Mus musculus

0 known processes

Ctsk

cathepsin K

(Aliases: AI323530,Ms10q,catK,MMS10-Q)

Ctsk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue remodeling GO:0048771 102 0.700
Rat
tissue homeostasis GO:0001894 115 0.566
Rat
regulation of osteoclast differentiation GO:0045670 36 0.549
regulation of cell motility GO:2000145 236 0.538
anatomical structure homeostasis GO:0060249 145 0.531
Rat
osteoclast differentiation GO:0030316 62 0.514
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.497
extrinsic apoptotic signaling pathway GO:0097191 126 0.496
response to amino acid GO:0043200 37 0.485
positive regulation of programmed cell death GO:0043068 218 0.480
multicellular organismal homeostasis GO:0048871 164 0.454
Rat
positive regulation of apoptotic process GO:0043065 217 0.450
extracellular structure organization GO:0043062 148 0.433
Mouse
regulation of cell adhesion GO:0030155 154 0.395
regulation of tissue remodeling GO:0034103 38 0.395
ossification GO:0001503 216 0.349
Rat
negative regulation of phospholipase activity GO:0010519 4 0.335
regulation of cell migration GO:0030334 219 0.318
cellular response to amino acid stimulus GO:0071230 29 0.301
extracellular matrix organization GO:0030198 147 0.299
Mouse
myeloid leukocyte migration GO:0097529 57 0.291
cell adhesion GO:0007155 329 0.285
cell chemotaxis GO:0060326 81 0.281
organic acid transport GO:0015849 101 0.274
regulation of inflammatory response GO:0050727 147 0.262
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.246
regulation of mapk cascade GO:0043408 248 0.245
regulation of myeloid leukocyte differentiation GO:0002761 58 0.244
carboxylic acid transport GO:0046942 100 0.243
cellular response to acid chemical GO:0071229 68 0.237
organic anion transport GO:0015711 137 0.230
skeletal system development GO:0001501 356 0.229
skeletal system morphogenesis GO:0048705 203 0.226
positive regulation of cell death GO:0010942 224 0.225
negative regulation of hydrolase activity GO:0051346 71 0.222
response to acid chemical GO:0001101 111 0.215
regulation of bone resorption GO:0045124 24 0.212
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.203
regulation of response to wounding GO:1903034 189 0.198
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.198
bone resorption GO:0045453 38 0.193
Rat
connective tissue development GO:0061448 179 0.191
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.179
inflammatory response GO:0006954 244 0.179
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.179
response to organonitrogen compound GO:0010243 246 0.170
regulation of cell substrate adhesion GO:0010810 73 0.164
positive regulation of hydrolase activity GO:0051345 148 0.156
blood vessel morphogenesis GO:0048514 285 0.154
regulation of fatty acid transport GO:2000191 10 0.153
cellular divalent inorganic cation homeostasis GO:0072503 127 0.153
oxidation reduction process GO:0055114 342 0.148
endochondral bone morphogenesis GO:0060350 50 0.140
negative regulation of odontogenesis GO:0042483 3 0.137
cation transport GO:0006812 399 0.136
calcium ion homeostasis GO:0055074 127 0.135
positive regulation of cell motility GO:2000147 116 0.134
regulation of map kinase activity GO:0043405 120 0.133
cell substrate adhesion GO:0031589 130 0.131
bone development GO:0060348 120 0.129
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.127
myeloid cell differentiation GO:0030099 233 0.125
cellular response to organonitrogen compound GO:0071417 145 0.123
positive regulation of icosanoid secretion GO:0032305 7 0.123
positive regulation of inflammatory response GO:0050729 47 0.119
Mouse
negative regulation of cell adhesion GO:0007162 45 0.117
anion transport GO:0006820 177 0.117
small gtpase mediated signal transduction GO:0007264 97 0.116
cellular ketone metabolic process GO:0042180 84 0.116
synaptic transmission GO:0007268 329 0.111
cytokine mediated signaling pathway GO:0019221 115 0.110
regulation of leukocyte differentiation GO:1902105 159 0.110
odontogenesis of dentin containing tooth GO:0042475 66 0.108
cellular response to cytokine stimulus GO:0071345 189 0.105
regulation of bone remodeling GO:0046850 28 0.104
response to organic cyclic compound GO:0014070 198 0.103
trabecula formation GO:0060343 24 0.101
response to peptide hormone GO:0043434 127 0.100
positive regulation of thymocyte migration GO:2000412 2 0.100
