Mus musculus

86 known processes

Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

(Aliases: Sema6A-1,A730020P05Rik,Semaq,9330158E07,VIa,AI851735)

Sema6a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of ras gtpase activity GO:0032318 88 1.000
Mouse
negative regulation of axon guidance GO:1902668 8 1.000
Mouse
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.999
Mouse
trigeminal nerve morphogenesis GO:0021636 6 0.998
Mouse
facial nerve morphogenesis GO:0021610 11 0.998
Mouse
regulation of rho gtpase activity GO:0032319 58 0.997
Mouse
rho protein signal transduction GO:0007266 32 0.996
negative chemotaxis GO:0050919 14 0.996
Mouse
angiogenesis GO:0001525 201 0.995
Mouse
branching involved in salivary gland morphogenesis GO:0060445 26 0.994
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.994
Mouse Fly
neural tube closure GO:0001843 90 0.994
Mouse
neuron projection guidance GO:0097485 141 0.993
motor neuron axon guidance GO:0008045 26 0.993
Mouse Fly
gtp catabolic process GO:0006184 143 0.993
Mouse
negative regulation of neuron projection development GO:0010977 50 0.992
Mouse
trigeminal nerve development GO:0021559 10 0.991
Mouse
regulation of cell projection organization GO:0031344 206 0.991
Mouse Fly
cerebellar granule cell precursor tangential migration GO:0021935 1 0.991
facial nerve structural organization GO:0021612 10 0.990
Mouse
central nervous system projection neuron axonogenesis GO:0021952 21 0.990
embryonic epithelial tube formation GO:0001838 130 0.989
Mouse
regionalization GO:0003002 337 0.988
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.988
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.987
Mouse
regulation of neuron differentiation GO:0045664 281 0.986
Mouse Fly
heart morphogenesis GO:0003007 178 0.983
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.981
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.981
Mouse
neural tube development GO:0021915 160 0.980
Mouse
negative regulation of chemotaxis GO:0050922 11 0.978
Mouse
negative regulation of cell projection organization GO:0031345 56 0.977
Mouse
axonogenesis GO:0007409 274 0.977
cell migration in hindbrain GO:0021535 16 0.977
Mouse
regulation of neuron projection development GO:0010975 169 0.976
Mouse Fly
central nervous system neuron differentiation GO:0021953 162 0.976
Mouse
positive regulation of gtpase activity GO:0043547 85 0.973
Mouse
positive regulation of cell development GO:0010720 237 0.973
primary neural tube formation GO:0014020 95 0.971
Mouse
stem cell development GO:0048864 219 0.970
Mouse
ameboidal type cell migration GO:0001667 128 0.969
Mouse
regulation of gtp catabolic process GO:0033124 113 0.969
Mouse
neuron projection extension GO:1990138 64 0.968
Mouse
gland development GO:0048732 330 0.968
Mouse
regulation of axon extension GO:0030516 43 0.966
Mouse
regulation of cell migration GO:0030334 219 0.965
neuron recognition GO:0008038 25 0.965
Mouse Fly
negative regulation of neuron differentiation GO:0045665 101 0.963
Mouse
forebrain neuron development GO:0021884 30 0.963
Mouse
regulation of axon guidance GO:1902667 13 0.962
Mouse Fly
ossification involved in bone maturation GO:0043931 12 0.961
Mouse
ras protein signal transduction GO:0007265 77 0.960
axon extension involved in axon guidance GO:0048846 14 0.959
Mouse
cranial nerve development GO:0021545 41 0.957
Mouse
positive regulation of cell projection organization GO:0031346 95 0.956
Mouse
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.956
Mouse
gtp metabolic process GO:0046039 144 0.956
Mouse
neural tube formation GO:0001841 108 0.953
Mouse
axon guidance GO:0007411 141 0.951
regulation of rho protein signal transduction GO:0035023 71 0.951
Mouse
limbic system development GO:0021761 72 0.950
Mouse
postganglionic parasympathetic nervous system development GO:0021784 2 0.949
segmentation GO:0035282 93 0.948
Mouse
epithelial tube morphogenesis GO:0060562 303 0.945
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.945
positive regulation of nucleotide catabolic process GO:0030813 88 0.944
