Mus musculus

273 known processes

Mesp1

mesoderm posterior 1

(Aliases: MGC159208,MGC159210,bHLHc5)

Mesp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart morphogenesis GO:0003007 178 0.999
positive regulation of transcription via serum response element binding GO:0010735 1 0.996
cell migration to the midline involved in heart development GO:0003318 1 0.996
cardiac chamber morphogenesis GO:0003206 93 0.992
clara cell differentiation GO:0060486 4 0.992
atrial cardiac muscle cell differentiation GO:0055011 2 0.988
embryonic organ morphogenesis GO:0048562 276 0.986
positive regulation of cardioblast differentiation GO:0051891 3 0.982
cardiac cell fate determination GO:0060913 2 0.978
embryonic heart tube left right pattern formation GO:0060971 5 0.972
ventricular cardiac myofibril assembly GO:0055005 3 0.970
purkinje myocyte differentiation GO:0003168 1 0.961
circulatory system process GO:0003013 197 0.957
cardiac pacemaker cell fate commitment GO:0060927 1 0.956
embryonic heart tube development GO:0035050 65 0.955
cardiac muscle tissue development GO:0048738 130 0.948
Human
muscle tissue development GO:0060537 308 0.947
Human
striated muscle tissue development GO:0014706 293 0.941
Human
cardiac muscle cell differentiation GO:0055007 69 0.939
Human
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.932
atrial cardiac muscle cell development GO:0055014 2 0.932
ventral spinal cord interneuron fate determination GO:0060580 1 0.926
cardiocyte differentiation GO:0035051 87 0.924
pancreatic pp cell fate commitment GO:0003329 2 0.920
atrioventricular node cell development GO:0060928 2 0.916
regionalization GO:0003002 337 0.914
cardiac septum development GO:0003279 59 0.914
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.905
atrioventricular node cell differentiation GO:0060922 2 0.905
nephric duct formation GO:0072179 4 0.902
lung development GO:0030324 164 0.878
regulation of cardioblast differentiation GO:0051890 3 0.877
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.876
cell adhesion GO:0007155 329 0.874
Fly
cardioblast migration GO:0003260 1 0.872
regulation of secretion GO:0051046 274 0.869
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.857
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.840
muscle system process GO:0003012 141 0.840
epithelial tube morphogenesis GO:0060562 303 0.836
septum primum development GO:0003284 4 0.830
atrioventricular node development GO:0003162 3 0.822
blood circulation GO:0008015 195 0.821
cardiac chamber development GO:0003205 108 0.810
somitogenesis GO:0001756 69 0.804
Zebrafish Mouse
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.802
determination of heart left right asymmetry GO:0061371 48 0.794
atrial septum primum morphogenesis GO:0003289 3 0.788
heart process GO:0003015 94 0.787
oligodendrocyte cell fate commitment GO:0021779 5 0.779
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.776
cardiac septum morphogenesis GO:0060411 46 0.772
pyramidal neuron migration GO:0021852 1 0.762
atrioventricular node cell fate commitment GO:0060929 1 0.749
growth plate cartilage chondrocyte growth GO:0003430 2 0.745
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.742
heart contraction GO:0060047 93 0.734
type b pancreatic cell fate commitment GO:0003327 1 0.716
atrioventricular valve morphogenesis GO:0003181 13 0.710
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.708
regulation of cellular ketone metabolic process GO:0010565 66 0.707
bundle of his development GO:0003166 4 0.702
telencephalon development GO:0021537 186 0.699
subpallium neuron fate commitment GO:0060163 2 0.694
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.693
proepicardium development GO:0003342 2 0.685
pancreatic pp cell differentiation GO:0003312 2 0.661
cardiac muscle tissue morphogenesis GO:0055008 44 0.658
pituitary gland development GO:0021983 38 0.652
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.651
stem cell differentiation GO:0048863 268 0.642
ventricular septum morphogenesis GO:0060412 27 0.641
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.627
specification of organ identity GO:0010092 30 0.624
neural tube closure GO:0001843 90 0.620
blood vessel morphogenesis GO:0048514 285 0.620
determination of left right symmetry GO:0007368 80 0.618
glandular epithelial cell differentiation GO:0002067 38 0.609
globus pallidus development GO:0021759 2 0.603
mitral valve development GO:0003174 4 0.603