renal system development GO:0072001 225 0.099
gland development GO:0048732 330 0.098
leukocyte chemotaxis GO:0030595 69 0.098
regulation of epithelial cell proliferation GO:0050678 141 0.097
Mouse
negative regulation of cell proliferation GO:0008285 296 0.095
Mouse
heart process GO:0003015 94 0.095
angiogenesis GO:0001525 201 0.093
bone trabecula morphogenesis GO:0061430 12 0.092
positive regulation of proteolysis GO:0045862 85 0.090
response to nutrient levels GO:0031667 109 0.090
regulation of erk1 and erk2 cascade GO:0070372 71 0.089
developmental maturation GO:0021700 193 0.089
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.088
divalent inorganic cation homeostasis GO:0072507 138 0.087
positive regulation of secretion GO:0051047 130 0.087
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.087
regulation of apoptotic signaling pathway GO:2001233 197 0.087
fatty acid transport GO:0015908 28 0.086
osteoclast development GO:0036035 9 0.085
regulation of myeloid cell differentiation GO:0045637 96 0.085
wound healing GO:0042060 157 0.085
lipid localization GO:0010876 126 0.084
stress activated protein kinase signaling cascade GO:0031098 81 0.084
circulatory system process GO:0003013 197 0.082
negative regulation of molecular function GO:0044092 258 0.082
cell matrix adhesion GO:0007160 68 0.081
positive regulation of cell migration GO:0030335 109 0.079
regulation of peptidase activity GO:0052547 96 0.079
proteoglycan metabolic process GO:0006029 38 0.078
ras protein signal transduction GO:0007265 77 0.078
anatomical structure maturation GO:0071695 49 0.078
Mouse
cellular amino acid metabolic process GO:0006520 103 0.078
digestive system development GO:0055123 200 0.078
positive regulation of chemotaxis GO:0050921 38 0.077
mononuclear cell migration GO:0071674 8 0.077
oocyte construction GO:0007308 2 0.077
metal ion homeostasis GO:0055065 189 0.075
leukocyte migration GO:0050900 124 0.074
cellular amine metabolic process GO:0044106 44 0.073
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.073
apoptotic signaling pathway GO:0097190 306 0.072
calcium ion transport GO:0006816 159 0.072
regulation of system process GO:0044057 200 0.072
negative regulation of cell substrate adhesion GO:0010812 16 0.072
erk1 and erk2 cascade GO:0070371 77 0.072
trabecula morphogenesis GO:0061383 40 0.071
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.070
regulation of cellular response to stress GO:0080135 159 0.070
regulation of blood coagulation GO:0030193 28 0.069
lung development GO:0030324 164 0.068
membrane organization GO:0061024 245 0.066
ion transmembrane transport GO:0034220 361 0.066
odontogenesis GO:0042476 78 0.065
innate immune response GO:0045087 157 0.064
response to transforming growth factor beta GO:0071559 88 0.064
regulation of cellular ketone metabolic process GO:0010565 66 0.064
replacement ossification GO:0036075 26 0.064
regulation of hydrolase activity GO:0051336 246 0.064
peptidyl amino acid modification GO:0018193 336 0.063
nitrogen compound transport GO:0071705 271 0.063
bmp signaling pathway GO:0030509 93 0.063
immune effector process GO:0002252 321 0.062
defense response to gram positive bacterium GO:0050830 50 0.062
regulation of stress activated mapk cascade GO:0032872 69 0.062
cellular homeostasis GO:0019725 240 0.061
limb morphogenesis GO:0035108 149 0.061
positive regulation of smooth muscle cell migration GO:0014911 4 0.061
positive regulation of cell adhesion GO:0045785 80 0.060
respiratory tube development GO:0030323 167 0.060
cartilage condensation GO:0001502 18 0.060
chemotaxis GO:0006935 247 0.059
cellular ion homeostasis GO:0006873 165 0.059
response to lipopolysaccharide GO:0032496 128 0.059
fibril organization GO:0097435 2 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
protein oligomerization GO:0051259 67 0.058
regulation of cell activation GO:0050865 289 0.057
regulation of acute inflammatory response GO:0002673 27 0.057
regulation of ossification GO:0030278 112 0.056
regulation of reactive oxygen species metabolic process GO:2000377 40 0.056
positive regulation of intracellular transport GO:0032388 70 0.055
bone trabecula formation GO:0060346 9 0.055
negative regulation of interleukin 13 production GO:0032696 2 0.055
face development GO:0060324 38 0.055
