Mus musculus

0 known processes

Rapgefl1

Rap guanine nucleotide exchange factor (GEF)-like 1

(Aliases: B230105J10)

Rapgefl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 266 0.153
inorganic cation transmembrane transport GO:0098662 207 0.115
regulation of cellular amine metabolic process GO:0033238 20 0.110
cation transport GO:0006812 399 0.103
amine metabolic process GO:0009308 45 0.102
regulation of cellular amino acid metabolic process GO:0006521 5 0.084
ion transmembrane transport GO:0034220 361 0.081
cellular amine metabolic process GO:0044106 44 0.081
inorganic ion transmembrane transport GO:0098660 234 0.074
transmembrane transport GO:0055085 412 0.061
cellular amino acid metabolic process GO:0006520 103 0.059
cellular ketone metabolic process GO:0042180 84 0.059
peptidyl amino acid modification GO:0018193 336 0.058
ras protein signal transduction GO:0007265 77 0.057
regulation of cell projection organization GO:0031344 206 0.054
small gtpase mediated signal transduction GO:0007264 97 0.053
membrane organization GO:0061024 245 0.052
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
nucleoside phosphate metabolic process GO:0006753 338 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.050
regulation of organelle organization GO:0033043 289 0.050
synaptic transmission GO:0007268 329 0.050
regulation of cellular catabolic process GO:0031329 242 0.048
aromatic compound catabolic process GO:0019439 286 0.046
cellular lipid metabolic process GO:0044255 323 0.046
nucleoside catabolic process GO:0009164 206 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
heterocycle catabolic process GO:0046700 280 0.043
organic cyclic compound catabolic process GO:1901361 295 0.043
carbohydrate derivative catabolic process GO:1901136 231 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.041
endomembrane system organization GO:0010256 147 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
carbohydrate derivative biosynthetic process GO:1901137 183 0.039
macromolecule catabolic process GO:0009057 281 0.039
regulation of cellular component biogenesis GO:0044087 181 0.039
regulation of cellular component size GO:0032535 121 0.038
nucleotide metabolic process GO:0009117 332 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.037
purine nucleoside triphosphate catabolic process GO:0009146 203 0.037
purine containing compound catabolic process GO:0072523 213 0.035
purine containing compound metabolic process GO:0072521 311 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
response to radiation GO:0009314 165 0.035
negative regulation of cellular component organization GO:0051129 194 0.035
ribonucleoside metabolic process GO:0009119 245 0.034
nucleoside metabolic process GO:0009116 246 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
muscle system process GO:0003012 141 0.033
protein localization to membrane GO:0072657 108 0.033
myeloid cell differentiation GO:0030099 233 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
regulation of ion transport GO:0043269 215 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
regulation of membrane potential GO:0042391 192 0.032
divalent inorganic cation transport GO:0072511 178 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.031
developmental maturation GO:0021700 193 0.031
regulation of kinase activity GO:0043549 249 0.031
organophosphate catabolic process GO:0046434 232 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
actin cytoskeleton organization GO:0030036 220 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
protein catabolic process GO:0030163 221 0.030
carbohydrate metabolic process GO:0005975 230 0.030
oxidation reduction process GO:0055114 342 0.030
rho protein signal transduction GO:0007266 32 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
regulation of purine nucleotide catabolic process GO:0033121 122 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
axonogenesis GO:0007409 274 0.029
protein localization to plasma membrane GO:0072659 57 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.028
cytokine production GO:0001816 319 0.028
cellular ion homeostasis GO:0006873 165 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.027
positive regulation of protein modification process GO:0031401 299 0.027
positive regulation of cellular catabolic process GO:0031331 148 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
regulation of secretion GO:0051046 274 0.027
regulation of anatomical structure size GO:0090066 178 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
cellular homeostasis GO:0019725 240 0.026
