Mus musculus

0 known processes

Fam53a

family with sequence similarity 53, member A

(Aliases: KIAA4017,Dntnp,2410018C17Rik,5430419M09Rik)

Fam53a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.198
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.076
cellular amino acid metabolic process GO:0006520 103 0.064
response to molecule of bacterial origin GO:0002237 143 0.063
spermatogenesis GO:0007283 284 0.063
regulation of protein kinase activity GO:0045859 232 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.062
protein modification by small protein conjugation or removal GO:0070647 207 0.058
regulation of kinase activity GO:0043549 249 0.053
regulation of defense response GO:0031347 233 0.051
male gamete generation GO:0048232 285 0.051
cellular amine metabolic process GO:0044106 44 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
amine metabolic process GO:0009308 45 0.046
striated muscle tissue development GO:0014706 293 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
negative regulation of intracellular signal transduction GO:1902532 167 0.043
peptidyl amino acid modification GO:0018193 336 0.042
protein catabolic process GO:0030163 221 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
regionalization GO:0003002 337 0.040
cardiac chamber morphogenesis GO:0003206 93 0.040
nitrogen compound transport GO:0071705 271 0.039
protein modification by small protein conjugation GO:0032446 187 0.039
positive regulation of apoptotic process GO:0043065 217 0.038
protein ubiquitination GO:0016567 171 0.038
regulation of cytokine production GO:0001817 266 0.037
microtubule based process GO:0007017 236 0.037
response to organonitrogen compound GO:0010243 246 0.036
cellular lipid metabolic process GO:0044255 323 0.035
negative regulation of molecular function GO:0044092 258 0.035
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
cytokine production GO:0001816 319 0.034
telencephalon development GO:0021537 186 0.034
response to lipopolysaccharide GO:0032496 128 0.033
urogenital system development GO:0001655 261 0.033
regulation of protein serine threonine kinase activity GO:0071900 157 0.033
regulation of cell cycle GO:0051726 281 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
homeostasis of number of cells GO:0048872 210 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.032
positive regulation of cell death GO:0010942 224 0.031
multi multicellular organism process GO:0044706 109 0.031
mapk cascade GO:0000165 281 0.031
amide transport GO:0042886 138 0.031
cellular protein catabolic process GO:0044257 155 0.031
gastrulation GO:0007369 116 0.031
gland development GO:0048732 330 0.031
negative regulation of immune system process GO:0002683 209 0.030
digestive system development GO:0055123 200 0.030
cellular response to lipid GO:0071396 145 0.030
apoptotic signaling pathway GO:0097190 306 0.030
negative regulation of protein phosphorylation GO:0001933 126 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
macromolecule catabolic process GO:0009057 281 0.028
leukocyte differentiation GO:0002521 342 0.027
regulation of transferase activity GO:0051338 263 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
organelle fission GO:0048285 170 0.027
muscle tissue development GO:0060537 308 0.027
negative regulation of defense response GO:0031348 77 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
regulation of cellular response to stress GO:0080135 159 0.026
positive regulation of protein modification process GO:0031401 299 0.026
protein localization to nucleus GO:0034504 121 0.026
nuclear division GO:0000280 158 0.026
immune effector process GO:0002252 321 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
regulation of antimicrobial humoral response GO:0002759 3 0.026
negative regulation of protein modification process GO:0031400 163 0.026
cellular response to dna damage stimulus GO:0006974 207 0.025
skeletal system development GO:0001501 356 0.025
glucose homeostasis GO:0042593 128 0.025
camera type eye development GO:0043010 266 0.025
regulation of mapk cascade GO:0043408 248 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
muscle cell differentiation GO:0042692 261 0.025
stem cell differentiation GO:0048863 268 0.025
regulation of jnk cascade GO:0046328 62 0.025
rhythmic process GO:0048511 174 0.025
chromatin modification GO:0016568 187 0.024
proteasomal protein catabolic process GO:0010498 98 0.024
forebrain development GO:0030900 302 0.024
cytoplasmic transport GO:0016482 234 0.024
response to acid chemical GO:0001101 111 0.023
digestive tract development GO:0048565 190 0.023
hormone secretion GO:0046879 128 0.023
placenta development GO:0001890 140 0.023
mitotic cell cycle process GO:1903047 159 0.023
regulation of lipid metabolic process GO:0019216 118 0.023
stem cell development GO:0048864 219 0.022
rna processing GO:0006396 105 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
peptide transport GO:0015833 133 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
response to oxidative stress GO:0006979 123 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
response to oxygen levels GO:0070482 62 0.021
development of primary sexual characteristics GO:0045137 143 0.021
heterocycle catabolic process GO:0046700 280 0.021
carbohydrate metabolic process GO:0005975 230 0.021
fertilization GO:0009566 127 0.021
circadian rhythm GO:0007623 114 0.021
learning or memory GO:0007611 148 0.021
cardiac ventricle development GO:0003231 83 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
single organism nuclear import GO:1902593 95 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.020
regulation of cell activation GO:0050865 289 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
transmission of nerve impulse GO:0019226 76 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
