Mus musculus

0 known processes

Ctsj

cathepsin J

(Aliases: CATP,Ctsp,MGC117662,CatRLP)

Ctsj biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of microvillus organization GO:0032530 3 0.382
negative regulation of endothelial cell migration GO:0010596 4 0.222
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.209
regulation of microvillus assembly GO:0032534 3 0.187
regulation of transforming growth factor beta secretion GO:2001201 1 0.179
transforming growth factor beta secretion GO:0038044 1 0.174
regulation of interleukin 10 secretion GO:2001179 4 0.146
transmembrane transport GO:0055085 412 0.127
cation transport GO:0006812 399 0.105
macromolecule catabolic process GO:0009057 281 0.092
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.087
protein modification by small protein conjugation or removal GO:0070647 207 0.086
protein maturation GO:0051604 176 0.084
ion transmembrane transport GO:0034220 361 0.083
stem cell proliferation GO:0072089 117 0.082
cation transmembrane transport GO:0098655 266 0.077
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.075
regulation of hydrolase activity GO:0051336 246 0.071
protein catabolic process GO:0030163 221 0.071
Mouse
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.071
regulation of cell projection assembly GO:0060491 38 0.071
regulation of defense response GO:0031347 233 0.069
cellular amino acid metabolic process GO:0006520 103 0.069
interleukin 10 secretion GO:0072608 4 0.065
blood vessel morphogenesis GO:0048514 285 0.062
inorganic ion transmembrane transport GO:0098660 234 0.061
angiogenesis GO:0001525 201 0.061
muscle fiber development GO:0048747 76 0.061
inorganic cation transmembrane transport GO:0098662 207 0.060
muscle cell differentiation GO:0042692 261 0.059
regulation of body fluid levels GO:0050878 162 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.056
regulation of muscle tissue development GO:1901861 97 0.055
cytokine production GO:0001816 319 0.055
skeletal system development GO:0001501 356 0.055
regulation of cellular component biogenesis GO:0044087 181 0.055
protein processing GO:0016485 163 0.052
regulation of skeletal muscle fiber development GO:0048742 36 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
skeletal muscle fiber development GO:0048741 58 0.049
regulation of cell motility GO:2000145 236 0.049
cellular ketone metabolic process GO:0042180 84 0.046
response to organonitrogen compound GO:0010243 246 0.046
regulation of cytokine production GO:0001817 266 0.045
positive regulation of cytokine production GO:0001819 174 0.044
regulation of myotube differentiation GO:0010830 62 0.044
positive regulation of cell migration GO:0030335 109 0.043
regulation of protein maturation GO:1903317 96 0.042
immune effector process GO:0002252 321 0.042
regulation of vasculature development GO:1901342 88 0.042
negative regulation of molecular function GO:0044092 258 0.042
protein ubiquitination GO:0016567 171 0.042
muscle cell development GO:0055001 133 0.041
regulation of protein processing GO:0070613 96 0.041
protein modification by small protein conjugation GO:0032446 187 0.040
myotube cell development GO:0014904 60 0.040
synaptic transmission GO:0007268 329 0.040
regulation of membrane potential GO:0042391 192 0.040
blood coagulation GO:0007596 76 0.040
negative regulation of hydrolase activity GO:0051346 71 0.040
negative regulation of angiogenesis GO:0016525 25 0.039
sensory perception GO:0007600 245 0.039
mitochondrion organization GO:0007005 134 0.039
negative regulation of vasculature development GO:1901343 26 0.039
oxidation reduction process GO:0055114 342 0.038
regulation of transmembrane transport GO:0034762 128 0.038
regulation of angiogenesis GO:0045765 81 0.038
positive regulation of stem cell proliferation GO:2000648 59 0.037
multicellular organismal signaling GO:0035637 91 0.037
negative regulation of proteolysis GO:0045861 74 0.037
skeletal muscle organ development GO:0060538 163 0.037
anion transport GO:0006820 177 0.037
carnitine transport GO:0015879 3 0.035
cellular protein catabolic process GO:0044257 155 0.035
paramesonephric duct development GO:0061205 3 0.035
regulation of protein localization GO:0032880 231 0.034
striated muscle cell development GO:0055002 125 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
myotube differentiation GO:0014902 105 0.033
connective tissue development GO:0061448 179 0.033
regulation of cell activation GO:0050865 289 0.033
negative regulation of blood vessel morphogenesis GO:2000181 25 0.032
cell cell adhesion GO:0098609 41 0.032
response to peptide GO:1901652 136 0.032
regulation of striated muscle cell differentiation GO:0051153 81 0.032
