Mus musculus

80 known processes

Prrx2

paired related homeobox 2

(Aliases: S8,Prx2)

Prrx2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
Mouse
negative regulation of prostatic bud formation GO:0060686 4 1.000
appendage morphogenesis GO:0035107 149 1.000
auditory receptor cell fate determination GO:0042668 3 0.999
skeletal system development GO:0001501 356 0.999
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.999
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.998
regulation of chondrocyte differentiation GO:0032330 33 0.997
embryonic organ morphogenesis GO:0048562 276 0.997
embryonic skeletal system development GO:0048706 120 0.997
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.997
skeletal system morphogenesis GO:0048705 203 0.997
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.995
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.995
chondrocyte differentiation GO:0002062 72 0.994
epithelial tube morphogenesis GO:0060562 303 0.994
embryonic heart tube formation GO:0003144 1 0.993
tendon formation GO:0035992 4 0.993
regionalization GO:0003002 337 0.993
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.993
regulation of cartilage development GO:0061035 44 0.993
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.993
trachea cartilage morphogenesis GO:0060535 4 0.992
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.991
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.991
limb morphogenesis GO:0035108 149 0.990
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.990
morphogenesis of embryonic epithelium GO:0016331 159 0.990
cartilage morphogenesis GO:0060536 11 0.990
neural tube closure GO:0001843 90 0.990
limb development GO:0060173 166 0.987
pyramidal neuron migration GO:0021852 1 0.987
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.986
cartilage development GO:0051216 140 0.985
mesenchyme development GO:0060485 152 0.982
Mouse
noradrenergic neuron differentiation GO:0003357 6 0.982
Mouse
bone development GO:0060348 120 0.980
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.979
hindbrain tangential cell migration GO:0021934 2 0.979
Mouse
midbrain hindbrain boundary maturation GO:0021732 1 0.978
embryonic skeletal system morphogenesis GO:0048704 91 0.978
mesenchymal cell differentiation GO:0048762 107 0.976
Mouse
chondrocyte development GO:0002063 24 0.975
embryonic appendage morphogenesis GO:0035113 126 0.974
astrocyte fate commitment GO:0060018 4 0.973
blood vessel morphogenesis GO:0048514 285 0.971
endochondral bone morphogenesis GO:0060350 50 0.969
ossification GO:0001503 216 0.967
somitogenesis GO:0001756 69 0.967
embryonic nail plate morphogenesis GO:0035880 3 0.966
mammary gland morphogenesis GO:0060443 54 0.966
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.963
mesenchymal cell development GO:0014031 93 0.962
Mouse
ureteric bud development GO:0001657 94 0.960
negative regulation of gastrulation GO:2000542 3 0.958
ear development GO:0043583 200 0.955
paraxial mesodermal cell fate commitment GO:0048343 2 0.954
embryonic limb morphogenesis GO:0030326 126 0.954
regulation of cellular ketone metabolic process GO:0010565 66 0.951
trachea formation GO:0060440 3 0.951
mesenchymal cell proliferation GO:0010463 44 0.949
stem cell development GO:0048864 219 0.946
Mouse
mesonephros development GO:0001823 97 0.946
tendon cell differentiation GO:0035990 4 0.944
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.943
metanephric capsule specification GO:0072267 1 0.942
branching morphogenesis of an epithelial tube GO:0048754 159 0.941
hypophysis morphogenesis GO:0048850 3 0.940
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.937
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.934
axon guidance GO:0007411 141 0.931
Mouse
lung development GO:0030324 164 0.929
bone trabecula formation GO:0060346 9 0.928
axis elongation involved in somitogenesis GO:0090245 4 0.927
negative regulation of cell development GO:0010721 169 0.925
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.923
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.923
palate development GO:0060021 76 0.922
Mouse
noradrenergic neuron development GO:0003358 3 0.921
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.921
negative regulation of chondrocyte differentiation GO:0032331 13 0.917
negative regulation of endodermal cell differentiation GO:1903225 1 0.915
stem cell differentiation GO:0048863 268 0.914
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.912