mrna metabolic process GO:0016071 84 0.020
lymphocyte differentiation GO:0030098 242 0.020
multicellular organism growth GO:0035264 161 0.020
blood vessel morphogenesis GO:0048514 285 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
spermatid development GO:0007286 108 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
positive regulation of hydrolase activity GO:0051345 148 0.019
translational initiation GO:0006413 24 0.019
regulation of system process GO:0044057 200 0.019
cell division GO:0051301 120 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
mitotic cell cycle GO:0000278 195 0.019
germ cell development GO:0007281 185 0.019
inflammatory response GO:0006954 244 0.019
respiratory tube development GO:0030323 167 0.019
wnt signaling pathway GO:0016055 188 0.019
actin cytoskeleton organization GO:0030036 220 0.019
regulation of membrane potential GO:0042391 192 0.019
cardiac chamber development GO:0003205 108 0.019
multicellular organismal signaling GO:0035637 91 0.019
embryonic placenta development GO:0001892 98 0.019
negative regulation of cytokine production GO:0001818 84 0.019
nuclear transport GO:0051169 139 0.018
bone development GO:0060348 120 0.018
regulation of translational initiation GO:0006446 15 0.018
cellular homeostasis GO:0019725 240 0.018
carbohydrate homeostasis GO:0033500 128 0.018
organ growth GO:0035265 117 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
fat cell differentiation GO:0045444 160 0.018
dna metabolic process GO:0006259 303 0.018
protein localization to organelle GO:0033365 185 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.017
cardiac muscle tissue development GO:0048738 130 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
regulation of organ morphogenesis GO:2000027 144 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
negative regulation of translational initiation GO:0045947 4 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
regulation of neuron death GO:1901214 134 0.017
action potential GO:0001508 78 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
cellular response to oxidative stress GO:0034599 76 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
regulation of reproductive process GO:2000241 66 0.017
regulation of multi organism process GO:0043900 111 0.017
regulation of secretion by cell GO:1903530 249 0.017
positive regulation of kinase activity GO:0033674 155 0.017
heterochromatin organization GO:0070828 4 0.017
jnk cascade GO:0007254 72 0.017
skin development GO:0043588 220 0.017
limb development GO:0060173 166 0.017
chromatin organization GO:0006325 206 0.017
regulation of cell cycle process GO:0010564 160 0.017
lung development GO:0030324 164 0.017
acetylcholine transport GO:0015870 2 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
myeloid cell differentiation GO:0030099 233 0.017
oocyte construction GO:0007308 2 0.016
muscle tissue morphogenesis GO:0060415 53 0.016
heart morphogenesis GO:0003007 178 0.016
spermatid differentiation GO:0048515 115 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
response to peptide hormone GO:0043434 127 0.016
regulation of hormone levels GO:0010817 211 0.016
erythrocyte differentiation GO:0030218 88 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
oxidation reduction process GO:0055114 342 0.016
positive regulation of organelle organization GO:0010638 128 0.016
aromatic compound catabolic process GO:0019439 286 0.016
organophosphate catabolic process GO:0046434 232 0.015
response to decreased oxygen levels GO:0036293 59 0.015
cardiac septum development GO:0003279 59 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
regulation of neuron projection development GO:0010975 169 0.015
cardiac ventricle morphogenesis GO:0003208 50 0.015
intracellular protein transport GO:0006886 204 0.015
mitochondrion organization GO:0007005 134 0.015
cellular response to acid chemical GO:0071229 68 0.015
ossification GO:0001503 216 0.015
myeloid cell homeostasis GO:0002262 114 0.015
protein maturation GO:0051604 176 0.015
muscle system process GO:0003012 141 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
t cell differentiation GO:0030217 174 0.015
gliogenesis GO:0042063 141 0.015
transmembrane transport GO:0055085 412 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
skeletal system morphogenesis GO:0048705 203 0.015
regulation of secretion GO:0051046 274 0.015
cell cycle checkpoint GO:0000075 47 0.015
dephosphorylation GO:0016311 129 0.014
protein import into nucleus GO:0006606 95 0.014
regulation of fat cell differentiation GO:0045598 81 0.014
digestive tract morphogenesis GO:0048546 147 0.014
cognition GO:0050890 149 0.014
response to light stimulus GO:0009416 135 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
skeletal muscle organ development GO:0060538 163 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
neuronal action potential GO:0019228 54 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of protein catabolic process GO:0042176 108 0.014
response to hypoxia GO:0001666 58 0.014
stress activated mapk cascade GO:0051403 80 0.014
t cell activation GO:0042110 289 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of peptide transport GO:0090087 91 0.014
regulation of organelle organization GO:0033043 289 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
regulation of circadian rhythm GO:0042752 58 0.014
protein import GO:0017038 101 0.013
connective tissue development GO:0061448 179 0.013
ras protein signal transduction GO:0007265 77 0.013
fatty acid metabolic process GO:0006631 121 0.013
positive regulation of jnk cascade GO:0046330 46 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
response to transforming growth factor beta GO:0071559 88 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
cation transport GO:0006812 399 0.013
