Mus musculus

48 known processes

Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

(Aliases: AA409156,1110067B02Rik,mKIAA1479,Sema6D-2,Sema6D-1,Sema6D-6,Sema6D-5,Sema6D-4,D330011G23)

Sema6d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron projection extension GO:1990138 64 0.884
Mouse
t cell activation GO:0042110 289 0.744
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.715
transmembrane transport GO:0055085 412 0.626
inflammatory response GO:0006954 244 0.599
regulation of ras gtpase activity GO:0032318 88 0.594
Mouse
sympathetic neuron projection guidance GO:0097491 4 0.569
Mouse
cellular metal ion homeostasis GO:0006875 151 0.561
branchiomotor neuron axon guidance GO:0021785 7 0.549
Mouse
stem cell differentiation GO:0048863 268 0.544
Mouse
nucleotide catabolic process GO:0009166 217 0.519
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.517
ion transmembrane transport GO:0034220 361 0.501
blood circulation GO:0008015 195 0.501
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.500
g protein coupled receptor signaling pathway GO:0007186 243 0.494
ras protein signal transduction GO:0007265 77 0.466
regulation of nucleotide metabolic process GO:0006140 169 0.464
Mouse
axonogenesis GO:0007409 274 0.447
Mouse Fly
leukocyte migration GO:0050900 124 0.437
regulation of cell migration GO:0030334 219 0.436
myeloid cell differentiation GO:0030099 233 0.435
trunk neural crest cell migration GO:0036484 4 0.410
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.404
cation transport GO:0006812 399 0.400
regulation of system process GO:0044057 200 0.397
Mouse
cation homeostasis GO:0055080 212 0.392
cerebellar granule cell precursor tangential migration GO:0021935 1 0.387
trigeminal nerve morphogenesis GO:0021636 6 0.382
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.382
Mouse
glycoprotein metabolic process GO:0009100 116 0.378
heart contraction GO:0060047 93 0.374
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.366
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.357
Mouse
neuron projection guidance GO:0097485 141 0.355
Mouse Fly
regulation of blood circulation GO:1903522 93 0.352
Mouse
sympathetic neuron projection extension GO:0097490 4 0.351
Mouse
cell adhesion GO:0007155 329 0.350
negative regulation of phosphate metabolic process GO:0045936 184 0.348
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.344
negative regulation of protein metabolic process GO:0051248 282 0.339
Mouse
developmental cell growth GO:0048588 84 0.330
Mouse
purine containing compound metabolic process GO:0072521 311 0.327
Mouse
negative regulation of cellular component organization GO:0051129 194 0.324
Mouse
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.321
apoptotic signaling pathway GO:0097190 306 0.318
smooth muscle cell migration GO:0014909 10 0.312
gliogenesis GO:0042063 141 0.310
positive regulation of cell development GO:0010720 237 0.306
Mouse
purine nucleotide metabolic process GO:0006163 302 0.299
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.298
gtp catabolic process GO:0006184 143 0.298
Mouse
regulation of cell cycle GO:0051726 281 0.294
ribose phosphate metabolic process GO:0019693 291 0.293
Mouse
microglia development GO:0014005 2 0.292
positive regulation of cell migration GO:0030335 109 0.291
regulation of membrane potential GO:0042391 192 0.290
lymphocyte activation involved in immune response GO:0002285 93 0.289
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.286
Mouse
negative regulation of cell growth GO:0030308 44 0.283
Mouse
positive regulation of cell motility GO:2000147 116 0.283
mapk cascade GO:0000165 281 0.277
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.277
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.276
Mouse
t cell differentiation GO:0030217 174 0.275
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.269
Mouse
homeostasis of number of cells GO:0048872 210 0.268
nucleoside phosphate metabolic process GO:0006753 338 0.267
Mouse
