Mus musculus

88 known processes

Ctsl

cathepsin L

(Aliases: nkt,Ctsl1,fs,1190035F06Rik,MEP)

Ctsl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of apoptotic signaling pathway GO:2001235 95 0.545
positive regulation of programmed cell death GO:0043068 218 0.542
male gamete generation GO:0048232 285 0.519
Rat
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.431
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.416
apoptotic signaling pathway GO:0097190 306 0.382
positive regulation of apoptotic process GO:0043065 217 0.374
cellular response to external stimulus GO:0071496 88 0.310
Rat
hair cycle phase GO:0044851 16 0.283
extrinsic apoptotic signaling pathway GO:0097191 126 0.262
response to organic cyclic compound GO:0014070 198 0.262
Rat
cellular macromolecule catabolic process GO:0044265 206 0.261
Mouse
cellular response to hormone stimulus GO:0032870 150 0.238
skin development GO:0043588 220 0.232
spermatogenesis GO:0007283 284 0.225
Rat
negative regulation of necrotic cell death GO:0060547 11 0.222
response to peptide GO:1901652 136 0.209
peptide metabolic process GO:0006518 46 0.209
autophagy GO:0006914 45 0.195
angiogenesis GO:0001525 201 0.195
protein processing GO:0016485 163 0.188
innate immune response GO:0045087 157 0.173
response to extracellular stimulus GO:0009991 127 0.170
Rat
male courtship behavior GO:0008049 2 0.170
amine metabolic process GO:0009308 45 0.169
striated muscle tissue development GO:0014706 293 0.164
transmission of nerve impulse GO:0019226 76 0.164
regulation of membrane potential GO:0042391 192 0.161
macromolecule catabolic process GO:0009057 281 0.152
Mouse
neuronal action potential GO:0019228 54 0.151
camera type eye development GO:0043010 266 0.149
anatomical structure maturation GO:0071695 49 0.149
multicellular organismal signaling GO:0035637 91 0.144
response to organonitrogen compound GO:0010243 246 0.141
necrotic cell death GO:0070265 30 0.137
protein catabolic process GO:0030163 221 0.136
Mouse
epidermis morphogenesis GO:0048730 33 0.130
cellular protein catabolic process GO:0044257 155 0.129
Mouse
muscle tissue development GO:0060537 308 0.129
hair cycle GO:0042633 90 0.126
regulation of blood pressure GO:0008217 93 0.125
positive regulation of cell death GO:0010942 224 0.121
maternal process involved in female pregnancy GO:0060135 32 0.120
glycoprotein biosynthetic process GO:0009101 89 0.119
urogenital system development GO:0001655 261 0.115
stem cell development GO:0048864 219 0.112
positive regulation of protein modification process GO:0031401 299 0.109
carbohydrate derivative biosynthetic process GO:1901137 183 0.108
liver development GO:0001889 66 0.105
circulatory system process GO:0003013 197 0.105
glycoprotein metabolic process GO:0009100 116 0.104
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.098
developmental growth involved in morphogenesis GO:0060560 138 0.097
triglyceride metabolic process GO:0006641 51 0.095
anagen GO:0042640 13 0.095
regulation of cytokine production GO:0001817 266 0.093
posttranscriptional regulation of gene expression GO:0010608 155 0.092
organonitrogen compound biosynthetic process GO:1901566 192 0.092
regulation of cellular ketone metabolic process GO:0010565 66 0.092
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.091
morphogenesis of a branching epithelium GO:0061138 193 0.090
homeostasis of number of cells GO:0048872 210 0.086
post embryonic hemopoiesis GO:0035166 4 0.086
biomineral tissue development GO:0031214 64 0.086
renal system development GO:0072001 225 0.085
establishment of protein localization to organelle GO:0072594 118 0.084
nucleotide metabolic process GO:0009117 332 0.084
skin morphogenesis GO:0043589 38 0.083
gland development GO:0048732 330 0.083
gonad development GO:0008406 141 0.082
Rat
glycerolipid metabolic process GO:0046486 122 0.082
response to peptide hormone GO:0043434 127 0.081
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.081
purine nucleoside metabolic process GO:0042278 241 0.080
regulation of inflammatory response GO:0050727 147 0.079
