Mus musculus

65 known processes

Myl2

myosin, light polypeptide 2, regulatory, cardiac, slow

(Aliases: Mylpc,MLC-2v,MLC-2,Mlc2v)

Myl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ventricular cardiac muscle cell action potential GO:0086005 4 0.999
striated muscle contraction GO:0006941 45 0.998
cardiac muscle cell contraction GO:0086003 7 0.998
muscle contraction GO:0006936 101 0.998
regulation of muscle system process GO:0090257 80 0.996
Worm
heart process GO:0003015 94 0.996
striated muscle tissue development GO:0014706 293 0.996
av node cell to bundle of his cell communication GO:0086067 2 0.995
heart contraction GO:0060047 93 0.995
muscle cell development GO:0055001 133 0.994
atrial ventricular junction remodeling GO:0003294 2 0.994
cardiac myofibril assembly GO:0055003 12 0.994
regulation of heart contraction GO:0008016 77 0.993
striated muscle cell development GO:0055002 125 0.993
muscle adaptation GO:0043500 39 0.992
heart morphogenesis GO:0003007 178 0.992
cardiac muscle tissue morphogenesis GO:0055008 44 0.992
cardiac muscle tissue development GO:0048738 130 0.992
actin filament based movement GO:0030048 23 0.991
cardiocyte differentiation GO:0035051 87 0.990
muscle tissue development GO:0060537 308 0.990
cardiac muscle contraction GO:0060048 32 0.989
cardiac muscle cell development GO:0055013 39 0.989
regulation of muscle contraction GO:0006937 49 0.982
Worm
actomyosin structure organization GO:0031032 56 0.980
skeletal muscle adaptation GO:0043501 16 0.977
cardiac chamber morphogenesis GO:0003206 93 0.977
regulation of cardiac muscle contraction GO:0055117 21 0.974
striated muscle myosin thick filament assembly GO:0071688 1 0.973
sarcomere organization GO:0045214 24 0.969
regulation of striated muscle contraction GO:0006942 25 0.968
cell communication involved in cardiac conduction GO:0086065 9 0.961
blood circulation GO:0008015 195 0.959
purine nucleotide metabolic process GO:0006163 302 0.958
actin mediated cell contraction GO:0070252 15 0.956
regulation of blood circulation GO:1903522 93 0.955
muscle cell differentiation GO:0042692 261 0.954
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.954
muscle fiber development GO:0048747 76 0.950
circulatory system process GO:0003013 197 0.948
regulation of system process GO:0044057 200 0.944
Worm
muscle tissue morphogenesis GO:0060415 53 0.940
skeletal system development GO:0001501 356 0.938
myosin filament organization GO:0031033 3 0.934
ventricular cardiac myofibril assembly GO:0055005 3 0.933
regulation of muscle adaptation GO:0043502 31 0.932
organonitrogen compound catabolic process GO:1901565 264 0.931
cardiac conduction GO:0061337 17 0.929
heart trabecula formation GO:0060347 14 0.927
muscle system process GO:0003012 141 0.920
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 0.919
skeletal muscle fiber development GO:0048741 58 0.914
regulation of atp metabolic process GO:1903578 17 0.912
embryonic heart tube morphogenesis GO:0003143 51 0.904
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.901
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.901
embryonic heart tube development GO:0035050 65 0.897
regulation of atp catabolic process GO:1903289 9 0.890
regulation of cardiac muscle cell contraction GO:0086004 11 0.877
ribonucleotide metabolic process GO:0009259 291 0.875
cardiac chamber development GO:0003205 108 0.872
myofibril assembly GO:0030239 34 0.865
regulation of hydrolase activity GO:0051336 246 0.862
regulation of nucleotide catabolic process GO:0030811 122 0.860
purine nucleoside metabolic process GO:0042278 241 0.850
response to oxygen levels GO:0070482 62 0.848
nucleoside monophosphate metabolic process GO:0009123 85 0.845
transition between fast and slow fiber GO:0014883 9 0.844
regulation of purine nucleotide metabolic process GO:1900542 169 0.835