ubiquitin dependent protein catabolic process GO:0006511 129 0.031
cellular macromolecule catabolic process GO:0044265 206 0.031
muscle tissue development GO:0060537 308 0.031
peptidyl amino acid modification GO:0018193 336 0.031
fertilization GO:0009566 127 0.031
cellular amine metabolic process GO:0044106 44 0.030
response to acid chemical GO:0001101 111 0.030
positive regulation of cell development GO:0010720 237 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.029
response to insulin GO:0032868 100 0.029
skin development GO:0043588 220 0.029
regulation of cell projection organization GO:0031344 206 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
regulation of ion transport GO:0043269 215 0.029
myoblast differentiation GO:0045445 52 0.028
spermatogenesis GO:0007283 284 0.028
anatomical structure homeostasis GO:0060249 145 0.028
striated muscle tissue development GO:0014706 293 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
regulation of transferase activity GO:0051338 263 0.028
negative regulation of muscle cell differentiation GO:0051148 33 0.028
amine metabolic process GO:0009308 45 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
negative regulation of cell cycle GO:0045786 123 0.027
Mouse
negative regulation of protein processing GO:0010955 79 0.027
wound healing GO:0042060 157 0.027
negative regulation of cell proliferation GO:0008285 296 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
regulation of myoblast differentiation GO:0045661 29 0.026
coagulation GO:0050817 78 0.026
regulation of cell cycle GO:0051726 281 0.026
Mouse
regulation of cell migration GO:0030334 219 0.026
cellular response to organic cyclic compound GO:0071407 87 0.026
response to nutrient levels GO:0031667 109 0.026
epithelium migration GO:0090132 63 0.026
locomotory behavior GO:0007626 195 0.026
positive regulation of nervous system development GO:0051962 221 0.026
cellular response to organonitrogen compound GO:0071417 145 0.025
response to organic cyclic compound GO:0014070 198 0.025
negative regulation of myoblast differentiation GO:0045662 18 0.025
response to light stimulus GO:0009416 135 0.024
sodium ion transport GO:0006814 73 0.024
cellular lipid metabolic process GO:0044255 323 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
response to growth factor GO:0070848 198 0.023
negative regulation of mitotic cell cycle GO:0045930 58 0.023
Mouse
purine containing compound metabolic process GO:0072521 311 0.022
proteasomal protein catabolic process GO:0010498 98 0.022
peptidyl tyrosine phosphorylation GO:0018108 143 0.022
sulfur compound metabolic process GO:0006790 100 0.022
action potential GO:0001508 78 0.022
negative regulation of response to wounding GO:1903035 77 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
carboxylic acid transport GO:0046942 100 0.022
regulation of mapk cascade GO:0043408 248 0.022
positive regulation of neuroblast proliferation GO:0002052 19 0.022
organic acid transport GO:0015849 101 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.021
stem cell differentiation GO:0048863 268 0.021
positive regulation of cell motility GO:2000147 116 0.021
response to peptide hormone GO:0043434 127 0.021
cell differentiation involved in embryonic placenta development GO:0060706 26 0.021
Mouse
positive regulation of epithelial cell migration GO:0010634 19 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
positive regulation of cell projection organization GO:0031346 95 0.021
lipid biosynthetic process GO:0008610 179 0.021
leukocyte differentiation GO:0002521 342 0.021
regulation of protein catabolic process GO:0042176 108 0.020
regulation of neuroblast proliferation GO:1902692 27 0.020
regulation of proteolysis GO:0030162 164 0.020
regulation of protein transport GO:0051223 163 0.020
regulation of neural precursor cell proliferation GO:2000177 70 0.020
regulation of stem cell proliferation GO:0072091 78 0.020
cell type specific apoptotic process GO:0097285 268 0.020
ear development GO:0043583 200 0.020
neuroblast proliferation GO:0007405 49 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
amino acid betaine transport GO:0015838 3 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
positive regulation of protein modification process GO:0031401 299 0.019
response to lipopolysaccharide GO:0032496 128 0.019
carnitine transmembrane transport GO:1902603 3 0.019
midgut development GO:0007494 4 0.019
regulation of organelle organization GO:0033043 289 0.019
regulation of neuron differentiation GO:0045664 281 0.019
cellular potassium ion transport GO:0071804 43 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
cell division GO:0051301 120 0.018
positive regulation of interleukin 8 production GO:0032757 2 0.018
