Mus musculus

73 known processes

H2-K1

histocompatibility 2, K1, K region

(Aliases: K-f,H-2K,H-2K(d),MGC7052,H2-K,MGC184092)

H2-K1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of t cell mediated cytotoxicity GO:0001916 15 1.000
regulation of t cell mediated cytotoxicity GO:0001914 18 1.000
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 1.000
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 1.000
negative regulation of natural killer cell mediated immunity GO:0002716 5 1.000
Rat
regulation of leukocyte mediated cytotoxicity GO:0001910 38 1.000
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 5 1.000
Mouse
antigen processing and presentation via mhc class ib GO:0002475 8 0.999
Mouse
natural killer cell mediated cytotoxicity GO:0042267 29 0.999
Mouse Rat
iron ion import into cell GO:0097459 4 0.999
Mouse
t cell mediated cytotoxicity GO:0001913 26 0.999
regulation of cell killing GO:0031341 40 0.998
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.998
regulation of natural killer cell mediated immunity GO:0002715 19 0.995
Mouse Rat
t cell mediated immunity GO:0002456 50 0.994
import into cell GO:0098657 8 0.994
Mouse
antigen processing and presentation of exogenous peptide antigen via mhc class ib GO:0002477 3 0.994
Mouse
positive regulation of cell killing GO:0031343 33 0.993
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.992
Rat
antigen processing and presentation GO:0019882 47 0.991
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.986
Mouse Rat
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.970
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.967
regulation of t cell mediated immunity GO:0002709 34 0.951
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 3 0.931
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.926
reactive nitrogen species metabolic process GO:2001057 0 0.924
regulation of adaptive immune response GO:0002819 90 0.905
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.903
antigen processing and presentation of exogenous antigen GO:0019884 26 0.902
regulation of defense response GO:0031347 233 0.893
Mouse Rat
multicellular organismal iron ion homeostasis GO:0060586 8 0.893
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.891
iron ion homeostasis GO:0055072 36 0.887
Mouse
antigen processing and presentation of peptide antigen GO:0048002 29 0.867
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.867
leukocyte mediated immunity GO:0002443 174 0.862
innate immune response GO:0045087 157 0.856
Mouse Rat
antigen processing and presentation of exogenous protein antigen via mhc class ib tap dependent GO:0002481 3 0.855
Mouse
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap dependent GO:0002485 3 0.851
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.850
adaptive immune response GO:0002250 155 0.849
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.840
reactive oxygen species biosynthetic process GO:1903409 8 0.839
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.824
regulation of leukocyte mediated immunity GO:0002703 104 0.817
response to molecule of bacterial origin GO:0002237 143 0.798
Mouse
natural killer cell mediated immunity GO:0002228 29 0.797
Mouse Rat
regulation of reactive oxygen species metabolic process GO:2000377 40 0.777
positive regulation of t cell mediated immunity GO:0002711 24 0.753
lymphocyte mediated immunity GO:0002449 139 0.745
nitric oxide metabolic process GO:0046209 25 0.718
Mouse
cell killing GO:0001906 67 0.716
positive regulation of defense response GO:0031349 124 0.703
Mouse
positive regulation of immune effector process GO:0002699 107 0.687
lymphocyte activation involved in immune response GO:0002285 93 0.683
Mouse
defense response to other organism GO:0098542 197 0.668
antigen processing and presentation of endogenous antigen GO:0019883 6 0.667
regulation of interferon gamma production GO:0032649 57 0.663
Mouse
alpha beta t cell activation GO:0046631 91 0.662
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.646
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.645
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.630
Mouse
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.609
defense response to bacterium GO:0042742 119 0.578
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.568
t cell activation GO:0042110 289 0.567
Mouse
cytokine production GO:0001816 319 0.560
Mouse
regulation of innate immune response GO:0045088 91 0.547
Mouse Rat
interleukin 1 beta production GO:0032611 30 0.539
Mouse
hormone biosynthetic process GO:0042446 16 0.525
Mouse
tolerance induction dependent upon immune response GO:0002461 1 0.522
Rat
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.519
immune effector process GO:0002252 321 0.516
positive regulation of adaptive immune response GO:0002821 61 0.514
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.508
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.499
t cell differentiation in thymus GO:0033077 77 0.490
cytokine production involved in immune response GO:0002367 34 0.460
Mouse
cation homeostasis GO:0055080 212 0.457
Mouse
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.457