purine containing compound metabolic process GO:0072521 311 0.834
cardiac ventricle morphogenesis GO:0003208 50 0.833
cardiac muscle fiber development GO:0048739 4 0.833
cardiac muscle cell differentiation GO:0055007 69 0.822
cardiac muscle cell action potential involved in contraction GO:0086002 6 0.817
regulation of heart rate GO:0002027 36 0.807
cardiac ventricle development GO:0003231 83 0.806
positive regulation of transcription via serum response element binding GO:0010735 1 0.805
actin cytoskeleton organization GO:0030036 220 0.801
regulation of cardiac muscle cell proliferation GO:0060043 23 0.799
response to inactivity GO:0014854 4 0.794
myosin filament assembly GO:0031034 2 0.794
purine containing compound catabolic process GO:0072523 213 0.791
cellular metal ion homeostasis GO:0006875 151 0.789
positive regulation of cardioblast differentiation GO:0051891 3 0.785
embryonic organ morphogenesis GO:0048562 276 0.785
ribonucleoside catabolic process GO:0042454 206 0.785
sequestering of calcium ion GO:0051208 18 0.780
regulation of action potential GO:0098900 4 0.774
camera type eye development GO:0043010 266 0.771
milk ejection GO:0060156 1 0.762
atrial cardiac muscle cell differentiation GO:0055011 2 0.759
ribonucleotide catabolic process GO:0009261 208 0.758
regulation of the force of heart contraction GO:0002026 17 0.757
nucleoside phosphate metabolic process GO:0006753 338 0.745
regulation of membrane depolarization GO:0003254 11 0.745
mitochondrion organization GO:0007005 134 0.742
organ growth GO:0035265 117 0.737
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.735
atp metabolic process GO:0046034 75 0.734
purine ribonucleotide metabolic process GO:0009150 290 0.733
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.730
atrial cardiac muscle cell development GO:0055014 2 0.730
sa node cell action potential GO:0086015 4 0.720
regulation of cellular catabolic process GO:0031329 242 0.717
foramen ovale closure GO:0035922 1 0.717
ribonucleoside triphosphate catabolic process GO:0009203 199 0.714
purine nucleotide catabolic process GO:0006195 211 0.706
regulation of nucleoside metabolic process GO:0009118 130 0.702
ventricular cardiac muscle tissue development GO:0003229 38 0.702
purine nucleoside triphosphate metabolic process GO:0009144 226 0.699
regulation of purine nucleotide catabolic process GO:0033121 122 0.693
cardiac cell development GO:0055006 41 0.693
bundle of his development GO:0003166 4 0.686
ribonucleoside monophosphate catabolic process GO:0009158 57 0.681
regulation of skeletal muscle adaptation GO:0014733 12 0.678
glycosyl compound catabolic process GO:1901658 206 0.674
nucleotide catabolic process GO:0009166 217 0.673
cardiac muscle cell action potential GO:0086001 11 0.666
nucleoside phosphate catabolic process GO:1901292 222 0.662
embryonic placenta development GO:0001892 98 0.653
heterocycle catabolic process GO:0046700 280 0.652
regulation of membrane depolarization during cardiac muscle cell action potential GO:1900825 1 0.648
nucleoside metabolic process GO:0009116 246 0.647
response to fibroblast growth factor GO:0071774 47 0.646
purine ribonucleoside metabolic process GO:0046128 241 0.644
muscle cell proliferation GO:0033002 52 0.635
outflow tract morphogenesis GO:0003151 53 0.635
regulation of ion homeostasis GO:2000021 64 0.627
septum primum development GO:0003284 4 0.623
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.617
regulation of mitochondrial fission GO:0090140 3 0.615
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.614
canonical wnt signaling pathway GO:0060070 130 0.613
cellular component assembly involved in morphogenesis GO:0010927 139 0.608
purine ribonucleotide catabolic process GO:0009154 208 0.607
regulation of cation channel activity GO:2001257 22 0.604
regulation of renin secretion into blood stream GO:1900133 4 0.603