Mouse
telencephalon development GO:0021537 186 0.944
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.943
Mouse
ribonucleotide catabolic process GO:0009261 208 0.942
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.942
Mouse
central nervous system neuron axonogenesis GO:0021955 28 0.939
positive regulation of cellular catabolic process GO:0031331 148 0.939
Mouse
central nervous system neuron development GO:0021954 67 0.938
Mouse
cell adhesion GO:0007155 329 0.937
purine containing compound catabolic process GO:0072523 213 0.935
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.934
Mouse
glossopharyngeal nerve morphogenesis GO:0021615 4 0.932
regulation of nucleotide metabolic process GO:0006140 169 0.932
Mouse
regulation of smooth muscle cell migration GO:0014910 6 0.932
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.931
Mouse
synapse assembly GO:0007416 56 0.929
Fly
purine nucleotide catabolic process GO:0006195 211 0.926
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.926
Mouse
regulation of cell motility GO:2000145 236 0.924
epithelium migration GO:0090132 63 0.919
Mouse
aromatic compound catabolic process GO:0019439 286 0.918
Mouse
pallium development GO:0021543 120 0.915
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.911
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.910
Mouse
glycosyl compound catabolic process GO:1901658 206 0.909
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.907
Mouse
regulation of anatomical structure size GO:0090066 178 0.904
Mouse Fly
organonitrogen compound catabolic process GO:1901565 264 0.903
Mouse
purine nucleoside catabolic process GO:0006152 205 0.899
Mouse
forebrain development GO:0030900 302 0.898
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.891
Mouse
regulation of neuron migration GO:2001222 22 0.890
tissue migration GO:0090130 68 0.886
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.885
Mouse
hindbrain development GO:0030902 128 0.882
Mouse
nucleotide catabolic process GO:0009166 217 0.880
Mouse
anterior commissure morphogenesis GO:0021960 6 0.879
stem cell differentiation GO:0048863 268 0.875
Mouse
blood vessel morphogenesis GO:0048514 285 0.875
Mouse
negative regulation of growth GO:0045926 99 0.873
Mouse
negative regulation of cellular component organization GO:0051129 194 0.864
Mouse
salivary gland morphogenesis GO:0007435 33 0.864
Mouse
ribonucleoside catabolic process GO:0042454 206 0.859
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.857
Mouse
organophosphate catabolic process GO:0046434 232 0.854
Mouse
positive regulation of nervous system development GO:0051962 221 0.854
appendage development GO:0048736 166 0.852
cranial nerve structural organization GO:0021604 13 0.851
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.850
Mouse
bone development GO:0060348 120 0.845
Mouse
chemorepulsion of branchiomotor axon GO:0021793 1 0.844
ribose phosphate metabolic process GO:0019693 291 0.843
Mouse
sympathetic nervous system development GO:0048485 22 0.843
Mouse
anatomical structure maturation GO:0071695 49 0.842
Mouse
negative regulation of nervous system development GO:0051961 156 0.842
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.840
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.837
Mouse
chemotaxis GO:0006935 247 0.834
limb development GO:0060173 166 0.832
branching morphogenesis of an epithelial tube GO:0048754 159 0.826
regulation of cellular component size GO:0032535 121 0.823
Mouse Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.821
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.818
Mouse
tube closure GO:0060606 91 0.817
Mouse
negative regulation of behavior GO:0048521 14 0.812
Mouse
hippocampus development GO:0021766 52 0.811
endothelial cell migration GO:0043542 44 0.810
Mouse
negative regulation of cell growth GO:0030308 44 0.810
Mouse
skeletal system development GO:0001501 356 0.806
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.804
Mouse
