Mus musculus

35 known processes

Frat1

frequently rearranged in advanced T-cell lymphomas

(Aliases: AW060382)

Frat1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.055
cellular amine metabolic process GO:0044106 44 0.043
cell type specific apoptotic process GO:0097285 268 0.041
muscle tissue development GO:0060537 308 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.038
response to organonitrogen compound GO:0010243 246 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
amine metabolic process GO:0009308 45 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.031
regulation of organelle organization GO:0033043 289 0.031
regulation of membrane potential GO:0042391 192 0.029
cellular ketone metabolic process GO:0042180 84 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.028
cytoplasmic transport GO:0016482 234 0.028
heterocycle catabolic process GO:0046700 280 0.028
response to lipopolysaccharide GO:0032496 128 0.028
regulation of transferase activity GO:0051338 263 0.027
transmission of nerve impulse GO:0019226 76 0.027
cellular response to lipid GO:0071396 145 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
myeloid cell differentiation GO:0030099 233 0.026
response to inorganic substance GO:0010035 96 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
regulation of response to wounding GO:1903034 189 0.025
multicellular organismal signaling GO:0035637 91 0.025
regulation of lymphocyte activation GO:0051249 240 0.024
histone modification GO:0016570 159 0.024
negative regulation of molecular function GO:0044092 258 0.024
aromatic compound catabolic process GO:0019439 286 0.024
regulation of hormone levels GO:0010817 211 0.024
positive regulation of kinase activity GO:0033674 155 0.023
t cell activation GO:0042110 289 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
response to organic cyclic compound GO:0014070 198 0.023
positive regulation of cell death GO:0010942 224 0.022
positive regulation of protein modification process GO:0031401 299 0.022
leukocyte differentiation GO:0002521 342 0.022
peptidyl amino acid modification GO:0018193 336 0.022
maintenance of location GO:0051235 89 0.022
homeostasis of number of cells GO:0048872 210 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
chromatin organization GO:0006325 206 0.022
cellular chemical homeostasis GO:0055082 215 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
negative regulation of immune system process GO:0002683 209 0.022
apoptotic signaling pathway GO:0097190 306 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
muscle cell differentiation GO:0042692 261 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
gland development GO:0048732 330 0.021
nitrogen compound transport GO:0071705 271 0.021
positive regulation of programmed cell death GO:0043068 218 0.020
glucose homeostasis GO:0042593 128 0.020
regulation of kinase activity GO:0043549 249 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
cytokine production GO:0001816 319 0.020
striated muscle tissue development GO:0014706 293 0.020
peptide hormone secretion GO:0030072 109 0.020
regulation of hydrolase activity GO:0051336 246 0.020
cellular response to acid chemical GO:0071229 68 0.020
immune effector process GO:0002252 321 0.020
cellular response to hormone stimulus GO:0032870 150 0.019
regulation of cell activation GO:0050865 289 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
camera type eye development GO:0043010 266 0.019
organophosphate catabolic process GO:0046434 232 0.019
regulation of protein kinase activity GO:0045859 232 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
small molecule biosynthetic process GO:0044283 132 0.019
neuronal action potential GO:0019228 54 0.019
response to radiation GO:0009314 165 0.019
blood circulation GO:0008015 195 0.018
developmental maturation GO:0021700 193 0.018
carbohydrate homeostasis GO:0033500 128 0.018
protein processing GO:0016485 163 0.018
positive regulation of transferase activity GO:0051347 167 0.018
action potential GO:0001508 78 0.018
regulation of proteolysis GO:0030162 164 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.017
axonogenesis GO:0007409 274 0.017
anatomical structure homeostasis GO:0060249 145 0.017
amide transport GO:0042886 138 0.017
regulation of neuron death GO:1901214 134 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of intracellular transport GO:0032386 159 0.017
dna metabolic process GO:0006259 303 0.017
inflammatory response GO:0006954 244 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
transmembrane transport GO:0055085 412 0.017
protein maturation GO:0051604 176 0.017
actin cytoskeleton organization GO:0030036 220 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
hormone secretion GO:0046879 128 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
regulation of ion transport GO:0043269 215 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
heart morphogenesis GO:0003007 178 0.016
negative regulation of protein modification process GO:0031400 163 0.016
leukocyte mediated immunity GO:0002443 174 0.016
regulation of secretion GO:0051046 274 0.016
cellular lipid metabolic process GO:0044255 323 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
retina development in camera type eye GO:0060041 119 0.016
blood vessel morphogenesis GO:0048514 285 0.016
oxidation reduction process GO:0055114 342 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of cytokine production GO:0001817 266 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
ion transmembrane transport GO:0034220 361 0.016
rho protein signal transduction GO:0007266 32 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
regulation of mapk cascade GO:0043408 248 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
innate immune response GO:0045087 157 0.015
regulation of secretion by cell GO:1903530 249 0.015
lipid localization GO:0010876 126 0.015
adaptive immune response GO:0002250 155 0.015
regulation of cell projection organization GO:0031344 206 0.015
covalent chromatin modification GO:0016569 163 0.015
t cell differentiation GO:0030217 174 0.015
lymphocyte differentiation GO:0030098 242 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
regulation of inflammatory response GO:0050727 147 0.015
response to peptide GO:1901652 136 0.015
cognition GO:0050890 149 0.015
fatty acid metabolic process GO:0006631 121 0.014
angiogenesis GO:0001525 201 0.014
lipid biosynthetic process GO:0008610 179 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