Mouse
molting cycle GO:0042303 90 0.079
biological phase GO:0044848 20 0.078
heart morphogenesis GO:0003007 178 0.075
response to oxidative stress GO:0006979 123 0.074
lung development GO:0030324 164 0.073
ensheathment of neurons GO:0007272 76 0.073
cytokine production GO:0001816 319 0.071
cellular ketone metabolic process GO:0042180 84 0.071
decidualization GO:0046697 10 0.069
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.068
regulation of epithelial cell proliferation GO:0050678 141 0.068
skeletal muscle organ development GO:0060538 163 0.067
cellular amine metabolic process GO:0044106 44 0.067
cellular lipid metabolic process GO:0044255 323 0.066
cellular ion homeostasis GO:0006873 165 0.066
multi multicellular organism process GO:0044706 109 0.065
regulation of neuron apoptotic process GO:0043523 122 0.065
cellular response to thyroid hormone stimulus GO:0097067 1 0.064
metal ion homeostasis GO:0055065 189 0.064
cellular amide metabolic process GO:0043603 58 0.063
respiratory tube development GO:0030323 167 0.062
regulation of protein stability GO:0031647 52 0.062
stem cell differentiation GO:0048863 268 0.062
myelination GO:0042552 74 0.062
regulation of cellular catabolic process GO:0031329 242 0.062
immune effector process GO:0002252 321 0.061
regulation of defense response GO:0031347 233 0.061
Mouse
lipid biosynthetic process GO:0008610 179 0.060
cellular nitrogen compound catabolic process GO:0044270 280 0.058
regulation of cellular amine metabolic process GO:0033238 20 0.058
hepaticobiliary system development GO:0061008 67 0.058
developmental maturation GO:0021700 193 0.057
blood vessel morphogenesis GO:0048514 285 0.057
regulation of hormone levels GO:0010817 211 0.056
t cell differentiation in thymus GO:0033077 77 0.056
multicellular organismal macromolecule metabolic process GO:0044259 19 0.056
phospholipid transfer to membrane GO:0006649 2 0.056
mitochondrion organization GO:0007005 134 0.055
regulation of peptidase activity GO:0052547 96 0.055
protein maturation GO:0051604 176 0.055
regulation of lymphocyte activation GO:0051249 240 0.054
axon ensheathment GO:0008366 76 0.053
male sex differentiation GO:0046661 109 0.053
Rat
regulation of angiotensin levels in blood GO:0002002 4 0.053
multicellular organismal catabolic process GO:0044243 7 0.053
regulation of blood vessel size GO:0050880 56 0.053
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.053
anion transport GO:0006820 177 0.052
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.052
regulation of protein transport GO:0051223 163 0.052
regulation of leukocyte differentiation GO:1902105 159 0.051
bone mineralization GO:0030282 54 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
response to interleukin 4 GO:0070670 23 0.050
cellular response to cytokine stimulus GO:0071345 189 0.049
aromatic compound catabolic process GO:0019439 286 0.049
cellular response to extracellular stimulus GO:0031668 81 0.048
Rat
dendrite development GO:0016358 115 0.048
negative regulation of molecular function GO:0044092 258 0.048
positive regulation of cellular amine metabolic process GO:0033240 5 0.048
positive regulation of defense response GO:0031349 124 0.048
Mouse
cellular metal ion homeostasis GO:0006875 151 0.047
regulation of necrotic cell death GO:0010939 13 0.047
organic hydroxy compound metabolic process GO:1901615 203 0.046
positive regulation of cell development GO:0010720 237 0.046
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.046
branching morphogenesis of an epithelial tube GO:0048754 159 0.045
respiratory system development GO:0060541 190 0.045
male gonad development GO:0008584 88 0.045
Rat
regulation of tube size GO:0035150 57 0.044
response to steroid hormone GO:0048545 56 0.044
Rat
regulation of kinase activity GO:0043549 249 0.044
heterocycle catabolic process GO:0046700 280 0.044
rna catabolic process GO:0006401 29 0.044
response to molecule of bacterial origin GO:0002237 143 0.044
mapk cascade GO:0000165 281 0.044
response to thyroid hormone GO:0097066 2 0.043
regulation of proteolysis GO:0030162 164 0.043