cellular response to bmp stimulus GO:0071773 14 0.055
striated muscle cell development GO:0055002 125 0.054
regulation of cysteine type endopeptidase activity GO:2000116 65 0.054
sensory perception GO:0007600 245 0.053
mammary gland morphogenesis GO:0060443 54 0.053
response to molecule of bacterial origin GO:0002237 143 0.053
activation of mapk activity GO:0000187 59 0.052
regulation of endopeptidase activity GO:0052548 89 0.052
positive regulation of response to wounding GO:1903036 66 0.051
Mouse
blood circulation GO:0008015 195 0.051
positive regulation of bone remodeling GO:0046852 13 0.050
protein processing GO:0016485 163 0.050
Mouse
wnt signaling pathway GO:0016055 188 0.050
monocarboxylic acid transport GO:0015718 44 0.050
cellular response to growth factor stimulus GO:0071363 197 0.050
growth plate cartilage development GO:0003417 14 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
positive regulation of protein phosphorylation GO:0001934 242 0.048
regulation of heart contraction GO:0008016 77 0.048
regulation of cytokine production GO:0001817 266 0.047
heart morphogenesis GO:0003007 178 0.047
c21 steroid hormone biosynthetic process GO:0006700 3 0.047
cellular lipid metabolic process GO:0044255 323 0.047
morphogenesis of a branching epithelium GO:0061138 193 0.047
regulation of protein transport GO:0051223 163 0.046
positive regulation of defense response GO:0031349 124 0.046
Mouse
protein maturation GO:0051604 176 0.046
Mouse
regulation of cardiac muscle hypertrophy GO:0010611 13 0.046
regulation of membrane potential GO:0042391 192 0.046
defense response to bacterium GO:0042742 119 0.046
chondrocyte development GO:0002063 24 0.046
embryonic skeletal system development GO:0048706 120 0.045
mesenchyme development GO:0060485 152 0.045
positive regulation of mapk cascade GO:0043410 170 0.045
regulation of canonical wnt signaling pathway GO:0060828 82 0.045
somatic cell dna recombination GO:0016444 51 0.044
multicellular organismal signaling GO:0035637 91 0.044
defense response to other organism GO:0098542 197 0.044
positive regulation of tissue remodeling GO:0034105 19 0.043
single organismal cell cell adhesion GO:0016337 131 0.043
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.043
regulation of ras protein signal transduction GO:0046578 114 0.043
rho protein signal transduction GO:0007266 32 0.043
response to extracellular stimulus GO:0009991 127 0.043
smooth muscle contraction GO:0006939 44 0.043
intrinsic apoptotic signaling pathway GO:0097193 132 0.042
endochondral bone growth GO:0003416 19 0.042
digestive tract development GO:0048565 190 0.042
cell growth involved in cardiac muscle cell development GO:0061049 3 0.042
zymogen activation GO:0031638 41 0.041
macromolecule catabolic process GO:0009057 281 0.041
Human Mouse
response to oxygen levels GO:0070482 62 0.041
positive regulation of homeostatic process GO:0032846 64 0.041
production of molecular mediator of immune response GO:0002440 103 0.041
regulation of lipid metabolic process GO:0019216 118 0.040
leukocyte differentiation GO:0002521 342 0.040
negative regulation of growth GO:0045926 99 0.040
negative regulation of phosphate metabolic process GO:0045936 184 0.040
positive regulation of cell activation GO:0050867 158 0.040
negative regulation of wnt signaling pathway GO:0030178 73 0.040
single organism cell adhesion GO:0098602 156 0.040
collagen fibril organization GO:0030199 32 0.039
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.039
regulation of body fluid levels GO:0050878 162 0.039
cellular metal ion homeostasis GO:0006875 151 0.039
striated muscle tissue development GO:0014706 293 0.038
response to decreased oxygen levels GO:0036293 59 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
oocyte axis specification GO:0007309 2 0.038
muscle cell development GO:0055001 133 0.038
regulation of proteolysis GO:0030162 164 0.038
molting cycle GO:0042303 90 0.038
Mouse
positive regulation of eosinophil migration GO:2000418 2 0.038
regulation of establishment of protein localization GO:0070201 181 0.038
regulation of chemotaxis GO:0050920 53 0.037
positive regulation of secretion by cell GO:1903532 114 0.037
digestive tract morphogenesis GO:0048546 147 0.037
extracellular fibril organization GO:0043206 2 0.037
cellular chemical homeostasis GO:0055082 215 0.037
