Mus musculus

26 known processes

Gdf1

growth differentiation factor 1

(Aliases: Gdf-1,AI385651)

Gdf1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mesendoderm development GO:0048382 3 0.981
cellular response to growth factor stimulus GO:0071363 197 0.952
Mouse
endocrine system development GO:0035270 98 0.924
Mouse
lung development GO:0030324 164 0.921
Mouse
floor plate morphogenesis GO:0033505 3 0.858
respiratory tube development GO:0030323 167 0.825
Mouse
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.800
response to growth factor GO:0070848 198 0.781
Mouse
muscle tissue development GO:0060537 308 0.779
Mouse
axial mesodermal cell fate commitment GO:0048322 1 0.757
left lung morphogenesis GO:0060460 3 0.748
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.747
gland development GO:0048732 330 0.735
Mouse Fly
regionalization GO:0003002 337 0.734
Mouse Fly
respiratory system development GO:0060541 190 0.713
Mouse Fly
heart morphogenesis GO:0003007 178 0.713
Mouse
bmp signaling pathway GO:0030509 93 0.702
Mouse Fly
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.697
axial mesodermal cell fate specification GO:0048327 1 0.677
tendon formation GO:0035992 4 0.655
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.614
Mouse Fly
positive regulation of cell migration GO:0030335 109 0.602
Mouse
activin receptor signaling pathway GO:0032924 18 0.599
ventral midline development GO:0007418 4 0.593
specification of organ position GO:0010159 3 0.591
Mouse
skeletal system development GO:0001501 356 0.590
Mouse
somitogenesis GO:0001756 69 0.589
Mouse
embryonic skeletal system development GO:0048706 120 0.588
Mouse
morphogenesis of a branching structure GO:0001763 203 0.575
Mouse
lung morphogenesis GO:0060425 50 0.572
Mouse
bone development GO:0060348 120 0.571
Mouse
ureteric bud morphogenesis GO:0060675 62 0.567
Mouse
striated muscle tissue development GO:0014706 293 0.559
Mouse
stem cell development GO:0048864 219 0.553
Mouse Fly
proteoglycan metabolic process GO:0006029 38 0.530
Mouse
blood vessel morphogenesis GO:0048514 285 0.495
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.473
Mouse
formation of primary germ layer GO:0001704 77 0.461
Mouse
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.450
determination of left right symmetry GO:0007368 80 0.438
chondrocyte differentiation GO:0002062 72 0.417
Mouse
digestive tract development GO:0048565 190 0.412
Mouse Fly
morphogenesis of an epithelial bud GO:0060572 18 0.405
Mouse
axial mesoderm development GO:0048318 8 0.387
mesoderm development GO:0007498 100 0.376
skeletal system morphogenesis GO:0048705 203 0.372
Mouse
inflammatory response GO:0006954 244 0.370
Mouse
oocyte construction GO:0007308 2 0.367
Fly
digestive tract morphogenesis GO:0048546 147 0.360
Mouse Fly
camera type eye development GO:0043010 266 0.357
Mouse
embryonic organ morphogenesis GO:0048562 276 0.354
Mouse
positive regulation of chemotaxis GO:0050921 38 0.348
cardiac muscle cell differentiation GO:0055007 69 0.345
regulation of cellular response to growth factor stimulus GO:0090287 82 0.345
negative regulation of prostatic bud formation GO:0060686 4 0.344
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.343
Mouse
embryonic heart tube development GO:0035050 65 0.330
Mouse
germ cell development GO:0007281 185 0.323
Mouse Fly
positive regulation of mapk cascade GO:0043410 170 0.315
Mouse
left lung development GO:0060459 4 0.295
determination of left right asymmetry in nervous system GO:0035545 1 0.292
cardiac muscle tissue development GO:0048738 130 0.288
Mouse
positive regulation of cell development GO:0010720 237 0.286
Mouse
mapk cascade GO:0000165 281 0.282
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.280
telencephalon development GO:0021537 186 0.276
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.273
embryonic limb morphogenesis GO:0030326 126 0.271