telencephalon development GO:0021537 186 0.042
immune response activating signal transduction GO:0002757 116 0.042
gliogenesis GO:0042063 141 0.042
nucleoside phosphate metabolic process GO:0006753 338 0.042
regulation of secretion GO:0051046 274 0.042
ribonucleoside catabolic process GO:0042454 206 0.042
cellular response to abiotic stimulus GO:0071214 56 0.042
iron ion homeostasis GO:0055072 36 0.042
positive regulation of cytokine production GO:0001819 174 0.042
action potential GO:0001508 78 0.041
cell adhesion GO:0007155 329 0.041
reactive oxygen species biosynthetic process GO:1903409 8 0.041
kidney morphogenesis GO:0060993 83 0.041
epithelial tube morphogenesis GO:0060562 303 0.040
positive regulation of innate immune response GO:0045089 80 0.040
growth involved in heart morphogenesis GO:0003241 4 0.040
nuclear import GO:0051170 95 0.040
protein modification by small protein conjugation GO:0032446 187 0.040
regulation of neuron differentiation GO:0045664 281 0.040
single organism cell adhesion GO:0098602 156 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
negative regulation of inflammatory response GO:0050728 61 0.039
response to endoplasmic reticulum stress GO:0034976 53 0.039
cellular homeostasis GO:0019725 240 0.039
regulation of systemic arterial blood pressure GO:0003073 61 0.039
cation transmembrane transport GO:0098655 266 0.039
t cell mediated immunity GO:0002456 50 0.039
response to tumor necrosis factor GO:0034612 26 0.038
inflammatory response GO:0006954 244 0.038
Mouse
tissue regeneration GO:0042246 22 0.038
sensory organ morphogenesis GO:0090596 242 0.038
cellular amino acid metabolic process GO:0006520 103 0.038
protein localization to organelle GO:0033365 185 0.038
multicellular organismal homeostasis GO:0048871 164 0.037
ossification GO:0001503 216 0.037
connective tissue development GO:0061448 179 0.037
histone h3 k9 dimethylation GO:0036123 4 0.037
regulation of response to wounding GO:1903034 189 0.036
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.036
regulation of mapk cascade GO:0043408 248 0.036
wnt signaling pathway GO:0016055 188 0.035
hair follicle development GO:0001942 85 0.035
organelle assembly GO:0070925 177 0.035
cation homeostasis GO:0055080 212 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
ear development GO:0043583 200 0.035
negative regulation of intracellular signal transduction GO:1902532 167 0.035
response to acid chemical GO:0001101 111 0.035
single organism nuclear import GO:1902593 95 0.034
ceramide biosynthetic process GO:0046513 20 0.034
negative regulation of t cell proliferation GO:0042130 38 0.034
positive regulation of immune effector process GO:0002699 107 0.033
keratinocyte differentiation GO:0030216 48 0.033
regulation of cell activation GO:0050865 289 0.033
regulation of protein localization GO:0032880 231 0.033
carbohydrate metabolic process GO:0005975 230 0.033
development of primary sexual characteristics GO:0045137 143 0.033
Rat
leukocyte differentiation GO:0002521 342 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of lymphocyte proliferation GO:0050670 117 0.033
positive regulation of lymphocyte activation GO:0051251 140 0.033
defense response to other organism GO:0098542 197 0.033
isoprenoid metabolic process GO:0006720 29 0.032
microtubule based process GO:0007017 236 0.032
hexose metabolic process GO:0019318 98 0.032
negative regulation of blood pressure GO:0045776 22 0.032
peptide transport GO:0015833 133 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
vascular process in circulatory system GO:0003018 62 0.032
pole plasm assembly GO:0007315 2 0.032
leukocyte homeostasis GO:0001776 79 0.032
skeletal system development GO:0001501 356 0.032
neutral lipid metabolic process GO:0006638 57 0.032
acylglycerol metabolic process GO:0006639 55 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.031
t cell activation GO:0042110 289 0.031
immune response regulating signaling pathway GO:0002764 125 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
chemotaxis GO:0006935 247 0.031
