Mus musculus

0 known processes

Pkd2l2

polycystic kidney disease 2-like 2

(Aliases: TRPP5)

Pkd2l2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male gamete generation GO:0048232 285 0.068
regulation of cellular amino acid metabolic process GO:0006521 5 0.067
cellular amine metabolic process GO:0044106 44 0.057
cellular amino acid metabolic process GO:0006520 103 0.054
amine metabolic process GO:0009308 45 0.053
transmembrane transport GO:0055085 412 0.052
Mouse Worm
ion transmembrane transport GO:0034220 361 0.050
Mouse Worm
spermatogenesis GO:0007283 284 0.048
macromolecule catabolic process GO:0009057 281 0.047
Mouse
cation transmembrane transport GO:0098655 266 0.046
Mouse Worm
regulation of cellular amine metabolic process GO:0033238 20 0.046
cation transport GO:0006812 399 0.045
Mouse Worm
t cell activation GO:0042110 289 0.042
cellular ketone metabolic process GO:0042180 84 0.041
dna metabolic process GO:0006259 303 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
Mouse
protein modification by small protein conjugation GO:0032446 187 0.035
peptidyl amino acid modification GO:0018193 336 0.035
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.035
Mouse Worm
inorganic cation transmembrane transport GO:0098662 207 0.034
Mouse Worm
protein ubiquitination GO:0016567 171 0.033
regulation of cytokine production GO:0001817 266 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.032
cytoplasmic transport GO:0016482 234 0.032
Mouse
leukocyte differentiation GO:0002521 342 0.032
negative regulation of immune system process GO:0002683 209 0.031
cytokine production GO:0001816 319 0.031
activation of immune response GO:0002253 138 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.028
immune effector process GO:0002252 321 0.028
germ cell development GO:0007281 185 0.028
protein catabolic process GO:0030163 221 0.027
Mouse
regulation of defense response GO:0031347 233 0.027
nucleotide metabolic process GO:0009117 332 0.027
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.027
regulation of organelle organization GO:0033043 289 0.027
Mouse
regulation of membrane potential GO:0042391 192 0.027
homeostasis of number of cells GO:0048872 210 0.026
spermatid differentiation GO:0048515 115 0.026
positive regulation of protein modification process GO:0031401 299 0.025
inflammatory response GO:0006954 244 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
regulation of cell activation GO:0050865 289 0.024
regulation of system process GO:0044057 200 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
Mouse
purine nucleotide metabolic process GO:0006163 302 0.023
Mouse
divalent metal ion transport GO:0070838 172 0.023
Mouse Worm
organonitrogen compound biosynthetic process GO:1901566 192 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
immune response regulating signaling pathway GO:0002764 125 0.023
regulation of transferase activity GO:0051338 263 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
regulation of protein transport GO:0051223 163 0.022
Mouse
cellular chemical homeostasis GO:0055082 215 0.022
Mouse
negative regulation of molecular function GO:0044092 258 0.022
Mouse
innate immune response GO:0045087 157 0.022
chemotaxis GO:0006935 247 0.022
regulation of cell cycle GO:0051726 281 0.022
Mouse
carbohydrate metabolic process GO:0005975 230 0.022
purine containing compound metabolic process GO:0072521 311 0.022
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
regulation of cell projection organization GO:0031344 206 0.022
organelle fission GO:0048285 170 0.022
nuclear division GO:0000280 158 0.022
lymphocyte differentiation GO:0030098 242 0.022
intracellular protein transport GO:0006886 204 0.021
Mouse
myeloid cell differentiation GO:0030099 233 0.021
spermatid development GO:0007286 108 0.021
regulation of neuron differentiation GO:0045664 281 0.021
regulation of intracellular transport GO:0032386 159 0.021
Mouse
muscle cell differentiation GO:0042692 261 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
cellular protein catabolic process GO:0044257 155 0.021
Mouse
muscle tissue development GO:0060537 308 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
lymphocyte proliferation GO:0046651 164 0.021
regulation of t cell activation GO:0050863 170 0.021
positive regulation of cell development GO:0010720 237 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.020
Mouse
divalent inorganic cation transport GO:0072511 178 0.020
Mouse Worm
apoptotic signaling pathway GO:0097190 306 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
meiotic nuclear division GO:0007126 115 0.020
protein maturation GO:0051604 176 0.020
sensory organ morphogenesis GO:0090596 242 0.020
blood circulation GO:0008015 195 0.020
stem cell differentiation GO:0048863 268 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