fat cell differentiation GO:0045444 160 0.266
cell growth GO:0016049 130 0.262
Mouse
regulation of axon guidance GO:1902667 13 0.260
Mouse Fly
negative regulation of ras protein signal transduction GO:0046580 18 0.259
regulation of ion transport GO:0043269 215 0.259
action potential GO:0001508 78 0.255
lymphocyte differentiation GO:0030098 242 0.255
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.253
Mouse
angiogenesis GO:0001525 201 0.250
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.249
leukocyte differentiation GO:0002521 342 0.248
Mouse
negative regulation of axon guidance GO:1902668 8 0.248
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.246
Mouse
heterocycle catabolic process GO:0046700 280 0.245
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.242
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.236
Mouse
epithelial tube morphogenesis GO:0060562 303 0.236
Mouse
transmission of nerve impulse GO:0019226 76 0.230
ribonucleoside metabolic process GO:0009119 245 0.229
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.227
extrinsic apoptotic signaling pathway GO:0097191 126 0.225
purine ribonucleotide catabolic process GO:0009154 208 0.225
Mouse
regulation of cell activation GO:0050865 289 0.225
regulation of cell motility GO:2000145 236 0.224
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.222
Mouse
granulocyte migration GO:0097530 43 0.222
neuron migration GO:0001764 122 0.217
Mouse
cellular homeostasis GO:0019725 240 0.217
cellular calcium ion homeostasis GO:0006874 119 0.215
guanosine containing compound catabolic process GO:1901069 144 0.214
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.213
organonitrogen compound catabolic process GO:1901565 264 0.212
Mouse
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.211
positive regulation of gtp catabolic process GO:0033126 85 0.211
Mouse
peptidyl amino acid modification GO:0018193 336 0.210
Mouse
regulation of map kinase activity GO:0043405 120 0.210
positive regulation of nucleoside metabolic process GO:0045979 91 0.207
Mouse
positive regulation of behavior GO:0048520 40 0.207
purine nucleoside catabolic process GO:0006152 205 0.202
Mouse
regulation of lymphocyte activation GO:0051249 240 0.202
glycoprotein biosynthetic process GO:0009101 89 0.199
regulation of erk1 and erk2 cascade GO:0070372 71 0.198
cellular response to cytokine stimulus GO:0071345 189 0.198
positive regulation of ras gtpase activity GO:0032320 65 0.198
Mouse
positive regulation of nervous system development GO:0051962 221 0.197
Mouse
actin cytoskeleton organization GO:0030036 220 0.196
nucleoside catabolic process GO:0009164 206 0.194
Mouse
immune effector process GO:0002252 321 0.194
Mouse
rho protein signal transduction GO:0007266 32 0.194
regulation of cell size GO:0008361 72 0.194
Mouse Fly
positive regulation of nucleotide metabolic process GO:0045981 114 0.192
Mouse
cellular ketone metabolic process GO:0042180 84 0.191
positive regulation of lymphocyte activation GO:0051251 140 0.188
rhythmic process GO:0048511 174 0.188
regulation of inflammatory response GO:0050727 147 0.186
purine containing compound catabolic process GO:0072523 213 0.186
Mouse
positive regulation of t cell activation GO:0050870 101 0.185
cytokine production GO:0001816 319 0.184
leukocyte homeostasis GO:0001776 79 0.184
cerebral cortex cell migration GO:0021795 44 0.183
Mouse
regulation of neuron differentiation GO:0045664 281 0.181
Mouse Fly
inorganic ion transmembrane transport GO:0098660 234 0.181
positive regulation of cellular catabolic process GO:0031331 148 0.180
Mouse
blood vessel morphogenesis GO:0048514 285 0.179
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.179
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.178
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.177
Mouse
gtp metabolic process GO:0046039 144 0.175
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.174
purine ribonucleoside metabolic process GO:0046128 241 0.173