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 7 0.603
myotube cell development GO:0014904 60 0.599
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.597
regulation of heart growth GO:0060420 31 0.596
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.594
negative regulation of cell proliferation GO:0008285 296 0.589
endoplasmic reticulum to cytosol transport GO:1903513 12 0.585
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.585
nucleoside triphosphate metabolic process GO:0009141 230 0.581
organic cyclic compound catabolic process GO:1901361 295 0.581
regulation of nucleotide metabolic process GO:0006140 169 0.581
organelle assembly GO:0070925 177 0.580
regulation of atrial cardiac muscle cell membrane depolarization GO:0060371 5 0.579
heart growth GO:0060419 45 0.577
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.575
cellular lipid metabolic process GO:0044255 323 0.573
regulation of cardiac muscle tissue development GO:0055024 31 0.564
ion transmembrane transport GO:0034220 361 0.555
glycosyl compound metabolic process GO:1901657 246 0.544
lens morphogenesis in camera type eye GO:0002089 24 0.543
telencephalon development GO:0021537 186 0.541
positive regulation of growth GO:0045927 104 0.533
his purkinje system cell differentiation GO:0060932 2 0.526
regulation of ion transmembrane transport GO:0034765 119 0.516
apoptotic signaling pathway GO:0097190 306 0.515
skeletal muscle organ development GO:0060538 163 0.508
Mouse
regulation of organ growth GO:0046620 61 0.507
nucleoside monophosphate catabolic process GO:0009125 59 0.507
myotube differentiation GO:0014902 105 0.505
determination of left right symmetry GO:0007368 80 0.505
anatomical structure homeostasis GO:0060249 145 0.505
sensory organ morphogenesis GO:0090596 242 0.504
ventricular septum development GO:0003281 42 0.503
ribose phosphate metabolic process GO:0019693 291 0.501
cellular amine metabolic process GO:0044106 44 0.501
cell adhesion GO:0007155 329 0.500
positive regulation of striated muscle tissue development GO:0045844 31 0.496
cellular chemical homeostasis GO:0055082 215 0.496
single organismal cell cell adhesion GO:0016337 131 0.495
nucleobase containing small molecule metabolic process GO:0055086 352 0.495
skeletal muscle thin filament assembly GO:0030240 2 0.492
purine nucleoside monophosphate catabolic process GO:0009128 58 0.492
blastocyst formation GO:0001825 33 0.491
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.489
cardiac septum development GO:0003279 59 0.485
positive regulation of heart contraction GO:0045823 14 0.474
muscle filament sliding GO:0030049 1 0.472
cardiac muscle cell proliferation GO:0060038 31 0.471
locomotory behavior GO:0007626 195 0.466
regulation of ion transmembrane transporter activity GO:0032412 54 0.466
cation homeostasis GO:0055080 212 0.459
purine nucleoside catabolic process GO:0006152 205 0.457
nucleotide metabolic process GO:0009117 332 0.456
calcium ion transmembrane transport GO:0070588 85 0.452
cell communication by chemical coupling GO:0010643 2 0.450
stem cell development GO:0048864 219 0.446
clara cell differentiation GO:0060486 4 0.446
regulation of cardiac muscle cell action potential GO:0098901 1 0.446
purine ribonucleoside catabolic process GO:0046130 205 0.439
positive regulation of blood circulation GO:1903524 22 0.436
aromatic compound catabolic process GO:0019439 286 0.436
metal ion homeostasis GO:0055065 189 0.434
regulation of skeletal muscle contraction GO:0014819 3 0.425
skeletal myofibril assembly GO:0014866 4 0.421
nucleoside catabolic process GO:0009164 206 0.416
regulation of body fluid levels GO:0050878 162 0.415
stem cell differentiation GO:0048863 268 0.411
cell type specific apoptotic process GO:0097285 268 0.411
proepicardium development GO:0003342 2 0.409
cellular nitrogen compound catabolic process GO:0044270 280 0.409
