Mus musculus

20 known processes

Lrrn4

leucine rich repeat neuronal 4

(Aliases: B430119L13Rik,Nlrr4)

Lrrn4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.060
transmembrane transport GO:0055085 412 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
regulation of cellular amine metabolic process GO:0033238 20 0.044
nucleotide metabolic process GO:0009117 332 0.044
nucleobase containing small molecule metabolic process GO:0055086 352 0.044
ion transmembrane transport GO:0034220 361 0.043
cation transport GO:0006812 399 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.040
amine metabolic process GO:0009308 45 0.040
apoptotic signaling pathway GO:0097190 306 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
cellular ketone metabolic process GO:0042180 84 0.037
ribonucleotide metabolic process GO:0009259 291 0.036
purine nucleoside metabolic process GO:0042278 241 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
purine containing compound metabolic process GO:0072521 311 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.034
organic cyclic compound catabolic process GO:1901361 295 0.033
peptidyl amino acid modification GO:0018193 336 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
protein maturation GO:0051604 176 0.032
aromatic compound catabolic process GO:0019439 286 0.032
macromolecule catabolic process GO:0009057 281 0.031
ribose phosphate metabolic process GO:0019693 291 0.030
regulation of system process GO:0044057 200 0.030
negative regulation of molecular function GO:0044092 258 0.030
cell adhesion GO:0007155 329 0.030
nucleoside metabolic process GO:0009116 246 0.030
cellular lipid metabolic process GO:0044255 323 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.029
dna metabolic process GO:0006259 303 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
epithelial tube morphogenesis GO:0060562 303 0.029
heterocycle catabolic process GO:0046700 280 0.029
small gtpase mediated signal transduction GO:0007264 97 0.028
synaptic transmission GO:0007268 329 0.028
regulation of hydrolase activity GO:0051336 246 0.028
cation transmembrane transport GO:0098655 266 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
meiotic nuclear division GO:0007126 115 0.027
inflammatory response GO:0006954 244 0.027
ras protein signal transduction GO:0007265 77 0.027
muscle system process GO:0003012 141 0.027
anion transport GO:0006820 177 0.026
positive regulation of protein modification process GO:0031401 299 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of mapk cascade GO:0043408 248 0.026
ribonucleoside metabolic process GO:0009119 245 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
placenta development GO:0001890 140 0.025
cation homeostasis GO:0055080 212 0.025
organelle fission GO:0048285 170 0.025
protein catabolic process GO:0030163 221 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
regulation of cell activation GO:0050865 289 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
urogenital system development GO:0001655 261 0.025
regulation of homeostatic process GO:0032844 182 0.024
cytoplasmic transport GO:0016482 234 0.024
nuclear division GO:0000280 158 0.024
blood vessel morphogenesis GO:0048514 285 0.024
spermatogenesis GO:0007283 284 0.024
muscle cell differentiation GO:0042692 261 0.024
metal ion homeostasis GO:0055065 189 0.024
regulation of organelle organization GO:0033043 289 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
renal system development GO:0072001 225 0.023
regulation of cytokine production GO:0001817 266 0.023
purine containing compound catabolic process GO:0072523 213 0.023
circulatory system process GO:0003013 197 0.022
male gamete generation GO:0048232 285 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
nitrogen compound transport GO:0071705 271 0.022
mapk cascade GO:0000165 281 0.022
immune effector process GO:0002252 321 0.022
meiotic cell cycle GO:0051321 122 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
angiogenesis GO:0001525 201 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
nucleoside catabolic process GO:0009164 206 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
regulation of protein localization GO:0032880 231 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
rho protein signal transduction GO:0007266 32 0.021
skeletal system development GO:0001501 356 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
oxidation reduction process GO:0055114 342 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
protein ubiquitination GO:0016567 171 0.020
small molecule biosynthetic process GO:0044283 132 0.020
organophosphate catabolic process GO:0046434 232 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
wnt signaling pathway GO:0016055 188 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
regulation of kinase activity GO:0043549 249 0.020
regulation of membrane potential GO:0042391 192 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
epithelial cell proliferation GO:0050673 174 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
cellular chemical homeostasis GO:0055082 215 0.019
cellular homeostasis GO:0019725 240 0.019
negative regulation of protein modification process GO:0031400 163 0.019
response to radiation GO:0009314 165 0.019
t cell activation GO:0042110 289 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
cellular ion homeostasis GO:0006873 165 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
nucleotide catabolic process GO:0009166 217 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
lymphocyte differentiation GO:0030098 242 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of cell motility GO:2000145 236 0.019
