0048732 330 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
cellular amine metabolic process GO:0044106 44 0.019
cellular ketone metabolic process GO:0042180 84 0.019
rna splicing via transesterification reactions GO:0000375 43 0.019
protein oligomerization GO:0051259 67 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
nucleoside metabolic process GO:0009116 246 0.018
striated muscle myosin thick filament assembly GO:0071688 1 0.018
mitotic cell cycle process GO:1903047 159 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
metal ion homeostasis GO:0055065 189 0.018
cellular response to dna damage stimulus GO:0006974 207 0.017
organophosphate catabolic process GO:0046434 232 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
organelle fission GO:0048285 170 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
feeding behavior GO:0007631 62 0.016
Worm
oxidation reduction process GO:0055114 342 0.015
protein localization to organelle GO:0033365 185 0.015
dna replication GO:0006260 52 0.015
cation homeostasis GO:0055080 212 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
t cell activation GO:0042110 289 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
sensory perception GO:0007600 245 0.014
deoxyribose phosphate catabolic process GO:0046386 4 0.014
deoxyribose phosphate metabolic process GO:0019692 9 0.014
atp metabolic process GO:0046034 75 0.014
regulation of protein localization GO:0032880 231 0.014
cytokine production GO:0001816 319 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
gonad development GO:0008406 141 0.013
myosin filament assembly GO:0031034 2 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
purine containing compound metabolic process GO:0072521 311 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
protein processing GO:0016485 163 0.013
Human
response to oxygen levels GO:0070482 62 0.013
regulation of ran protein signal transduction GO:0032015 3 0.013
cellular amino acid metabolic process GO:0006520 103 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
gtp metabolic process GO:0046039 144 0.013
nucleotide catabolic process GO:0009166 217 0.013
inflammatory response GO:0006954 244 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
lateral inhibition GO:0046331 1 0.013
rna splicing GO:0008380 54 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
purine deoxyribonucleoside triphosphate catabolic process GO:0009217 4 0.012
calcium ion transport GO:0006816 159 0.012
immune effector process GO:0002252 321 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
ras protein signal transduction GO:0007265 77 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
response to oxidative stress GO:0006979 123 0.011
Human Worm
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
cell fate commitment GO:0045165 210 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
protein ubiquitination GO:0016567 171 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
regulation of oxidative phosphorylation GO:0002082 6 0.011
muscle cell development GO:0055001 133 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
leukocyte differentiation GO:0002521 342 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
myosin filament organization GO:0031033 3 0.011
circulatory system process GO:0003013 197 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
cellular protein catabolic process GO:0044257 155 0.010
regulation of atp metabolic process GO:1903578 17 0.010
striated muscle tissue development GO:0014706 293 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
regulation of homeostatic process GO:0032844 182 0.010

Fxn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.080
inherited metabolic disorder DOID:655 0 0.080
central nervous system disease DOID:331 0 0.010
Human
disease of anatomical entity DOID:7 0 0.010
Human
nervous system disease DOID:863 0 0.010
Human