Mus musculus

28 known processes

Ptgis

prostaglandin I2 (prostacyclin) synthase

(Aliases: Cyp8a1,Pgis,Cyp8)

Ptgis biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.273
cell adhesion GO:0007155 329 0.158
cellular amino acid metabolic process GO:0006520 103 0.146
regulation of hydrolase activity GO:0051336 246 0.136
cell substrate adhesion GO:0031589 130 0.128
bmp signaling pathway GO:0030509 93 0.128
regulation of cellular amine metabolic process GO:0033238 20 0.123
forebrain development GO:0030900 302 0.119
striated muscle tissue development GO:0014706 293 0.117
skeletal system morphogenesis GO:0048705 203 0.116
mapk cascade GO:0000165 281 0.112
regulation of cell adhesion GO:0030155 154 0.105
regulation of cellular amino acid metabolic process GO:0006521 5 0.104
cellular response to growth factor stimulus GO:0071363 197 0.104
epithelial tube morphogenesis GO:0060562 303 0.098
ossification GO:0001503 216 0.095
morphogenesis of a branching epithelium GO:0061138 193 0.095
blood vessel morphogenesis GO:0048514 285 0.094
Human
stem cell development GO:0048864 219 0.094
nucleoside phosphate metabolic process GO:0006753 338 0.093
regulation of cellular ketone metabolic process GO:0010565 66 0.090
regulation of vasculature development GO:1901342 88 0.086
Human
peptidyl amino acid modification GO:0018193 336 0.086
muscle tissue development GO:0060537 308 0.084
positive regulation of cell development GO:0010720 237 0.083
muscle system process GO:0003012 141 0.080
amine metabolic process GO:0009308 45 0.078
cellular chemical homeostasis GO:0055082 215 0.076
response to molecule of bacterial origin GO:0002237 143 0.076
regulation of mapk cascade GO:0043408 248 0.075
cellular ketone metabolic process GO:0042180 84 0.075
positive regulation of protein modification process GO:0031401 299 0.069
skeletal muscle organ development GO:0060538 163 0.069
bone development GO:0060348 120 0.068
response to growth factor GO:0070848 198 0.065
regulation of anatomical structure size GO:0090066 178 0.059
angiogenesis GO:0001525 201 0.059
Human
glucose homeostasis GO:0042593 128 0.058
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.057
positive regulation of protein phosphorylation GO:0001934 242 0.057
lung development GO:0030324 164 0.057
response to inorganic substance GO:0010035 96 0.057
actin cytoskeleton organization GO:0030036 220 0.057
cartilage development GO:0051216 140 0.056
small gtpase mediated signal transduction GO:0007264 97 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
telencephalon development GO:0021537 186 0.054
negative regulation of growth GO:0045926 99 0.054
skeletal system development GO:0001501 356 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
apoptotic signaling pathway GO:0097190 306 0.053
Human
negative regulation of cellular component organization GO:0051129 194 0.051
endocytosis GO:0006897 168 0.051
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.050
cation transport GO:0006812 399 0.050
response to lipopolysaccharide GO:0032496 128 0.049
anatomical structure homeostasis GO:0060249 145 0.049
camera type eye development GO:0043010 266 0.049
regulation of cellular response to stress GO:0080135 159 0.049
protein maturation GO:0051604 176 0.049
glycosyl compound metabolic process GO:1901657 246 0.049
regulation of vesicle mediated transport GO:0060627 139 0.048
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.048
positive regulation of mapk cascade GO:0043410 170 0.048
cell growth GO:0016049 130 0.048
response to transforming growth factor beta GO:0071559 88 0.047
positive regulation of hydrolase activity GO:0051345 148 0.047
limb morphogenesis GO:0035108 149 0.047
regulation of system process GO:0044057 200 0.046
regulation of cell projection organization GO:0031344 206 0.046
urogenital system development GO:0001655 261 0.045
Mouse
single organismal cell cell adhesion GO:0016337 131 0.044
branching morphogenesis of an epithelial tube GO:0048754 159 0.043
oxidation reduction process GO:0055114 342 0.043
Mouse
positive regulation of peptidase activity GO:0010952 49 0.043
single organism cell adhesion GO:0098602 156 0.042
positive regulation of nervous system development GO:0051962 221 0.041
purine nucleotide metabolic process GO:0006163 302 0.041
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.041
response to organic cyclic compound GO:0014070 198 0.040
regulation of hormone levels GO:0010817 211 0.040
regulation of neuron projection development GO:0010975 169 0.040
elastic fiber assembly GO:0048251 4 0.040
circulatory system process GO:0003013 197 0.040
synaptic transmission GO:0007268 329 0.040
ribose phosphate metabolic process GO:0019693 291 0.039
lymphocyte differentiation GO:0030098 242 0.039
smoothened signaling pathway GO:0007224 105 0.039
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.038
regulation of transferase activity GO:0051338 263 0.038
