Mus musculus

0 known processes

Hmbs

hydroxymethylbilane synthase

(Aliases: T25658,PBGD,Ups,Uros1)

Hmbs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
porphyrin containing compound metabolic process GO:0006778 22 0.736
organonitrogen compound biosynthetic process GO:1901566 192 0.536
iron sulfur cluster assembly GO:0016226 3 0.454
mitochondrion organization GO:0007005 134 0.440
cofactor metabolic process GO:0051186 80 0.331
cofactor biosynthetic process GO:0051188 41 0.308
mitochondrial transport GO:0006839 36 0.251
meiotic cell cycle process GO:1903046 77 0.153
porphyrin containing compound biosynthetic process GO:0006779 16 0.131
pigment biosynthetic process GO:0046148 26 0.129
tetrapyrrole biosynthetic process GO:0033014 16 0.125
meiosis i GO:0007127 60 0.117
nucleobase containing small molecule metabolic process GO:0055086 352 0.104
carbohydrate derivative biosynthetic process GO:1901137 183 0.103
regulation of lipid metabolic process GO:0019216 118 0.096
spermatogenesis GO:0007283 284 0.094
nucleoside phosphate metabolic process GO:0006753 338 0.092
nucleoside phosphate biosynthetic process GO:1901293 79 0.092
purine containing compound metabolic process GO:0072521 311 0.090
response to oxidative stress GO:0006979 123 0.082
nucleotide metabolic process GO:0009117 332 0.079
nucleoside monophosphate metabolic process GO:0009123 85 0.076
cellular homeostasis GO:0019725 240 0.076
nucleoside triphosphate metabolic process GO:0009141 230 0.071
heme biosynthetic process GO:0006783 12 0.069
ribonucleoside metabolic process GO:0009119 245 0.067
ribose phosphate metabolic process GO:0019693 291 0.067
purine ribonucleotide metabolic process GO:0009150 290 0.066
cellular chemical homeostasis GO:0055082 215 0.064
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.063
gland development GO:0048732 330 0.057
dna dependent dna replication GO:0006261 24 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.055
pigment metabolic process GO:0042440 32 0.055
apoptotic signaling pathway GO:0097190 306 0.054
homeostasis of number of cells GO:0048872 210 0.054
membrane organization GO:0061024 245 0.053
regulation of apoptotic signaling pathway GO:2001233 197 0.049
purine nucleoside metabolic process GO:0042278 241 0.049
regulation of mitochondrion organization GO:0010821 27 0.048
cellular lipid metabolic process GO:0044255 323 0.048
dna metabolic process GO:0006259 303 0.048
positive regulation of mitochondrion organization GO:0010822 17 0.048
nucleoside metabolic process GO:0009116 246 0.048
purine nucleotide metabolic process GO:0006163 302 0.048
t cell activation GO:0042110 289 0.047
macromolecule catabolic process GO:0009057 281 0.047
nucleotide biosynthetic process GO:0009165 78 0.047
cellular metal ion homeostasis GO:0006875 151 0.046
organelle fission GO:0048285 170 0.045
metallo sulfur cluster assembly GO:0031163 3 0.045
spindle assembly involved in female meiosis i GO:0007057 2 0.044
ribonucleotide metabolic process GO:0009259 291 0.043
organophosphate biosynthetic process GO:0090407 122 0.041
meiotic cell cycle GO:0051321 122 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
response to superoxide GO:0000303 16 0.039
cytoplasmic transport GO:0016482 234 0.039
regulation of feeding behavior GO:0060259 3 0.039
dna replication GO:0006260 52 0.039
regulation of lymphocyte activation GO:0051249 240 0.039
organic cyclic compound catabolic process GO:1901361 295 0.038
heme metabolic process GO:0042168 16 0.036
male gamete generation GO:0048232 285 0.036
ion transmembrane transport GO:0034220 361 0.035
protein processing GO:0016485 163 0.035
ribonucleoside monophosphate metabolic process GO:0009161 80 0.034
cellular macromolecule catabolic process GO:0044265 206 0.034
mitochondrial fusion GO:0008053 9 0.034
tetrapyrrole metabolic process GO:0033013 22 0.033
cellular ion homeostasis GO:0006873 165 0.033
heterocycle catabolic process GO:0046700 280 0.033
cellular response to dna damage stimulus GO:0006974 207 0.032
cation transport GO:0006812 399 0.032
protein targeting GO:0006605 143 0.032
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
meiotic nuclear division GO:0007126 115 0.031
apoptotic mitochondrial changes GO:0008637 48 0.030
immune effector process GO:0002252 321 0.030
erythrocyte differentiation GO:0030218 88 0.030
purine ribonucleotide biosynthetic process GO:0009152 59 0.030
cation transmembrane transport GO:0098655 266 0.029
aromatic compound catabolic process GO:0019439 286 0.029
transmembrane transport GO:0055085 412 0.029
cellular ketone metabolic process GO:0042180 84 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
carbohydrate metabolic process GO:0005975 230 0.028
metal ion homeostasis GO:0055065 189 0.027
glycerolipid metabolic process GO:0046486 122 0.027