regulation of endodermal cell fate specification GO:0042663 2 0.910
appendage development GO:0048736 166 0.909
embryonic digit morphogenesis GO:0042733 56 0.902
neural tube formation GO:0001841 108 0.901
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.899
regulation of ossification GO:0030278 112 0.897
hemangioblast cell differentiation GO:0060217 1 0.897
cell proliferation in hindbrain GO:0021534 10 0.895
spinal cord development GO:0021510 81 0.893
Mouse
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.891
regulation of fat cell differentiation GO:0045598 81 0.889
positive regulation of stem cell proliferation GO:2000648 59 0.887
hindbrain development GO:0030902 128 0.887
Mouse
telencephalon development GO:0021537 186 0.885
embryonic heart tube development GO:0035050 65 0.885
regulation of skeletal muscle fiber development GO:0048742 36 0.884
diencephalon development GO:0021536 63 0.884
bmp signaling pathway GO:0030509 93 0.877
cerebellum formation GO:0021588 1 0.876
respiratory system development GO:0060541 190 0.876
Mouse
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.869
regulation of bmp signaling pathway GO:0030510 60 0.867
gastrulation GO:0007369 116 0.867
response to bmp GO:0071772 14 0.867
Mouse
regulation of endodermal cell differentiation GO:1903224 2 0.862
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.860
morphogenesis of a branching epithelium GO:0061138 193 0.860
regulation of neuron projection development GO:0010975 169 0.858
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.857
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.855
mesonephric tubule development GO:0072164 94 0.852
formation of primary germ layer GO:0001704 77 0.852
mesonephric tubule morphogenesis GO:0072171 63 0.851
growth plate cartilage development GO:0003417 14 0.848
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.848
regulation of apoptotic signaling pathway GO:2001233 197 0.848
cartilage condensation GO:0001502 18 0.845
negative regulation of cartilage development GO:0061037 17 0.844
odontogenesis GO:0042476 78 0.842
pituitary gland development GO:0021983 38 0.840
central nervous system neuron differentiation GO:0021953 162 0.840
Mouse
hindbrain formation GO:0021576 1 0.840
cranial suture morphogenesis GO:0060363 8 0.837
positive regulation of osteoblast differentiation GO:0045669 34 0.836
cardiac epithelial to mesenchymal transition GO:0060317 18 0.834
pallium development GO:0021543 120 0.833
bmp signaling pathway involved in heart development GO:0061312 2 0.832
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.830
cell fate specification GO:0001708 72 0.829
positive regulation of cartilage development GO:0061036 18 0.828
regulation of wnt signaling pathway GO:0030111 123 0.826
tube formation GO:0035148 140 0.821
negative regulation of epithelial cell proliferation GO:0050680 64 0.819
otic placode formation GO:0043049 1 0.818
negative regulation of neuron differentiation GO:0045665 101 0.816
Mouse
nephron tubule morphogenesis GO:0072078 68 0.816
endochondral bone growth GO:0003416 19 0.815
biomineral tissue development GO:0031214 64 0.815
embryonic skeletal joint morphogenesis GO:0060272 11 0.814
regulation of myoblast differentiation GO:0045661 29 0.811
regulation of auditory receptor cell differentiation GO:0045607 4 0.808
positive regulation of ureteric bud formation GO:0072107 3 0.807
paraxial mesodermal cell differentiation GO:0048342 2 0.806
striated muscle cell development GO:0055002 125 0.802
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.800
positive regulation of ossification GO:0045778 47 0.799
midbrain development GO:0030901 35 0.799
Mouse
bone morphogenesis GO:0060349 78 0.799
renal system development GO:0072001 225 0.798
osteoblast development GO:0002076 17 0.797
nephric duct formation GO:0072179 4 0.796
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.794
epidermis development GO:0008544 187 0.792
positive regulation of bone mineralization GO:0030501 12 0.791
olfactory bulb interneuron development GO:0021891 7 0.790
regulation of epithelial to mesenchymal transition GO:0010717 22 0.790
embryonic heart tube morphogenesis GO:0003143 51 0.788
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.788
ameboidal type cell migration GO:0001667 128 0.787
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.785
forebrain generation of neurons GO:0021872 63 0.784
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.784
primary neural tube formation GO:0014020 95 0.784