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.602
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.597
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.597
appendage morphogenesis GO:0035107 149 0.593
Fly
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.593
regulation of blood circulation GO:1903522 93 0.580
hypophysis morphogenesis GO:0048850 3 0.572
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.569
lung cell differentiation GO:0060479 30 0.566
auditory receptor cell fate determination GO:0042668 3 0.565
outflow tract morphogenesis GO:0003151 53 0.562
limbic system development GO:0021761 72 0.560
menarche GO:0042696 1 0.555
heart trabecula formation GO:0060347 14 0.555
lung induction GO:0060492 3 0.553
forebrain development GO:0030900 302 0.551
embryonic heart tube formation GO:0003144 1 0.549
cardiac conduction system development GO:0003161 12 0.547
Human
forebrain morphogenesis GO:0048853 17 0.546
mesenchyme development GO:0060485 152 0.544
cardiac ventricle formation GO:0003211 8 0.538
Human
endocrine system development GO:0035270 98 0.536
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.533
positive regulation of transcription by glucose GO:0046016 3 0.533
ventricular cardiac muscle cell differentiation GO:0055012 17 0.528
male gamete generation GO:0048232 285 0.527
cytoplasmic transport GO:0016482 234 0.523
mitral valve morphogenesis GO:0003183 4 0.522
smoothened signaling pathway GO:0007224 105 0.519
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.519
regulation of organ morphogenesis GO:2000027 144 0.517
mesenchymal cell development GO:0014031 93 0.515
pancreatic a cell fate commitment GO:0003326 2 0.512
skeletal muscle cell differentiation GO:0035914 66 0.509
neuron projection guidance GO:0097485 141 0.504
embryonic skeletal system morphogenesis GO:0048704 91 0.502
hindbrain development GO:0030902 128 0.500
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.496
forebrain neuron differentiation GO:0021879 52 0.494
lung epithelial cell differentiation GO:0060487 29 0.493
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.492
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.488
stem cell development GO:0048864 219 0.487
forebrain neuron fate commitment GO:0021877 13 0.486
positive regulation of interleukin 13 production GO:0032736 4 0.481
cellular calcium ion homeostasis GO:0006874 119 0.470
regulation of auditory receptor cell differentiation GO:0045607 4 0.468
cellular ketone metabolic process GO:0042180 84 0.467
limb development GO:0060173 166 0.456
trachea formation GO:0060440 3 0.453
neural crest cell development GO:0014032 48 0.450
left right pattern formation GO:0060972 23 0.448
aortic valve morphogenesis GO:0003180 4 0.446
closure of optic fissure GO:0061386 2 0.443
ventral spinal cord interneuron fate commitment GO:0060579 14 0.439
regulation of blood pressure GO:0008217 93 0.439
metanephric capsule specification GO:0072267 1 0.435
mesenchymal cell differentiation GO:0048762 107 0.433
response to vitamin a GO:0033189 1 0.429
positive regulation of ureteric bud formation GO:0072107 3 0.423
limb morphogenesis GO:0035108 149 0.422
endocardial cell differentiation GO:0060956 4 0.421
chromatin organization GO:0006325 206 0.421
regulation of cardiac muscle tissue development GO:0055024 31 0.421
respiratory system development GO:0060541 190 0.416
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.414
regulation of heart contraction GO:0008016 77 0.413
pulmonary myocardium development GO:0003350 3 0.410
embryonic viscerocranium morphogenesis GO:0048703 8 0.406
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.401
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.399
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.396
determination of digestive tract left right asymmetry GO:0071907 1 0.393
epithelial cell fate commitment GO:0072148 13 0.391
embryonic placenta development GO:0001892 98 0.389
positive regulation of protein phosphorylation GO:0001934 242 0.388
neuron fate specification GO:0048665 30 0.387
cardiac ventricle development GO:0003231 83 0.387
Human
pancreas development GO:0031016 57 0.386
heart field specification GO:0003128 6 0.385
regulation of ureteric bud formation GO:0072106 3 0.379
amine metabolic process GO:0009308 45 0.376
development of primary sexual characteristics GO:0045137 143 0.367
gland development GO:0048732 330 0.366
carbohydrate metabolic process GO:0005975 230 0.365