mitotic cell cycle GO:0000278 195 0.027
mitotic cell cycle process GO:1903047 159 0.026
sensory perception GO:0007600 245 0.026
nuclear division GO:0000280 158 0.025
response to growth factor GO:0070848 198 0.025
cell growth GO:0016049 130 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
response to iron ion GO:0010039 4 0.025
protein catabolic process GO:0030163 221 0.025
sulfur compound metabolic process GO:0006790 100 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
regulation of organelle organization GO:0033043 289 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
leukocyte differentiation GO:0002521 342 0.024
cellular calcium ion homeostasis GO:0006874 119 0.023
amine metabolic process GO:0009308 45 0.023
extracellular structure organization GO:0043062 148 0.023
protein maturation GO:0051604 176 0.023
myeloid cell differentiation GO:0030099 233 0.023
germ cell development GO:0007281 185 0.023
mitochondrial genome maintenance GO:0000002 15 0.022
regulation of cell activation GO:0050865 289 0.022
cell type specific apoptotic process GO:0097285 268 0.022
nitrogen compound transport GO:0071705 271 0.022
cellular amine metabolic process GO:0044106 44 0.022
phospholipid metabolic process GO:0006644 87 0.021
regulation of hydrolase activity GO:0051336 246 0.021
gtp metabolic process GO:0046039 144 0.021
signal transduction in absence of ligand GO:0038034 55 0.020
gonad development GO:0008406 141 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
response to reactive oxygen species GO:0000302 56 0.020
t cell differentiation GO:0030217 174 0.019
response to topologically incorrect protein GO:0035966 25 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
divalent inorganic cation transport GO:0072511 178 0.019
calcium ion homeostasis GO:0055074 127 0.019
atp metabolic process GO:0046034 75 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
nucleoside catabolic process GO:0009164 206 0.019
cation homeostasis GO:0055080 212 0.019
cytokine production GO:0001816 319 0.019
oxidation reduction process GO:0055114 342 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
intracellular protein transport GO:0006886 204 0.018
positive regulation of protein modification process GO:0031401 299 0.018
leukocyte mediated immunity GO:0002443 174 0.018
negative regulation of organelle organization GO:0010639 90 0.018
organelle assembly GO:0070925 177 0.018
development of primary sexual characteristics GO:0045137 143 0.018
inflammatory response GO:0006954 244 0.018
peptidyl amino acid modification GO:0018193 336 0.018
microtubule based process GO:0007017 236 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
endocytosis GO:0006897 168 0.017
dna recombination GO:0006310 92 0.017
lymphocyte differentiation GO:0030098 242 0.017
regulation of membrane potential GO:0042391 192 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
anatomical structure homeostasis GO:0060249 145 0.017
positive regulation of transferase activity GO:0051347 167 0.017
purine nucleotide biosynthetic process GO:0006164 65 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
regulation of cell cycle GO:0051726 281 0.017
response to inorganic substance GO:0010035 96 0.017
mitochondrial membrane organization GO:0007006 26 0.017
response to unfolded protein GO:0006986 21 0.016
cellular amino acid metabolic process GO:0006520 103 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
negative regulation of molecular function GO:0044092 258 0.016
transition metal ion homeostasis GO:0055076 54 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
multicellular organism growth GO:0035264 161 0.016
positive regulation of growth GO:0045927 104 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
negative regulation of immune system process GO:0002683 209 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
calcium ion transport GO:0006816 159 0.015
extracellular matrix organization GO:0030198 147 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
divalent metal ion transport GO:0070838 172 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
alcohol metabolic process GO:0006066 116 0.015
amide transport GO:0042886 138 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
activation of immune response GO:0002253 138 0.015
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
feeding behavior GO:0007631 62 0.015
cellular response to oxidative stress GO:0034599 76 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
response to oxygen radical GO:0000305 16 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
locomotory behavior GO:0007626 195 0.014
renal system development GO:0072001 225 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
cellular transition metal ion homeostasis GO:0046916 32 0.014