stem cell differentiation GO:0048863 268 0.038
actin filament organization GO:0007015 113 0.037
purine containing compound metabolic process GO:0072521 311 0.037
ameboidal type cell migration GO:0001667 128 0.037
negative regulation of cell development GO:0010721 169 0.037
negative regulation of molecular function GO:0044092 258 0.036
Human
regulation of cell motility GO:2000145 236 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
biomineral tissue development GO:0031214 64 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
cellular response to lipid GO:0071396 145 0.034
regulation of erk1 and erk2 cascade GO:0070372 71 0.034
transmembrane transport GO:0055085 412 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
epithelial cell development GO:0002064 159 0.034
regulation of body fluid levels GO:0050878 162 0.034
regulation of neuron differentiation GO:0045664 281 0.033
skin development GO:0043588 220 0.033
chemotaxis GO:0006935 247 0.033
epithelial cell proliferation GO:0050673 174 0.033
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
carbohydrate metabolic process GO:0005975 230 0.033
positive regulation of proteolysis GO:0045862 85 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
pallium development GO:0021543 120 0.032
negative regulation of phagocytosis GO:0050765 4 0.032
muscle cell differentiation GO:0042692 261 0.032
regulation of nucleotide metabolic process GO:0006140 169 0.032
developmental maturation GO:0021700 193 0.032
positive regulation of neuron differentiation GO:0045666 141 0.032
cellular lipid metabolic process GO:0044255 323 0.032
Human
regulation of proteolysis GO:0030162 164 0.031
regulation of cellular response to growth factor stimulus GO:0090287 82 0.031
regulation of organelle organization GO:0033043 289 0.031
bone morphogenesis GO:0060349 78 0.031
regulation of extent of cell growth GO:0061387 52 0.031
connective tissue development GO:0061448 179 0.031
respiratory tube development GO:0030323 167 0.030
purine containing compound catabolic process GO:0072523 213 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
cellular homeostasis GO:0019725 240 0.030
transmission of nerve impulse GO:0019226 76 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
wound healing GO:0042060 157 0.030
cardiac chamber development GO:0003205 108 0.030
regulation of cell growth GO:0001558 91 0.030
metal ion homeostasis GO:0055065 189 0.030
monocarboxylic acid metabolic process GO:0032787 191 0.029
Human Mouse
morphogenesis of a branching structure GO:0001763 203 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
activation of immune response GO:0002253 138 0.028
regulation of cell cycle process GO:0010564 160 0.028
positive regulation of cell migration GO:0030335 109 0.028
cell type specific apoptotic process GO:0097285 268 0.028
nucleotide metabolic process GO:0009117 332 0.028
tube formation GO:0035148 140 0.028
regulation of endocytosis GO:0030100 69 0.028
nucleoside metabolic process GO:0009116 246 0.028
protein localization to membrane GO:0072657 108 0.027
appendage development GO:0048736 166 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.027
gland development GO:0048732 330 0.027
Mouse
aromatic compound catabolic process GO:0019439 286 0.027
regulation of cytokine production GO:0001817 266 0.027
immune effector process GO:0002252 321 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
regulation of membrane potential GO:0042391 192 0.027
renal system development GO:0072001 225 0.027
digestive system development GO:0055123 200 0.027
regulation of kinase activity GO:0043549 249 0.027
embryonic appendage morphogenesis GO:0035113 126 0.027
organonitrogen compound catabolic process GO:1901565 264 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
embryonic organ morphogenesis GO:0048562 276 0.026
locomotory behavior GO:0007626 195 0.026
sensory organ morphogenesis GO:0090596 242 0.026
nucleoside catabolic process GO:0009164 206 0.026
regulation of secretion by cell GO:1903530 249 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
neuronal action potential GO:0019228 54 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
regulation of secretion GO:0051046 274 0.025
nucleoside phosphate catabolic process GO:1901292 222 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
negative regulation of cell growth GO:0030308 44 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.025
Mouse
ribonucleotide catabolic process GO:0009261 208 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
regulation of map kinase activity GO:0043405 120 0.025
divalent metal ion transport GO:0070838 172 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
respiratory system development GO:0060541 190 0.025
myosin filament organization GO:0031033 3 0.025
multicellular organism growth GO:0035264 161 0.025
extracellular matrix organization GO:0030198 147 0.024