embryonic epithelial tube formation GO:0001838 130 0.784
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.782
pancreatic pp cell fate commitment GO:0003329 2 0.782
primitive streak formation GO:0090009 10 0.782
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.781
axial mesodermal cell fate commitment GO:0048322 1 0.779
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.779
lung induction GO:0060492 3 0.779
cerebellar granule cell precursor proliferation GO:0021930 10 0.777
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.777
angiogenesis GO:0001525 201 0.777
endocrine system development GO:0035270 98 0.775
neural crest formation GO:0014029 2 0.774
negative regulation of bmp signaling pathway GO:0030514 35 0.774
cardiac chamber morphogenesis GO:0003206 93 0.773
neural crest cell fate commitment GO:0014034 1 0.772
negative regulation of heart looping GO:1901208 1 0.771
epithelial to mesenchymal transition GO:0001837 47 0.762
regulation of astrocyte differentiation GO:0048710 20 0.762
renal vesicle induction GO:0072034 3 0.761
cellular response to growth factor stimulus GO:0071363 197 0.760
Mouse
trophectodermal cellular morphogenesis GO:0001831 3 0.759
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.758
forebrain development GO:0030900 302 0.753
smoothened signaling pathway GO:0007224 105 0.749
small molecule biosynthetic process GO:0044283 132 0.749
neural tube patterning GO:0021532 43 0.747
regulation of heart morphogenesis GO:2000826 22 0.747
salivary gland morphogenesis GO:0007435 33 0.744
muscle cell development GO:0055001 133 0.744
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.738
endodermal cell fate commitment GO:0001711 12 0.736
inner ear morphogenesis GO:0042472 101 0.731
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.725
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.724
muscle fiber development GO:0048747 76 0.724
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.720
regulation of bone mineralization GO:0030500 31 0.718
forelimb morphogenesis GO:0035136 40 0.717
skeletal muscle cell differentiation GO:0035914 66 0.716
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.715
closure of optic fissure GO:0061386 2 0.713
skeletal muscle organ development GO:0060538 163 0.712
Mouse
positive regulation of nervous system development GO:0051962 221 0.710
Mouse
negative regulation of branching involved in ureteric bud morphogenesis GO:0090191 4 0.707
prostate gland morphogenesis GO:0060512 32 0.707
neuron projection guidance GO:0097485 141 0.704
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.703
embryonic camera type eye development GO:0031076 36 0.700
fat cell differentiation GO:0045444 160 0.699
dorsal ventral neural tube patterning GO:0021904 28 0.699
stem cell proliferation GO:0072089 117 0.698
negative regulation of alcohol biosynthetic process GO:1902931 4 0.697
ear morphogenesis GO:0042471 118 0.696
neuroepithelial cell differentiation GO:0060563 37 0.696
embryonic eye morphogenesis GO:0048048 29 0.691
corticotropin hormone secreting cell differentiation GO:0060128 3 0.691
negative regulation of cell fate specification GO:0009996 4 0.689
diencephalon morphogenesis GO:0048852 6 0.686
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.676
central nervous system vasculogenesis GO:0022009 3 0.675
apoptotic process involved in morphogenesis GO:0060561 25 0.675
replacement ossification GO:0036075 26 0.674
positive regulation of apoptotic process GO:0043065 217 0.672
negative regulation of endodermal cell fate specification GO:0042664 1 0.665
negative regulation of stem cell maintenance GO:1902455 4 0.664
placenta blood vessel development GO:0060674 31 0.661
endodermal cell fate specification GO:0001714 4 0.659
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.658
forebrain radial glial cell differentiation GO:0021861 4 0.658
neural crest cell differentiation GO:0014033 54 0.657
Mouse
digestive tract morphogenesis GO:0048546 147 0.655
forebrain anterior posterior pattern specification GO:0021797 5 0.652
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.651
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.646
metanephric capsule formation GO:0072266 1 0.639
hindlimb morphogenesis GO:0035137 42 0.638
regulation of muscle tissue development GO:1901861 97 0.636
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.634
mitotic cell cycle process GO:1903047 159 0.633
cell division GO:0051301 120 0.633
cell proliferation in forebrain GO:0021846 30 0.632