sequestering of calcium ion GO:0051208 18 0.020
Mouse
regulation of transmembrane transport GO:0034762 128 0.020
Mouse
chromatin organization GO:0006325 206 0.020
regulation of protein localization GO:0032880 231 0.020
Mouse
regulation of secretion GO:0051046 274 0.019
Mouse
multicellular organismal signaling GO:0035637 91 0.019
calcium ion transport GO:0006816 159 0.019
Mouse Worm
meiotic cell cycle process GO:1903046 77 0.019
cellular homeostasis GO:0019725 240 0.019
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.019
Mouse
regionalization GO:0003002 337 0.019
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.019
Mouse
striated muscle tissue development GO:0014706 293 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
Mouse
adaptive immune response GO:0002250 155 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
oxidation reduction process GO:0055114 342 0.019
dna repair GO:0006281 107 0.018
sequestering of metal ion GO:0051238 19 0.018
Mouse
regulation of establishment of protein localization GO:0070201 181 0.018
Mouse
cation homeostasis GO:0055080 212 0.018
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
organelle assembly GO:0070925 177 0.018
response to radiation GO:0009314 165 0.018
mitotic cell cycle process GO:1903047 159 0.018
Mouse
cellular ion homeostasis GO:0006873 165 0.018
Mouse
regulation of cell motility GO:2000145 236 0.018
cellular lipid metabolic process GO:0044255 323 0.018
fertilization GO:0009566 127 0.018
Mouse
glycosyl compound metabolic process GO:1901657 246 0.017
positive regulation of defense response GO:0031349 124 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
cell type specific apoptotic process GO:0097285 268 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
heterocycle catabolic process GO:0046700 280 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
Mouse
protein processing GO:0016485 163 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
covalent chromatin modification GO:0016569 163 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
Mouse
regulation of ion transport GO:0043269 215 0.017
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.017
Mouse
chromatin modification GO:0016568 187 0.017
urogenital system development GO:0001655 261 0.017
Mouse
protein localization to organelle GO:0033365 185 0.017
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.017
nuclear transport GO:0051169 139 0.017
Mouse
immune response activating signal transduction GO:0002757 116 0.017
glycoprotein metabolic process GO:0009100 116 0.017
anatomical structure homeostasis GO:0060249 145 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
establishment of protein localization to organelle GO:0072594 118 0.016
Mouse
sensory perception GO:0007600 245 0.016
Mouse
regulation of cell cycle process GO:0010564 160 0.016
Mouse
male meiosis GO:0007140 37 0.016
regulation of response to wounding GO:1903034 189 0.016
b cell activation GO:0042113 161 0.016
nitrogen compound transport GO:0071705 271 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
regulation of kinase activity GO:0043549 249 0.016
membrane organization GO:0061024 245 0.016
neuronal action potential GO:0019228 54 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
action potential GO:0001508 78 0.016
microtubule based process GO:0007017 236 0.016
Mouse
response to organonitrogen compound GO:0010243 246 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
Mouse
embryonic organ morphogenesis GO:0048562 276 0.016
meiotic cell cycle GO:0051321 122 0.016
transmission of nerve impulse GO:0019226 76 0.016
forebrain development GO:0030900 302 0.016
circulatory system process GO:0003013 197 0.016
ras protein signal transduction GO:0007265 77 0.016
aromatic compound catabolic process GO:0019439 286 0.016
regulation of cell migration GO:0030334 219 0.016
regulation of multi organism process GO:0043900 111 0.016
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
oocyte axis specification GO:0007309 2 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
response to organic cyclic compound GO:0014070 198 0.015
regulation of proteolysis GO:0030162 164 0.015
Mouse
camera type eye development GO:0043010 266 0.015
mapk cascade GO:0000165 281 0.015
gliogenesis GO:0042063 141 0.015
histone modification GO:0016570 159 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
muscle system process GO:0003012 141 0.015
dna recombination GO:0006310 92 0.015
renal system development GO:0072001 225 0.015
Mouse
rho protein signal transduction GO:0007266 32 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
regulation of secretion by cell GO:1903530 249 0.015
Mouse
methylation GO:0032259 134 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
skeletal muscle organ development GO:0060538 163 0.015