cd4 positive alpha beta t cell activation GO:0035710 45 0.014
positive regulation of lipid metabolic process GO:0045834 40 0.014
organ growth GO:0035265 117 0.014
immune response activating signal transduction GO:0002757 116 0.014
ribose phosphate biosynthetic process GO:0046390 59 0.014
multi multicellular organism process GO:0044706 109 0.014
liver development GO:0001889 66 0.014
gtp catabolic process GO:0006184 143 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
membrane fusion GO:0061025 38 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.014
regulation of cellular response to stress GO:0080135 159 0.014
purine containing compound biosynthetic process GO:0072522 70 0.013
positive regulation of cell growth GO:0030307 33 0.013
defecation GO:0030421 1 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of mitochondrial membrane permeability GO:0046902 17 0.013
positive regulation of cell death GO:0010942 224 0.013
response to oxygen levels GO:0070482 62 0.013
cellular protein complex assembly GO:0043623 116 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
protein ubiquitination GO:0016567 171 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
nucleoside monophosphate biosynthetic process GO:0009124 12 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
skeletal system development GO:0001501 356 0.012
regulation of glycogen catabolic process GO:0005981 2 0.012
neuromuscular process GO:0050905 99 0.012
purine nucleoside biosynthetic process GO:0042451 19 0.012
iron ion homeostasis GO:0055072 36 0.012
cellular response to topologically incorrect protein GO:0035967 25 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
t cell receptor signaling pathway GO:0050852 46 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
t cell proliferation GO:0042098 120 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
epithelial cell proliferation GO:0050673 174 0.012
mrna metabolic process GO:0016071 84 0.012
organelle fusion GO:0048284 28 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
regulation of t cell activation GO:0050863 170 0.011
rna processing GO:0006396 105 0.011
single organism nuclear import GO:1902593 95 0.011
ras protein signal transduction GO:0007265 77 0.011
regulation of ion transport GO:0043269 215 0.011
regulation of intracellular transport GO:0032386 159 0.011
lung development GO:0030324 164 0.011
regulation of cellular amino acid metabolic process GO:0006521 5 0.011
regulation of homeostatic process GO:0032844 182 0.011
regulation of inflammatory response GO:0050727 147 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.011
mitochondrial protein processing GO:0034982 5 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
purine containing compound catabolic process GO:0072523 213 0.011
regulation of cell growth GO:0001558 91 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
anion transport GO:0006820 177 0.011
carbohydrate homeostasis GO:0033500 128 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of mapk cascade GO:0043408 248 0.011
cellular protein catabolic process GO:0044257 155 0.011
regulation of neuron differentiation GO:0045664 281 0.011
regulation of defense response GO:0031347 233 0.011
lymphocyte proliferation GO:0046651 164 0.011
blood circulation GO:0008015 195 0.011
wnt signaling pathway GO:0016055 188 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
microtubule nucleation GO:0007020 2 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
myeloid cell homeostasis GO:0002262 114 0.011
purine deoxyribonucleoside triphosphate metabolic process GO:0009215 7 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
mitotic nuclear division GO:0007067 48 0.011
response to lipopolysaccharide GO:0032496 128 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
alpha beta t cell activation GO:0046631 91 0.010
dephosphorylation GO:0016311 129 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
deoxyribonucleotide metabolic process GO:0009262 14 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
deoxyribose phosphate metabolic process GO:0019692 9 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
adult behavior GO:0030534 135 0.010
camera type eye development GO:0043010 266 0.010
regulation of dna dependent dna replication GO:0090329 8 0.010
mitochondrial dna replication GO:0006264 7 0.010
wound healing GO:0042060 157 0.010
muscle cell differentiation GO:0042692 261 0.010
positive regulation of metalloenzyme activity GO:0048554 3 0.010
circulatory system process GO:0003013 197 0.010
respiratory tube development GO:0030323 167 0.010

Hmbs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.016
disease of metabolism DOID:0014667 0 0.015
Human
inherited metabolic disorder DOID:655 0 0.015
Human