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.631
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.626
amine metabolic process GO:0009308 45 0.624
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.623
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.623
regulation of cell migration GO:0030334 219 0.622
mesonephric duct morphogenesis GO:0072180 4 0.622
muscle cell differentiation GO:0042692 261 0.620
response to growth factor GO:0070848 198 0.620
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.620
respiratory tube development GO:0030323 167 0.614
urogenital system development GO:0001655 261 0.614
cardiac septum development GO:0003279 59 0.614
globus pallidus development GO:0021759 2 0.613
connective tissue development GO:0061448 179 0.612
negative regulation of neuron projection development GO:0010977 50 0.611
cardiac atrium development GO:0003230 24 0.607
gland development GO:0048732 330 0.607
trachea development GO:0060438 18 0.603
mesenchymal to epithelial transition GO:0060231 12 0.603
renal capsule formation GO:0072129 1 0.602
skin morphogenesis GO:0043589 38 0.601
regulation of mitotic cell cycle GO:0007346 126 0.601
outflow tract morphogenesis GO:0003151 53 0.600
inner ear receptor cell differentiation GO:0060113 61 0.600
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.600
regulation of cell cycle process GO:0010564 160 0.598
epithelial cell fate commitment GO:0072148 13 0.597
mammary placode formation GO:0060596 4 0.596
mesodermal cell fate commitment GO:0001710 17 0.596
metanephric renal vesicle morphogenesis GO:0072283 12 0.595
regulation of kidney development GO:0090183 40 0.594
endothelial cell differentiation GO:0045446 41 0.593
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.593
cardiac atrium morphogenesis GO:0003209 23 0.592
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.592
actin cytoskeleton organization GO:0030036 220 0.590
morphogenesis of a branching structure GO:0001763 203 0.589
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.587
prostate gland epithelium morphogenesis GO:0060740 31 0.586
fungiform papilla development GO:0061196 6 0.586
endocardial cushion formation GO:0003272 13 0.585
heart field specification GO:0003128 6 0.584
positive regulation of transcription by glucose GO:0046016 3 0.583
glial cell migration GO:0008347 7 0.581
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.581
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.581
axonogenesis GO:0007409 274 0.579
Mouse
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.578
regulation of odontogenesis GO:0042481 18 0.577
regulation of cell adhesion GO:0030155 154 0.577
regulation of ketone biosynthetic process GO:0010566 2 0.576
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.576
positive regulation of cell development GO:0010720 237 0.575
Mouse
apoptotic signaling pathway GO:0097190 306 0.574
dopaminergic neuron differentiation GO:0071542 14 0.573
Mouse
metanephric nephron tubule formation GO:0072289 4 0.571
embryonic viscerocranium morphogenesis GO:0048703 8 0.571
positive regulation of cell migration GO:0030335 109 0.570
wound healing spreading of epidermal cells GO:0035313 5 0.566
anterior commissure morphogenesis GO:0021960 6 0.563
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.562
heart morphogenesis GO:0003007 178 0.561
craniofacial suture morphogenesis GO:0097094 10 0.560
metanephric mesenchyme development GO:0072075 10 0.559
branch elongation involved in ureteric bud branching GO:0060681 3 0.558
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.556
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.554
sensory organ morphogenesis GO:0090596 242 0.554
spinal cord association neuron differentiation GO:0021527 14 0.553
neural crest cell migration GO:0001755 32 0.552
Mouse
embryonic skeletal joint development GO:0072498 13 0.549
cardiac right atrium morphogenesis GO:0003213 3 0.547
mesenchymal cell differentiation involved in renal system development GO:2001012 6 0.546
regulation of stem cell differentiation GO:2000736 50 0.546
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.544
odontogenesis of dentin containing tooth GO:0042475 66 0.542
cardiac septum morphogenesis GO:0060411 46 0.542
cerebellar granular layer development GO:0021681 13 0.541
regulation of prostatic bud formation GO:0060685 6 0.541
mesonephric epithelium development GO:0072163 94 0.540
skeletal muscle satellite cell differentiation GO:0014816 6 0.538
cell proliferation in external granule layer GO:0021924 10 0.538