t cell differentiation GO:0030217 174 0.031
muscle cell differentiation GO:0042692 261 0.031
tissue remodeling GO:0048771 102 0.030
dna metabolic process GO:0006259 303 0.030
positive regulation of leukocyte differentiation GO:1902107 86 0.030
oxidation reduction process GO:0055114 342 0.030
spleen development GO:0048536 39 0.030
leukocyte mediated immunity GO:0002443 174 0.030
positive regulation of gene silencing by mirna GO:2000637 1 0.030
blood circulation GO:0008015 195 0.030
positive regulation of proteolysis GO:0045862 85 0.030
multicellular organismal metabolic process GO:0044236 28 0.030
morphogenesis of a branching structure GO:0001763 203 0.029
kidney development GO:0001822 213 0.029
fat soluble vitamin biosynthetic process GO:0042362 4 0.029
negative regulation of cell proliferation GO:0008285 296 0.029
regeneration GO:0031099 38 0.029
maintenance of location GO:0051235 89 0.029
sphingolipid biosynthetic process GO:0030148 26 0.029
positive regulation of cellular catabolic process GO:0031331 148 0.029
b cell activation GO:0042113 161 0.029
cellular response to inorganic substance GO:0071241 37 0.028
spermatid development GO:0007286 108 0.028
sequestering of metal ion GO:0051238 19 0.028
negative regulation of defense response GO:0031348 77 0.028
membrane lipid biosynthetic process GO:0046467 32 0.028
cellular chemical homeostasis GO:0055082 215 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.028
regulation of amyloid precursor protein biosynthetic process GO:0042984 3 0.028
transition metal ion homeostasis GO:0055076 54 0.028
synapse organization GO:0050808 125 0.028
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.028
protein kinase b signaling GO:0043491 74 0.028
positive regulation of posttranscriptional gene silencing GO:0060148 1 0.028
negative regulation of apoptotic signaling pathway GO:2001234 104 0.028
leukocyte migration GO:0050900 124 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.027
endomembrane system organization GO:0010256 147 0.027
skeletal system morphogenesis GO:0048705 203 0.027
positive regulation of map kinase activity GO:0043406 84 0.027
positive regulation of protein transport GO:0051222 93 0.027
protein glycosylation GO:0006486 55 0.027
regulation of removal of superoxide radicals GO:2000121 4 0.027
glial cell development GO:0021782 54 0.027
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.027
protein import into nucleus GO:0006606 95 0.027
cardiac chamber development GO:0003205 108 0.027
tissue homeostasis GO:0001894 115 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
regulation of secretion by cell GO:1903530 249 0.026
sulfur compound metabolic process GO:0006790 100 0.026
sensory perception GO:0007600 245 0.026
b cell differentiation GO:0030183 78 0.026
epidermis development GO:0008544 187 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
response to alcohol GO:0097305 48 0.026
vacuole organization GO:0007033 38 0.026
positive regulation of hydrolase activity GO:0051345 148 0.025
negative regulation of cytokine production GO:0001818 84 0.025
antigen processing and presentation GO:0019882 47 0.025
lung alveolus development GO:0048286 45 0.025
lipid transport GO:0006869 98 0.025
multi organism behavior GO:0051705 62 0.025
positive regulation of chemotaxis GO:0050921 38 0.025
dna recombination GO:0006310 92 0.025
response to reactive oxygen species GO:0000302 56 0.025
second messenger mediated signaling GO:0019932 73 0.025
nucleoside metabolic process GO:0009116 246 0.025
cardiac chamber morphogenesis GO:0003206 93 0.024
response to monosaccharide GO:0034284 67 0.024
Rat
organic anion transport GO:0015711 137 0.024
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.024
formation of radial glial scaffolds GO:0021943 4 0.024
purine containing compound biosynthetic process GO:0072522 70 0.024
positive regulation of secretion by cell GO:1903532 114 0.024
response to nutrient levels GO:0031667 109 0.024
Rat
regulation of protein sumoylation GO:0033233 4 0.024
regulation of hydrolase activity GO:0051336 246 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