Mouse
t cell activation involved in immune response GO:0002286 43 0.443
Mouse
positive regulation of cytokine production GO:0001819 174 0.433
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.418
Mouse
negative regulation of immune system process GO:0002683 209 0.405
Rat
hormone metabolic process GO:0042445 86 0.397
Mouse
cation transport GO:0006812 399 0.393
Mouse
protein refolding GO:0042026 1 0.385
alpha beta t cell activation involved in immune response GO:0002287 31 0.372
Mouse
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway GO:0002488 2 0.368
Mouse
regulation of cytokine production GO:0001817 266 0.364
Mouse
transition metal ion homeostasis GO:0055076 54 0.360
Mouse
production of molecular mediator of immune response GO:0002440 103 0.328
Mouse
lymphocyte differentiation GO:0030098 242 0.277
response to type i interferon GO:0034340 12 0.244
antigen processing and presentation of endogenous peptide antigen via mhc class ib via er pathway tap dependent GO:0002489 2 0.241
Mouse
inorganic cation import into cell GO:0098659 4 0.227
Mouse
metal ion homeostasis GO:0055065 189 0.210
Mouse
iron ion transport GO:0006826 17 0.196
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.158
lysosomal transport GO:0007041 10 0.153
retina homeostasis GO:0001895 23 0.152
reactive oxygen species metabolic process GO:0072593 84 0.151
ear development GO:0043583 200 0.143
actin cytoskeleton organization GO:0030036 220 0.141
negative regulation of immune effector process GO:0002698 55 0.139
Rat
negative regulation of cell activation GO:0050866 111 0.133
guanosine containing compound metabolic process GO:1901068 144 0.133
myosin filament organization GO:0031033 3 0.117
negative regulation of leukocyte mediated immunity GO:0002704 29 0.115
Rat
cellular amino acid metabolic process GO:0006520 103 0.111
cell activation involved in immune response GO:0002263 126 0.111
Mouse
response to protozoan GO:0001562 28 0.111
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.111
cellular ketone metabolic process GO:0042180 84 0.110
leukocyte differentiation GO:0002521 342 0.108
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.106
cellular response to interferon gamma GO:0071346 25 0.103
interspecies interaction between organisms GO:0044419 83 0.102
negative regulation of innate immune response GO:0045824 17 0.101
Rat
nitric oxide biosynthetic process GO:0006809 25 0.101
Mouse
negative regulation of defense response to virus by host GO:0050689 1 0.094
myosin filament assembly GO:0031034 2 0.094
purine containing compound catabolic process GO:0072523 213 0.092
ribonucleoside triphosphate catabolic process GO:0009203 199 0.089
regulation of cell adhesion GO:0030155 154 0.087
epithelial cell proliferation GO:0050673 174 0.086
viral life cycle GO:0019058 36 0.083
purine ribonucleotide catabolic process GO:0009154 208 0.082
progesterone metabolic process GO:0042448 4 0.082
organic cyclic compound catabolic process GO:1901361 295 0.081
cellular response to cytokine stimulus GO:0071345 189 0.078
negative regulation of cell proliferation GO:0008285 296 0.078
response to inorganic substance GO:0010035 96 0.075
maintenance of location GO:0051235 89 0.069
nucleoside catabolic process GO:0009164 206 0.067
immunoglobulin mediated immune response GO:0016064 69 0.064
ribose phosphate metabolic process GO:0019693 291 0.064
response to organic cyclic compound GO:0014070 198 0.063
regulation of nitric oxide biosynthetic process GO:0045428 18 0.063
Mouse
regulation of mast cell differentiation GO:0060375 3 0.061
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.060
glycosyl compound metabolic process GO:1901657 246 0.060
cell adhesion GO:0007155 329 0.057
rna interference GO:0016246 2 0.056
methylation GO:0032259 134 0.055
protein folding GO:0006457 28 0.055
citrate metabolic process GO:0006101 3 0.055
purine nucleoside triphosphate catabolic process GO:0009146 203 0.055
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
protection from natural killer cell mediated cytotoxicity GO:0042270 2 0.054
apoptotic signaling pathway GO:0097190 306 0.052
peptidyl tyrosine modification GO:0018212 145 0.052
response to interleukin 2 GO:0070669 2 0.051
heterocycle catabolic process GO:0046700 280 0.051
negative regulation of leukocyte differentiation GO:1902106 51 0.050
positive regulation of protein complex assembly GO:0031334 45 0.050
b cell differentiation GO:0030183 78 0.049
interleukin 1 production GO:0032612 31 0.048
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.047
neuron apoptotic process GO:0051402 142 0.047
cellular amine metabolic process GO:0044106 44 0.046
positive regulation of tolerance induction GO:0002645 8 0.045
Rat
interleukin 4 mediated signaling pathway GO:0035771 2 0.044
keratinocyte proliferation GO:0043616 21 0.043
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 9 0.043
regulation of cytokine biosynthetic process GO:0042035 59 0.043
carbohydrate derivative catabolic process GO:1901136 231 0.042
muscle cell development GO:0055001 133 0.041
negative regulation of defense response GO:0031348 77 0.041
Rat
ras protein signal transduction GO:0007265 77 0.041