bmp signaling pathway GO:0030509 93 0.407
atrioventricular node cell development GO:0060928 2 0.405
divalent inorganic cation transport GO:0072511 178 0.402
central nervous system neuron differentiation GO:0021953 162 0.398
nucleoside triphosphate catabolic process GO:0009143 205 0.397
cellular calcium ion homeostasis GO:0006874 119 0.397
inorganic ion transmembrane transport GO:0098660 234 0.394
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.393
purine nucleoside triphosphate catabolic process GO:0009146 203 0.393
mitral valve morphogenesis GO:0003183 4 0.392
calcium ion transport GO:0006816 159 0.391
aortic valve morphogenesis GO:0003180 4 0.388
digestive tract morphogenesis GO:0048546 147 0.387
axonogenesis GO:0007409 274 0.386
epithelial cell development GO:0002064 159 0.384
striated muscle adaptation GO:0014888 26 0.378
regulation of cardiac muscle tissue growth GO:0055021 26 0.378
amine metabolic process GO:0009308 45 0.375
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.371
septum transversum development GO:0003343 2 0.371
cerebral cortex development GO:0021987 86 0.371
ventricular septum morphogenesis GO:0060412 27 0.369
urogenital system development GO:0001655 261 0.368
regulation of wnt signaling pathway GO:0030111 123 0.366
negative regulation of cell development GO:0010721 169 0.363
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.362
primary neural tube formation GO:0014020 95 0.359
gas homeostasis GO:0033483 3 0.358
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.357
skeletal muscle cell differentiation GO:0035914 66 0.356
epithelial tube morphogenesis GO:0060562 303 0.355
pancreatic pp cell fate commitment GO:0003329 2 0.355
striated muscle cell proliferation GO:0014855 39 0.352
second messenger mediated signaling GO:0019932 73 0.350
detection of stimulus GO:0051606 84 0.349
tissue remodeling GO:0048771 102 0.349
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.345
cytosolic calcium ion transport GO:0060401 48 0.345
appendage morphogenesis GO:0035107 149 0.344
pallium development GO:0021543 120 0.336
cellular response to organic cyclic compound GO:0071407 87 0.329
cardiac pacemaker cell fate commitment GO:0060927 1 0.328
regulation of muscle tissue development GO:1901861 97 0.316
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.316
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.315
cell differentiation involved in embryonic placenta development GO:0060706 26 0.314
neuron apoptotic process GO:0051402 142 0.313
endodermal cell fate specification GO:0001714 4 0.312
hematopoietic progenitor cell differentiation GO:0002244 143 0.312
sinoatrial node cell differentiation GO:0060921 3 0.304
positive regulation of atpase activity GO:0032781 3 0.301
response to inorganic substance GO:0010035 96 0.299
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.298
megakaryocyte differentiation GO:0030219 26 0.298
olfactory bulb development GO:0021772 30 0.298
ribonucleoside triphosphate metabolic process GO:0009199 220 0.297
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.296
plasma cell differentiation GO:0002317 3 0.295
coronary vasculature development GO:0060976 12 0.294
negative regulation of apoptotic signaling pathway GO:2001234 104 0.292
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.290
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.285
pharynx development GO:0060465 1 0.282
tricuspid valve development GO:0003175 3 0.281
atrioventricular node cell fate commitment GO:0060929 1 0.280
limb development GO:0060173 166 0.276
actin myosin filament sliding GO:0033275 1 0.274
hematopoietic stem cell differentiation GO:0060218 8 0.274
regulation of membrane depolarization during action potential GO:0098902 1 0.271
regulation of cell adhesion GO:0030155 154 0.270
inorganic cation transmembrane transport GO:0098662 207 0.268