neuron death GO:0070997 154 0.024
negative regulation of systemic arterial blood pressure GO:0003085 15 0.024
cytokine secretion GO:0050663 72 0.024
histone lysine methylation GO:0034968 50 0.024
muscle cell development GO:0055001 133 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.024
regulation of establishment of protein localization GO:0070201 181 0.023
small molecule biosynthetic process GO:0044283 132 0.023
positive regulation of phagocytosis engulfment GO:0060100 3 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
regulation of ossification GO:0030278 112 0.023
cholesterol metabolic process GO:0008203 56 0.023
mesonephros development GO:0001823 97 0.023
cell substrate adhesion GO:0031589 130 0.023
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.023
membrane organization GO:0061024 245 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
regulation of organ morphogenesis GO:2000027 144 0.022
cardiac ventricle development GO:0003231 83 0.022
transmembrane transport GO:0055085 412 0.022
regulation of body fluid levels GO:0050878 162 0.022
regulation of protein import into nucleus GO:0042306 52 0.022
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
organophosphate catabolic process GO:0046434 232 0.022
cell chemotaxis GO:0060326 81 0.022
regulation of protein catabolic process GO:0042176 108 0.022
regulation of angiotensin metabolic process GO:0060177 4 0.022
positive regulation of macroautophagy GO:0016239 3 0.022
regulation of cell growth GO:0001558 91 0.022
leukocyte mediated cytotoxicity GO:0001909 62 0.022
protein localization to nucleus GO:0034504 121 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.021
positive regulation of response to wounding GO:1903036 66 0.021
Mouse
ribose phosphate metabolic process GO:0019693 291 0.021
rho protein signal transduction GO:0007266 32 0.021
t cell proliferation GO:0042098 120 0.021
cellular response to lipid GO:0071396 145 0.021
hormone metabolic process GO:0042445 86 0.021
lipid localization GO:0010876 126 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
rna processing GO:0006396 105 0.020
ameboidal type cell migration GO:0001667 128 0.020
negative regulation of t cell activation GO:0050868 65 0.020
positive regulation of endopeptidase activity GO:0010950 43 0.020
calcium mediated signaling GO:0019722 46 0.020
spermatid differentiation GO:0048515 115 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
somatic stem cell maintenance GO:0035019 47 0.020
mrna metabolic process GO:0016071 84 0.020
anatomical structure homeostasis GO:0060249 145 0.020
sterol metabolic process GO:0016125 58 0.020
response to oxygen levels GO:0070482 62 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
carboxylic acid transport GO:0046942 100 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
negative regulation of neuron death GO:1901215 98 0.020
gene silencing by mirna GO:0035195 10 0.020
regulation of cell migration GO:0030334 219 0.020
cellularization GO:0007349 1 0.020
reactive nitrogen species metabolic process GO:2001057 0 0.019
protein acylation GO:0043543 64 0.019
embryonic hemopoiesis GO:0035162 23 0.019
membrane protein proteolysis GO:0033619 10 0.019
purine containing compound metabolic process GO:0072521 311 0.019
cell growth GO:0016049 130 0.019
extracellular structure organization GO:0043062 148 0.019
Mouse
lung morphogenesis GO:0060425 50 0.019
divalent metal ion transport GO:0070838 172 0.019
sequestering of calcium ion GO:0051208 18 0.019
neuron apoptotic process GO:0051402 142 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.019
organophosphate ester transport GO:0015748 28 0.019
regulation of neuron projection development GO:0010975 169 0.019
leukocyte proliferation GO:0070661 172 0.019
myeloid leukocyte migration GO:0097529 57 0.019
sphingolipid metabolic process GO:0006665 45 0.019
purine ribonucleotide biosynthetic process GO:0009152 59 0.019
negative regulation of ossification GO:0030279 49 0.019
regulation of cell projection organization GO:0031344 206 0.019