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.270
Mouse Fly
embryonic skeletal joint development GO:0072498 13 0.269
Mouse
neural tube development GO:0021915 160 0.263
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.262
Mouse
spleen development GO:0048536 39 0.257
embryonic heart tube morphogenesis GO:0003143 51 0.253
muscle fiber development GO:0048747 76 0.246
Mouse
regulation of cell motility GO:2000145 236 0.246
Mouse
connective tissue development GO:0061448 179 0.243
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.239
Mouse Fly
forebrain development GO:0030900 302 0.236
Mouse
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.235
skeletal muscle fiber development GO:0048741 58 0.231
Mouse
gastrulation GO:0007369 116 0.230
Mouse
pituitary gland development GO:0021983 38 0.226
Mouse
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 2 0.213
nodal signaling pathway GO:0038092 10 0.213
muscle cell differentiation GO:0042692 261 0.208
Mouse
maintenance of location GO:0051235 89 0.202
adenohypophysis development GO:0021984 14 0.201
Mouse
chemotaxis GO:0006935 247 0.201
Fly
sensory organ morphogenesis GO:0090596 242 0.200
Mouse Fly
cardiac septum development GO:0003279 59 0.196
regulation of ion transport GO:0043269 215 0.192
axial mesoderm formation GO:0048320 3 0.188
positive regulation of protein modification process GO:0031401 299 0.187
Mouse
cartilage development GO:0051216 140 0.185
Mouse
epithelial tube morphogenesis GO:0060562 303 0.179
Mouse Fly
kidney mesenchyme morphogenesis GO:0072131 4 0.179
renal system process GO:0003014 48 0.178
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.168
hepaticobiliary system development GO:0061008 67 0.168
branching involved in ureteric bud morphogenesis GO:0001658 56 0.165
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.165
Mouse
endoderm development GO:0007492 45 0.164
striated muscle cell development GO:0055002 125 0.161
Mouse
positive regulation of cell death GO:0010942 224 0.161
regulation of cell migration GO:0030334 219 0.160
Mouse
mesoderm morphogenesis GO:0048332 64 0.158
Mouse
cation transport GO:0006812 399 0.158
appendage morphogenesis GO:0035107 149 0.157
Mouse Fly
digestive system development GO:0055123 200 0.156
Mouse Fly
kidney development GO:0001822 213 0.156
Mouse
mesenchymal cell proliferation GO:0010463 44 0.156
Mouse
hindlimb morphogenesis GO:0035137 42 0.155
Mouse
induction of positive chemotaxis GO:0050930 7 0.154
establishment of protein localization to organelle GO:0072594 118 0.152
determination of heart left right asymmetry GO:0061371 48 0.150
neural tube patterning GO:0021532 43 0.148
Mouse
smad protein signal transduction GO:0060395 21 0.148
Mouse
cation transmembrane transport GO:0098655 266 0.148
muscle contraction GO:0006936 101 0.147
dorsal ventral neural tube patterning GO:0021904 28 0.147
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.147
Mouse
positive regulation of programmed cell death GO:0043068 218 0.146
positive regulation of dna endoreduplication GO:0032877 2 0.144
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.142
regulation of myoblast differentiation GO:0045661 29 0.142
Mouse
circulatory system process GO:0003013 197 0.142
fat cell differentiation GO:0045444 160 0.141
Mouse
response to organic cyclic compound GO:0014070 198 0.139
Mouse
cell adhesion GO:0007155 329 0.139
heart contraction GO:0060047 93 0.138
apoptotic signaling pathway GO:0097190 306 0.138
corticotropin hormone secreting cell differentiation GO:0060128 3 0.137
Mouse
regulation of system process GO:0044057 200 0.137
mesonephric epithelium development GO:0072163 94 0.137
Mouse
regulation of myotube differentiation GO:0010830 62 0.136
Mouse
regulation of fibroblast proliferation GO:0048145 34 0.136
cell type specific apoptotic process GO:0097285 268 0.135
regulation of osteoblast differentiation GO:0045667 67 0.134
Mouse