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.169
blood coagulation GO:0007596 76 0.166
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.165
positive regulation of mapk cascade GO:0043410 170 0.165
epithelial cell migration GO:0010631 63 0.164
Mouse
neutrophil chemotaxis GO:0030593 36 0.164
positive regulation of cell activation GO:0050867 158 0.164
regulation of ras protein signal transduction GO:0046578 114 0.163
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.162
organophosphate catabolic process GO:0046434 232 0.161
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.161
Mouse
positive regulation of map kinase activity GO:0043406 84 0.159
negative regulation of phosphorus metabolic process GO:0010563 184 0.157
Mouse
metal ion homeostasis GO:0055065 189 0.156
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.156
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.154
t cell migration GO:0072678 19 0.154
purine nucleoside triphosphate metabolic process GO:0009144 226 0.154
Mouse
telencephalon development GO:0021537 186 0.153
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.153
regulation of cellular component size GO:0032535 121 0.152
Mouse Fly
positive regulation of chemotaxis GO:0050921 38 0.152
regulation of extent of cell growth GO:0061387 52 0.152
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.151
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.150
t cell activation involved in immune response GO:0002286 43 0.150
Mouse
morphogenesis of a branching structure GO:0001763 203 0.149
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.148
regulation of mapk cascade GO:0043408 248 0.148
ameboidal type cell migration GO:0001667 128 0.147
Mouse
myeloid leukocyte migration GO:0097529 57 0.147
anion transport GO:0006820 177 0.147
positive regulation of protein modification process GO:0031401 299 0.147
Mouse
neuronal action potential GO:0019228 54 0.145
axon guidance GO:0007411 141 0.145
Mouse Fly
regulation of muscle system process GO:0090257 80 0.145
positive regulation of ion transport GO:0043270 65 0.144
learning or memory GO:0007611 148 0.144
immune response activating signal transduction GO:0002757 116 0.144
glial cell differentiation GO:0010001 131 0.143
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.143
Mouse Fly
anatomical structure homeostasis GO:0060249 145 0.142
cell activation involved in immune response GO:0002263 126 0.142
Mouse
locomotory behavior GO:0007626 195 0.141
Fly
regulation of chemotaxis GO:0050920 53 0.141
Mouse Fly
cellular extravasation GO:0045123 17 0.140
protein kinase b signaling GO:0043491 74 0.137
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.136
Mouse
alpha beta t cell activation GO:0046631 91 0.136
Mouse
response to organonitrogen compound GO:0010243 246 0.136
purine nucleoside metabolic process GO:0042278 241 0.136
Mouse
regulation of body fluid levels GO:0050878 162 0.136
nucleotide metabolic process GO:0009117 332 0.135
Mouse
purine nucleotide catabolic process GO:0006195 211 0.135
Mouse
monocyte extravasation GO:0035696 2 0.134
glycosyl compound catabolic process GO:1901658 206 0.134
Mouse
sequestering of calcium ion GO:0051208 18 0.133
regulation of angiogenesis GO:0045765 81 0.133
Mouse
granulocyte chemotaxis GO:0071621 39 0.132
positive regulation of leukocyte proliferation GO:0070665 73 0.132
ventral trunk neural crest cell migration GO:0036486 4 0.132
Mouse
negative regulation of phosphorylation GO:0042326 166 0.131
Mouse
erk1 and erk2 cascade GO:0070371 77 0.131
positive regulation of cellular amine metabolic process GO:0033240 5 0.131
divalent metal ion transport GO:0070838 172 0.130
cell chemotaxis GO:0060326 81 0.129
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.129
axon extension involved in axon guidance GO:0048846 14 0.128
Mouse
regulation of gtp catabolic process GO:0033124 113 0.128
Mouse
regulation of response to wounding GO:1903034 189 0.128
regulation of protein serine threonine kinase activity GO:0071900 157 0.127
