Mus musculus

0 known processes

Clcn4-2

chloride channel 4-2

(Aliases: Clc4-2,MGC117899,Clcn4)

Clcn4-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing small molecule metabolic process GO:0055086 352 0.079
regulation of cell growth GO:0001558 91 0.066
exocytosis GO:0006887 121 0.065
cellular amino acid metabolic process GO:0006520 103 0.062
cellular macromolecule catabolic process GO:0044265 206 0.060
regulation of neuron differentiation GO:0045664 281 0.059
positive regulation of neuron projection development GO:0010976 79 0.058
synaptic transmission GO:0007268 329 0.058
positive regulation of neuron differentiation GO:0045666 141 0.057
regulation of membrane potential GO:0042391 192 0.056
ribonucleoside triphosphate catabolic process GO:0009203 199 0.055
positive regulation of cell development GO:0010720 237 0.055
regulation of neuron projection development GO:0010975 169 0.054
regulation of extent of cell growth GO:0061387 52 0.051
nucleoside phosphate metabolic process GO:0006753 338 0.051
positive regulation of nervous system development GO:0051962 221 0.049
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.049
synaptic vesicle localization GO:0097479 59 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
ribose phosphate metabolic process GO:0019693 291 0.048
transmission of nerve impulse GO:0019226 76 0.047
regulation of cell projection organization GO:0031344 206 0.047
purine ribonucleotide metabolic process GO:0009150 290 0.047
aromatic compound catabolic process GO:0019439 286 0.046
organonitrogen compound catabolic process GO:1901565 264 0.046
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.045
gtp metabolic process GO:0046039 144 0.045
apoptotic signaling pathway GO:0097190 306 0.044
mapk cascade GO:0000165 281 0.043
regulation of cellular response to stress GO:0080135 159 0.043
glycosyl compound catabolic process GO:1901658 206 0.042
ion transmembrane transport GO:0034220 361 0.042
Human Yeast
cellular protein catabolic process GO:0044257 155 0.041
ribonucleotide catabolic process GO:0009261 208 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
cell growth GO:0016049 130 0.040
positive regulation of protein modification process GO:0031401 299 0.038
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.038
action potential GO:0001508 78 0.038
organic cyclic compound catabolic process GO:1901361 295 0.037
cellular amine metabolic process GO:0044106 44 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
regulation of cellular catabolic process GO:0031329 242 0.036
establishment of vesicle localization GO:0051650 81 0.036
peptidyl amino acid modification GO:0018193 336 0.036
cell adhesion GO:0007155 329 0.035
gtp catabolic process GO:0006184 143 0.035
dna metabolic process GO:0006259 303 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.035
transmembrane transport GO:0055085 412 0.034
Human Yeast
positive regulation of cell projection organization GO:0031346 95 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
purine containing compound metabolic process GO:0072521 311 0.033
heterocycle catabolic process GO:0046700 280 0.033
macromolecule catabolic process GO:0009057 281 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.033
inorganic ion transmembrane transport GO:0098660 234 0.033
Human Yeast
amine metabolic process GO:0009308 45 0.033
nucleotide catabolic process GO:0009166 217 0.033
organelle localization GO:0051640 179 0.032
multicellular organismal signaling GO:0035637 91 0.032
regulation of secretion GO:0051046 274 0.032
nucleotide metabolic process GO:0009117 332 0.032
lipid biosynthetic process GO:0008610 179 0.032
neuronal action potential GO:0019228 54 0.032
nucleoside metabolic process GO:0009116 246 0.032
regulation of transferase activity GO:0051338 263 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
ribonucleoside metabolic process GO:0009119 245 0.031
cellular response to starvation GO:0009267 57 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
learning or memory GO:0007611 148 0.031
membrane organization GO:0061024 245 0.031
Mouse
regulation of cell size GO:0008361 72 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
vacuole organization GO:0007033 38 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.030
establishment of synaptic vesicle localization GO:0097480 57 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
vesicle localization GO:0051648 86 0.029
cellular response to growth factor stimulus GO:0071363 197 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
endocytosis GO:0006897 168 0.029
Mouse
mitochondrion distribution GO:0048311 4 0.028
positive regulation of transferase activity GO:0051347 167 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
microtubule based process GO:0007017 236 0.028
synaptic vesicle transport GO:0048489 57 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
cognition GO:0050890 149 0.027
regulation of mapk cascade GO:0043408 248 0.027
cellular response to organonitrogen compound GO:0071417 145 0.027
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
negative regulation of growth GO:0045926 99 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
regulation of kinase activity GO:0043549 249 0.024
developmental cell growth GO:0048588 84 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
vesicle organization GO:0016050 60 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
