Mus musculus

0 known processes

Rfwd3

ring finger and WD repeat domain 3

(Aliases: MGC27888,BC027246)

Rfwd3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.177
dna metabolic process GO:0006259 303 0.170
methylation GO:0032259 134 0.111
histone methylation GO:0016571 71 0.089
chromatin organization GO:0006325 206 0.081
cellular response to dna damage stimulus GO:0006974 207 0.079
Human
histone modification GO:0016570 159 0.079
mitotic cell cycle GO:0000278 195 0.071
Human
histone lysine methylation GO:0034968 50 0.060
covalent chromatin modification GO:0016569 163 0.060
organelle fission GO:0048285 170 0.059
inner cell mass cell proliferation GO:0001833 15 0.056
cellular amino acid metabolic process GO:0006520 103 0.054
macromolecule methylation GO:0043414 120 0.051
regulation of histone methylation GO:0031060 30 0.050
germ cell development GO:0007281 185 0.045
amine metabolic process GO:0009308 45 0.044
chromatin modification GO:0016568 187 0.043
small gtpase mediated signal transduction GO:0007264 97 0.042
lateral inhibition GO:0046331 1 0.041
dna dependent dna replication GO:0006261 24 0.040
lymphocyte mediated immunity GO:0002449 139 0.040
rna processing GO:0006396 105 0.036
mrna metabolic process GO:0016071 84 0.036
ribonucleotide metabolic process GO:0009259 291 0.035
dna conformation change GO:0071103 37 0.034
dna replication GO:0006260 52 0.034
response to radiation GO:0009314 165 0.033
Human
double strand break repair GO:0006302 48 0.033
regulation of organelle organization GO:0033043 289 0.033
response to oxidative stress GO:0006979 123 0.032
dna recombination GO:0006310 92 0.032
macromolecule catabolic process GO:0009057 281 0.032
somatic cell dna recombination GO:0016444 51 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
endocytosis GO:0006897 168 0.032
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.031
protein methylation GO:0006479 81 0.031
apoptotic signaling pathway GO:0097190 306 0.031
cell cycle g1 s phase transition GO:0044843 57 0.031
Human
aromatic compound catabolic process GO:0019439 286 0.031
purine containing compound metabolic process GO:0072521 311 0.031
meiotic cell cycle GO:0051321 122 0.030
somatic diversification of immune receptors GO:0002200 53 0.030
mitotic cell cycle process GO:1903047 159 0.030
Human
production of molecular mediator of immune response GO:0002440 103 0.029
leukocyte activation involved in immune response GO:0002366 126 0.029
nucleoside metabolic process GO:0009116 246 0.029
cellular ketone metabolic process GO:0042180 84 0.029
positive regulation of protein modification process GO:0031401 299 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
response to inorganic substance GO:0010035 96 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
heterocycle catabolic process GO:0046700 280 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
response to lipopolysaccharide GO:0032496 128 0.027
rna splicing via transesterification reactions GO:0000375 43 0.026
regulation of histone h3 k4 methylation GO:0051569 12 0.026
ras protein signal transduction GO:0007265 77 0.026
homeostasis of number of cells GO:0048872 210 0.026
base excision repair GO:0006284 9 0.025
cell type specific apoptotic process GO:0097285 268 0.025
somatic diversification of immunoglobulins GO:0016445 43 0.025
regulation of chromatin modification GO:1903308 57 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
intracellular protein transport GO:0006886 204 0.024
immune effector process GO:0002252 321 0.024
oxidation reduction process GO:0055114 342 0.024
b cell activation GO:0042113 161 0.024
immunoglobulin production GO:0002377 73 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
lymphocyte activation involved in immune response GO:0002285 93 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
protein alkylation GO:0008213 81 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
cell activation involved in immune response GO:0002263 126 0.022
regulation of intracellular transport GO:0032386 159 0.022
cellular amine metabolic process GO:0044106 44 0.022
gene silencing by rna GO:0031047 19 0.022
positive regulation of programmed cell death GO:0043068 218 0.021
histone h3 k4 methylation GO:0051568 23 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.021
leukocyte mediated immunity GO:0002443 174 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
myeloid cell differentiation GO:0030099 233 0.021
purine nucleoside metabolic process GO:0042278 241 0.020
response to growth factor GO:0070848 198 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
membrane organization GO:0061024 245 0.020
pancreas development GO:0031016 57 0.020
immunoglobulin mediated immune response GO:0016064 69 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
response to light stimulus GO:0009416 135 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
cell fate commitment GO:0045165 210 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
response to organonitrogen compound GO:0010243 246 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
mrna processing GO:0006397 63 0.018
b cell activation involved in immune response GO:0002312 50 0.018
nitrogen compound transport GO:0071705 271 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
regulation of cell cycle process GO:0010564 160 0.018
Human
regulation of dna methylation GO:0044030 12 0.017
regulation of cellular response to stress GO:0080135 159 0.017
Human
adaptive immune response GO:0002250 155 0.017
dna modification GO:0006304 50 0.017
regulation of transcription by chromatin organization GO:0034401 0 0.017
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.017
mrna splicing via spliceosome GO:0000398 43 0.017
response to testosterone GO:0033574 3 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
protein ubiquitination GO:0016567 171 0.017
Human
purine containing compound catabolic process GO:0072523 213 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
response to uv GO:0009411 44 0.016
positive regulation of intracellular transport GO:0032388 70 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