heterocycle catabolic process GO:0046700 280 0.803
Mouse
regulation of cellular catabolic process GO:0031329 242 0.803
Mouse
bone maturation GO:0070977 13 0.797
Mouse
semaphorin plexin signaling pathway GO:0071526 21 0.797
stem cell proliferation GO:0072089 117 0.796
sympathetic neuron projection extension GO:0097490 4 0.796
Mouse
ossification GO:0001503 216 0.786
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.786
Mouse
cranial nerve morphogenesis GO:0021602 26 0.778
Mouse
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.777
Mouse
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.776
Mouse
somitogenesis GO:0001756 69 0.773
purine nucleoside triphosphate catabolic process GO:0009146 203 0.772
Mouse
nerve development GO:0021675 67 0.771
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.768
Mouse
neural precursor cell proliferation GO:0061351 121 0.766
facial nerve development GO:0021561 11 0.758
Mouse
axonal fasciculation GO:0007413 15 0.755
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.752
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.747
Mouse
trunk neural crest cell migration GO:0036484 4 0.745
Mouse
hindbrain tangential cell migration GO:0021934 2 0.745
synapse organization GO:0050808 125 0.745
Fly
exocrine system development GO:0035272 45 0.742
Mouse
ribonucleoside metabolic process GO:0009119 245 0.741
Mouse
purine nucleotide metabolic process GO:0006163 302 0.738
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.731
Mouse
tube formation GO:0035148 140 0.730
Mouse
organ maturation GO:0048799 17 0.729
Mouse
dendrite development GO:0016358 115 0.728
Mouse Fly
nucleobase containing small molecule metabolic process GO:0055086 352 0.727
Mouse
purine containing compound metabolic process GO:0072521 311 0.722
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.722
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.717
salivary gland development GO:0007431 37 0.715
Mouse
single organismal cell cell adhesion GO:0016337 131 0.703
neuroblast proliferation GO:0007405 49 0.702
guanosine containing compound catabolic process GO:1901069 144 0.699
Mouse
developmental maturation GO:0021700 193 0.699
Mouse
regulation of vasculature development GO:1901342 88 0.693
Mouse
nucleoside metabolic process GO:0009116 246 0.692
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.692
Mouse
positive regulation of jun kinase activity GO:0043507 30 0.687
positive regulation of transferase activity GO:0051347 167 0.681
embryonic organ morphogenesis GO:0048562 276 0.677
regulation of purine nucleotide metabolic process GO:1900542 169 0.676
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.675
Mouse
morphogenesis of a branching structure GO:0001763 203 0.674
Mouse
positive regulation of organelle organization GO:0010638 128 0.673
glycosyl compound metabolic process GO:1901657 246 0.669
Mouse
cellular amino acid metabolic process GO:0006520 103 0.661
epithelial cell migration GO:0010631 63 0.659
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.656
regulation of cell size GO:0008361 72 0.650
Mouse Fly
regulation of cytoskeleton organization GO:0051493 122 0.640
retinal ganglion cell axon guidance GO:0031290 18 0.639
leukocyte differentiation GO:0002521 342 0.635
Mouse
preganglionic parasympathetic nervous system development GO:0021783 17 0.627
Mouse
negative regulation of synapse assembly GO:0051964 3 0.620
amine metabolic process GO:0009308 45 0.618
positive regulation of cell migration GO:0030335 109 0.616
vagus nerve development GO:0021564 3 0.616
regulation of binding GO:0051098 111 0.614
bone trabecula morphogenesis GO:0061430 12 0.614
Mouse
purine nucleoside metabolic process GO:0042278 241 0.606
Mouse
gliogenesis GO:0042063 141 0.601
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.595
positive regulation of cytoskeleton organization GO:0051495 49 0.594
nucleotide metabolic process GO:0009117 332 0.586
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.572
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.571