positive regulation of cytoplasmic transport GO:1903651 40 0.134
notochord development GO:0030903 20 0.133
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.133
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.133
regulation of apoptotic signaling pathway GO:2001233 197 0.133
nephron tubule morphogenesis GO:0072078 68 0.132
Mouse
monosaccharide metabolic process GO:0005996 106 0.131
positive regulation of behavior GO:0048520 40 0.128
erythrocyte differentiation GO:0030218 88 0.127
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.125
Mouse
carbohydrate metabolic process GO:0005975 230 0.124
branching morphogenesis of an epithelial tube GO:0048754 159 0.123
Mouse
muscle system process GO:0003012 141 0.123
regulation of receptor activity GO:0010469 41 0.121
atrioventricular valve morphogenesis GO:0003181 13 0.120
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.120
Mouse
divalent metal ion transport GO:0070838 172 0.119
cell matrix adhesion GO:0007160 68 0.117
retina development in camera type eye GO:0060041 119 0.117
regulation of activin receptor signaling pathway GO:0032925 10 0.117
regulation of muscle system process GO:0090257 80 0.116
epithelial cell differentiation involved in kidney development GO:0035850 23 0.116
Mouse
regulation of vasculature development GO:1901342 88 0.116
positive regulation of tendon cell differentiation GO:2001051 1 0.115
neural tube closure GO:0001843 90 0.113
Mouse
limb development GO:0060173 166 0.113
Mouse
regulation of endothelial cell differentiation GO:0045601 10 0.112
Mouse
somite rostral caudal axis specification GO:0032525 13 0.112
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.112
Mouse
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.112
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.111
cellular ketone metabolic process GO:0042180 84 0.111
regulation of positive chemotaxis GO:0050926 7 0.111
ossification GO:0001503 216 0.109
Mouse
ion transmembrane transport GO:0034220 361 0.109
myotube cell development GO:0014904 60 0.107
Mouse
cellular chemical homeostasis GO:0055082 215 0.106
divalent inorganic cation transport GO:0072511 178 0.106
myotube differentiation GO:0014902 105 0.106
Mouse
epithelial mesenchymal cell signaling GO:0060684 7 0.104
Mouse
nephrogenic mesenchyme development GO:0072076 3 0.104
neuroepithelial cell differentiation GO:0060563 37 0.104
Mouse
negative regulation of stem cell maintenance GO:1902455 4 0.104
diencephalon development GO:0021536 63 0.104
Mouse
response to oxygen levels GO:0070482 62 0.102
Mouse
morphogenesis of an epithelial fold GO:0060571 28 0.101
Mouse
stem cell division GO:0017145 30 0.101
Fly
embryonic axis specification GO:0000578 30 0.101
Mouse Fly
prostatic bud formation GO:0060513 10 0.100
Mouse
cell fate determination GO:0001709 32 0.100
Mouse
cytoplasmic transport GO:0016482 234 0.098
oxidation reduction process GO:0055114 342 0.097
Mouse
regulation of stem cell differentiation GO:2000736 50 0.097
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.097
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.096
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.096
prechordal plate formation GO:0021501 1 0.096
muscle cell development GO:0055001 133 0.095
Mouse
nitrogen compound transport GO:0071705 271 0.095
epithelial cell proliferation GO:0050673 174 0.095
Mouse
segmentation GO:0035282 93 0.095
Mouse
regulation of cell activation GO:0050865 289 0.093
positive regulation of cell activation GO:0050867 158 0.093
t cell activation GO:0042110 289 0.092
epithelial to mesenchymal transition GO:0001837 47 0.092
Mouse
amine metabolic process GO:0009308 45 0.091
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.091
roof plate formation GO:0021509 1 0.090
neuron projection guidance GO:0097485 141 0.090
negative regulation of cell migration GO:0030336 59 0.089
protein targeting GO:0006605 143 0.088
lipid localization GO:0010876 126 0.088