nitrogen compound transport GO:0071705 271 0.018
calcium ion transport GO:0006816 159 0.018
neural precursor cell proliferation GO:0061351 121 0.018
blood circulation GO:0008015 195 0.018
tissue homeostasis GO:0001894 115 0.018
negative regulation of cell migration GO:0030336 59 0.018
negative regulation of endopeptidase activity GO:0010951 44 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
regulation of epithelial cell migration GO:0010632 35 0.017
cellular response to lipid GO:0071396 145 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
wnt signaling pathway GO:0016055 188 0.017
metanephric loop of henle development GO:0072236 4 0.017
oviduct development GO:0060066 3 0.017
negative regulation of cell motility GO:2000146 61 0.017
carbohydrate metabolic process GO:0005975 230 0.017
regulation of response to wounding GO:1903034 189 0.017
regionalization GO:0003002 337 0.017
amino acid transmembrane transport GO:0003333 37 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 4 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
negative regulation of peptidase activity GO:0010466 46 0.017
endothelial cell migration GO:0043542 44 0.016
nuclear division GO:0000280 158 0.016
palate development GO:0060021 76 0.016
positive regulation of endothelial cell migration GO:0010595 12 0.016
positive regulation of transferase activity GO:0051347 167 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
negative regulation of protein modification process GO:0031400 163 0.016
interferon gamma production GO:0032609 67 0.016
hemostasis GO:0007599 78 0.016
ensheathment of neurons GO:0007272 76 0.016
regulation of kinase activity GO:0043549 249 0.016
embryonic skeletal system development GO:0048706 120 0.016
negative regulation of cell development GO:0010721 169 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
cell adhesion GO:0007155 329 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
placenta development GO:0001890 140 0.015
Mouse
response to radiation GO:0009314 165 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
response to oxidative stress GO:0006979 123 0.015
gland development GO:0048732 330 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
regulation of wound healing GO:0061041 40 0.015
testosterone biosynthetic process GO:0061370 2 0.015
ossification GO:0001503 216 0.015
interspecies interaction between organisms GO:0044419 83 0.015
organic anion transport GO:0015711 137 0.015
nucleotide metabolic process GO:0009117 332 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
tissue remodeling GO:0048771 102 0.015
Mouse
cardiac muscle contraction GO:0060048 32 0.015
telencephalon development GO:0021537 186 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
cell substrate adhesion GO:0031589 130 0.015
lipid localization GO:0010876 126 0.015
positive regulation of angiogenesis GO:0045766 46 0.015
learning or memory GO:0007611 148 0.014
androgen biosynthetic process GO:0006702 4 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
axon ensheathment GO:0008366 76 0.014
male gamete generation GO:0048232 285 0.014
maintenance of location GO:0051235 89 0.014
polarity specification of proximal distal axis GO:0010085 2 0.014
detection of abiotic stimulus GO:0009582 60 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
intracellular protein transport GO:0006886 204 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
regulation of blood pressure GO:0008217 93 0.014
insulin like growth factor receptor signaling pathway GO:0048009 21 0.014
potassium ion transport GO:0006813 52 0.014
respiratory tube development GO:0030323 167 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
organonitrogen compound catabolic process GO:1901565 264 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
small molecule biosynthetic process GO:0044283 132 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
covalent chromatin modification GO:0016569 163 0.013
regulation of protein complex assembly GO:0043254 83 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
rhythmic process GO:0048511 174 0.013
regulation of secretion by cell GO:1903530 249 0.013
actin cytoskeleton organization GO:0030036 220 0.013
mitotic cell cycle process GO:1903047 159 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
cartilage development GO:0051216 140 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of cell cycle process GO:0010564 160 0.013
multi multicellular organism process GO:0044706 109 0.013
mitotic cell cycle GO:0000278 195 0.013
Mouse
binding of sperm to zona pellucida GO:0007339 34 0.013
circadian rhythm GO:0007623 114 0.013
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