peptidyl tyrosine modification GO:0018212 145 0.127
Mouse
wnt signaling pathway GO:0016055 188 0.127
pallium development GO:0021543 120 0.125
Mouse
divalent inorganic cation transport GO:0072511 178 0.124
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.124
regulation of muscle contraction GO:0006937 49 0.124
regulation of anatomical structure size GO:0090066 178 0.123
Mouse Fly
leukocyte chemotaxis GO:0030595 69 0.123
regulation of vasculature development GO:1901342 88 0.122
Mouse
multicellular organismal homeostasis GO:0048871 164 0.122
negative regulation of growth GO:0045926 99 0.120
Mouse
brown fat cell differentiation GO:0050873 36 0.120
cd4 positive alpha beta t cell activation GO:0035710 45 0.119
Mouse
regulation of metal ion transport GO:0010959 106 0.119
positive regulation of kinase activity GO:0033674 155 0.119
immune response regulating signaling pathway GO:0002764 125 0.118
myeloid cell homeostasis GO:0002262 114 0.118
facial nerve structural organization GO:0021612 10 0.117
Mouse
regulation of ion homeostasis GO:2000021 64 0.117
gland development GO:0048732 330 0.117
Mouse
regulation of transmembrane transport GO:0034762 128 0.117
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.117
Mouse
microglia differentiation GO:0014004 2 0.117
regulation of cytokine production GO:0001817 266 0.117
embryonic placenta development GO:0001892 98 0.115
antigen receptor mediated signaling pathway GO:0050851 64 0.115
cellular divalent inorganic cation homeostasis GO:0072503 127 0.115
regulation of purine nucleotide metabolic process GO:1900542 169 0.115
Mouse
telencephalon cell migration GO:0022029 55 0.114
Mouse
regulation of homeostatic process GO:0032844 182 0.113
calcium ion homeostasis GO:0055074 127 0.113
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.113
relaxation of vascular smooth muscle GO:0060087 7 0.113
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.111
membrane organization GO:0061024 245 0.111
glial cell development GO:0021782 54 0.110
regulation of axon extension GO:0030516 43 0.110
Mouse
regulation of osteoblast proliferation GO:0033688 15 0.110
amino acid transport GO:0006865 61 0.109
extracellular structure organization GO:0043062 148 0.109
exocrine system development GO:0035272 45 0.109
Mouse
synaptic transmission GO:0007268 329 0.109
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.109
Mouse
facioacoustic ganglion development GO:1903375 3 0.108
Mouse
cell matrix adhesion GO:0007160 68 0.107
regulation of t cell differentiation GO:0045580 83 0.105
divalent inorganic cation homeostasis GO:0072507 138 0.105
negative regulation of neuron death GO:1901215 98 0.104
regulation of phospholipase c activity GO:1900274 3 0.104
cell division GO:0051301 120 0.104
regulation of t cell activation GO:0050863 170 0.103
maintenance of location GO:0051235 89 0.103
defense response to other organism GO:0098542 197 0.102
tissue homeostasis GO:0001894 115 0.102
organonitrogen compound biosynthetic process GO:1901566 192 0.102
memory GO:0007613 58 0.102
regulation of smooth muscle cell migration GO:0014910 6 0.101
regulation of organelle organization GO:0033043 289 0.100
motor neuron axon guidance GO:0008045 26 0.100
Mouse Fly
regulation of monocyte extravasation GO:2000437 2 0.099
positive regulation of gtpase activity GO:0043547 85 0.098
Mouse
purine nucleotide biosynthetic process GO:0006164 65 0.098
cellular amine metabolic process GO:0044106 44 0.098
negative regulation of synaptic vesicle transport GO:1902804 3 0.096
fibroblast proliferation GO:0048144 35 0.096
nucleobase containing small molecule metabolic process GO:0055086 352 0.096
Mouse
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.096
positive regulation of organelle organization GO:0010638 128 0.095
positive regulation of smooth muscle cell migration GO:0014911 4 0.094
response to light stimulus GO:0009416 135 0.093
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.093
muscle contraction GO:0006936 101 0.093