plasma membrane organization GO:0007009 90 0.026
regulation of neuron projection development GO:0010975 169 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
regulation of secretion by cell GO:1903530 249 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
regulation of cytoskeleton organization GO:0051493 122 0.025
cellular chemical homeostasis GO:0055082 215 0.025
muscle cell differentiation GO:0042692 261 0.025
cell adhesion GO:0007155 329 0.025
regulation of cell adhesion GO:0030155 154 0.025
dna metabolic process GO:0006259 303 0.025
multicellular organismal homeostasis GO:0048871 164 0.025
divalent inorganic cation homeostasis GO:0072507 138 0.025
regulation of transmembrane transport GO:0034762 128 0.024
response to organonitrogen compound GO:0010243 246 0.024
nucleotide catabolic process GO:0009166 217 0.024
actin filament organization GO:0007015 113 0.024
regulation of gtp catabolic process GO:0033124 113 0.024
regulation of actin cytoskeleton organization GO:0032956 84 0.024
regulation of hydrolase activity GO:0051336 246 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
regulation of feeding behavior GO:0060259 3 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
regulation of neuron differentiation GO:0045664 281 0.024
ribonucleotide catabolic process GO:0009261 208 0.023
calcium ion homeostasis GO:0055074 127 0.023
cation homeostasis GO:0055080 212 0.023
cytoplasmic transport GO:0016482 234 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.023
positive regulation of organelle organization GO:0010638 128 0.023
nuclear division GO:0000280 158 0.022
maintenance of location GO:0051235 89 0.022
leukocyte differentiation GO:0002521 342 0.022
modification dependent macromolecule catabolic process GO:0043632 133 0.022
lipid localization GO:0010876 126 0.022
nitrogen compound transport GO:0071705 271 0.022
amide transport GO:0042886 138 0.022
phospholipid metabolic process GO:0006644 87 0.022
gland development GO:0048732 330 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.021
compound eye development GO:0048749 1 0.021
regulation of cellular response to stress GO:0080135 159 0.021
mitochondrion distribution GO:0048311 4 0.021
calcium ion transmembrane transport GO:0070588 85 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
immune effector process GO:0002252 321 0.021
regulation of transferase activity GO:0051338 263 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of ion transmembrane transport GO:0034765 119 0.020
regulation of ion transmembrane transporter activity GO:0032412 54 0.020
cognition GO:0050890 149 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.020
divalent metal ion transport GO:0070838 172 0.020
positive regulation of transferase activity GO:0051347 167 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
mapk cascade GO:0000165 281 0.020
negative regulation of protein modification process GO:0031400 163 0.020
regulation of engulfment of apoptotic cell GO:1901074 2 0.020
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.020
gtp metabolic process GO:0046039 144 0.020
anatomical structure homeostasis GO:0060249 145 0.020
guanosine containing compound metabolic process GO:1901068 144 0.020
negative regulation of immune system process GO:0002683 209 0.020
activation of meiosis involved in egg activation GO:0060466 2 0.020
cellular protein catabolic process GO:0044257 155 0.020
regulation of hormone levels GO:0010817 211 0.020
positive regulation of nervous system development GO:0051962 221 0.020
organelle fission GO:0048285 170 0.020
b cell activation GO:0042113 161 0.020
glycoprotein metabolic process GO:0009100 116 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
synapse organization GO:0050808 125 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
single organism cell adhesion GO:0098602 156 0.019
response to light stimulus GO:0009416 135 0.019
positive regulation of cell development GO:0010720 237 0.019
skin development GO:0043588 220 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
epidermis development GO:0008544 187 0.019
blood circulation GO:0008015 195 0.019
regulation of cell cycle process GO:0010564 160 0.019
guanosine containing compound catabolic process GO:1901069 144 0.019
calcium ion transport GO:0006816 159 0.018
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.018
epithelial cell proliferation GO:0050673 174 0.018
muscle tissue development GO:0060537 308 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
peptide transport GO:0015833 133 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