granulocyte differentiation GO:0030851 17 0.364
hypothalamus development GO:0021854 16 0.360
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.360
prostate gland stromal morphogenesis GO:0060741 2 0.358
placenta development GO:0001890 140 0.350
regulation of binding GO:0051098 111 0.349
somatotropin secreting cell differentiation GO:0060126 4 0.347
pallium development GO:0021543 120 0.346
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.344
diencephalon development GO:0021536 63 0.343
lung epithelium development GO:0060428 37 0.341
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 0.340
morphogenesis of embryonic epithelium GO:0016331 159 0.338
digestive tract development GO:0048565 190 0.334
ear morphogenesis GO:0042471 118 0.333
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.327
cartilage development GO:0051216 140 0.325
hematopoietic progenitor cell differentiation GO:0002244 143 0.322
forebrain generation of neurons GO:0021872 63 0.322
muscle tissue morphogenesis GO:0060415 53 0.320
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000703 1 0.320
epithelial cell development GO:0002064 159 0.320
cell type specific apoptotic process GO:0097285 268 0.319
digestive system development GO:0055123 200 0.317
gabaergic neuron differentiation GO:0097154 11 0.317
negative regulation of neuron differentiation GO:0045665 101 0.314
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.312
cardioblast differentiation GO:0010002 13 0.312
heart trabecula morphogenesis GO:0061384 26 0.312
auditory receptor cell fate specification GO:0042667 1 0.311
muscle cell differentiation GO:0042692 261 0.310
olfactory lobe development GO:0021988 32 0.310
tube formation GO:0035148 140 0.309
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.303
embryonic heart tube morphogenesis GO:0003143 51 0.303
his purkinje system cell differentiation GO:0060932 2 0.302
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.302
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.297
gonad development GO:0008406 141 0.295
skeletal system morphogenesis GO:0048705 203 0.295
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.291
paraxial mesodermal cell differentiation GO:0048342 2 0.287
embryonic skeletal system development GO:0048706 120 0.281
renal capsule specification GO:0072130 1 0.281
regulation of system process GO:0044057 200 0.281
cardiac atrium development GO:0003230 24 0.280
Human
astrocyte fate commitment GO:0060018 4 0.280
dorsal ventral axon guidance GO:0033563 3 0.279
circadian rhythm GO:0007623 114 0.276
epithelial tube formation GO:0072175 130 0.276
septum transversum development GO:0003343 2 0.275
cardiac myofibril assembly GO:0055003 12 0.275
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.273
muscle cell proliferation GO:0033002 52 0.272
cell migration involved in heart formation GO:0060974 1 0.271
epidermis development GO:0008544 187 0.271
germ cell development GO:0007281 185 0.271
oligodendrocyte differentiation GO:0048709 53 0.269
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.269
myeloid cell differentiation GO:0030099 233 0.264
locus ceruleus development GO:0021703 1 0.264
chondrocyte hypertrophy GO:0003415 4 0.264
gastrulation GO:0007369 116 0.263
labyrinthine layer blood vessel development GO:0060716 21 0.261
fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000699 1 0.260
renal capsule formation GO:0072129 1 0.257
terpenoid metabolic process GO:0006721 25 0.257
ureteric bud morphogenesis GO:0060675 62 0.255
cardiac ventricle morphogenesis GO:0003208 50 0.252
Human
regulation of cardiac cell fate specification GO:2000043 1 0.250
endothelial cell fate commitment GO:0060839 2 0.248
negative regulation of endodermal cell fate specification GO:0042664 1 0.246
paraxial mesodermal cell fate commitment GO:0048343 2 0.246
ventricular cardiac muscle tissue development GO:0003229 38 0.245
embryonic epithelial tube formation GO:0001838 130 0.244
regulation of homeostatic process GO:0032844 182 0.243
negative regulation of glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000734 1 0.243
vascular process in circulatory system GO:0003018 62 0.241
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.238
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.235
cardiac endothelial cell differentiation GO:0003348 4 0.232
cell fate determination involved in pattern specification GO:0060582 1 0.230
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.228