rna catabolic process GO:0006401 29 0.016
meiotic nuclear division GO:0007126 115 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
b cell mediated immunity GO:0019724 71 0.015
negative regulation of molecular function GO:0044092 258 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
isotype switching GO:0045190 36 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
regulation of histone h3 k36 methylation GO:0000414 1 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
regulation of hydrolase activity GO:0051336 246 0.015
camera type eye development GO:0043010 266 0.015
cell adhesion GO:0007155 329 0.015
negative regulation of histone h3 k9 methylation GO:0051573 4 0.015
blastocyst growth GO:0001832 23 0.015
positive regulation of cell death GO:0010942 224 0.015
negative regulation of protein modification process GO:0031400 163 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of intracellular protein transport GO:0033157 82 0.015
nuclear dna replication GO:0033260 3 0.015
regulation of neuron death GO:1901214 134 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
rna interference GO:0016246 2 0.014
recombinational repair GO:0000725 21 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
protein targeting GO:0006605 143 0.014
peptidyl amino acid modification GO:0018193 336 0.014
rna 3 end processing GO:0031123 20 0.014
angiogenesis GO:0001525 201 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
dna replication independent nucleosome assembly GO:0006336 1 0.014
regulation of membrane potential GO:0042391 192 0.014
dna methylation GO:0006306 43 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
Human
negative regulation of protein metabolic process GO:0051248 282 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
blood vessel morphogenesis GO:0048514 285 0.013
cellular response to lipid GO:0071396 145 0.013
multicellular organismal signaling GO:0035637 91 0.013
action potential GO:0001508 78 0.013
chemotaxis GO:0006935 247 0.013
development of primary sexual characteristics GO:0045137 143 0.013
sensory organ morphogenesis GO:0090596 242 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.013
neuron death GO:0070997 154 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
response to acid chemical GO:0001101 111 0.013
positive regulation of chromatin modification GO:1903310 28 0.013
skeletal system development GO:0001501 356 0.013
lipid biosynthetic process GO:0008610 179 0.013
protein dna complex subunit organization GO:0071824 28 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
response to vitamin a GO:0033189 1 0.013
positive regulation of immune effector process GO:0002699 107 0.013
regulation of chromatin organization GO:1902275 57 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
protein localization to organelle GO:0033365 185 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
axonogenesis GO:0007409 274 0.013
carbohydrate homeostasis GO:0033500 128 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
ncrna 3 end processing GO:0043628 2 0.012
response to extracellular stimulus GO:0009991 127 0.012
response to organic cyclic compound GO:0014070 198 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
Human
nuclear division GO:0000280 158 0.012
skin development GO:0043588 220 0.012
regulation of cell cycle GO:0051726 281 0.012
Human
positive regulation of organelle organization GO:0010638 128 0.012
digestive system development GO:0055123 200 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
regulation of histone modification GO:0031056 56 0.012
regulation of cell activation GO:0050865 289 0.012
cellular response to inorganic substance GO:0071241 37 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
nucleotide metabolic process GO:0009117 332 0.012
double strand break repair via nonhomologous end joining GO:0006303 10 0.012
body morphogenesis GO:0010171 45 0.012
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.012
circadian rhythm GO:0007623 114 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
dna hypermethylation GO:0044026 3 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
cytoplasmic transport GO:0016482 234 0.011
cofactor metabolic process GO:0051186 80 0.011
neuron apoptotic process GO:0051402 142 0.011
response to transforming growth factor beta GO:0071559 88 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
regulation of hormone levels GO:0010817 211 0.011
positive regulation of histone h3 k4 methylation GO:0051571 5 0.011
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.011
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
organophosphate catabolic process GO:0046434 232 0.011
transmission of nerve impulse GO:0019226 76 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
gland development GO:0048732 330 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
cellular protein complex assembly GO:0043623 116 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
dna alkylation GO:0006305 43 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
stem cell development GO:0048864 219 0.010
dna templated transcription termination GO:0006353 4 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
mitotic sister chromatid segregation GO:0000070 14 0.010
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.010
cytokine production GO:0001816 319 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
response to reactive oxygen species GO:0000302 56 0.010
anatomical structure homeostasis GO:0060249 145 0.010
rna splicing GO:0008380 54 0.010
regulation of protein targeting GO:1903533 61 0.010

Rfwd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.054
organ system cancer DOID:0050686 0 0.052
cancer DOID:162 0 0.052
nervous system disease DOID:863 0 0.037
disease of anatomical entity DOID:7 0 0.037
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.013
neuropathy DOID:870 0 0.013
peripheral neuropathy DOID:0060053 0 0.012
neurodegenerative disease DOID:1289 0 0.011
central nervous system disease DOID:331 0 0.011