wnt signaling pathway GO:0016055 188 0.267
positive regulation of ion transmembrane transport GO:0034767 24 0.267
positive regulation of heart rate GO:0010460 10 0.267
relaxation of muscle GO:0090075 18 0.266
ribonucleoside monophosphate metabolic process GO:0009161 80 0.265
membrane depolarization during sa node cell action potential GO:0086046 2 0.265
appendage development GO:0048736 166 0.264
regulation of atpase activity GO:0043462 9 0.264
synaptic transmission GO:0007268 329 0.263
regionalization GO:0003002 337 0.262
cellular divalent inorganic cation homeostasis GO:0072503 127 0.261
regulation of cellular ketone metabolic process GO:0010565 66 0.257
t cell activation GO:0042110 289 0.255
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.253
hindbrain development GO:0030902 128 0.252
regulation of wound healing GO:0061041 40 0.251
response to muscle inactivity GO:0014870 4 0.251
regulation of ion transport GO:0043269 215 0.250
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.250
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.245
positive regulation of cardiac muscle contraction GO:0060452 2 0.245
astrocyte fate commitment GO:0060018 4 0.241
multicellular organismal signaling GO:0035637 91 0.241
angiogenesis GO:0001525 201 0.241
organophosphate catabolic process GO:0046434 232 0.239
cation transmembrane transport GO:0098655 266 0.236
sensory perception of light stimulus GO:0050953 54 0.236
cell cell signaling involved in cardiac conduction GO:0086019 6 0.233
regulation of calcium ion transmembrane transport GO:1903169 20 0.233
cation transport GO:0006812 399 0.232
regulation of apoptotic signaling pathway GO:2001233 197 0.232
sequestering of metal ion GO:0051238 19 0.231
neuroblast proliferation GO:0007405 49 0.231
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.229
regulation of neuron death GO:1901214 134 0.229
developmental induction GO:0031128 34 0.229
regulation of actin filament based movement GO:1903115 12 0.229
negative regulation of cellular amine metabolic process GO:0033239 1 0.225
directional locomotion GO:0033058 3 0.223
regulation of transmembrane transport GO:0034762 128 0.222
vagus nerve development GO:0021564 3 0.221
regulation of osteoblast differentiation GO:0045667 67 0.219
mesenchymal cell differentiation GO:0048762 107 0.219
cellular protein complex assembly GO:0043623 116 0.216
regulation of actin filament based process GO:0032970 99 0.216
branching morphogenesis of an epithelial tube GO:0048754 159 0.216
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.215
myeloid cell differentiation GO:0030099 233 0.215
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.214
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.213
cardiac atrium development GO:0003230 24 0.211
atp catabolic process GO:0006200 55 0.211
mitral valve development GO:0003174 4 0.210
embryonic epithelial tube formation GO:0001838 130 0.210
negative regulation of cell cycle GO:0045786 123 0.208
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.206
negative regulation of cardiac muscle tissue development GO:0055026 8 0.205
molting cycle GO:0042303 90 0.203
purkinje myocyte differentiation GO:0003168 1 0.202
sa node cell to atrial cardiac muscle cell communication GO:0086070 5 0.201
pancreatic pp cell differentiation GO:0003312 2 0.200
skin development GO:0043588 220 0.198
developmental maturation GO:0021700 193 0.197
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.197
positive regulation of epithelial cell proliferation GO:0050679 68 0.197
ossification GO:0001503 216 0.196
ventral spinal cord interneuron fate determination GO:0060580 1 0.196
tissue migration GO:0090130 68 0.195
adult behavior GO:0030534 135 0.193
blastocyst development GO:0001824 80 0.193
ribonucleoside metabolic process GO:0009119 245 0.193
regulation of striated muscle cell differentiation GO:0051153 81 0.192