cerebral cortex neuron differentiation GO:0021895 19 0.225
his purkinje system development GO:0003164 4 0.224
ventricular septum development GO:0003281 42 0.223
endocrine pancreas development GO:0031018 29 0.222
sensory organ morphogenesis GO:0090596 242 0.221
lung lobe formation GO:0060464 1 0.220
cardiac epithelial to mesenchymal transition GO:0060317 18 0.219
central nervous system morphogenesis GO:0021551 2 0.216
organic hydroxy compound metabolic process GO:1901615 203 0.216
camera type eye development GO:0043010 266 0.215
midbrain hindbrain boundary maturation GO:0021732 1 0.215
heart valve morphogenesis GO:0003179 21 0.213
labyrinthine layer development GO:0060711 49 0.213
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.212
bmp signaling pathway GO:0030509 93 0.212
regulation of cardiac muscle tissue growth GO:0055021 26 0.212
intracellular receptor signaling pathway GO:0030522 74 0.211
regulation of muscle tissue development GO:1901861 97 0.211
spinal cord development GO:0021510 81 0.210
atrial septum morphogenesis GO:0060413 11 0.206
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.206
renal vesicle development GO:0072087 17 0.204
leukocyte activation involved in immune response GO:0002366 126 0.204
epithelial cell proliferation GO:0050673 174 0.203
hormone secretion GO:0046879 128 0.201
positive regulation of odontogenesis GO:0042482 4 0.200
female sex differentiation GO:0046660 84 0.199
cell proliferation in hindbrain GO:0021534 10 0.199
neural crest cell differentiation GO:0014033 54 0.198
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.198
columnar cuboidal epithelial cell development GO:0002066 29 0.195
glial cell fate specification GO:0021780 5 0.195
nephron tubule morphogenesis GO:0072078 68 0.195
regulation of t cell activation GO:0050863 170 0.194
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.193
cerebellum formation GO:0021588 1 0.193
atrial ventricular junction remodeling GO:0003294 2 0.193
atrial septum development GO:0003283 12 0.193
vascular smooth muscle cell differentiation GO:0035886 11 0.191
Human
ureter maturation GO:0035799 4 0.190
primary prostatic bud elongation GO:0060516 2 0.190
stem cell maintenance GO:0019827 130 0.190
cardiac right ventricle formation GO:0003219 3 0.189
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.189
maintenance of location GO:0051235 89 0.188
corticotropin hormone secreting cell differentiation GO:0060128 3 0.187
regulation of blood vessel size GO:0050880 56 0.187
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.187
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.186
secondary heart field specification GO:0003139 6 0.186
carbohydrate derivative biosynthetic process GO:1901137 183 0.185
metanephric renal vesicle morphogenesis GO:0072283 12 0.184
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.184
regulation of cellular amino acid metabolic process GO:0006521 5 0.183
spleen development GO:0048536 39 0.183
regulation of neuron projection development GO:0010975 169 0.182
negative regulation of striated muscle cell apoptotic process GO:0010664 8 0.182
skeletal muscle organ development GO:0060538 163 0.181
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.180
harderian gland development GO:0070384 2 0.180
homeostasis of number of cells GO:0048872 210 0.179
subpallium development GO:0021544 20 0.178
endodermal cell fate commitment GO:0001711 12 0.177
striated muscle cell proliferation GO:0014855 39 0.176
regulation of heart growth GO:0060420 31 0.175
cellular amine metabolic process GO:0044106 44 0.174
regulation of cytokine production GO:0001817 266 0.173
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.172
enteroendocrine cell differentiation GO:0035883 16 0.171
forebrain dorsal ventral pattern formation GO:0021798 6 0.170
response to steroid hormone GO:0048545 56 0.170
male gonad development GO:0008584 88 0.169
mesonephric duct morphogenesis GO:0072180 4 0.168
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.168
appendage development GO:0048736 166 0.168
Fly
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.168
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.166
regulation of glial cell differentiation GO:0045685 41 0.166
regulation of mesodermal cell fate specification GO:0042661 5 0.165
male sex differentiation GO:0046661 109 0.165
negative regulation of epithelial cell proliferation GO:0050680 64 0.164
positive regulation of mapk cascade GO:0043410 170 0.163