rac protein signal transduction GO:0016601 13 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
digestive system development GO:0055123 200 0.018
organic anion transport GO:0015711 137 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
peptidyl tyrosine phosphorylation GO:0018108 143 0.018
regulation of actin filament based process GO:0032970 99 0.018
regulation of protein kinase activity GO:0045859 232 0.018
intracellular protein transport GO:0006886 204 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
lymphocyte proliferation GO:0046651 164 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
cell fate commitment GO:0045165 210 0.017
anion transport GO:0006820 177 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
actin polymerization or depolymerization GO:0008154 54 0.017
exocytosis GO:0006887 121 0.017
regulation of cell motility GO:2000145 236 0.017
negative regulation of molecular function GO:0044092 258 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
regulation of ras protein signal transduction GO:0046578 114 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
apoptotic signaling pathway GO:0097190 306 0.016
lipid transport GO:0006869 98 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
protein maturation GO:0051604 176 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
gtp catabolic process GO:0006184 143 0.016
regulation of calcium ion transport GO:0051924 69 0.016
protein polymerization GO:0051258 57 0.016
feeding behavior GO:0007631 62 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.015
learning or memory GO:0007611 148 0.015
formation of organ boundary GO:0010160 1 0.015
positive regulation of kinase activity GO:0033674 155 0.015
chromatin modification GO:0016568 187 0.015
homeostasis of number of cells GO:0048872 210 0.015
circulatory system process GO:0003013 197 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
myotube differentiation GO:0014902 105 0.015
wound healing GO:0042060 157 0.015
regulation of protein complex assembly GO:0043254 83 0.015
metal ion homeostasis GO:0055065 189 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
lateral inhibition GO:0046331 1 0.015
regulation of cell growth GO:0001558 91 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
protein localization to organelle GO:0033365 185 0.015
regulation of cell cycle GO:0051726 281 0.015
mitotic cell cycle GO:0000278 195 0.015
regulation of system process GO:0044057 200 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
memory GO:0007613 58 0.014
leukocyte migration GO:0050900 124 0.014
regulation of metal ion transport GO:0010959 106 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.014
regulation of proteolysis GO:0030162 164 0.014
regulation of transporter activity GO:0032409 57 0.014
endocytosis GO:0006897 168 0.014
rhythmic process GO:0048511 174 0.014
multicellular organismal signaling GO:0035637 91 0.014
actin filament polymerization GO:0030041 44 0.014
heart morphogenesis GO:0003007 178 0.014
negative regulation of organelle organization GO:0010639 90 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
male gamete generation GO:0048232 285 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
dendrite development GO:0016358 115 0.014
rap protein signal transduction GO:0032486 3 0.014
regulation of cell size GO:0008361 72 0.014
ossification GO:0001503 216 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
activation of immune response GO:0002253 138 0.014
sensory perception GO:0007600 245 0.014
t cell activation GO:0042110 289 0.014
cell growth GO:0016049 130 0.014
mitotic cell cycle process GO:1903047 159 0.014
carboxylic acid transport GO:0046942 100 0.014
response to inorganic substance GO:0010035 96 0.014
glucose homeostasis GO:0042593 128 0.014
transmission of nerve impulse GO:0019226 76 0.014
regulation of protein catabolic process GO:0042176 108 0.014
tissue homeostasis GO:0001894 115 0.014
positive regulation of cell death GO:0010942 224 0.014
epithelial cell development GO:0002064 159 0.014
fat cell differentiation GO:0045444 160 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
carbohydrate homeostasis GO:0033500 128 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
cell substrate adhesion GO:0031589 130 0.013
positive regulation of ion transport GO:0043270 65 0.013
hexose metabolic process GO:0019318 98 0.013
protein processing GO:0016485 163 0.013
organelle assembly GO:0070925 177 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
chemotaxis GO:0006935 247 0.013
peptidyl serine phosphorylation GO:0018105 74 0.013
muscle fiber development GO:0048747 76 0.013