alpha amino acid catabolic process GO:1901606 18 0.190
positive regulation of ryanodine sensitive calcium release channel activity GO:0060316 1 0.190
determination of heart left right asymmetry GO:0061371 48 0.186
heart valve development GO:0003170 23 0.180
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.178
bone development GO:0060348 120 0.176
single organism cell adhesion GO:0098602 156 0.176
response to oxidative stress GO:0006979 123 0.176
blood vessel morphogenesis GO:0048514 285 0.175
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.174
sinoatrial node cell development GO:0060931 3 0.172
regulation of heart rate by cardiac conduction GO:0086091 6 0.170
regulation of neuron apoptotic process GO:0043523 122 0.169
neural fold elevation formation GO:0021502 1 0.169
positive regulation of muscle tissue development GO:1901863 32 0.168
negative regulation of homeostatic process GO:0032845 71 0.167
kidney development GO:0001822 213 0.167
regulation of cardioblast differentiation GO:0051890 3 0.167
his purkinje system development GO:0003164 4 0.166
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.165
cellular amino acid metabolic process GO:0006520 103 0.164
neuron death GO:0070997 154 0.164
protein localization to organelle GO:0033365 185 0.164
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.164
adult locomotory behavior GO:0008344 91 0.163
transmembrane transport GO:0055085 412 0.162
purine nucleoside monophosphate metabolic process GO:0009126 81 0.161
positive regulation of cell development GO:0010720 237 0.161
regulation of mesenchymal cell proliferation GO:0010464 37 0.161
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.160
positive regulation of cardiac muscle tissue development GO:0055025 19 0.159
central nervous system morphogenesis GO:0021551 2 0.159
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.159
cellular response to organonitrogen compound GO:0071417 145 0.157
alpha amino acid metabolic process GO:1901605 59 0.157
myoblast differentiation GO:0045445 52 0.157
atrioventricular valve development GO:0003171 15 0.157
artery development GO:0060840 53 0.156
mesoderm formation GO:0001707 62 0.155
cellular homeostasis GO:0019725 240 0.155
dna metabolic process GO:0006259 303 0.155
response to organic cyclic compound GO:0014070 198 0.154
catecholamine metabolic process GO:0006584 30 0.153
cellular ion homeostasis GO:0006873 165 0.153
limb morphogenesis GO:0035108 149 0.152
leukocyte differentiation GO:0002521 342 0.151
digestive tract development GO:0048565 190 0.150
cardiac muscle tissue growth GO:0055017 37 0.150
anatomical structure maturation GO:0071695 49 0.150
membrane repolarization GO:0086009 7 0.149
lymphocyte differentiation GO:0030098 242 0.149
regulation of skeletal muscle fiber development GO:0048742 36 0.148
olfactory lobe development GO:0021988 32 0.148
hemangioblast cell differentiation GO:0060217 1 0.148
regulation of stem cell proliferation GO:0072091 78 0.148
globus pallidus development GO:0021759 2 0.147
regulation of membrane potential GO:0042391 192 0.146
regulation of blood pressure GO:0008217 93 0.145
response to hypoxia GO:0001666 58 0.144
organic hydroxy compound metabolic process GO:1901615 203 0.144
positive regulation of osteoblast differentiation GO:0045669 34 0.144
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.144
regulation of cellular component biogenesis GO:0044087 181 0.141
regulation of voltage gated calcium channel activity GO:1901385 4 0.141
lens development in camera type eye GO:0002088 62 0.141
atrial septum primum morphogenesis GO:0003289 3 0.139
calcium mediated signaling GO:0019722 46 0.138
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 0.138
divalent metal ion transport GO:0070838 172 0.137
divalent inorganic cation homeostasis GO:0072507 138 0.137
muscle cell cellular homeostasis GO:0046716 12 0.137