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.569
cell recognition GO:0008037 83 0.569
Mouse Fly
glial cell differentiation GO:0010001 131 0.564
centrosome localization GO:0051642 13 0.559
cellular amine metabolic process GO:0044106 44 0.558
peripheral nervous system development GO:0007422 53 0.556
organelle localization GO:0051640 179 0.550
regulation of secretion GO:0051046 274 0.549
regulation of cellular amine metabolic process GO:0033238 20 0.544
regulation of hydrolase activity GO:0051336 246 0.543
Mouse
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.540
Mouse
regulation of chemotaxis GO:0050920 53 0.538
Mouse Fly
forebrain generation of neurons GO:0021872 63 0.537
Mouse
regulation of organelle organization GO:0033043 289 0.536
regulation of cellular response to stress GO:0080135 159 0.536
mesenchymal cell differentiation GO:0048762 107 0.528
Mouse
negative regulation of axon extension GO:0030517 19 0.524
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.523
Mouse
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.512
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.511
mapk cascade GO:0000165 281 0.507
sensory organ morphogenesis GO:0090596 242 0.506
negative regulation of phosphorus metabolic process GO:0010563 184 0.506
Mouse
parasympathetic nervous system development GO:0048486 19 0.505
Mouse
neural crest cell migration involved in sympathetic nervous system development GO:1903045 1 0.504
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.503
Mouse
negative regulation of cell proliferation GO:0008285 296 0.502
regulation of protein binding GO:0043393 60 0.496
neuron apoptotic process GO:0051402 142 0.495
positive regulation of protein phosphorylation GO:0001934 242 0.488
Mouse
regulation of epithelial cell migration GO:0010632 35 0.485
Mouse
locomotory behavior GO:0007626 195 0.479
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.467
Mouse
limb morphogenesis GO:0035108 149 0.462
substrate dependent cell migration GO:0006929 18 0.462
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.459
Mouse
regulation of protein kinase activity GO:0045859 232 0.457
positive regulation of neuron projection development GO:0010976 79 0.455
Mouse
single organism cell adhesion GO:0098602 156 0.454
limb bud formation GO:0060174 10 0.449
appendage morphogenesis GO:0035107 149 0.448
regulation of stress activated mapk cascade GO:0032872 69 0.444
blood circulation GO:0008015 195 0.443
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.442
regulation of neuron death GO:1901214 134 0.441
regulation of cell shape GO:0008360 39 0.439
Mouse
regulation of cell adhesion GO:0030155 154 0.438
neuron death GO:0070997 154 0.433
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.432
regulation of kinase activity GO:0043549 249 0.430
actin filament organization GO:0007015 113 0.428
positive regulation of protein modification process GO:0031401 299 0.427
Mouse
developmental cell growth GO:0048588 84 0.425
Mouse
regulation of actin filament based process GO:0032970 99 0.421
cell substrate adhesion GO:0031589 130 0.419
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.413
ensheathment of neurons GO:0007272 76 0.411
negative regulation of cell development GO:0010721 169 0.411
Mouse
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.403
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.402
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.396
regulation of cellular response to growth factor stimulus GO:0090287 82 0.391
regulation of secretion by cell GO:1903530 249 0.391
phosphatidylinositol mediated signaling GO:0048015 41 0.390
cell cell adhesion GO:0098609 41 0.389
regulation of osteoblast proliferation GO:0033688 15 0.386
somite development GO:0061053 81 0.382
neuron migration GO:0001764 122 0.378
stem cell maintenance GO:0019827 130 0.374
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.373
gastrulation GO:0007369 116 0.372
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.371
positive regulation of jnk cascade GO:0046330 46 0.369