regulation of neuron differentiation GO:0045664 281 0.087
Mouse
single organismal cell cell adhesion GO:0016337 131 0.086
homeostasis of number of cells GO:0048872 210 0.085
Mouse
mesenchyme development GO:0060485 152 0.085
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.085
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.085
Mouse
glycoprotein metabolic process GO:0009100 116 0.085
Mouse
mesodermal cell differentiation GO:0048333 22 0.085
Mouse
lens morphogenesis in camera type eye GO:0002089 24 0.084
Mouse
oogenesis GO:0048477 56 0.082
Fly
regulation of reproductive process GO:2000241 66 0.082
Mouse
endothelium development GO:0003158 45 0.082
Mouse
axial mesodermal cell differentiation GO:0048321 1 0.082
insulin secretion GO:0030073 89 0.081
hypothalamus development GO:0021854 16 0.081
embryonic skeletal joint morphogenesis GO:0060272 11 0.080
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.080
positive regulation of intracellular transport GO:0032388 70 0.080
appendage development GO:0048736 166 0.079
Mouse Fly
endothelial cell differentiation GO:0045446 41 0.079
Mouse
mesonephric tubule morphogenesis GO:0072171 63 0.079
Mouse
nephron morphogenesis GO:0072028 69 0.077
Mouse
transmembrane transport GO:0055085 412 0.077
cell maturation GO:0048469 127 0.076
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.076
dna endoreduplication GO:0042023 4 0.076
regulation of branching involved in prostate gland morphogenesis GO:0060687 7 0.076
Mouse
response to organonitrogen compound GO:0010243 246 0.076
glomerulus development GO:0032835 40 0.075
Mouse
regulation of kinase activity GO:0043549 249 0.075
formation of anatomical boundary GO:0048859 6 0.075
Mouse
protein maturation GO:0051604 176 0.074
dna metabolic process GO:0006259 303 0.073
erk1 and erk2 cascade GO:0070371 77 0.073
Mouse
cardiac septum morphogenesis GO:0060411 46 0.072
positive regulation of activin receptor signaling pathway GO:0032927 3 0.072
regulation of cartilage development GO:0061035 44 0.072
Mouse
regulation of cell adhesion GO:0030155 154 0.071
regulation of muscle tissue development GO:1901861 97 0.070
Mouse
cellular amino acid metabolic process GO:0006520 103 0.070
multicellular organismal homeostasis GO:0048871 164 0.070
liver development GO:0001889 66 0.069
regulation of angiogenesis GO:0045765 81 0.069
prostate gland development GO:0030850 48 0.069
Mouse
glomerular epithelium development GO:0072010 11 0.068
Mouse
peptidyl amino acid modification GO:0018193 336 0.067
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.067
endochondral bone morphogenesis GO:0060350 50 0.067
Mouse
regulation of timing of cell differentiation GO:0048505 11 0.066
negative regulation of neuron apoptotic process GO:0043524 92 0.066
angiogenesis GO:0001525 201 0.066
Mouse
neuroendocrine cell differentiation GO:0061101 7 0.066
Mouse
cell substrate adhesion GO:0031589 130 0.065
cell cell signaling involved in cell fate commitment GO:0045168 35 0.065
Mouse
positive regulation of cell adhesion GO:0045785 80 0.065
protein processing GO:0016485 163 0.065
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.065
Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.064
glomerular epithelial cell development GO:0072310 6 0.064
Mouse
leukocyte differentiation GO:0002521 342 0.064
striated muscle cell proliferation GO:0014855 39 0.064
limbic system development GO:0021761 72 0.063
regulation of secretion GO:0051046 274 0.063
positive regulation of nervous system development GO:0051962 221 0.063
Mouse
metanephric mesenchyme morphogenesis GO:0072133 4 0.062
ear development GO:0043583 200 0.062
Mouse
molting cycle GO:0042303 90 0.062
notch signaling pathway GO:0007219 71 0.062
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.061
Mouse
regulation of tendon cell differentiation GO:2001049 1 0.061
fibroblast proliferation GO:0048144 35 0.061