blood vessel remodeling GO:0001974 33 0.093
cellular response to growth factor stimulus GO:0071363 197 0.093
regulation of protein kinase activity GO:0045859 232 0.093
neutrophil migration GO:1990266 37 0.093
morphogenesis of a branching epithelium GO:0061138 193 0.092
Mouse
chemotaxis GO:0006935 247 0.092
Mouse Fly
organic acid transport GO:0015849 101 0.092
regulation of nucleoside metabolic process GO:0009118 130 0.092
Mouse
cellular amino acid metabolic process GO:0006520 103 0.091
response to lipopolysaccharide GO:0032496 128 0.090
positive regulation of homeostatic process GO:0032846 64 0.090
sensory perception GO:0007600 245 0.089
sphingolipid metabolic process GO:0006665 45 0.089
osteoclast differentiation GO:0030316 62 0.089
response to peptide hormone GO:0043434 127 0.089
neuron apoptotic process GO:0051402 142 0.089
regulation of leukocyte differentiation GO:1902105 159 0.088
cation transmembrane transport GO:0098655 266 0.087
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.087
amine metabolic process GO:0009308 45 0.086
digestive tract development GO:0048565 190 0.086
regulation of stress activated mapk cascade GO:0032872 69 0.086
activation of mapk activity GO:0000187 59 0.085
forebrain cell migration GO:0021885 58 0.085
Mouse
sodium ion transport GO:0006814 73 0.084
regulation of heart contraction GO:0008016 77 0.084
Mouse
glycerolipid metabolic process GO:0046486 122 0.084
glycerophospholipid metabolic process GO:0006650 71 0.083
photoreceptor cell development GO:0042461 40 0.083
macrophage differentiation GO:0030225 20 0.082
muscle cell differentiation GO:0042692 261 0.082
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.082
neural tube formation GO:0001841 108 0.082
Mouse
regulation of cell projection organization GO:0031344 206 0.082
Mouse Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.081
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.081
cell migration involved in vasculogenesis GO:0035441 2 0.081
positive regulation of phospholipase c activity GO:0010863 2 0.081
hemostasis GO:0007599 78 0.081
heart process GO:0003015 94 0.080
Mouse
second messenger mediated signaling GO:0019932 73 0.080
positive regulation of leukocyte differentiation GO:1902107 86 0.080
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.080
platelet activation GO:0030168 40 0.080
negative regulation of neuron apoptotic process GO:0043524 92 0.079
actin filament organization GO:0007015 113 0.079
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.078
cellular response to organonitrogen compound GO:0071417 145 0.078
salivary gland development GO:0007431 37 0.078
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.078
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.077
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.077
wound healing GO:0042060 157 0.076
adaptive immune response GO:0002250 155 0.076
Mouse
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.076
ribonucleotide catabolic process GO:0009261 208 0.075
Mouse
smooth muscle cell chemotaxis GO:0071670 2 0.075
anatomical structure arrangement GO:0048532 20 0.075
Mouse
regulation of protein kinase b signaling GO:0051896 56 0.074
positive regulation of calcium ion transport GO:0051928 27 0.074
positive regulation of endothelial cell proliferation GO:0001938 17 0.073
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.073
reactive oxygen species metabolic process GO:0072593 84 0.073
regulation of fibroblast proliferation GO:0048145 34 0.072
eye photoreceptor cell development GO:0042462 31 0.072
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.072
substrate dependent cell migration GO:0006929 18 0.072
Mouse
neuromuscular process GO:0050905 99 0.072
Fly
b cell activation GO:0042113 161 0.071
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.071
signal transduction in absence of ligand GO:0038034 55 0.071
cellular ion homeostasis GO:0006873 165 0.071
plasma membrane organization GO:0007009 90 0.070
nucleoside triphosphate catabolic process GO:0009143 205 0.070