jnk cascade GO:0007254 72 0.364
vagus nerve morphogenesis GO:0021644 2 0.362
wnt signaling pathway GO:0016055 188 0.361
rac protein signal transduction GO:0016601 13 0.360
cellular response to growth factor stimulus GO:0071363 197 0.360
regulation of protein serine threonine kinase activity GO:0071900 157 0.350
peptidyl serine phosphorylation GO:0018105 74 0.349
regulation of bmp signaling pathway GO:0030510 60 0.348
retinal blood vessel morphogenesis GO:0061304 3 0.347
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.340
Mouse
positive regulation of secretion by cell GO:1903532 114 0.338
cell fate commitment GO:0045165 210 0.333
canonical wnt signaling pathway GO:0060070 130 0.331
regulation of cellular amino acid metabolic process GO:0006521 5 0.327
establishment of tissue polarity GO:0007164 28 0.325
establishment of planar polarity GO:0001736 28 0.324
muscular septum morphogenesis GO:0003150 4 0.324
ventral trunk neural crest cell migration GO:0036486 4 0.324
Mouse
adult walking behavior GO:0007628 41 0.324
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.323
cardiac chamber morphogenesis GO:0003206 93 0.320
striated muscle tissue development GO:0014706 293 0.316
negative regulation of molecular function GO:0044092 258 0.315
Mouse
regulation of jnk cascade GO:0046328 62 0.314
ribonucleotide metabolic process GO:0009259 291 0.310
Mouse
mesenchymal cell development GO:0014031 93 0.307
Mouse
facioacoustic ganglion development GO:1903375 3 0.307
Mouse
regulation of hormone secretion GO:0046883 88 0.303
positive regulation of map kinase activity GO:0043406 84 0.303
regulation of establishment of planar polarity GO:0090175 28 0.301
pyramidal neuron development GO:0021860 8 0.300
regulation of cytokine secretion GO:0050707 61 0.298
cellular ketone metabolic process GO:0042180 84 0.296
negative regulation of catenin import into nucleus GO:0035414 2 0.294
cerebellum development GO:0021549 77 0.294
Mouse
regulation of rac gtpase activity GO:0032314 13 0.293
outflow tract morphogenesis GO:0003151 53 0.292
sympathetic neuron projection guidance GO:0097491 4 0.291
Mouse
neuronal action potential GO:0019228 54 0.290
regulation of body fluid levels GO:0050878 162 0.289
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.286
positive regulation of binding GO:0051099 49 0.284
action potential GO:0001508 78 0.283
development of primary sexual characteristics GO:0045137 143 0.283
Mouse Worm
germ cell development GO:0007281 185 0.282
maintenance of cell number GO:0098727 3 0.280
camera type eye development GO:0043010 266 0.280
regulation of mapk cascade GO:0043408 248 0.274
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.270
regulation of angiogenesis GO:0045765 81 0.268
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.268
neural crest cell differentiation GO:0014033 54 0.267
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.265
Mouse
myeloid cell differentiation GO:0030099 233 0.262
regulation of protein localization GO:0032880 231 0.261
regulation of actin filament bundle assembly GO:0032231 18 0.257
digestive tract morphogenesis GO:0048546 147 0.256
nucleoside catabolic process GO:0009164 206 0.255
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.253
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.252
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.252
nitrogen compound transport GO:0071705 271 0.249
cytokine production GO:0001816 319 0.248
regulation of transferase activity GO:0051338 263 0.244
digestive tract development GO:0048565 190 0.244
peptide transport GO:0015833 133 0.242
peptidyl serine modification GO:0018209 83 0.242
cardiocyte differentiation GO:0035051 87 0.242
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.239
regulation of cell substrate adhesion GO:0010810 73 0.239
regulation of peptide transport GO:0090087 91 0.239
glial cell development GO:0021782 54 0.238
regulation of synapse assembly GO:0051963 29 0.237
muscle tissue development GO:0060537 308 0.237