ensheathment of neurons GO:0007272 76 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
positive regulation of cell development GO:0010720 237 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
carbohydrate metabolic process GO:0005975 230 0.014
regulation of protein localization GO:0032880 231 0.014
meiotic cell cycle GO:0051321 122 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
wound healing GO:0042060 157 0.014
ras protein signal transduction GO:0007265 77 0.014
positive regulation of cell activation GO:0050867 158 0.014
multi multicellular organism process GO:0044706 109 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
regulation of cell migration GO:0030334 219 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
cytokinetic process GO:0032506 2 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
wnt signaling pathway GO:0016055 188 0.014
anion transport GO:0006820 177 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
nucleotide metabolic process GO:0009117 332 0.014
organelle localization GO:0051640 179 0.013
calcium ion homeostasis GO:0055074 127 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
response to insulin GO:0032868 100 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
purine containing compound metabolic process GO:0072521 311 0.013
telencephalon development GO:0021537 186 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
circulatory system process GO:0003013 197 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
fat cell differentiation GO:0045444 160 0.013
protein localization to organelle GO:0033365 185 0.013
mapk cascade GO:0000165 281 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
membrane organization GO:0061024 245 0.013
macromolecule catabolic process GO:0009057 281 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
placenta development GO:0001890 140 0.013
regulation of neuron differentiation GO:0045664 281 0.013
purine containing compound catabolic process GO:0072523 213 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
positive regulation of cytokine production GO:0001819 174 0.013
development of primary sexual characteristics GO:0045137 143 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
dephosphorylation GO:0016311 129 0.012
regulation of body fluid levels GO:0050878 162 0.012
respiratory tube development GO:0030323 167 0.012
mitochondrion organization GO:0007005 134 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of cell cycle GO:0051726 281 0.012
cellular homeostasis GO:0019725 240 0.012
neuron death GO:0070997 154 0.012
tube formation GO:0035148 140 0.012
microtubule based process GO:0007017 236 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
response to oxygen levels GO:0070482 62 0.012
ossification GO:0001503 216 0.012
myeloid cell homeostasis GO:0002262 114 0.012
chemotaxis GO:0006935 247 0.012
regulation of t cell activation GO:0050863 170 0.012
divalent metal ion transport GO:0070838 172 0.012
epithelial cell proliferation GO:0050673 174 0.012
negative regulation of cell cycle GO:0045786 123 0.012
respiratory system development GO:0060541 190 0.011
mitotic cytokinesis GO:0000281 4 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
regulation of map kinase activity GO:0043405 120 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
negative regulation of ossification GO:0030279 49 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
negative regulation of nervous system development GO:0051961 156 0.011
positive regulation of immune effector process GO:0002699 107 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
chromatin modification GO:0016568 187 0.011
response to acid chemical GO:0001101 111 0.011
sensory perception GO:0007600 245 0.011
sequestering of calcium ion GO:0051208 18 0.011
cellular response to external stimulus GO:0071496 88 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
regulation of cell cycle process GO:0010564 160 0.011
regulation of reproductive process GO:2000241 66 0.011
nuclear division GO:0000280 158 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
peptide secretion GO:0002790 114 0.011
cell adhesion GO:0007155 329 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
long chain fatty acid import GO:0044539 2 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
leukocyte apoptotic process GO:0071887 71 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
tissue homeostasis GO:0001894 115 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
cellular ion homeostasis GO:0006873 165 0.011
organelle fission GO:0048285 170 0.011
gonad development GO:0008406 141 0.011
sensory organ morphogenesis GO:0090596 242 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
positive regulation of secretion GO:0051047 130 0.011
meiotic nuclear division GO:0007126 115 0.011
positive regulation of cell migration GO:0030335 109 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
leukocyte proliferation GO:0070661 172 0.011
cation transport GO:0006812 399 0.011
regulation of system process GO:0044057 200 0.011
regulation of binding GO:0051098 111 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
endomembrane system organization GO:0010256 147 0.011
response to oxidative stress GO:0006979 123 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
sulfur compound metabolic process GO:0006790 100 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
cation homeostasis GO:0055080 212 0.010
cofactor metabolic process GO:0051186 80 0.010
response to light stimulus GO:0009416 135 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
multi organism behavior GO:0051705 62 0.010
male gamete generation GO:0048232 285 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
nucleoside metabolic process GO:0009116 246 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
divalent inorganic cation transport GO:0072511 178 0.010
erythrocyte differentiation GO:0030218 88 0.010
extracellular matrix organization GO:0030198 147 0.010
nuclear transport GO:0051169 139 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
regulation of peptide hormone secretion GO:0090276 75 0.010
extracellular structure organization GO:0043062 148 0.010
spermatogenesis GO:0007283 284 0.010

Frat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
central nervous system disease DOID:331 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
neurodegenerative disease DOID:1289 0 0.011
immune system disease DOID:2914 0 0.010
hematopoietic system disease DOID:74 0 0.010