energy derivation by oxidation of organic compounds GO:0015980 77 0.037
stress activated mapk cascade GO:0051403 80 0.036
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.036
urogenital system development GO:0001655 261 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
negative regulation of map kinase activity GO:0043407 34 0.036
muscle tissue development GO:0060537 308 0.036
interleukin 10 secretion GO:0072608 4 0.035
response to increased oxygen levels GO:0036296 2 0.035
fat cell differentiation GO:0045444 160 0.035
response to bmp GO:0071772 14 0.035
regulation of odontogenesis GO:0042481 18 0.035
response to peptide GO:1901652 136 0.034
cellular response to biotic stimulus GO:0071216 92 0.034
positive regulation of protein transport GO:0051222 93 0.034
response to inorganic substance GO:0010035 96 0.034
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.033
regulation of angiogenesis GO:0045765 81 0.033
regulation of bmp signaling pathway GO:0030510 60 0.033
cytosolic calcium ion homeostasis GO:0051480 70 0.033
response to hyperoxia GO:0055093 2 0.033
regulation of interleukin 10 secretion GO:2001179 4 0.033
osteoclast proliferation GO:0002158 4 0.033
negative regulation of bmp signaling pathway GO:0030514 35 0.033
dna metabolic process GO:0006259 303 0.032
divalent inorganic cation transport GO:0072511 178 0.032
kidney development GO:0001822 213 0.032
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.032
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
regulation of anion transport GO:0044070 27 0.032
positive regulation of protein secretion GO:0050714 52 0.032
biomineral tissue development GO:0031214 64 0.032
appendage development GO:0048736 166 0.031
response to interleukin 1 GO:0070555 11 0.031
hair follicle development GO:0001942 85 0.031
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.031
positive regulation of peptidase activity GO:0010952 49 0.031
appendage morphogenesis GO:0035107 149 0.031
neuronal action potential GO:0019228 54 0.031
action potential GO:0001508 78 0.031
response to hypoxia GO:0001666 58 0.031
positive regulation of vasoconstriction GO:0045907 4 0.031
cellular response to prostaglandin e stimulus GO:0071380 1 0.031
positive regulation of myotube differentiation GO:0010831 24 0.030
endothelial cell proliferation GO:0001935 27 0.030
vacuole organization GO:0007033 38 0.030
regulation of blood pressure GO:0008217 93 0.030
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
sphingolipid metabolic process GO:0006665 45 0.030
acid secretion GO:0046717 33 0.030
negative regulation of cell motility GO:2000146 61 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
epidermis development GO:0008544 187 0.029
Mouse
fatty acid metabolic process GO:0006631 121 0.029
negative regulation of gastrulation GO:2000542 3 0.029
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.029
regulation of protein secretion GO:0050708 82 0.029
icosanoid secretion GO:0032309 12 0.029
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.029
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.029
protein heterotrimerization GO:0070208 8 0.029
protein kinase b signaling GO:0043491 74 0.029
purine nucleotide metabolic process GO:0006163 302 0.028
bone remodeling GO:0046849 53 0.028
Rat
regulation of myotube differentiation GO:0010830 62 0.028
regulation of phospholipase a2 activity GO:0032429 3 0.028
long term synaptic potentiation GO:0060291 25 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
antibacterial peptide secretion GO:0002779 1 0.028
cellular response to inorganic substance GO:0071241 37 0.028
forebrain development GO:0030900 302 0.028
negative regulation of systemic arterial blood pressure GO:0003085 15 0.028
amino acid transport GO:0006865 61 0.028
regulation of aldosterone metabolic process GO:0032344 1 0.028
transmission of nerve impulse GO:0019226 76 0.028
mineralocorticoid biosynthetic process GO:0006705 1 0.028
engulfment of apoptotic cell GO:0043652 3 0.028
cellular response to oxidative stress GO:0034599 76 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
lateral line system development GO:0048925 1 0.027
glomerulus morphogenesis GO:0072102 10 0.027
interleukin 5 secretion GO:0072603 2 0.027
positive regulation of bone resorption GO:0045780 13 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