lung secretory cell differentiation GO:0061140 13 0.161
chromatin modification GO:0016568 187 0.161
outflow tract septum morphogenesis GO:0003148 11 0.161
cellular chemical homeostasis GO:0055082 215 0.160
negative regulation of mesodermal cell fate specification GO:0042662 3 0.158
retinal ganglion cell axon guidance GO:0031290 18 0.158
fused antrum stage GO:0048165 1 0.158
horizontal cell localization GO:0035852 1 0.156
nephron epithelium morphogenesis GO:0072088 68 0.156
mesonephric tubule formation GO:0072172 11 0.154
organic hydroxy compound biosynthetic process GO:1901617 77 0.153
sequestering of metal ion GO:0051238 19 0.153
formation of primary germ layer GO:0001704 77 0.153
positive regulation of programmed cell death GO:0043068 218 0.152
renal vesicle induction GO:0072034 3 0.152
female mating behavior GO:0060180 8 0.151
peptide secretion GO:0002790 114 0.151
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.151
plasma cell differentiation GO:0002317 3 0.149
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.149
histone acetylation GO:0016573 41 0.148
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.148
axon guidance GO:0007411 141 0.148
regulation of bmp signaling pathway GO:0030510 60 0.148
alpha beta t cell differentiation GO:0046632 69 0.147
myelination GO:0042552 74 0.147
regulation of mapk cascade GO:0043408 248 0.147
embryonic appendage morphogenesis GO:0035113 126 0.146
muscle contraction GO:0006936 101 0.145
regulation of nucleotide metabolic process GO:0006140 169 0.144
regulation of ossification GO:0030278 112 0.144
spermatogenesis GO:0007283 284 0.144
mesonephric duct formation GO:0072181 2 0.143
peptide metabolic process GO:0006518 46 0.143
renal tubule morphogenesis GO:0061333 72 0.142
sertoli cell differentiation GO:0060008 18 0.142
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.141
erythrocyte differentiation GO:0030218 88 0.138
regulation of vascular wound healing GO:0061043 2 0.137
positive regulation of sodium ion transport GO:0010765 13 0.137
organ maturation GO:0048799 17 0.137
rhombomere 3 morphogenesis GO:0021658 2 0.136
cardiac muscle cell development GO:0055013 39 0.136
prostate gland morphogenesis GO:0060512 32 0.136
respiratory tube development GO:0030323 167 0.136
cell cell signaling involved in kidney development GO:0060995 2 0.136
negative regulation of cell proliferation GO:0008285 296 0.135
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.134
growth plate cartilage chondrocyte development GO:0003431 3 0.133
regulation of erk1 and erk2 cascade GO:0070372 71 0.132
astrocyte differentiation GO:0048708 43 0.131
transcriptional activation by promoter enhancer looping GO:0071733 2 0.131
regulation of forebrain neuron differentiation GO:2000977 2 0.131
hypothalamus cell migration GO:0021855 5 0.129
negative regulation of gastrulation GO:2000542 3 0.129
lateral motor column neuron migration GO:0097477 3 0.129
metanephric nephron tubule formation GO:0072289 4 0.128
positive regulation of cardiac muscle tissue development GO:0055025 19 0.128
mesonephric tubule morphogenesis GO:0072171 63 0.128
pancreas morphogenesis GO:0061113 3 0.127
nephron tubule formation GO:0072079 20 0.127
histone modification GO:0016570 159 0.126
peptidyl amino acid modification GO:0018193 336 0.126
positive regulation of dna templated transcription initiation GO:2000144 5 0.126
lung proximal distal axis specification GO:0061115 1 0.125
regulation of antimicrobial humoral response GO:0002759 3 0.125
regulation of intracellular transport GO:0032386 159 0.124
skin development GO:0043588 220 0.123
tissue remodeling GO:0048771 102 0.123
prechordal plate formation GO:0021501 1 0.121
hair cell differentiation GO:0035315 40 0.120
cardiac pacemaker cell development GO:0060926 5 0.120
cardiac muscle contraction GO:0060048 32 0.120
ensheathment of neurons GO:0007272 76 0.119
negative regulation of protein metabolic process GO:0051248 282 0.119
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.119
kidney morphogenesis GO:0060993 83 0.118
cardiac atrium morphogenesis GO:0003209 23 0.117
Human
oligodendrocyte cell fate specification GO:0021778 5 0.117
posttranscriptional regulation of gene expression GO:0010608 155 0.117
cellular lipid metabolic process GO:0044255 323 0.117
neuron fate determination GO:0048664 9 0.116
neuron migration GO:0001764 122 0.116
regulation of ion transport GO:0043269 215 0.115
endocardial cushion formation GO:0003272 13 0.115