organelle localization GO:0051640 179 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
mesenchyme development GO:0060485 152 0.024
regulation of peptidase activity GO:0052547 96 0.024
heart morphogenesis GO:0003007 178 0.024
nucleotide catabolic process GO:0009166 217 0.024
cellular response to oxidative stress GO:0034599 76 0.024
positive regulation of cell death GO:0010942 224 0.024
Human
regulation of cell substrate adhesion GO:0010810 73 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
muscle cell development GO:0055001 133 0.023
t cell activation GO:0042110 289 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
regulation of muscle tissue development GO:1901861 97 0.023
regulation of cellular component size GO:0032535 121 0.023
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.023
regulation of cell migration GO:0030334 219 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
anion transport GO:0006820 177 0.023
myeloid cell differentiation GO:0030099 233 0.023
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.023
cellular response to inorganic substance GO:0071241 37 0.023
vascular process in circulatory system GO:0003018 62 0.022
regulation of homeostatic process GO:0032844 182 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
regulation of striated muscle cell differentiation GO:0051153 81 0.022
chondrocyte differentiation GO:0002062 72 0.022
membrane organization GO:0061024 245 0.022
blood circulation GO:0008015 195 0.022
carbohydrate homeostasis GO:0033500 128 0.022
glycoprotein biosynthetic process GO:0009101 89 0.022
positive regulation of cell adhesion GO:0045785 80 0.022
positive regulation of behavior GO:0048520 40 0.022
ras protein signal transduction GO:0007265 77 0.022
sensory perception of mechanical stimulus GO:0050954 107 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.022
protein localization to organelle GO:0033365 185 0.022
cellular protein complex assembly GO:0043623 116 0.022
small molecule biosynthetic process GO:0044283 132 0.021
Human Mouse
protein localization to plasma membrane GO:0072659 57 0.021
lipid biosynthetic process GO:0008610 179 0.021
Human Mouse
regulation of removal of superoxide radicals GO:2000121 4 0.021
negative regulation of neuron differentiation GO:0045665 101 0.021
regulation of response to wounding GO:1903034 189 0.021
Human
actomyosin structure organization GO:0031032 56 0.021
wnt signaling pathway GO:0016055 188 0.021
regulation of ossification GO:0030278 112 0.021
neurotransmitter transport GO:0006836 76 0.021
regulation of protein localization GO:0032880 231 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
regulation of bmp signaling pathway GO:0030510 60 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
axonogenesis GO:0007409 274 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
peptidyl tyrosine phosphorylation GO:0018108 143 0.021
immune response activating signal transduction GO:0002757 116 0.020
neuron migration GO:0001764 122 0.020
fatty acid metabolic process GO:0006631 121 0.020
Human
cellular response to biotic stimulus GO:0071216 92 0.020
extracellular structure organization GO:0043062 148 0.020
sequestering of metal ion GO:0051238 19 0.020
ear development GO:0043583 200 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
erk1 and erk2 cascade GO:0070371 77 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
leukocyte differentiation GO:0002521 342 0.020
kidney development GO:0001822 213 0.020
sequestering of calcium ion GO:0051208 18 0.020
tissue homeostasis GO:0001894 115 0.020
monosaccharide metabolic process GO:0005996 106 0.020
nitrogen compound transport GO:0071705 271 0.020
mesenchymal cell differentiation GO:0048762 107 0.019
sensory perception GO:0007600 245 0.019
cardiac muscle tissue development GO:0048738 130 0.019
positive regulation of chemotaxis GO:0050921 38 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
lipid transport GO:0006869 98 0.019
myotube differentiation GO:0014902 105 0.019
fat cell differentiation GO:0045444 160 0.019
calcium ion homeostasis GO:0055074 127 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
maintenance of location GO:0051235 89 0.019
regulation of angiogenesis GO:0045765 81 0.019
Human
regulation of actin filament based process GO:0032970 99 0.019
eye photoreceptor cell development GO:0042462 31 0.019
macromolecule catabolic process GO:0009057 281 0.019
embryonic placenta development GO:0001892 98 0.019
organic hydroxy compound biosynthetic process GO:1901617 77 0.019
Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.019
negative regulation of ossification GO:0030279 49 0.019
regulation of muscle system process GO:0090257 80 0.019
cerebral cortex development GO:0021987 86 0.019
actin mediated cell contraction GO:0070252 15 0.019
regulation of cell size GO:0008361 72 0.019
regulation of chemotaxis GO:0050920 53 0.018
protein localization to nucleus GO:0034504 121 0.018