regulation of cardiac muscle tissue development GO:0055024 31 0.236
positive regulation of mapk cascade GO:0043410 170 0.230
circulatory system process GO:0003013 197 0.227
Mouse
t cell differentiation GO:0030217 174 0.224
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.222
non canonical wnt signaling pathway GO:0035567 33 0.222
regulation of canonical wnt signaling pathway GO:0060828 82 0.221
regulation of reproductive process GO:2000241 66 0.220
Mouse
fasciculation of sensory neuron axon GO:0097155 3 0.220
hormone secretion GO:0046879 128 0.220
negative regulation of cell migration GO:0030336 59 0.219
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.219
regulation of endothelial cell migration GO:0010594 22 0.218
Mouse
neural crest cell development GO:0014032 48 0.217
Mouse
epithelial cell development GO:0002064 159 0.216
negative regulation of hydrolase activity GO:0051346 71 0.216
Mouse
regulation of catenin import into nucleus GO:0035412 5 0.215
cell type specific apoptotic process GO:0097285 268 0.214
insulin secretion GO:0030073 89 0.214
regulation of cell growth GO:0001558 91 0.214
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.213
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.212
cardiac septum development GO:0003279 59 0.210
cell growth GO:0016049 130 0.210
Mouse
cytoplasmic transport GO:0016482 234 0.210
positive regulation of programmed cell death GO:0043068 218 0.210
retina development in camera type eye GO:0060041 119 0.208
regulation of system process GO:0044057 200 0.206
Mouse
positive regulation of synapse assembly GO:0051965 18 0.206
t cell activation GO:0042110 289 0.205
Mouse
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.204
skin development GO:0043588 220 0.204
epithelial tube formation GO:0072175 130 0.203
Mouse
commissural neuron axon guidance GO:0071679 8 0.203
regulation of wnt signaling pathway GO:0030111 123 0.202
regulation of protein geranylgeranylation GO:2000539 2 0.202
regulation of cell cycle GO:0051726 281 0.201
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.200
lens morphogenesis in camera type eye GO:0002089 24 0.198
peptide secretion GO:0002790 114 0.197
fasciculation of motor neuron axon GO:0097156 2 0.197
formation of primary germ layer GO:0001704 77 0.197
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.197
trigeminal nerve structural organization GO:0021637 6 0.197
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.195
response to growth factor GO:0070848 198 0.193
cellular homeostasis GO:0019725 240 0.192
inositol lipid mediated signaling GO:0048017 41 0.191
regulation of cytokine production GO:0001817 266 0.191
regulation of muscle tissue development GO:1901861 97 0.191
axial mesoderm formation GO:0048320 3 0.190
regulation of jun kinase activity GO:0043506 40 0.189
positive regulation of secretion GO:0051047 130 0.188
regulation of neuron projection regeneration GO:0070570 7 0.187
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.187
negative regulation of neuron apoptotic process GO:0043524 92 0.187
transmission of nerve impulse GO:0019226 76 0.185
lens development in camera type eye GO:0002088 62 0.183
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.183
connective tissue development GO:0061448 179 0.181
learning or memory GO:0007611 148 0.180
cardiac muscle cell differentiation GO:0055007 69 0.178
protein catabolic process GO:0030163 221 0.178
t cell differentiation in thymus GO:0033077 77 0.177
negative regulation of neuron projection regeneration GO:0070571 3 0.176
organonitrogen compound biosynthetic process GO:1901566 192 0.175
negative regulation of protein modification process GO:0031400 163 0.175
Mouse
positive regulation of lipid kinase activity GO:0090218 11 0.174
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.169
trabecula morphogenesis GO:0061383 40 0.168
Mouse
membrane organization GO:0061024 245 0.167
positive regulation of kinase activity GO:0033674 155 0.167
muscle system process GO:0003012 141 0.167
muscle cell differentiation GO:0042692 261 0.166