regulation of cytoplasmic transport GO:1903649 112 0.041
cytokine biosynthetic process GO:0042089 68 0.040
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.040
positive regulation of lymphocyte activation GO:0051251 140 0.039
gtp metabolic process GO:0046039 144 0.039
ribonucleotide metabolic process GO:0009259 291 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.038
nucleoside phosphate catabolic process GO:1901292 222 0.037
macromolecule catabolic process GO:0009057 281 0.037
nitrogen compound transport GO:0071705 271 0.037
negative regulation of t cell activation GO:0050868 65 0.037
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.037
Rat
regulation of lymphocyte activation GO:0051249 240 0.037
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.037
negative regulation of cell killing GO:0031342 8 0.036
Rat
protein polymerization GO:0051258 57 0.036
purine ribonucleoside metabolic process GO:0046128 241 0.036
steroid metabolic process GO:0008202 119 0.036
t helper 1 type immune response GO:0042088 25 0.036
female sex differentiation GO:0046660 84 0.035
regulation of t cell activation GO:0050863 170 0.035
positive regulation of interferon gamma production GO:0032729 39 0.035
Mouse
cellular response to biotic stimulus GO:0071216 92 0.034
striated muscle myosin thick filament assembly GO:0071688 1 0.034
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.034
Rat
type i interferon signaling pathway GO:0060337 10 0.034
regulation of hormone levels GO:0010817 211 0.033
Mouse
blood vessel morphogenesis GO:0048514 285 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.033
response to metal ion GO:0010038 47 0.033
endocytosis GO:0006897 168 0.033
eye photoreceptor cell differentiation GO:0001754 41 0.033
cell type specific apoptotic process GO:0097285 268 0.032
aromatic compound catabolic process GO:0019439 286 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
macrophage migration inhibitory factor signaling pathway GO:0035691 2 0.032
regulation of protein ubiquitination GO:0031396 52 0.032
positive regulation of mast cell differentiation GO:0060376 1 0.031
multicellular organism growth GO:0035264 161 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.031
regulation of viral transcription GO:0046782 3 0.031
purine nucleotide metabolic process GO:0006163 302 0.030
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.030
humoral immune response GO:0006959 57 0.030
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.029
response to interferon gamma GO:0034341 34 0.029
isoleucine metabolic process GO:0006549 4 0.029
macromolecule methylation GO:0043414 120 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
posttranscriptional regulation of gene expression GO:0010608 155 0.028
sequestering of calcium ion GO:0051208 18 0.027
peptidyl tyrosine phosphorylation GO:0018108 143 0.027
cellular protein complex assembly GO:0043623 116 0.027
posttranscriptional gene silencing by rna GO:0035194 10 0.027
response to organonitrogen compound GO:0010243 246 0.027
negative regulation of epithelial cell proliferation GO:0050680 64 0.027
response to lipopolysaccharide GO:0032496 128 0.027
posttranscriptional gene silencing GO:0016441 10 0.027
intracellular protein transport GO:0006886 204 0.026
rac protein signal transduction GO:0016601 13 0.026
positive regulation of rig i signaling pathway GO:1900246 1 0.026
intracellular transport of virus GO:0075733 1 0.026
sulfur compound metabolic process GO:0006790 100 0.026
photoreceptor cell differentiation GO:0046530 52 0.025
positive regulation of complement activation GO:0045917 2 0.025
regulation of cell motility GO:2000145 236 0.025
cytokine mediated signaling pathway GO:0019221 115 0.025
positive regulation of cell activation GO:0050867 158 0.025
cellular amide metabolic process GO:0043603 58 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
protein ubiquitination GO:0016567 171 0.024
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.024
organophosphate catabolic process GO:0046434 232 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.024
positive regulation of antigen processing and presentation GO:0002579 10 0.024
mast cell apoptotic process GO:0033024 5 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
striated muscle cell development GO:0055002 125 0.023
alpha beta t cell lineage commitment GO:0002363 7 0.023
positive regulation of b cell mediated immunity GO:0002714 26 0.023
positive regulation of response to cytokine stimulus GO:0060760 11 0.023
negative regulation of protein transport GO:0051224 46 0.023
cellular modified amino acid metabolic process GO:0006575 63 0.023
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.023
b cell mediated immunity GO:0019724 71 0.023
rho protein signal transduction GO:0007266 32 0.023
syncytium formation by plasma membrane fusion GO:0000768 42 0.023
protein import GO:0017038 101 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
microtubule cytoskeleton organization GO:0000226 157 0.023
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.023
ribonucleoside metabolic process GO:0009119 245 0.022