mesenchymal cell development GO:0014031 93 0.136
myeloid cell homeostasis GO:0002262 114 0.136
specification of organ identity GO:0010092 30 0.134
action potential GO:0001508 78 0.134
muscle hypertrophy GO:0014896 24 0.133
response to activity GO:0014823 13 0.132
telencephalon cell migration GO:0022029 55 0.132
endocardial cushion development GO:0003197 26 0.131
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.131
renal system development GO:0072001 225 0.131
ventricular cardiac muscle cell differentiation GO:0055012 17 0.130
positive regulation of mapk cascade GO:0043410 170 0.130
epithelial tube formation GO:0072175 130 0.130
regulation of myoblast differentiation GO:0045661 29 0.130
positive regulation of nucleoside metabolic process GO:0045979 91 0.129
regulation of cell cycle GO:0051726 281 0.128
regulation of cellular amine metabolic process GO:0033238 20 0.128
tongue development GO:0043586 18 0.128
positive regulation of calcium ion transport GO:0051928 27 0.128
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.127
platelet morphogenesis GO:0036344 13 0.127
cellular ketone metabolic process GO:0042180 84 0.127
cell proliferation involved in heart valve development GO:2000793 2 0.127
cellular response to growth factor stimulus GO:0071363 197 0.126
positive regulation of fat cell proliferation GO:0070346 1 0.126
negative regulation of nervous system development GO:0051961 156 0.125
sodium ion transport GO:0006814 73 0.125
megakaryocyte development GO:0035855 15 0.124
atrioventricular valve morphogenesis GO:0003181 13 0.124
wound healing GO:0042060 157 0.124
response to stimulus involved in regulation of muscle adaptation GO:0014874 6 0.123
atrioventricular node cell differentiation GO:0060922 2 0.123
striated muscle hypertrophy GO:0014897 24 0.121
cytoplasmic transport GO:0016482 234 0.121
mitochondrion distribution GO:0048311 4 0.121
response to organonitrogen compound GO:0010243 246 0.120
mesenchyme development GO:0060485 152 0.120
endodermal cell fate commitment GO:0001711 12 0.120
regulation of cardiac chamber formation GO:1901210 1 0.118
carboxylic acid catabolic process GO:0046395 51 0.118
response to denervation involved in regulation of muscle adaptation GO:0014894 4 0.118
regulation of transporter activity GO:0032409 57 0.118
oxygen homeostasis GO:0032364 2 0.118
negative regulation of cell migration GO:0030336 59 0.117
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.117
pancreatic a cell fate commitment GO:0003326 2 0.117
epidermis development GO:0008544 187 0.117
regulation of epithelial cell proliferation GO:0050678 141 0.117
lipid modification GO:0030258 65 0.116
embryonic limb morphogenesis GO:0030326 126 0.116
regulation of muscle cell apoptotic process GO:0010660 17 0.116
regulation of vasodilation GO:0042312 5 0.116
positive regulation of hydrolase activity GO:0051345 148 0.116
negative regulation of molecular function GO:0044092 258 0.115
positive regulation of nucleotide catabolic process GO:0030813 88 0.115
axon ensheathment GO:0008366 76 0.115
adrenergic receptor signaling pathway GO:0071875 13 0.115
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.115

Myl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.999
cardiovascular system disease DOID:1287 0 0.999
heart disease DOID:114 0 0.999
muscular disease DOID:0080000 0 0.999
musculoskeletal system disease DOID:17 0 0.999
muscle tissue disease DOID:66 0 0.999
myopathy DOID:423 0 0.998
cardiomyopathy DOID:0050700 0 0.998
intrinsic cardiomyopathy DOID:0060036 0 0.998
dilated cardiomyopathy DOID:12930 0 0.909
hypertrophic cardiomyopathy DOID:11984 0 0.886
muscular dystrophy DOID:9884 0 0.165
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.145
congenital heart disease DOID:1682 0 0.137
heart septal defect DOID:1681 0 0.137
ventricular septal defect DOID:1657 0 0.137