action potential GO:0001508 78 0.019
leukocyte differentiation GO:0002521 342 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
locomotory behavior GO:0007626 195 0.018
kidney development GO:0001822 213 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
divalent inorganic cation transport GO:0072511 178 0.018
protein processing GO:0016485 163 0.018
cytokine production GO:0001816 319 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
regulation of cell cycle GO:0051726 281 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of secretion GO:0051046 274 0.018
forebrain development GO:0030900 302 0.018
fertilization GO:0009566 127 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
cellular protein catabolic process GO:0044257 155 0.017
blood circulation GO:0008015 195 0.017
regionalization GO:0003002 337 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
transmission of nerve impulse GO:0019226 76 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
methylation GO:0032259 134 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
endocytosis GO:0006897 168 0.017
ossification GO:0001503 216 0.017
leukocyte proliferation GO:0070661 172 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
intracellular protein transport GO:0006886 204 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of reproductive process GO:2000241 66 0.016
covalent chromatin modification GO:0016569 163 0.016
chromatin organization GO:0006325 206 0.016
regulation of protein kinase activity GO:0045859 232 0.016
sequestering of metal ion GO:0051238 19 0.016
glycoprotein metabolic process GO:0009100 116 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
regulation of ion transport GO:0043269 215 0.016
negative regulation of defense response GO:0031348 77 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of defense response GO:0031347 233 0.015
organic anion transport GO:0015711 137 0.015
regulation of cell migration GO:0030334 219 0.015
lipid biosynthetic process GO:0008610 179 0.015
regulation of multi organism process GO:0043900 111 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
male meiosis GO:0007140 37 0.015
homeostasis of number of cells GO:0048872 210 0.015
amide transport GO:0042886 138 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
germ cell development GO:0007281 185 0.015
sensory perception GO:0007600 245 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
regulation of response to wounding GO:1903034 189 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
divalent metal ion transport GO:0070838 172 0.015
respiratory system development GO:0060541 190 0.015
heart contraction GO:0060047 93 0.015
multicellular organismal signaling GO:0035637 91 0.014
regulation of transmembrane transport GO:0034762 128 0.014
response to organic cyclic compound GO:0014070 198 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
sequestering of calcium ion GO:0051208 18 0.014
meiosis i GO:0007127 60 0.014
exocytosis GO:0006887 121 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of anatomical structure size GO:0090066 178 0.014
regulation of body fluid levels GO:0050878 162 0.014
organelle localization GO:0051640 179 0.014
muscle contraction GO:0006936 101 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
wound healing GO:0042060 157 0.014
neural tube development GO:0021915 160 0.014
regulation of t cell activation GO:0050863 170 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
response to organonitrogen compound GO:0010243 246 0.014
regulation of gtp catabolic process GO:0033124 113 0.014
myosin filament organization GO:0031033 3 0.014
cellular protein complex assembly GO:0043623 116 0.014
negative regulation of immune system process GO:0002683 209 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
lung development GO:0030324 164 0.014
stem cell differentiation GO:0048863 268 0.014
response to extracellular stimulus GO:0009991 127 0.014
oocyte construction GO:0007308 2 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
regulation of chloride transport GO:2001225 2 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.013
positive regulation of cytokine production GO:0001819 174 0.013
cell division GO:0051301 120 0.013
regulation of secretion by cell GO:1903530 249 0.013
striated muscle tissue development GO:0014706 293 0.013
mitotic cell cycle process GO:1903047 159 0.013
calcium ion transport GO:0006816 159 0.013
myosin filament assembly GO:0031034 2 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
cell activation involved in immune response GO:0002263 126 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
microtubule based process GO:0007017 236 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
macromolecule methylation GO:0043414 120 0.013
mitotic cell cycle GO:0000278 195 0.013
response to growth factor GO:0070848 198 0.013
developmental maturation GO:0021700 193 0.013
positive regulation of cell death GO:0010942 224 0.013
lymphocyte proliferation GO:0046651 164 0.013
response to oxidative stress GO:0006979 123 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
skeletal system morphogenesis GO:0048705 203 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
sulfur compound metabolic process GO:0006790 100 0.013
histone modification GO:0016570 159 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of hormone levels GO:0010817 211 0.013
extracellular matrix organization GO:0030198 147 0.013
single organism cell adhesion GO:0098602 156 0.013
gland development GO:0048732 330 0.013
bone development GO:0060348 120 0.013
muscle tissue development GO:0060537 308 0.013