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.061
regulation of astrocyte differentiation GO:0048710 20 0.061
Mouse
regulation of protein localization GO:0032880 231 0.061
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.060
regulation of chemotaxis GO:0050920 53 0.060
heart trabecula formation GO:0060347 14 0.060
prostate gland morphogenesis GO:0060512 32 0.060
Mouse
peptidyl serine modification GO:0018209 83 0.059
rhythmic process GO:0048511 174 0.059
kidney epithelium development GO:0072073 121 0.059
Mouse
regulation of protein targeting GO:1903533 61 0.059
regulation of chondrocyte differentiation GO:0032330 33 0.058
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.058
Mouse
regulation of metal ion transport GO:0010959 106 0.058
determination of digestive tract left right asymmetry GO:0071907 1 0.058
blood circulation GO:0008015 195 0.058
oocyte differentiation GO:0009994 35 0.057
Fly
muscle cell proliferation GO:0033002 52 0.057
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.057
branch elongation of an epithelium GO:0060602 19 0.057
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.056
Mouse
mitotic cell cycle GO:0000278 195 0.056
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.055
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.055
mesenchymal cell development GO:0014031 93 0.054
Mouse
kidney mesenchymal cell proliferation GO:0072135 2 0.054
regulation of erk1 and erk2 cascade GO:0070372 71 0.054
Mouse
multicellular organism growth GO:0035264 161 0.054
cellular lipid metabolic process GO:0044255 323 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.054
regulation of wnt signaling pathway GO:0030111 123 0.053
Mouse
response to extracellular stimulus GO:0009991 127 0.053
Mouse
anterior posterior axis specification embryo GO:0008595 9 0.053
heart trabecula morphogenesis GO:0061384 26 0.053
positive regulation of fibroblast proliferation GO:0048146 20 0.053
tube closure GO:0060606 91 0.053
Mouse
positive regulation of ion transport GO:0043270 65 0.053
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.053
Mouse
stem cell proliferation GO:0072089 117 0.052
Mouse
positive regulation of angiogenesis GO:0045766 46 0.052
regulation of prostatic bud formation GO:0060685 6 0.052
Mouse
epithelial tube formation GO:0072175 130 0.052
Mouse
floor plate formation GO:0021508 2 0.051
multi multicellular organism process GO:0044706 109 0.051
trachea formation GO:0060440 3 0.051
Mouse
locomotory behavior GO:0007626 195 0.051
lipid storage GO:0019915 36 0.051
myoblast differentiation GO:0045445 52 0.051
Mouse
spemann organizer formation GO:0060061 2 0.051
response to acid chemical GO:0001101 111 0.050
developmental maturation GO:0021700 193 0.050
Fly
bone morphogenesis GO:0060349 78 0.050
Mouse
negative regulation of nervous system development GO:0051961 156 0.050
inhibition of neuroepithelial cell differentiation GO:0002085 2 0.050
adult locomotory behavior GO:0008344 91 0.050
positive regulation of protein kinase activity GO:0045860 144 0.050
cranial suture morphogenesis GO:0060363 8 0.049
Mouse
regulation of cellular catabolic process GO:0031329 242 0.049
positive regulation of apoptotic signaling pathway GO:2001235 95 0.049
regulation of secretion by cell GO:1903530 249 0.049
trophectodermal cellular morphogenesis GO:0001831 3 0.048
positive regulation of kinase activity GO:0033674 155 0.048
cellular response to peptide hormone stimulus GO:0071375 92 0.048
positive regulation of stem cell proliferation GO:2000648 59 0.048
negative regulation of neuron death GO:1901215 98 0.048
mesenchymal cell differentiation GO:0048762 107 0.048
Mouse
blastoderm segmentation GO:0007350 13 0.048
regulation of protein serine threonine kinase activity GO:0071900 157 0.048
cell cycle switching GO:0060184 1 0.047
organic acid transport GO:0015849 101 0.047
embryonic hindlimb morphogenesis GO:0035116 32 0.047