striated muscle tissue development GO:0014706 293 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
response to oxidative stress GO:0006979 123 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
peptide hormone secretion GO:0030072 109 0.013
organic acid transport GO:0015849 101 0.013
covalent chromatin modification GO:0016569 163 0.013
dephosphorylation GO:0016311 129 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
regulation of cell migration GO:0030334 219 0.013
muscle contraction GO:0006936 101 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
sensory organ morphogenesis GO:0090596 242 0.013
peptide secretion GO:0002790 114 0.013
vesicle localization GO:0051648 86 0.013
intracellular mrna localization GO:0008298 4 0.013
lipid biosynthetic process GO:0008610 179 0.013
locomotory behavior GO:0007626 195 0.013
regulation of homeostatic process GO:0032844 182 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of mapk cascade GO:0043408 248 0.013
response to growth factor GO:0070848 198 0.013
skeletal system development GO:0001501 356 0.012
chromatin organization GO:0006325 206 0.012
regulation of cd24 biosynthetic process GO:2000559 1 0.012
fertilization GO:0009566 127 0.012
peptidyl serine modification GO:0018209 83 0.012
cell activation involved in immune response GO:0002263 126 0.012
camera type eye development GO:0043010 266 0.012
protein ubiquitination GO:0016567 171 0.012
angiogenesis GO:0001525 201 0.012
regionalization GO:0003002 337 0.012
cell maturation GO:0048469 127 0.012
glucose metabolic process GO:0006006 92 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
protein targeting GO:0006605 143 0.012
organelle localization GO:0051640 179 0.012
lymphocyte differentiation GO:0030098 242 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
fatty acid metabolic process GO:0006631 121 0.012
response to acid chemical GO:0001101 111 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of chromosome organization GO:0033044 83 0.012
sulfur compound metabolic process GO:0006790 100 0.012
action potential GO:0001508 78 0.012
leukocyte proliferation GO:0070661 172 0.012
protein localization to nucleus GO:0034504 121 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
blood vessel morphogenesis GO:0048514 285 0.012
hormone secretion GO:0046879 128 0.012
positive regulation of secretion GO:0051047 130 0.012
methylation GO:0032259 134 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
negative regulation of growth GO:0045926 99 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of cytokine production GO:0001817 266 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
telencephalon development GO:0021537 186 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
oocyte construction GO:0007308 2 0.011
establishment of organelle localization GO:0051656 122 0.011
establishment of vesicle localization GO:0051650 81 0.011
macromolecule glycosylation GO:0043413 55 0.011
nuclear transport GO:0051169 139 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
monosaccharide metabolic process GO:0005996 106 0.011
histone modification GO:0016570 159 0.011
cytokinetic process GO:0032506 2 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
striated muscle cell development GO:0055002 125 0.011
cellular response to lipid GO:0071396 145 0.011
oocyte axis specification GO:0007309 2 0.011
meiotic nuclear division GO:0007126 115 0.011
peptidyl lysine modification GO:0018205 77 0.011
positive regulation of cell cycle GO:0045787 92 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
stress activated mapk cascade GO:0051403 80 0.010
cell division GO:0051301 120 0.010
alcohol metabolic process GO:0006066 116 0.010
nuclear import GO:0051170 95 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
osteoclast differentiation GO:0030316 62 0.010
response to lipopolysaccharide GO:0032496 128 0.010
digestive tract development GO:0048565 190 0.010
activation of meiosis GO:0090427 4 0.010
axon guidance GO:0007411 141 0.010
ameboidal type cell migration GO:0001667 128 0.010
response to organic cyclic compound GO:0014070 198 0.010
positive regulation of creb transcription factor activity GO:0032793 4 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
regulation of body fluid levels GO:0050878 162 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
regulation of jnk cascade GO:0046328 62 0.010
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.010
vesicle organization GO:0016050 60 0.010

Rapgefl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.013
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.012
connective tissue disease DOID:65 0 0.011