protein targeting GO:0006605 143 0.027
positive regulation of phospholipase activity GO:0010518 3 0.027
astrocyte cell migration GO:0043615 3 0.027
regulation of organ morphogenesis GO:2000027 144 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.027
response to oxidative stress GO:0006979 123 0.027
thymocyte migration GO:0072679 2 0.027
cartilage development GO:0051216 140 0.027
cellular response to lipopolysaccharide GO:0071222 77 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
positive regulation of monocyte differentiation GO:0045657 2 0.026
carbohydrate homeostasis GO:0033500 128 0.026
regulation of smooth muscle contraction GO:0006940 22 0.026
camp biosynthetic process GO:0006171 31 0.026
regulation of ion homeostasis GO:2000021 64 0.026
epithelial tube morphogenesis GO:0060562 303 0.026
cellular response to abiotic stimulus GO:0071214 56 0.026
positive regulation of protein kinase b signaling GO:0051897 32 0.026
activation of immune response GO:0002253 138 0.026
canonical wnt signaling pathway GO:0060070 130 0.026
fatty acid derivative transport GO:1901571 14 0.026
multicellular organismal catabolic process GO:0044243 7 0.026
Human
negative regulation of cell migration GO:0030336 59 0.026
negative regulation of ossification GO:0030279 49 0.026
regulation of odontogenesis of dentin containing tooth GO:0042487 11 0.026
mammary gland epithelium development GO:0061180 65 0.026
reactive oxygen species biosynthetic process GO:1903409 8 0.025
positive regulation of monocyte chemotaxis GO:0090026 2 0.025
antibacterial peptide biosynthetic process GO:0002780 2 0.025
cellular calcium ion homeostasis GO:0006874 119 0.025
regulation of eosinophil migration GO:2000416 2 0.025
positive regulation of lipid transport GO:0032370 22 0.025
endoderm formation GO:0001706 20 0.025
cellular response to tumor necrosis factor GO:0071356 21 0.025
negative regulation of angiogenesis GO:0016525 25 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.025
cellular response to peptide GO:1901653 92 0.025
peptide secretion GO:0002790 114 0.025
cytokine production GO:0001816 319 0.025
positive regulation of fat cell differentiation GO:0045600 32 0.025
negative regulation of interleukin 10 secretion GO:2001180 2 0.024
limb development GO:0060173 166 0.024
regulation of cytokine secretion GO:0050707 61 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
cellular response to prostaglandin stimulus GO:0071379 2 0.024
g protein coupled receptor internalization GO:0002031 3 0.024
lymphocyte migration GO:0072676 26 0.024
regulation of cytokine secretion involved in immune response GO:0002739 4 0.024
cell maturation GO:0048469 127 0.024
learning or memory GO:0007611 148 0.024
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
regulation of fat cell differentiation GO:0045598 81 0.024
peptidyl serine phosphorylation GO:0018105 74 0.024
circadian temperature homeostasis GO:0060086 2 0.024
developmental growth involved in morphogenesis GO:0060560 138 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.024
acute inflammatory response GO:0002526 41 0.024
regulation of lipase activity GO:0060191 15 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
t cell activation GO:0042110 289 0.023
aldosterone metabolic process GO:0032341 2 0.023
mapk cascade GO:0000165 281 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
ovarian follicle development GO:0001541 40 0.023
negative regulation of mapk cascade GO:0043409 65 0.023
immunoglobulin production GO:0002377 73 0.023
regulation of b cell activation GO:0050864 81 0.023
receptor mediated endocytosis GO:0006898 51 0.023
carbohydrate metabolic process GO:0005975 230 0.023
collagen metabolic process GO:0032963 17 0.023
Human
endomembrane system organization GO:0010256 147 0.023
myotube differentiation GO:0014902 105 0.022
lipid catabolic process GO:0016042 69 0.022
regulation of cytoplasmic transport GO:1903649 112 0.022
deltoid tuberosity development GO:0035993 3 0.022
purine containing compound biosynthetic process GO:0072522 70 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
membrane lipid biosynthetic process GO:0046467 32 0.022
regionalization GO:0003002 337 0.022
body morphogenesis GO:0010171 45 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
positive regulation of t cell activation GO:0050870 101 0.021