central nervous system neuron development GO:0021954 67 0.537
Mouse
endocardial cushion development GO:0003197 26 0.536
regulation of lens epithelial cell proliferation GO:2001109 1 0.535
formation of radial glial scaffolds GO:0021943 4 0.530
apoptotic process involved in development GO:1902742 28 0.530
positive regulation of cell death GO:0010942 224 0.529
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.526
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.525
regulation of mast cell differentiation GO:0060375 3 0.520
cellular amine metabolic process GO:0044106 44 0.520
cell type specific apoptotic process GO:0097285 268 0.516
embryonic placenta development GO:0001892 98 0.515
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.515
nephron tubule formation GO:0072079 20 0.514
negative regulation of epidermis development GO:0045683 9 0.514
positive regulation of kidney development GO:0090184 28 0.512
regulation of retina development in camera type eye GO:1902866 3 0.512
regulation of myotube differentiation GO:0010830 62 0.511
regulation of cell motility GO:2000145 236 0.511
carbon catabolite repression of transcription GO:0045013 1 0.509
skeletal muscle fiber development GO:0048741 58 0.509
peptidyl amino acid modification GO:0018193 336 0.507
ventricular zone neuroblast division GO:0021847 3 0.505
chondroblast differentiation GO:0060591 2 0.501
vascular wound healing GO:0061042 3 0.497
neural crest cell development GO:0014032 48 0.497
Mouse
cellular response to hormone stimulus GO:0032870 150 0.496
regulation of embryonic development GO:0045995 71 0.495
catagen GO:0042637 5 0.495
heart valve morphogenesis GO:0003179 21 0.494
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.491
positive regulation of protein modification process GO:0031401 299 0.490
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.489
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.488
mitral valve development GO:0003174 4 0.487
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.485
cellular ketone metabolic process GO:0042180 84 0.481
forebrain neuron differentiation GO:0021879 52 0.480
hair follicle development GO:0001942 85 0.479
regulation of response to wounding GO:1903034 189 0.474
regulation of smoothened signaling pathway GO:0008589 58 0.473
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.469
forebrain cell migration GO:0021885 58 0.469
organ induction GO:0001759 21 0.468
hindbrain morphogenesis GO:0021575 46 0.467
regulation of ureteric bud formation GO:0072106 3 0.466
chemotaxis GO:0006935 247 0.465
Mouse
negative regulation of axon extension GO:0030517 19 0.465
negative regulation of cell proliferation GO:0008285 296 0.463
Mouse
positive regulation of cell proliferation involved in heart morphogenesis GO:2000138 5 0.462
forebrain morphogenesis GO:0048853 17 0.461
regulation of neuron differentiation GO:0045664 281 0.459
Mouse
cell adhesion GO:0007155 329 0.455
kidney mesenchyme development GO:0072074 14 0.454
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.453
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.453
olfactory lobe development GO:0021988 32 0.450
regulation of vascular wound healing GO:0061043 2 0.450
cardiac right ventricle formation GO:0003219 3 0.449
cerebellum development GO:0021549 77 0.449
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.448
positive regulation of epithelial cell proliferation GO:0050679 68 0.446
regulation of nuclear division GO:0051783 56 0.445
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.444
extrinsic apoptotic signaling pathway GO:0097191 126 0.442
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.441
embryonic forelimb morphogenesis GO:0035115 32 0.438
positive regulation of programmed cell death GO:0043068 218 0.434
otic vesicle development GO:0071599 14 0.434
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.431
digestive tract development GO:0048565 190 0.431
glomerulus morphogenesis GO:0072102 10 0.431
ventricular septum morphogenesis GO:0060412 27 0.430
bone mineralization GO:0030282 54 0.429
positive regulation of neuron differentiation GO:0045666 141 0.429
Mouse
embryonic genitalia morphogenesis GO:0030538 4 0.429
cardiac muscle tissue development GO:0048738 130 0.421
pericardium development GO:0060039 16 0.418
negative regulation of astrocyte differentiation GO:0048712 10 0.418
mitral valve morphogenesis GO:0003183 4 0.415
specification of organ identity GO:0010092 30 0.412
cardiac chamber development GO:0003205 108 0.411