cell type specific apoptotic process GO:0097285 268 0.023
chemotaxis GO:0006935 247 0.023
glycerolipid metabolic process GO:0046486 122 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
anion transport GO:0006820 177 0.023
Human Yeast
cellular ketone metabolic process GO:0042180 84 0.023
regulation of synaptic plasticity GO:0048167 87 0.023
macroautophagy GO:0016236 21 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
endomembrane system organization GO:0010256 147 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
neuron death GO:0070997 154 0.022
establishment of organelle localization GO:0051656 122 0.022
purine containing compound catabolic process GO:0072523 213 0.022
protein localization to organelle GO:0033365 185 0.022
extracellular matrix organization GO:0030198 147 0.022
cellular response to biotic stimulus GO:0071216 92 0.022
regulation of secretion by cell GO:1903530 249 0.022
retrograde transport endosome to golgi GO:0042147 2 0.021
regulation of cellular component size GO:0032535 121 0.021
cell division GO:0051301 120 0.021
leukocyte differentiation GO:0002521 342 0.021
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.021
organophosphate catabolic process GO:0046434 232 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
regulation of organelle organization GO:0033043 289 0.021
response to nutrient levels GO:0031667 109 0.021
regulation of neurotrophin trk receptor signaling pathway GO:0051386 4 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
response to growth factor GO:0070848 198 0.020
regulation of axon extension GO:0030516 43 0.020
positive regulation of mapk cascade GO:0043410 170 0.019
response to extracellular stimulus GO:0009991 127 0.019
regulation of postsynaptic membrane potential GO:0060078 48 0.019
nucleoside catabolic process GO:0009164 206 0.019
regulation of protein localization GO:0032880 231 0.019
golgi to endosome transport GO:0006895 3 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
nitrogen compound transport GO:0071705 271 0.018
protein catabolic process GO:0030163 221 0.018
germ cell development GO:0007281 185 0.018
macromolecule glycosylation GO:0043413 55 0.018
cation transport GO:0006812 399 0.018
positive regulation of cell growth GO:0030307 33 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
fertilization GO:0009566 127 0.017
organelle assembly GO:0070925 177 0.017
neuron apoptotic process GO:0051402 142 0.017
ensheathment of neurons GO:0007272 76 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
positive regulation of growth GO:0045927 104 0.017
cellular response to nutrient levels GO:0031669 64 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
homeostasis of number of cells GO:0048872 210 0.017
protein acylation GO:0043543 64 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
mitochondrion organization GO:0007005 134 0.017
regulation of body fluid levels GO:0050878 162 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
compound eye development GO:0048749 1 0.017
adult locomotory behavior GO:0008344 91 0.017
wnt signaling pathway GO:0016055 188 0.017
membrane depolarization GO:0051899 64 0.017
regulation of neurotransmitter levels GO:0001505 87 0.017
positive regulation of cell death GO:0010942 224 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
stem cell development GO:0048864 219 0.016
myelination GO:0042552 74 0.016
axonogenesis GO:0007409 274 0.016
cerebellar cortex formation GO:0021697 22 0.016
negative regulation of cell development GO:0010721 169 0.016
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.016
positive regulation of kinase activity GO:0033674 155 0.016
translation GO:0006412 93 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
establishment of mitochondrion localization GO:0051654 4 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
positive regulation of secretion GO:0051047 130 0.016
cellular response to external stimulus GO:0071496 88 0.016
regulation of hydrolase activity GO:0051336 246 0.016
glycerolipid biosynthetic process GO:0045017 50 0.016
stem cell differentiation GO:0048863 268 0.016
pole plasm assembly GO:0007315 2 0.016
fat cell differentiation GO:0045444 160 0.016
glycoprotein biosynthetic process GO:0009101 89 0.015
protein ubiquitination GO:0016567 171 0.015
axon ensheathment GO:0008366 76 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
myeloid leukocyte activation GO:0002274 83 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
forebrain development GO:0030900 302 0.015
dendrite development GO:0016358 115 0.015
histone h4 k16 acetylation GO:0043984 3 0.015
peptidyl lysine modification GO:0018205 77 0.015
regulation of neuron death GO:1901214 134 0.015
intracellular protein transport GO:0006886 204 0.015
developmental maturation GO:0021700 193 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
organic hydroxy compound transport GO:0015850 93 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
telencephalon development GO:0021537 186 0.015
lateral inhibition GO:0046331 1 0.015
regulation of anatomical structure size GO:0090066 178 0.015
smoothened signaling pathway GO:0007224 105 0.015
glycerophospholipid metabolic process GO:0006650 71 0.014
meiotic cell cycle process GO:1903046 77 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
regulation of cell motility GO:2000145 236 0.014
lipid transport GO:0006869 98 0.014
male gamete generation GO:0048232 285 0.014