telencephalon regionalization GO:0021978 14 0.115
nephron morphogenesis GO:0072028 69 0.114
carboxylic acid biosynthetic process GO:0046394 86 0.114
catecholamine biosynthetic process GO:0042423 11 0.114
semicircular canal formation GO:0060876 1 0.114
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.113
renal capsule morphogenesis GO:0072128 1 0.113
response to growth factor GO:0070848 198 0.113
regulation of neuron differentiation GO:0045664 281 0.112
forebrain regionalization GO:0021871 25 0.112
spinal cord dorsal ventral patterning GO:0021513 23 0.112
nucleus accumbens development GO:0021768 1 0.112
neural tube patterning GO:0021532 43 0.112
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.111
midgut development GO:0007494 4 0.111
segmentation GO:0035282 93 0.111
Zebrafish Mouse
regulation of secretion by cell GO:1903530 249 0.109
mesangial cell differentiation GO:0072007 4 0.109
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.109
negative regulation of phosphate metabolic process GO:0045936 184 0.108
branching involved in ureteric bud morphogenesis GO:0001658 56 0.107
lateral mesodermal cell differentiation GO:0048371 3 0.106
cardiac cell development GO:0055006 41 0.104
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.104
rhombomere 5 development GO:0021571 4 0.103
cardiac cell fate commitment GO:0060911 10 0.103
embryonic limb morphogenesis GO:0030326 126 0.103
venous blood vessel development GO:0060841 13 0.102
hindbrain formation GO:0021576 1 0.102
endocardial cushion morphogenesis GO:0003203 18 0.102
peptide hormone secretion GO:0030072 109 0.101
response to inorganic substance GO:0010035 96 0.101
organonitrogen compound biosynthetic process GO:1901566 192 0.101
cellular metal ion homeostasis GO:0006875 151 0.101
specification of organ position GO:0010159 3 0.101
regulation of osteoblast differentiation GO:0045667 67 0.100
response to organic cyclic compound GO:0014070 198 0.100
wnt signaling pathway involved in kidney development GO:0061289 2 0.098
cellular response to lipid GO:0071396 145 0.098
carbon catabolite regulation of transcription GO:0045990 4 0.098
cardiac muscle cell proliferation GO:0060038 31 0.098
ureteric bud formation GO:0060676 7 0.098
ossification GO:0001503 216 0.097
tube closure GO:0060606 91 0.097
response to drug GO:0042493 75 0.097
lateral mesoderm morphogenesis GO:0048369 3 0.096
purine ribonucleotide metabolic process GO:0009150 290 0.096
lipid homeostasis GO:0055088 63 0.096
neural tube formation GO:0001841 108 0.095
ureteric bud development GO:0001657 94 0.095
regulation of endodermal cell differentiation GO:1903224 2 0.095
myotube differentiation GO:0014902 105 0.094
positive regulation of homeostatic process GO:0032846 64 0.094
methylation GO:0032259 134 0.093
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.093
response to retinoic acid GO:0032526 56 0.093
Zebrafish
regulation of stem cell proliferation GO:0072091 78 0.093
regulation of response to wounding GO:1903034 189 0.093
forebrain anterior posterior pattern specification GO:0021797 5 0.093
branching morphogenesis of an epithelial tube GO:0048754 159 0.093
dichotomous subdivision of terminal units involved in ureteric bud branching GO:0060678 1 0.092
carbohydrate homeostasis GO:0033500 128 0.092
liver development GO:0001889 66 0.092
catecholamine metabolic process GO:0006584 30 0.092
diterpenoid metabolic process GO:0016101 24 0.091
cardiac left ventricle morphogenesis GO:0003214 9 0.091
regulation of cellular amine metabolic process GO:0033238 20 0.091
glycoprotein metabolic process GO:0009100 116 0.091
negative regulation of phosphorus metabolic process GO:0010563 184 0.091
regulation of endodermal cell fate specification GO:0042663 2 0.091
myeloid leukocyte differentiation GO:0002573 119 0.091
sensory perception GO:0007600 245 0.090
pattern specification involved in metanephros development GO:0072268 4 0.090
regulation of myeloid leukocyte differentiation GO:0002761 58 0.090
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.090
cd4 positive alpha beta t cell activation GO:0035710 45 0.090
otic placode formation GO:0043049 1 0.090
mesoderm development GO:0007498 100 0.090

Mesp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.520
disease of anatomical entity DOID:7 0 0.520
cardiovascular system disease DOID:1287 0 0.520
congenital heart disease DOID:1682 0 0.429
heart septal defect DOID:1681 0 0.429
ventricular septal defect DOID:1657 0 0.429