kidney epithelium development GO:0072073 121 0.410
growth plate cartilage chondrocyte growth GO:0003430 2 0.410
negative regulation of myoblast differentiation GO:0045662 18 0.410
positive regulation of anagen GO:0051885 1 0.408
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.406
skin development GO:0043588 220 0.402
cell cell signaling involved in cell fate commitment GO:0045168 35 0.399
positive regulation of cellular amine metabolic process GO:0033240 5 0.399
optic vesicle morphogenesis GO:0003404 2 0.398
nail development GO:0035878 5 0.396
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.395
trochlear nerve development GO:0021558 3 0.391
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.391
frontal suture morphogenesis GO:0060364 2 0.388
male genitalia morphogenesis GO:0048808 4 0.388
mesoderm formation GO:0001707 62 0.387
muscle tissue morphogenesis GO:0060415 53 0.386
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.385
cell differentiation in spinal cord GO:0021515 53 0.385
Mouse
dorsal spinal cord development GO:0021516 20 0.384
Mouse
neuron fate determination GO:0048664 9 0.384
mesoderm development GO:0007498 100 0.382
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.380
floor plate morphogenesis GO:0033505 3 0.378
developmental growth involved in morphogenesis GO:0060560 138 0.377
forebrain neuroblast division GO:0021873 9 0.377
neural tube development GO:0021915 160 0.374
endoderm formation GO:0001706 20 0.374
metencephalon development GO:0022037 89 0.373
Mouse
mesonephric tubule formation GO:0072172 11 0.372
positive regulation of cell motility GO:2000147 116 0.370
regulation of skeletal muscle cell differentiation GO:2001014 11 0.369
lipid biosynthetic process GO:0008610 179 0.369
midbrain hindbrain boundary development GO:0030917 9 0.369
spinal cord motor neuron cell fate specification GO:0021520 13 0.367
endocardial cushion morphogenesis GO:0003203 18 0.367
cell proliferation involved in kidney development GO:0072111 14 0.367
positive regulation of meiosis GO:0045836 14 0.366
epithelial tube formation GO:0072175 130 0.360
regulation of neural retina development GO:0061074 3 0.360
activation of meiosis GO:0090427 4 0.360
gonad development GO:0008406 141 0.360
growth plate cartilage chondrocyte development GO:0003431 3 0.359
renal tubule development GO:0061326 87 0.358
wnt signaling pathway GO:0016055 188 0.357
cell proliferation in midbrain GO:0033278 2 0.356
positive regulation of cell adhesion GO:0045785 80 0.354
exocrine system development GO:0035272 45 0.354
epithelial cell development GO:0002064 159 0.353
positive regulation of wnt signaling pathway GO:0030177 45 0.352
oxidation reduction process GO:0055114 342 0.351
endocardial cushion to mesenchymal transition GO:0090500 5 0.351
cerebellar cortex development GO:0021695 48 0.351
myotube differentiation GO:0014902 105 0.351
regulation of organ formation GO:0003156 34 0.351
regulation of cellular amino acid metabolic process GO:0006521 5 0.350
neuron projection extension GO:1990138 64 0.350
immature t cell proliferation in thymus GO:0033080 7 0.350
regulation of cell projection organization GO:0031344 206 0.347
cardiogenic plate morphogenesis GO:0003142 1 0.345
glomerular mesangial cell development GO:0072144 3 0.342
molting cycle GO:0042303 90 0.340
positive regulation of bmp signaling pathway GO:0030513 23 0.339
retinal bipolar neuron differentiation GO:0060040 5 0.337
negative regulation of kidney development GO:0090185 15 0.337
myeloid leukocyte differentiation GO:0002573 119 0.337
stem cell maintenance GO:0019827 130 0.337
auditory receptor cell fate specification GO:0042667 1 0.336
thalamus development GO:0021794 11 0.335
mesenchymal cell proliferation involved in ureteric bud development GO:0072138 3 0.335
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.334
steroid metabolic process GO:0008202 119 0.332
tube closure GO:0060606 91 0.331
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.331
oocyte axis specification GO:0007309 2 0.331
small gtpase mediated signal transduction GO:0007264 97 0.331
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.330
cellular response to bmp stimulus GO:0071773 14 0.330
Mouse
male gonad development GO:0008584 88 0.327
male sex differentiation GO:0046661 109 0.327

Prrx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.929
musculoskeletal system disease DOID:17 0 0.929
connective tissue disease DOID:65 0 0.891
bone development disease DOID:0080006 0 0.846
bone disease DOID:0080001 0 0.846