regulation of leukocyte mediated immunity GO:0002703 104 0.015
rhythmic process GO:0048511 174 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
neuron death GO:0070997 154 0.015
chromosome organization involved in meiosis GO:0070192 39 0.015
regulation of binding GO:0051098 111 0.015
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.015
synapsis GO:0007129 34 0.015
axonogenesis GO:0007409 274 0.015
actin cytoskeleton organization GO:0030036 220 0.015
cellular response to lipid GO:0071396 145 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
b cell differentiation GO:0030183 78 0.014
positive regulation of transferase activity GO:0051347 167 0.014
regulation of innate immune response GO:0045088 91 0.014
macromolecule methylation GO:0043414 120 0.014
metal ion homeostasis GO:0055065 189 0.014
Mouse
meiosis i GO:0007127 60 0.014
positive regulation of cell activation GO:0050867 158 0.014
regulation of anatomical structure size GO:0090066 178 0.014
blood vessel morphogenesis GO:0048514 285 0.014
leukocyte mediated immunity GO:0002443 174 0.014
intracellular mrna localization GO:0008298 4 0.014
dephosphorylation GO:0016311 129 0.014
regulation of inflammatory response GO:0050727 147 0.014
t cell differentiation GO:0030217 174 0.014
response to light stimulus GO:0009416 135 0.014
positive regulation of cytokine production GO:0001819 174 0.014
response to lipopolysaccharide GO:0032496 128 0.014
positive regulation of secretion GO:0051047 130 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
cell adhesion GO:0007155 329 0.013
Mouse
endomembrane system organization GO:0010256 147 0.013
fat cell differentiation GO:0045444 160 0.013
learning or memory GO:0007611 148 0.013
cognition GO:0050890 149 0.013
maintenance of location GO:0051235 89 0.013
Mouse
tissue homeostasis GO:0001894 115 0.013
negative regulation of immune effector process GO:0002698 55 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
negative regulation of cell development GO:0010721 169 0.013
myeloid cell homeostasis GO:0002262 114 0.013
skeletal system development GO:0001501 356 0.013
Mouse
muscle contraction GO:0006936 101 0.013
regulation of mapk cascade GO:0043408 248 0.013
stem cell development GO:0048864 219 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
glial cell differentiation GO:0010001 131 0.013
positive regulation of cell death GO:0010942 224 0.013
regulation of hydrolase activity GO:0051336 246 0.013
protein targeting GO:0006605 143 0.013
Mouse
sulfur compound metabolic process GO:0006790 100 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
Mouse
regulation of cellular component size GO:0032535 121 0.013
lateral inhibition GO:0046331 1 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
Mouse
thermosensory behavior GO:0040040 1 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
response to peptide GO:1901652 136 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
Mouse Worm
mitotic cell cycle GO:0000278 195 0.013
Mouse
extracellular structure organization GO:0043062 148 0.013
regulation of metal ion transport GO:0010959 106 0.013
Mouse
positive regulation of apoptotic process GO:0043065 217 0.013
angiogenesis GO:0001525 201 0.013
heart process GO:0003015 94 0.013
response to peptide hormone GO:0043434 127 0.013
cell activation involved in immune response GO:0002263 126 0.013
anion transport GO:0006820 177 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
translation GO:0006412 93 0.012
ossification GO:0001503 216 0.012
negative regulation of protein modification process GO:0031400 163 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
glycosylation GO:0070085 62 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
regulation of protein kinase activity GO:0045859 232 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
Mouse
oocyte construction GO:0007308 2 0.012
myelination GO:0042552 74 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
regulation of neuron projection development GO:0010975 169 0.012
developmental maturation GO:0021700 193 0.012
nucleoside metabolic process GO:0009116 246 0.012
positive regulation of innate immune response GO:0045089 80 0.012
regulation of homeostatic process GO:0032844 182 0.012
Mouse
heart morphogenesis GO:0003007 178 0.012
protein import GO:0017038 101 0.012
Mouse
defense response to other organism GO:0098542 197 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
locomotory behavior GO:0007626 195 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
protein localization to nucleus GO:0034504 121 0.012
Mouse
defense response to virus GO:0051607 68 0.012
positive regulation of immune effector process GO:0002699 107 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
multi multicellular organism process GO:0044706 109 0.012
Worm