positive regulation of cell substrate adhesion GO:0010811 47 0.021
amine metabolic process GO:0009308 45 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
transmembrane transport GO:0055085 412 0.021
regulation of transferase activity GO:0051338 263 0.021
response to temperature stimulus GO:0009266 55 0.021
response to thyroid hormone GO:0097066 2 0.021
hormone secretion GO:0046879 128 0.021
cellular response to external stimulus GO:0071496 88 0.021
cellular response to organic cyclic compound GO:0071407 87 0.021
synaptic transmission glutamatergic GO:0035249 36 0.021
cation homeostasis GO:0055080 212 0.021
positive regulation of protein modification process GO:0031401 299 0.021
glycoprotein metabolic process GO:0009100 116 0.021
intracellular protein transport GO:0006886 204 0.021
epithelial to mesenchymal transition GO:0001837 47 0.021
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.021
regulation of defense response GO:0031347 233 0.021
Mouse
protein heterooligomerization GO:0051291 14 0.020
regulation of protein localization GO:0032880 231 0.020
mesenchymal cell differentiation GO:0048762 107 0.020
purine containing compound catabolic process GO:0072523 213 0.020
response to steroid hormone GO:0048545 56 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.020
peptide hormone secretion GO:0030072 109 0.020
regulation of p38mapk cascade GO:1900744 3 0.020
eosinophil migration GO:0072677 3 0.020
organelle localization GO:0051640 179 0.020
positive regulation of fatty acid oxidation GO:0046321 4 0.020
regulation of kinase activity GO:0043549 249 0.020
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.020
regulation of hormone levels GO:0010817 211 0.020
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.020
bone morphogenesis GO:0060349 78 0.020
regulation of peptide secretion GO:0002791 77 0.020
gastrulation GO:0007369 116 0.020
regulation of calcium ion transport into cytosol GO:0010522 31 0.020
amide transport GO:0042886 138 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
actin cytoskeleton organization GO:0030036 220 0.020
Mouse
monosaccharide transport GO:0015749 58 0.020
membrane depolarization GO:0051899 64 0.019
sulfur compound metabolic process GO:0006790 100 0.019
regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 1 0.019
regulation of vasculature development GO:1901342 88 0.019
granulocyte migration GO:0097530 43 0.019
l alpha amino acid transmembrane transport GO:1902475 23 0.019
positive regulation of map kinase activity GO:0043406 84 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.019
macrophage activation GO:0042116 27 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.019
mesenchymal cell development GO:0014031 93 0.019
monosaccharide metabolic process GO:0005996 106 0.019
regulation of muscle system process GO:0090257 80 0.019
lymphocyte costimulation GO:0031294 15 0.019
phosphatidylinositol mediated signaling GO:0048015 41 0.019
physiological cardiac muscle hypertrophy GO:0003301 3 0.019
small molecule biosynthetic process GO:0044283 132 0.019
response to radiation GO:0009314 165 0.019
regulation of macrophage chemotaxis GO:0010758 8 0.019
positive regulation of lymphocyte activation GO:0051251 140 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
germ cell development GO:0007281 185 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
multicellular organism growth GO:0035264 161 0.019
protein localization to membrane GO:0072657 108 0.018
regulation of biomineral tissue development GO:0070167 33 0.018
membrane lipid metabolic process GO:0006643 53 0.018
response to estrogen GO:0043627 24 0.018

Ctsk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.911
musculoskeletal system disease DOID:17 0 0.911
connective tissue disease DOID:65 0 0.911
bone remodeling disease DOID:0080005 0 0.490
bone disease DOID:0080001 0 0.490
osteosclerosis DOID:4254 0 0.490
disease of metabolism DOID:0014667 0 0.034
inherited metabolic disorder DOID:655 0 0.034
myopathy DOID:423 0 0.028
congenital muscular dystrophy DOID:0050557 0 0.028
muscular disease DOID:0080000 0 0.028
muscular dystrophy DOID:9884 0 0.028
muscle tissue disease DOID:66 0 0.028
bone development disease DOID:0080006 0 0.026
retinal disease DOID:5679 0 0.022
retinal degeneration DOID:8466 0 0.022
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022