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.047
purine nucleotide metabolic process GO:0006163 302 0.047
cell division GO:0051301 120 0.046
Fly
regulation of ossification GO:0030278 112 0.046
Mouse
positive regulation of transferase activity GO:0051347 167 0.046
positive regulation of growth GO:0045927 104 0.046
microtubule based process GO:0007017 236 0.046
axon guidance GO:0007411 141 0.045
polarity specification of proximal distal axis GO:0010085 2 0.045
cell differentiation involved in kidney development GO:0061005 33 0.045
Mouse
cardiocyte differentiation GO:0035051 87 0.045
Fly
epithelial cell development GO:0002064 159 0.045
Mouse Fly
regulation of protein kinase activity GO:0045859 232 0.044
ureteric bud development GO:0001657 94 0.044
Mouse
regulation of organ morphogenesis GO:2000027 144 0.044
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.044
metanephros development GO:0001656 79 0.044
Mouse
positive regulation of cell substrate adhesion GO:0010811 47 0.043
floor plate development GO:0033504 7 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
ribonucleotide catabolic process GO:0009261 208 0.043
circadian rhythm GO:0007623 114 0.043
positive regulation of fat cell differentiation GO:0045600 32 0.043
Mouse
regulation of transferase activity GO:0051338 263 0.043
response to amino acid GO:0043200 37 0.043
spermatogenesis GO:0007283 284 0.042
regulation of fat cell differentiation GO:0045598 81 0.042
Mouse
kidney vasculature development GO:0061440 15 0.042
Mouse
response to nutrient levels GO:0031667 109 0.042
Mouse
t cell differentiation GO:0030217 174 0.042
glycosylation GO:0070085 62 0.042
response to decreased oxygen levels GO:0036293 59 0.041
Mouse
cardiac muscle tissue growth GO:0055017 37 0.041
calcium ion transmembrane transport GO:0070588 85 0.041
cardiac chamber development GO:0003205 108 0.041
kidney morphogenesis GO:0060993 83 0.041
Mouse
oocyte axis specification GO:0007309 2 0.041
Fly
renal system development GO:0072001 225 0.041
Mouse Fly
coagulation GO:0050817 78 0.041
protein kinase b signaling GO:0043491 74 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
negative regulation of embryonic development GO:0045992 22 0.040
Mouse
response to transforming growth factor beta GO:0071559 88 0.040
positive regulation of immune effector process GO:0002699 107 0.040
intracellular receptor signaling pathway GO:0030522 74 0.040
regulation of neuron projection development GO:0010975 169 0.040
hematopoietic progenitor cell differentiation GO:0002244 143 0.040
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.039
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.039
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.039
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.039
protein localization to nucleus GO:0034504 121 0.039
positive regulation of cell cycle GO:0045787 92 0.039
protein localization to organelle GO:0033365 185 0.039
negative regulation of phosphate metabolic process GO:0045936 184 0.039
male gamete generation GO:0048232 285 0.039
cellular homeostasis GO:0019725 240 0.039
regulation of skeletal muscle fiber development GO:0048742 36 0.039
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.039
Mouse
positive regulation of cell motility GO:2000147 116 0.039
Mouse
myeloid cell differentiation GO:0030099 233 0.039
Mouse
male sex differentiation GO:0046661 109 0.039
striated muscle contraction GO:0006941 45 0.038
cardiac ventricle morphogenesis GO:0003208 50 0.038
tendon cell differentiation GO:0035990 4 0.038
Mouse
developmental induction GO:0031128 34 0.038
Mouse
cardiac muscle cell development GO:0055013 39 0.038
mesonephros development GO:0001823 97 0.038
Mouse
regulation of smoothened signaling pathway GO:0008589 58 0.038
cerebral cortex development GO:0021987 86 0.038
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.038
positive regulation of heart growth GO:0060421 18 0.037