protein processing GO:0016485 163 0.018
heterocycle catabolic process GO:0046700 280 0.018
carboxylic acid transport GO:0046942 100 0.018
muscle fiber development GO:0048747 76 0.018
meiotic nuclear division GO:0007126 115 0.018
developmental cell growth GO:0048588 84 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
Human
mitotic cell cycle GO:0000278 195 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
positive regulation of kinase activity GO:0033674 155 0.018
organic anion transport GO:0015711 137 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
negative regulation of nervous system development GO:0051961 156 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
cytokine production GO:0001816 319 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
meiotic cell cycle GO:0051321 122 0.018
response to radiation GO:0009314 165 0.018
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.018
neuron death GO:0070997 154 0.018
response to organonitrogen compound GO:0010243 246 0.018
glycoprotein metabolic process GO:0009100 116 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
purine nucleoside metabolic process GO:0042278 241 0.017
skeletal muscle cell differentiation GO:0035914 66 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
response to oxidative stress GO:0006979 123 0.017
stem cell maintenance GO:0019827 130 0.017
peptidyl serine modification GO:0018209 83 0.017
cardiac chamber morphogenesis GO:0003206 93 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
neuron projection extension GO:1990138 64 0.017
intracellular protein transport GO:0006886 204 0.017
cation homeostasis GO:0055080 212 0.017
regulation of action potential GO:0098900 4 0.017
negative regulation of cell adhesion GO:0007162 45 0.017
innate immune response GO:0045087 157 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
alcohol metabolic process GO:0006066 116 0.017
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.017
tissue remodeling GO:0048771 102 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
negative regulation of phospholipase activity GO:0010519 4 0.017
regulation of organ morphogenesis GO:2000027 144 0.017
positive regulation of cell motility GO:2000147 116 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
lymphocyte proliferation GO:0046651 164 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
neurotransmitter secretion GO:0007269 62 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.016
regionalization GO:0003002 337 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
skeletal muscle fiber development GO:0048741 58 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
action potential GO:0001508 78 0.016
regulation of tumor necrosis factor production GO:0032680 49 0.016
placenta development GO:0001890 140 0.016
positive regulation of cell cycle GO:0045787 92 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
positive regulation of transferase activity GO:0051347 167 0.016
regulation of protein kinase b signaling GO:0051896 56 0.016
response to reactive oxygen species GO:0000302 56 0.016
calcium ion transport GO:0006816 159 0.016
forebrain cell migration GO:0021885 58 0.016
regulation of cellular response to oxidative stress GO:1900407 19 0.016
epithelial cell morphogenesis GO:0003382 41 0.016
cell activation involved in immune response GO:0002263 126 0.016
phagocytosis GO:0006909 66 0.016
regulation of protein kinase activity GO:0045859 232 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
Mouse
bone mineralization GO:0030282 54 0.016
mesenchymal cell development GO:0014031 93 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
Human
ion transmembrane transport GO:0034220 361 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.015
hormone metabolic process GO:0042445 86 0.015
b cell activation GO:0042113 161 0.015
positive regulation of cytokine production GO:0001819 174 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
cellular ion homeostasis GO:0006873 165 0.015
positive regulation of growth GO:0045927 104 0.015
regulation of osteoblast differentiation GO:0045667 67 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
regulation of cell cycle GO:0051726 281 0.015
regulation of intracellular protein transport GO:0033157 82 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
skeletal myofibril assembly GO:0014866 4 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
striated muscle cell development GO:0055002 125 0.015
regulation of receptor activity GO:0010469 41 0.015
photoreceptor cell differentiation GO:0046530 52 0.015
eye photoreceptor cell differentiation GO:0001754 41 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
mitochondrion organization GO:0007005 134 0.015
regulation of t cell activation GO:0050863 170 0.015
multicellular organismal signaling GO:0035637 91 0.015