lymphocyte mediated immunity GO:0002449 139 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
regulation of cell cycle process GO:0010564 160 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
response to acid chemical GO:0001101 111 0.012
organic acid transport GO:0015849 101 0.012
striated muscle myosin thick filament assembly GO:0071688 1 0.012
epithelial cell development GO:0002064 159 0.012
neural tube formation GO:0001841 108 0.012
maintenance of location GO:0051235 89 0.012
regulation of ossification GO:0030278 112 0.012
t cell differentiation GO:0030217 174 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of protein processing GO:0070613 96 0.012
positive regulation of cell development GO:0010720 237 0.012
meiotic cell cycle process GO:1903046 77 0.012
cellular response to lipid GO:0071396 145 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
protein localization to organelle GO:0033365 185 0.012
positive regulation of cell activation GO:0050867 158 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
neuron death GO:0070997 154 0.012
potassium ion homeostasis GO:0055075 4 0.012
heart morphogenesis GO:0003007 178 0.012
response to nutrient levels GO:0031667 109 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
regulation of protein maturation GO:1903317 96 0.012
positive regulation of cellular ph reduction GO:0032849 2 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
protein secretion GO:0009306 111 0.012
oocyte axis specification GO:0007309 2 0.012
compound eye development GO:0048749 1 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
mesodermal cell migration GO:0008078 4 0.012
negative regulation of cell cycle GO:0045786 123 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
b cell activation GO:0042113 161 0.011
regulation of protein catabolic process GO:0042176 108 0.011
tube formation GO:0035148 140 0.011
multi multicellular organism process GO:0044706 109 0.011
gliogenesis GO:0042063 141 0.011
gtp metabolic process GO:0046039 144 0.011
rap protein signal transduction GO:0032486 3 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
rhythmic process GO:0048511 174 0.011
fatty acid metabolic process GO:0006631 121 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
positive regulation of cell substrate adhesion GO:0010811 47 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
membrane organization GO:0061024 245 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
negative regulation of phospholipase activity GO:0010519 4 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
positive regulation of kinase activity GO:0033674 155 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
organic acid biosynthetic process GO:0016053 86 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
rna interference GO:0016246 2 0.011
negative regulation of protein maturation GO:1903318 79 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
activation of immune response GO:0002253 138 0.011
cognition GO:0050890 149 0.011
respiratory tube development GO:0030323 167 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
cofactor metabolic process GO:0051186 80 0.011
regulation of feeding behavior GO:0060259 3 0.011
chromatin modification GO:0016568 187 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
myeloid cell differentiation GO:0030099 233 0.011
regulation of inflammatory response GO:0050727 147 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
cardiac muscle contraction GO:0060048 32 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
carbohydrate homeostasis GO:0033500 128 0.011
carboxylic acid transport GO:0046942 100 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
neuron apoptotic process GO:0051402 142 0.011
dephosphorylation GO:0016311 129 0.011
regulation of proteolysis GO:0030162 164 0.011
single fertilization GO:0007338 82 0.011
neuronal action potential GO:0019228 54 0.011
rna processing GO:0006396 105 0.011
regulation of binding GO:0051098 111 0.011
positive regulation of transferase activity GO:0051347 167 0.010
regulation of neuron differentiation GO:0045664 281 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
ribonucleotide biosynthetic process GO:0009260 59 0.010
mesonephros development GO:0001823 97 0.010
epithelial tube formation GO:0072175 130 0.010
heart process GO:0003015 94 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
adult behavior GO:0030534 135 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
organ growth GO:0035265 117 0.010
midgut development GO:0007494 4 0.010
protein alkylation GO:0008213 81 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
response to lipopolysaccharide GO:0032496 128 0.010
intracellular distribution of mitochondria GO:0048312 1 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
single organismal cell cell adhesion GO:0016337 131 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
skeletal muscle organ development GO:0060538 163 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
anatomical structure homeostasis GO:0060249 145 0.010
interleukin 8 production GO:0032637 4 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
regulation of muscle system process GO:0090257 80 0.010
protein methylation GO:0006479 81 0.010
glucose homeostasis GO:0042593 128 0.010

Lrrn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.019
immune system disease DOID:2914 0 0.016
cardiovascular system disease DOID:1287 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
hematopoietic system disease DOID:74 0 0.012
inherited metabolic disorder DOID:655 0 0.012
musculoskeletal system disease DOID:17 0 0.012