positive regulation of cell death GO:0010942 224 0.022
protein catabolic process GO:0030163 221 0.022
actomyosin structure organization GO:0031032 56 0.022
regulation of neuron apoptotic process GO:0043523 122 0.022
male gamete generation GO:0048232 285 0.022
peptidyl amino acid modification GO:0018193 336 0.022
response to drug GO:0042493 75 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
t helper 17 cell lineage commitment GO:0072540 4 0.021
positive regulation of lymphocyte differentiation GO:0045621 61 0.021
regulation of intracellular protein transport GO:0033157 82 0.021
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 2 0.021
t cell differentiation GO:0030217 174 0.021
negative regulation of cytoplasmic transport GO:1903650 29 0.021
covalent chromatin modification GO:0016569 163 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
regulation of cytoskeleton organization GO:0051493 122 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
somatic stem cell maintenance GO:0035019 47 0.020
regulation of epithelial cell proliferation GO:0050678 141 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
t helper 1 cell lineage commitment GO:0002296 2 0.020
cytoplasmic transport GO:0016482 234 0.020
t cell proliferation GO:0042098 120 0.020
protein alkylation GO:0008213 81 0.020
regulation of cell migration GO:0030334 219 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
epinephrine transport GO:0048241 1 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.019
gtp catabolic process GO:0006184 143 0.019
response to interferon beta GO:0035456 22 0.019
nucleoside metabolic process GO:0009116 246 0.019
protein localization to organelle GO:0033365 185 0.019
regulation of intracellular transport GO:0032386 159 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
somatic cell dna recombination GO:0016444 51 0.019
negative regulation of homeostatic process GO:0032845 71 0.019
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.019
response to peptide hormone GO:0043434 127 0.019
regulation of vasculature development GO:1901342 88 0.019
taurine metabolic process GO:0019530 4 0.019
regulation of t cell proliferation GO:0042129 92 0.019
developmental maturation GO:0021700 193 0.019
interferon gamma mediated signaling pathway GO:0060333 5 0.019
macrophage fusion GO:0034238 3 0.018
gland development GO:0048732 330 0.018
leukocyte proliferation GO:0070661 172 0.018
transport of virus GO:0046794 1 0.018
response to peptide GO:1901652 136 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.017
gene silencing by mirna GO:0035195 10 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
chromatin modification GO:0016568 187 0.017
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 5 0.017
Rat
regulation of actin nucleation GO:0051125 4 0.017
positive regulation of innate immune response GO:0045089 80 0.016
Mouse
extracellular matrix organization GO:0030198 147 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
nucleotide catabolic process GO:0009166 217 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
alpha beta t cell differentiation GO:0046632 69 0.016
segmentation GO:0035282 93 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
regulation of protein complex assembly GO:0043254 83 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
regulation of alpha beta t cell proliferation GO:0046640 18 0.016
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.016
spermatogenesis GO:0007283 284 0.016
negative regulation of viral transcription GO:0032897 3 0.016
positive regulation of actin nucleation GO:0051127 3 0.015
chromatin organization GO:0006325 206 0.015
rhythmic process GO:0048511 174 0.015
respiratory system development GO:0060541 190 0.015
glycoprotein metabolic process GO:0009100 116 0.015
ossification GO:0001503 216 0.015
negative regulation of t cell differentiation GO:0045581 23 0.015
natural killer cell proliferation GO:0001787 3 0.015
cellular lactam metabolic process GO:0072338 3 0.015
organelle assembly GO:0070925 177 0.015
lipid localization GO:0010876 126 0.015
stem cell development GO:0048864 219 0.015
amine metabolic process GO:0009308 45 0.015
development of primary female sexual characteristics GO:0046545 73 0.015
cellular response to peptide GO:1901653 92 0.015
response to growth factor GO:0070848 198 0.015
neuron death GO:0070997 154 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
dna metabolic process GO:0006259 303 0.015
purine nucleoside metabolic process GO:0042278 241 0.014
protein import into nucleus GO:0006606 95 0.014
regulation of neuron migration GO:2001222 22 0.014
alpha amino acid metabolic process GO:1901605 59 0.014
monosaccharide metabolic process GO:0005996 106 0.014
negative regulation of cell motility GO:2000146 61 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
actin filament polymerization GO:0030041 44 0.014
regulation of alpha beta t cell activation GO:0046634 53 0.014
cellular response to lipid GO:0071396 145 0.014
protein maturation GO:0051604 176 0.014
response to dsrna GO:0043331 30 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
neural tube development GO:0021915 160 0.014