gland development GO:0048732 330 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
cation homeostasis GO:0055080 212 0.014
Yeast
regulation of ossification GO:0030278 112 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of protein kinase activity GO:0045859 232 0.014
inflammatory response GO:0006954 244 0.014
organelle fission GO:0048285 170 0.014
cellular response to acid chemical GO:0071229 68 0.014
negative regulation of cellular catabolic process GO:0031330 47 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
leukocyte mediated immunity GO:0002443 174 0.014
cytokine production GO:0001816 319 0.014
synapse organization GO:0050808 125 0.013
meiotic nuclear division GO:0007126 115 0.013
mesoderm morphogenesis GO:0048332 64 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
cyclic nucleotide metabolic process GO:0009187 59 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
dephosphorylation GO:0016311 129 0.013
negative regulation of cell growth GO:0030308 44 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
camera type eye development GO:0043010 266 0.013
skeletal system development GO:0001501 356 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
anatomical structure homeostasis GO:0060249 145 0.013
endodermal cell fate specification GO:0001714 4 0.013
regulation of exocytosis GO:0017157 61 0.013
regulation of cell activation GO:0050865 289 0.013
lymphocyte differentiation GO:0030098 242 0.013
single fertilization GO:0007338 82 0.013
lipid localization GO:0010876 126 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
regulation of homeostatic process GO:0032844 182 0.012
protein localization to membrane GO:0072657 108 0.012
sulfur compound metabolic process GO:0006790 100 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
rho protein signal transduction GO:0007266 32 0.012
locomotory behavior GO:0007626 195 0.012
carbohydrate metabolic process GO:0005975 230 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
negative regulation of molecular function GO:0044092 258 0.012
response to inorganic substance GO:0010035 96 0.012
response to starvation GO:0042594 65 0.012
cellular chemical homeostasis GO:0055082 215 0.012
Yeast
cellular metal ion homeostasis GO:0006875 151 0.012
Yeast
cerebellum morphogenesis GO:0021587 42 0.012
cellular response to lipid GO:0071396 145 0.012
neurotransmitter secretion GO:0007269 62 0.012
glycoprotein metabolic process GO:0009100 116 0.012
male genitalia morphogenesis GO:0048808 4 0.012
response to light stimulus GO:0009416 135 0.012
learning GO:0007612 98 0.012
organic anion transport GO:0015711 137 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
sequestering of calcium ion GO:0051208 18 0.012
divalent inorganic cation transport GO:0072511 178 0.012
cytoplasmic transport GO:0016482 234 0.011
digestive tract development GO:0048565 190 0.011
neuron projection extension GO:1990138 64 0.011
regulation of ion transport GO:0043269 215 0.011
Yeast
response to endoplasmic reticulum stress GO:0034976 53 0.011
ras protein signal transduction GO:0007265 77 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
muscle adaptation GO:0043500 39 0.011
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.011
meiotic cell cycle GO:0051321 122 0.011
extracellular structure organization GO:0043062 148 0.011
connective tissue development GO:0061448 179 0.011
gastrulation GO:0007369 116 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.011
regulation of proteolysis GO:0030162 164 0.011
cellular homeostasis GO:0019725 240 0.011
Yeast
neurotransmitter transport GO:0006836 76 0.011
t cell activation GO:0042110 289 0.011
pharynx development GO:0060465 1 0.011
lung development GO:0030324 164 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
synapsis GO:0007129 34 0.011
response to fibroblast growth factor GO:0071774 47 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
immune effector process GO:0002252 321 0.011
ossification GO:0001503 216 0.011
nuclear division GO:0000280 158 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
cerebellar granular layer development GO:0021681 13 0.011
cellular ion homeostasis GO:0006873 165 0.011
Yeast
cellular lipid metabolic process GO:0044255 323 0.011
axon cargo transport GO:0008088 33 0.010
cell fate commitment GO:0045165 210 0.010
cell differentiation in hindbrain GO:0021533 24 0.010
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
regulation of transmembrane transport GO:0034762 128 0.010
Yeast
dna modification GO:0006304 50 0.010
sequestering of metal ion GO:0051238 19 0.010
guanosine containing compound metabolic process GO:1901068 144 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
endoderm development GO:0007492 45 0.010
response to organonitrogen compound GO:0010243 246 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
cerebellum development GO:0021549 77 0.010
inter male aggressive behavior GO:0002121 3 0.010
microtubule based movement GO:0007018 84 0.010

Clcn4-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
disease of anatomical entity DOID:7 0 0.027
musculoskeletal system disease DOID:17 0 0.027
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.020
central nervous system disease DOID:331 0 0.016
bone development disease DOID:0080006 0 0.015
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
immune system disease DOID:2914 0 0.011
brain disease DOID:936 0 0.010