cytoplasmic transport GO:0016482 234 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
lipid localization GO:0010876 126 0.015
spermatogenesis GO:0007283 284 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
metanephros development GO:0001656 79 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
protein ubiquitination GO:0016567 171 0.015
protein import GO:0017038 101 0.015
regulation of neurotransmitter levels GO:0001505 87 0.014
organelle fission GO:0048285 170 0.014
organic hydroxy compound transport GO:0015850 93 0.014
compound eye development GO:0048749 1 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
organic acid transport GO:0015849 101 0.014
actin filament based movement GO:0030048 23 0.014
leukocyte migration GO:0050900 124 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
negative regulation of cell projection organization GO:0031345 56 0.014
photoreceptor cell development GO:0042461 40 0.014
dendrite development GO:0016358 115 0.014
rhythmic process GO:0048511 174 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
monosaccharide transport GO:0015749 58 0.014
acetylcholine transport GO:0015870 2 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
positive regulation of phospholipase activity GO:0010518 3 0.014
endomembrane system organization GO:0010256 147 0.014
response to steroid hormone GO:0048545 56 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
mesonephric tubule development GO:0072164 94 0.014
organelle assembly GO:0070925 177 0.014
hormone secretion GO:0046879 128 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
adaptive immune response GO:0002250 155 0.014
ventricular septum development GO:0003281 42 0.014
positive regulation of neuron projection development GO:0010976 79 0.014
divalent inorganic cation transport GO:0072511 178 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
striated muscle myosin thick filament assembly GO:0071688 1 0.013
limbic system development GO:0021761 72 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
positive regulation of organelle organization GO:0010638 128 0.013
response to nutrient levels GO:0031667 109 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
glucose metabolic process GO:0006006 92 0.013
cell recognition GO:0008037 83 0.013
peptidyl serine phosphorylation GO:0018105 74 0.013
cellular protein catabolic process GO:0044257 155 0.013
neuromuscular process GO:0050905 99 0.013
gtp metabolic process GO:0046039 144 0.013
positive regulation of endocytosis GO:0045807 42 0.013
defense response to bacterium GO:0042742 119 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
adult locomotory behavior GO:0008344 91 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of dendritic cell chemotaxis GO:2000508 1 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
positive regulation of epithelial cell proliferation GO:0050679 68 0.013
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
organophosphate catabolic process GO:0046434 232 0.013
hindbrain development GO:0030902 128 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of protein processing GO:0070613 96 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
Mouse
male gamete generation GO:0048232 285 0.012
response to fibroblast growth factor GO:0071774 47 0.012
acetate ester transport GO:1901374 2 0.012
learning or memory GO:0007611 148 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
microtubule based process GO:0007017 236 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
digestive tract development GO:0048565 190 0.012
negative regulation of cytokine production GO:0001818 84 0.012
regulation of multi organism process GO:0043900 111 0.012
positive regulation of muscle cell differentiation GO:0051149 39 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
neural precursor cell proliferation GO:0061351 121 0.012
mitotic cell cycle process GO:1903047 159 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
covalent chromatin modification GO:0016569 163 0.012
chromatin organization GO:0006325 206 0.012
erythrocyte differentiation GO:0030218 88 0.012
regulation of cell activation GO:0050865 289 0.012
ureteric bud development GO:0001657 94 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of axon extension GO:0030516 43 0.012
insulin processing GO:0030070 2 0.012
cellular glucose homeostasis GO:0001678 52 0.012
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
cellular response to external stimulus GO:0071496 88 0.012
carbohydrate transport GO:0008643 62 0.012

Ptgis disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
Human
musculoskeletal system disease DOID:17 0 0.064
nervous system disease DOID:863 0 0.041
sensory system disease DOID:0050155 0 0.034
cardiovascular system disease DOID:1287 0 0.020
Human
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.018
connective tissue disease DOID:65 0 0.014
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013