b cell activation GO:0042113 161 0.014
negative regulation of cytokine production GO:0001818 84 0.014
nucleotide metabolic process GO:0009117 332 0.014
protein localization to nucleus GO:0034504 121 0.014
skeletal muscle organ development GO:0060538 163 0.013
protein targeting GO:0006605 143 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of myeloid leukocyte differentiation GO:0002761 58 0.013
regulation of natural killer cell activation GO:0032814 22 0.013
regulation of immunological synapse formation GO:2000520 2 0.013
carbohydrate catabolic process GO:0016052 32 0.013
renal system development GO:0072001 225 0.013
regulation of macrophage fusion GO:0034239 3 0.013
sequestering of metal ion GO:0051238 19 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
glucose homeostasis GO:0042593 128 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
valine metabolic process GO:0006573 4 0.013
t helper cell differentiation GO:0042093 28 0.013
germ cell development GO:0007281 185 0.013
endodermal cell fate specification GO:0001714 4 0.013
prostate gland development GO:0030850 48 0.013
mrna metabolic process GO:0016071 84 0.013
histone modification GO:0016570 159 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
extracellular structure organization GO:0043062 148 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
multicellular organismal catabolic process GO:0044243 7 0.013
protein activation cascade GO:0072376 19 0.012
myofibril assembly GO:0030239 34 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
positive thymic t cell selection GO:0045059 13 0.012
positive regulation of t cell differentiation GO:0045582 52 0.012
viral transcription GO:0019083 3 0.012
response to interleukin 15 GO:0070672 3 0.012
positive regulation of organelle organization GO:0010638 128 0.012
tissue homeostasis GO:0001894 115 0.012
creatine metabolic process GO:0006600 4 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
purine containing compound metabolic process GO:0072521 311 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
feeding behavior GO:0007631 62 0.012
t cell differentiation involved in immune response GO:0002292 30 0.012
regulation of proteolysis GO:0030162 164 0.012
negative regulation of macrophage fusion GO:0034240 1 0.012
regulation of actin filament based process GO:0032970 99 0.012
glycolytic process GO:0006096 20 0.012
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.012
muscle tissue development GO:0060537 308 0.012
positive regulation of activation of membrane attack complex GO:0001970 2 0.012
negative regulation of cell migration GO:0030336 59 0.012
regulation of interleukin 1 alpha production GO:0032650 4 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
pyrimidine containing compound catabolic process GO:0072529 3 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
negative regulation of interferon beta production GO:0032688 3 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.011
female gonad development GO:0008585 71 0.011
protein methylation GO:0006479 81 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
syncytium formation GO:0006949 43 0.011
regulation of protein kinase b signaling GO:0051896 56 0.011
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.011
sensory organ morphogenesis GO:0090596 242 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
inflammatory response GO:0006954 244 0.011
carbohydrate metabolic process GO:0005975 230 0.011
regulation of t cell differentiation GO:0045580 83 0.011
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.011
peptidyl lysine modification GO:0018205 77 0.011
carbohydrate homeostasis GO:0033500 128 0.011
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
synaptic transmission GO:0007268 329 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
natural killer cell differentiation GO:0001779 21 0.011
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.011
isotype switching to ige isotypes GO:0048289 7 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
atp metabolic process GO:0046034 75 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
cellular lipid metabolic process GO:0044255 323 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
regulation of angiogenesis GO:0045765 81 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
amide transport GO:0042886 138 0.010
neuromuscular process GO:0050905 99 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
response to amino acid GO:0043200 37 0.010
mucosal associated lymphoid tissue development GO:0048537 12 0.010
regulation of immunoglobulin production GO:0002637 42 0.010
interaction with host GO:0051701 22 0.010
central nervous system neuron differentiation GO:0021953 162 0.010
gliogenesis GO:0042063 141 0.010
regulation of cellular catabolic process GO:0031329 242 0.010

H2-K1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 0 0.414
severe combined immunodeficiency DOID:627 0 0.414
combined t cell and b cell immunodeficiency DOID:628 0 0.414
immune system disease DOID:2914 0 0.414
disease of anatomical entity DOID:7 0 0.414
nervous system disease DOID:863 0 0.021
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013