Mouse
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.070
positive regulation of protein kinase b signaling GO:0051897 32 0.070
regulation of rho gtpase activity GO:0032319 58 0.069
Mouse
positive regulation of sodium ion transport GO:0010765 13 0.069
positive regulation of ion transmembrane transport GO:0034767 24 0.069
myofibril assembly GO:0030239 34 0.069
germ cell development GO:0007281 185 0.069
acute inflammatory response GO:0002526 41 0.069
lymphocyte proliferation GO:0046651 164 0.069
inorganic cation transmembrane transport GO:0098662 207 0.069
mesenchymal cell differentiation GO:0048762 107 0.068
Mouse
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.067
Mouse
nitrogen compound transport GO:0071705 271 0.067
establishment of neuroblast polarity GO:0045200 1 0.067
negative regulation of immune system process GO:0002683 209 0.067
intracellular protein transport GO:0006886 204 0.067
retina development in camera type eye GO:0060041 119 0.067
regulation of neuron death GO:1901214 134 0.067
central nervous system neuron differentiation GO:0021953 162 0.066
Mouse
regulation of cardiac muscle contraction GO:0055117 21 0.066
t cell receptor signaling pathway GO:0050852 46 0.066
cellular response to peptide GO:1901653 92 0.065
positive regulation of fibroblast proliferation GO:0048146 20 0.065
protein autophosphorylation GO:0046777 61 0.065
response to organic cyclic compound GO:0014070 198 0.065
limbic system development GO:0021761 72 0.065
Mouse
stem cell proliferation GO:0072089 117 0.065
mucopolysaccharide metabolic process GO:1903510 25 0.064
defense response to virus GO:0051607 68 0.064
positive regulation of epithelial cell proliferation GO:0050679 68 0.064
myelination GO:0042552 74 0.064
regulation of adaptive immune response GO:0002819 90 0.063
cytoplasmic transport GO:0016482 234 0.063
positive regulation of nucleotide catabolic process GO:0030813 88 0.063
Mouse
lymphocyte migration GO:0072676 26 0.063
visual learning GO:0008542 44 0.062
heart morphogenesis GO:0003007 178 0.062
cognition GO:0050890 149 0.062
metanephric mesenchymal cell migration GO:0035789 2 0.062
negative regulation of apoptotic signaling pathway GO:2001234 104 0.062
development of primary sexual characteristics GO:0045137 143 0.062
Mouse Worm
chemorepulsion of branchiomotor axon GO:0021793 1 0.061
amino acid transmembrane transport GO:0003333 37 0.061
negative regulation of protein modification process GO:0031400 163 0.061
Mouse
carboxylic acid transport GO:0046942 100 0.061
ribonucleoside triphosphate catabolic process GO:0009203 199 0.061
Mouse
cytokine production involved in immune response GO:0002367 34 0.060
regulation of cell adhesion GO:0030155 154 0.060
hindbrain development GO:0030902 128 0.060
Mouse
glycosyl compound metabolic process GO:1901657 246 0.059
Mouse
response to defenses of other organism involved in symbiotic interaction GO:0052173 3 0.059
carbohydrate derivative catabolic process GO:1901136 231 0.059
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.059
smooth muscle tissue development GO:0048745 22 0.059
t cell differentiation in thymus GO:0033077 77 0.058
positive regulation of immunological synapse formation GO:2000522 1 0.058
positive regulation of protein kinase activity GO:0045860 144 0.058
regulation of vasculogenesis GO:2001212 9 0.058
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.057
embryonic epithelial tube formation GO:0001838 130 0.057
Mouse
epidermis development GO:0008544 187 0.057
negative regulation of cytoskeleton organization GO:0051494 36 0.057
cytosolic calcium ion transport GO:0060401 48 0.057
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.057
cell fate commitment GO:0045165 210 0.056
ensheathment of neurons GO:0007272 76 0.056
development of primary female sexual characteristics GO:0046545 73 0.056
organic anion transport GO:0015711 137 0.056
ribonucleoside catabolic process GO:0042454 206 0.056
Mouse
muscle cell migration GO:0014812 19 0.056