Mouse
labyrinthine layer blood vessel development GO:0060716 21 0.166
regulation of endopeptidase activity GO:0052548 89 0.165
corpus callosum development GO:0022038 10 0.164
regulation of map kinase activity GO:0043405 120 0.163
skeletal muscle organ development GO:0060538 163 0.162
oligodendrocyte differentiation GO:0048709 53 0.162
adult behavior GO:0030534 135 0.159
cerebral cortex cell migration GO:0021795 44 0.158
Mouse
gonad development GO:0008406 141 0.157
Mouse Worm
b cell activation GO:0042113 161 0.155
multicellular organismal signaling GO:0035637 91 0.155
neural crest cell migration GO:0001755 32 0.154
Mouse
protein localization to plasma membrane GO:0072659 57 0.154
amide transport GO:0042886 138 0.153
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.153
negative regulation of protein phosphorylation GO:0001933 126 0.152
Mouse
cardiac chamber development GO:0003205 108 0.151
synaptic transmission GO:0007268 329 0.151
cardiac muscle tissue development GO:0048738 130 0.151
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.151
telencephalon cell migration GO:0022029 55 0.149
Mouse
establishment of protein localization to organelle GO:0072594 118 0.148
regulation of cysteine type endopeptidase activity GO:2000116 65 0.147
regulation of heart contraction GO:0008016 77 0.147
Mouse
spinal cord development GO:0021510 81 0.147
regulation of stem cell differentiation GO:2000736 50 0.146
adult locomotory behavior GO:0008344 91 0.145
peptidyl tyrosine modification GO:0018212 145 0.144
Mouse
ear development GO:0043583 200 0.143
positive regulation of protein secretion GO:0050714 52 0.143
protein localization to nucleus GO:0034504 121 0.143
mesoderm development GO:0007498 100 0.142
positive regulation of actin filament bundle assembly GO:0032233 11 0.142
regulation of blood circulation GO:1903522 93 0.141
Mouse
notochord formation GO:0014028 5 0.139
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.139
negative regulation of protein metabolic process GO:0051248 282 0.138
Mouse
glycoprotein metabolic process GO:0009100 116 0.137
lipid biosynthetic process GO:0008610 179 0.136
regulation of multi organism process GO:0043900 111 0.136
catenin import into nucleus GO:0035411 6 0.135
dorsal ventral axon guidance GO:0033563 3 0.134
negative regulation of wnt signaling pathway GO:0030178 73 0.134
lymphocyte differentiation GO:0030098 242 0.134
Mouse
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.134
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.134
eye photoreceptor cell differentiation GO:0001754 41 0.133
branchiomotor neuron axon guidance GO:0021785 7 0.133
Mouse
axon regeneration GO:0031103 12 0.133
multi organism reproductive behavior GO:0044705 29 0.132
mammary gland epithelium development GO:0061180 65 0.132
peptidyl tyrosine phosphorylation GO:0018108 143 0.131
Mouse
immune effector process GO:0002252 321 0.131
Mouse
female gamete generation GO:0007292 74 0.131
smooth muscle cell migration GO:0014909 10 0.130
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.130
negative regulation of phosphate metabolic process GO:0045936 184 0.129
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.129
regulation of cellular component biogenesis GO:0044087 181 0.129
metal ion homeostasis GO:0055065 189 0.128
cation homeostasis GO:0055080 212 0.128
regulation of peptide secretion GO:0002791 77 0.126
cardiac ventricle development GO:0003231 83 0.125
neuromuscular process GO:0050905 99 0.125
Fly
cell fate specification GO:0001708 72 0.125
regulation of proteolysis GO:0030162 164 0.125
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.124
Mouse
regulation of membrane potential GO:0042391 192 0.124
respiratory system development GO:0060541 190 0.123
blastocyst development GO:0001824 80 0.123
mesodermal cell migration GO:0008078 4 0.123
positive regulation of stress activated mapk cascade GO:0032874 48 0.123
negative regulation of neuron death GO:1901215 98 0.122

Sema6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org