alcohol metabolic process GO:0006066 116 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
monosaccharide metabolic process GO:0005996 106 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
steroid metabolic process GO:0008202 119 0.012
epithelial cell migration GO:0010631 63 0.012
regulation of innate immune response GO:0045088 91 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
multicellular organism growth GO:0035264 161 0.012
antimicrobial peptide biosynthetic process GO:0002777 2 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
response to estrogen GO:0043627 24 0.012
organelle fission GO:0048285 170 0.012
heart morphogenesis GO:0003007 178 0.012
interleukin 8 production GO:0032637 4 0.012
purine containing compound catabolic process GO:0072523 213 0.012
response to transforming growth factor beta GO:0071559 88 0.012
circulatory system process GO:0003013 197 0.012
developmental maturation GO:0021700 193 0.012
asymmetric stem cell division GO:0098722 3 0.012
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.012
response to drug GO:0042493 75 0.012
detection of external stimulus GO:0009581 61 0.012
gonad development GO:0008406 141 0.012
mapk cascade GO:0000165 281 0.012
single fertilization GO:0007338 82 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
protein kinase b signaling GO:0043491 74 0.012
positive regulation of immune effector process GO:0002699 107 0.012
regulation of cellular response to stress GO:0080135 159 0.012
regulation of blood coagulation GO:0030193 28 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
endomembrane system organization GO:0010256 147 0.011
cell cell junction organization GO:0045216 72 0.011
cytoplasmic transport GO:0016482 234 0.011
nucleotide catabolic process GO:0009166 217 0.011
extracellular structure organization GO:0043062 148 0.011
regulation of protein kinase activity GO:0045859 232 0.011
nuclear transport GO:0051169 139 0.011
positive regulation of thyroid hormone generation GO:2000611 2 0.011
limb development GO:0060173 166 0.011
purine nucleotide biosynthetic process GO:0006164 65 0.011
anion transmembrane transport GO:0098656 71 0.011
sensory organ morphogenesis GO:0090596 242 0.011
appendage morphogenesis GO:0035107 149 0.011
odontogenesis GO:0042476 78 0.011
regulation of viral transcription GO:0046782 3 0.011
protein localization to nucleus GO:0034504 121 0.011
viral gene expression GO:0019080 3 0.011
response to inorganic substance GO:0010035 96 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
response to oxygen levels GO:0070482 62 0.011
lymphocyte differentiation GO:0030098 242 0.011
peptide metabolic process GO:0006518 46 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
monocarboxylic acid transport GO:0015718 44 0.011
glucose metabolic process GO:0006006 92 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
negative regulation of viral transcription GO:0032897 3 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
cardiac ventricle development GO:0003231 83 0.011
negative regulation of protein maturation GO:1903318 79 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
organophosphate catabolic process GO:0046434 232 0.011
protein acylation GO:0043543 64 0.011
heterocycle catabolic process GO:0046700 280 0.011
regulation of protein kinase b signaling GO:0051896 56 0.010
regulation of ossification GO:0030278 112 0.010
female gonad development GO:0008585 71 0.010
cell junction organization GO:0034330 77 0.010
regulation of t cell differentiation GO:0045580 83 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
Mouse
glycoprotein metabolic process GO:0009100 116 0.010
neuronal action potential GO:0019228 54 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
protein secretion GO:0009306 111 0.010
myeloid cell homeostasis GO:0002262 114 0.010
leukocyte mediated immunity GO:0002443 174 0.010
regulation of transforming growth factor beta2 production GO:0032909 2 0.010
skeletal system morphogenesis GO:0048705 203 0.010
regulation of feeding behavior GO:0060259 3 0.010
amino acid transport GO:0006865 61 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.010
cellular amide metabolic process GO:0043603 58 0.010
positive regulation of secretion GO:0051047 130 0.010
negative regulation of epithelial cell migration GO:0010633 9 0.010
positive regulation of kinase activity GO:0033674 155 0.010
rna processing GO:0006396 105 0.010

Ctsj disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.040
retinal disease DOID:5679 0 0.033
sensory system disease DOID:0050155 0 0.033
disease of anatomical entity DOID:7 0 0.033
eye and adnexa disease DOID:1492 0 0.033
nervous system disease DOID:863 0 0.033
eye disease DOID:5614 0 0.033
acquired metabolic disease DOID:0060158 0 0.010