nucleoside catabolic process GO:0009164 206 0.013
glycoprotein metabolic process GO:0009100 116 0.013
insulin secretion GO:0030073 89 0.013
glial cell differentiation GO:0010001 131 0.013
mrna processing GO:0006397 63 0.013
meiotic nuclear division GO:0007126 115 0.013
response to growth factor GO:0070848 198 0.013
bmp signaling pathway GO:0030509 93 0.013
maintenance of location GO:0051235 89 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
negative regulation of transferase activity GO:0051348 85 0.013
regulation of bmp signaling pathway GO:0030510 60 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
epithelial cell proliferation GO:0050673 174 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
regulation of ion transport GO:0043269 215 0.013
positive regulation of cell development GO:0010720 237 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
actin filament organization GO:0007015 113 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
lipid homeostasis GO:0055088 63 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
neurotransmitter secretion GO:0007269 62 0.013
response to temperature stimulus GO:0009266 55 0.013
axon ensheathment GO:0008366 76 0.012
regulation of map kinase activity GO:0043405 120 0.012
response to organic cyclic compound GO:0014070 198 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of jun kinase activity GO:0043506 40 0.012
b cell activation GO:0042113 161 0.012
regulation of binding GO:0051098 111 0.012
neuron death GO:0070997 154 0.012
cellular response to arsenic containing substance GO:0071243 4 0.012
heterochromatin assembly GO:0031507 2 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
compound eye development GO:0048749 1 0.012
blood circulation GO:0008015 195 0.012
cardiocyte differentiation GO:0035051 87 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
regulation of hydrolase activity GO:0051336 246 0.012
cartilage development GO:0051216 140 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.012
cell type specific apoptotic process GO:0097285 268 0.012
positive regulation of cytokine production GO:0001819 174 0.012
signal transduction involved in dna damage checkpoint GO:0072422 3 0.012
regulation of rna splicing GO:0043484 37 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.012
peptidyl serine modification GO:0018209 83 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
cellular amide metabolic process GO:0043603 58 0.012
response to peptide GO:1901652 136 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
placenta blood vessel development GO:0060674 31 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
respiratory system development GO:0060541 190 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
single fertilization GO:0007338 82 0.012
cellular response to peptide GO:1901653 92 0.012
response to radiation GO:0009314 165 0.011
sensory perception GO:0007600 245 0.011
renal system development GO:0072001 225 0.011
regulation of response to wounding GO:1903034 189 0.011
stem cell maintenance GO:0019827 130 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
positive regulation of transferase activity GO:0051347 167 0.011
appendage development GO:0048736 166 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
purine containing compound metabolic process GO:0072521 311 0.011
regulation of cell division GO:0051302 76 0.011
neural tube closure GO:0001843 90 0.011
regulation of translation GO:0006417 71 0.011
small molecule biosynthetic process GO:0044283 132 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
neural tube development GO:0021915 160 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
response to reactive oxygen species GO:0000302 56 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
gonad development GO:0008406 141 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
rna interference GO:0016246 2 0.011
developmental maturation GO:0021700 193 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
nuclear import GO:0051170 95 0.011
asymmetric stem cell division GO:0098722 3 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
innate immune response GO:0045087 157 0.011
epithelial tube formation GO:0072175 130 0.010
sensory system development GO:0048880 3 0.010
tissue homeostasis GO:0001894 115 0.010
protein targeting GO:0006605 143 0.010
regulation of protein import into nucleus GO:0042306 52 0.010
neurotransmitter transport GO:0006836 76 0.010
protein processing GO:0016485 163 0.010
muscle contraction GO:0006936 101 0.010
regulation of anatomical structure size GO:0090066 178 0.010
defecation GO:0030421 1 0.010
peptide hormone secretion GO:0030072 109 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
endocytosis GO:0006897 168 0.010
purine containing compound catabolic process GO:0072523 213 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
epithelial cell development GO:0002064 159 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
mesenchyme development GO:0060485 152 0.010
positive regulation of nervous system development GO:0051962 221 0.010
meiotic cell cycle GO:0051321 122 0.010
defense response to other organism GO:0098542 197 0.010
ribose phosphate metabolic process GO:0019693 291 0.010
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.010
p38mapk cascade GO:0038066 4 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
positive regulation of translational initiation GO:0045948 4 0.010
peptide secretion GO:0002790 114 0.010

Fam53a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
central nervous system disease DOID:331 0 0.016
musculoskeletal system disease DOID:17 0 0.013
disease of cellular proliferation DOID:14566 0 0.012
neurodegenerative disease DOID:1289 0 0.012
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011
muscular disease DOID:0080000 0 0.011
disease of metabolism DOID:0014667 0 0.010