heart growth GO:0060419 45 0.037
regulation of t cell activation GO:0050863 170 0.037
regulation of cytoplasmic transport GO:1903649 112 0.037
regulation of ion transmembrane transporter activity GO:0032412 54 0.037
calcium ion transport GO:0006816 159 0.037
positive regulation of endothelial cell proliferation GO:0001938 17 0.037
Mouse
hexose metabolic process GO:0019318 98 0.036
positive regulation of glial cell differentiation GO:0045687 21 0.035
Mouse
positive regulation of intracellular protein transport GO:0090316 42 0.035
smoothened signaling pathway GO:0007224 105 0.035
heart valve morphogenesis GO:0003179 21 0.035
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.035
Mouse
calcium mediated signaling GO:0019722 46 0.035
inorganic ion transmembrane transport GO:0098660 234 0.034
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.034
mammary gland morphogenesis GO:0060443 54 0.034
Mouse
positive regulation of protein kinase b signaling GO:0051897 32 0.034
membrane lipid metabolic process GO:0006643 53 0.034
cellular response to dna damage stimulus GO:0006974 207 0.034
leukocyte migration GO:0050900 124 0.034
positive regulation of ossification GO:0045778 47 0.034
Mouse
tissue remodeling GO:0048771 102 0.034
nephron development GO:0072006 109 0.034
Mouse
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.033
Mouse
regulation of intracellular transport GO:0032386 159 0.033
energy derivation by oxidation of organic compounds GO:0015980 77 0.033
membrane organization GO:0061024 245 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
myeloid cell homeostasis GO:0002262 114 0.033
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.033
anion transmembrane transport GO:0098656 71 0.033
developmental growth involved in morphogenesis GO:0060560 138 0.033
Mouse
protein glycosylation GO:0006486 55 0.033
negative regulation of cell motility GO:2000146 61 0.032
positive regulation of osteoblast differentiation GO:0045669 34 0.032
Mouse
regulation of dna endoreduplication GO:0032875 3 0.032
regulation of intracellular protein transport GO:0033157 82 0.032
tube formation GO:0035148 140 0.032
Mouse
mesoderm formation GO:0001707 62 0.032
Mouse
macromolecule catabolic process GO:0009057 281 0.032
negative regulation of myoblast differentiation GO:0045662 18 0.032
Mouse
glucose metabolic process GO:0006006 92 0.032
glucose homeostasis GO:0042593 128 0.032
neural tube formation GO:0001841 108 0.032
Mouse
cellular response to peptide GO:1901653 92 0.031
ameboidal type cell migration GO:0001667 128 0.031
Fly
kidney mesenchyme development GO:0072074 14 0.031
Mouse
adult walking behavior GO:0007628 41 0.031
nucleoside catabolic process GO:0009164 206 0.031
regulation of glial cell differentiation GO:0045685 41 0.031
Mouse
aromatic compound catabolic process GO:0019439 286 0.031
nucleoside metabolic process GO:0009116 246 0.031
carbohydrate biosynthetic process GO:0016051 74 0.031
regulation of neuron apoptotic process GO:0043523 122 0.031
dna repair GO:0006281 107 0.031
regulation of cell cycle process GO:0010564 160 0.031
stem cell maintenance GO:0019827 130 0.031
Fly
defense response to gram positive bacterium GO:0050830 50 0.030
regulation of nucleocytoplasmic transport GO:0046822 73 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.030
response to radiation GO:0009314 165 0.030
regulation of carbohydrate metabolic process GO:0006109 75 0.030
negative regulation of protein modification process GO:0031400 163 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.030
lymphocyte mediated immunity GO:0002449 139 0.030
negative regulation of cell development GO:0010721 169 0.030
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.030

Gdf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.084
Human
nervous system disease DOID:863 0 0.084
central nervous system disease DOID:331 0 0.035
neurodegenerative disease DOID:1289 0 0.035