microtubule based process GO:0007017 236 0.056
mating behavior sex discrimination GO:0048047 1 0.056
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.056
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.055
Mouse
hindbrain tangential cell migration GO:0021934 2 0.055
cardiac muscle contraction GO:0060048 32 0.055
tissue remodeling GO:0048771 102 0.055
coagulation GO:0050817 78 0.055
alpha beta t cell activation involved in immune response GO:0002287 31 0.055
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.055
carbohydrate metabolic process GO:0005975 230 0.055
regulation of kinase activity GO:0043549 249 0.055
positive regulation of transmembrane transport GO:0034764 29 0.054
nuclear division GO:0000280 158 0.054
digestive system development GO:0055123 200 0.054
aromatic compound catabolic process GO:0019439 286 0.054
Mouse
photoreceptor cell differentiation GO:0046530 52 0.054
anatomical structure maturation GO:0071695 49 0.054
Mouse
negative regulation of cell proliferation GO:0008285 296 0.054
regulation of transferase activity GO:0051338 263 0.053
ribonucleotide biosynthetic process GO:0009260 59 0.053
regulation of neuron migration GO:2001222 22 0.053
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.053
Mouse
cerebral cortex development GO:0021987 86 0.053
Mouse
cell substrate adhesion GO:0031589 130 0.053
regulation of ion transmembrane transporter activity GO:0032412 54 0.053
regulation of defense response GO:0031347 233 0.053
stem cell development GO:0048864 219 0.052
Mouse
protein modification by small protein conjugation GO:0032446 187 0.052
positive regulation of hydrolase activity GO:0051345 148 0.052
Mouse
labyrinthine layer development GO:0060711 49 0.052
regulation of voltage gated calcium channel activity GO:1901385 4 0.052
cellular chemical homeostasis GO:0055082 215 0.052
oligodendrocyte differentiation GO:0048709 53 0.052
innate immune response GO:0045087 157 0.052
associative learning GO:0008306 61 0.051
multicellular organismal signaling GO:0035637 91 0.051
t helper 2 cell differentiation GO:0045064 12 0.051
protein catabolic process GO:0030163 221 0.051
morphogenesis of embryonic epithelium GO:0016331 159 0.051
Mouse
erythrocyte differentiation GO:0030218 88 0.051
generation of precursor metabolites and energy GO:0006091 103 0.051
regulation of alpha beta t cell differentiation GO:0046637 35 0.050
phospholipid metabolic process GO:0006644 87 0.050
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.050
Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.050
skin development GO:0043588 220 0.050
actomyosin structure organization GO:0031032 56 0.050
response to insulin GO:0032868 100 0.049
multicellular organismal response to stress GO:0033555 62 0.049
regulation of lymphocyte differentiation GO:0045619 107 0.049
endothelial cell differentiation GO:0045446 41 0.049
response to growth factor GO:0070848 198 0.049
positive regulation of necrotic cell death GO:0010940 1 0.048
salivary gland morphogenesis GO:0007435 33 0.048
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.048
behavioral response to nutrient GO:0051780 1 0.048
pigmentation GO:0043473 71 0.048
negative regulation of neuron differentiation GO:0045665 101 0.048
Mouse
lipid transport GO:0006869 98 0.047
peptidyl serine phosphorylation GO:0018105 74 0.047
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.047
sympathetic nervous system development GO:0048485 22 0.047
Mouse
organelle localization GO:0051640 179 0.047
Mouse
canonical wnt signaling pathway GO:0060070 130 0.047
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.047
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.047
Mouse
membrane lipid metabolic process GO:0006643 53 0.046
t helper cell differentiation GO:0042093 28 0.046
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.046
Mouse
sequestering of metal ion GO:0051238 19 0.046

Sema6d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.078
disease of cellular proliferation DOID:14566 0 0.078