regulation of cytoskeleton organization GO:0051493 122 0.012
Mouse
regulation of body fluid levels GO:0050878 162 0.012
cellular protein complex assembly GO:0043623 116 0.012
asymmetric stem cell division GO:0098722 3 0.012
single fertilization GO:0007338 82 0.012
Mouse
leukocyte proliferation GO:0070661 172 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
compound eye development GO:0048749 1 0.012
regulation of cellular response to stress GO:0080135 159 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
kidney development GO:0001822 213 0.011
Mouse
gonad development GO:0008406 141 0.011
positive regulation of organelle organization GO:0010638 128 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
Mouse
leukocyte migration GO:0050900 124 0.011
epithelial cell proliferation GO:0050673 174 0.011
positive regulation of cell motility GO:2000147 116 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
second messenger mediated signaling GO:0019932 73 0.011
regulation of adaptive immune response GO:0002819 90 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
nuclear import GO:0051170 95 0.011
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
Mouse
positive regulation of nervous system development GO:0051962 221 0.011
organophosphate catabolic process GO:0046434 232 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
negative regulation of response to wounding GO:1903035 77 0.011
regulation of protein catabolic process GO:0042176 108 0.011
Mouse
organic hydroxy compound transport GO:0015850 93 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
Mouse
ribonucleoside metabolic process GO:0009119 245 0.011
response to growth factor GO:0070848 198 0.011
gland development GO:0048732 330 0.011
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
Mouse
connective tissue development GO:0061448 179 0.011
Mouse
macromolecule glycosylation GO:0043413 55 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
wnt signaling pathway GO:0016055 188 0.011
regulation of muscle system process GO:0090257 80 0.011
extracellular matrix organization GO:0030198 147 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
Mouse
male genitalia morphogenesis GO:0048808 4 0.011
organic anion transport GO:0015711 137 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
regulation of translation GO:0006417 71 0.011
regulation of actin nucleation GO:0051125 4 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
negative regulation of cell activation GO:0050866 111 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
male anatomical structure morphogenesis GO:0090598 4 0.011
regulation of chromosome organization GO:0033044 83 0.011
positive regulation of t cell activation GO:0050870 101 0.011
activation of mapk activity involved in innate immune response GO:0035419 2 0.011
response to oxidative stress GO:0006979 123 0.011
heart contraction GO:0060047 93 0.011
ensheathment of neurons GO:0007272 76 0.011
rna processing GO:0006396 105 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
mitochondrion distribution GO:0048311 4 0.011
respiratory system development GO:0060541 190 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
positive regulation of viral genome replication GO:0045070 2 0.010
organelle localization GO:0051640 179 0.010
calcium ion homeostasis GO:0055074 127 0.010
Mouse
protein polymerization GO:0051258 57 0.010
endocytosis GO:0006897 168 0.010
bone development GO:0060348 120 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
synapse organization GO:0050808 125 0.010
skeletal system morphogenesis GO:0048705 203 0.010
Mouse
retina development in camera type eye GO:0060041 119 0.010
leukocyte chemotaxis GO:0030595 69 0.010
negative regulation of defense response GO:0031348 77 0.010
cell growth GO:0016049 130 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
regulation of neuron death GO:1901214 134 0.010
single organism nuclear import GO:1902593 95 0.010
Mouse
epithelial tube morphogenesis GO:0060562 303 0.010
Mouse
mitochondrion organization GO:0007005 134 0.010
multicellular organism growth GO:0035264 161 0.010
regulation of ossification GO:0030278 112 0.010
negative regulation of homeostatic process GO:0032845 71 0.010
Mouse
nucleotide catabolic process GO:0009166 217 0.010
cell fate commitment GO:0045165 210 0.010
nucleoside catabolic process GO:0009164 206 0.010

Pkd2l2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.019
immune system disease DOID:2914 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
central nervous system disease DOID:331 0 0.016
musculoskeletal system disease DOID:17 0 0.015
hematopoietic system disease DOID:74 0 0.015
sensory system disease DOID:0050155 0 0.012
cardiovascular system disease DOID:1287 0 0.011
inherited metabolic disorder DOID:655 0 0.010
neurodegenerative disease DOID:1289 0 0.010