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
development of primary male sexual characteristics GO:0046546 88 0.018
Rat
positive regulation of growth GO:0045927 104 0.018
response to starvation GO:0042594 65 0.018
Rat
cellular component disassembly involved in execution phase of apoptosis GO:0006921 9 0.018
ribonucleoside monophosphate catabolic process GO:0009158 57 0.018
stem cell maintenance GO:0019827 130 0.018
lateral inhibition GO:0046331 1 0.018
striated muscle cell development GO:0055002 125 0.018
posttranscriptional gene silencing by rna GO:0035194 10 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of t cell mediated immunity GO:0002709 34 0.018
negative regulation of protein modification process GO:0031400 163 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of blood circulation GO:1903522 93 0.018
cellular response to epidermal growth factor stimulus GO:0071364 4 0.018
acylglycerol biosynthetic process GO:0046463 18 0.018
organ regeneration GO:0031100 2 0.018
cytokine biosynthetic process GO:0042089 68 0.018
glycosylation GO:0070085 62 0.018
monosaccharide biosynthetic process GO:0046364 44 0.018
endocytosis GO:0006897 168 0.018
morphogenesis of a polarized epithelium GO:0001738 37 0.018
regulation of lymphocyte differentiation GO:0045619 107 0.018
phospholipid transport GO:0015914 21 0.018
regulation of b cell activation GO:0050864 81 0.017
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
regulation of cellular response to stress GO:0080135 159 0.017
regulation of leukocyte proliferation GO:0070663 121 0.017
regulation of myeloid cell differentiation GO:0045637 96 0.017
vitamin metabolic process GO:0006766 23 0.017
cell type specific apoptotic process GO:0097285 268 0.017
wound healing GO:0042060 157 0.017
ion transmembrane transport GO:0034220 361 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
female sex differentiation GO:0046660 84 0.017
ureteric bud development GO:0001657 94 0.017
vasodilation GO:0042311 28 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
negative regulation of interleukin 2 production GO:0032703 8 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
negative regulation of cell motility GO:2000146 61 0.017
negative regulation of protein processing GO:0010955 79 0.017
positive regulation of protein sumoylation GO:0033235 3 0.017
cytokine metabolic process GO:0042107 71 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
apoptotic nuclear changes GO:0030262 9 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
smooth muscle tissue development GO:0048745 22 0.017
positive regulation of hormone metabolic process GO:0032352 3 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling GO:0003027 1 0.016
response to estrogen GO:0043627 24 0.016
positive regulation of cell migration GO:0030335 109 0.016
response to inorganic substance GO:0010035 96 0.016
regionalization GO:0003002 337 0.016
response to light stimulus GO:0009416 135 0.016
negative regulation of vasoconstriction GO:0045906 2 0.016
lymphocyte differentiation GO:0030098 242 0.016
regulation of neuron death GO:1901214 134 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
lymphocyte homeostasis GO:0002260 64 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
axonogenesis GO:0007409 274 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
cellular alcohol metabolic process GO:0044107 3 0.016
cell activation involved in immune response GO:0002263 126 0.016
regulation of myeloid leukocyte differentiation GO:0002761 58 0.016
glial cell differentiation GO:0010001 131 0.016
monosaccharide metabolic process GO:0005996 106 0.016
regulation of cytokine biosynthetic process GO:0042035 59 0.016
macromolecule glycosylation GO:0043413 55 0.016
release of sequestered calcium ion into cytosol GO:0051209 42 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of cellular component size GO:0032535 121 0.016
organic hydroxy compound transport GO:0015850 93 0.016

Ctsl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.473
inherited metabolic disorder DOID:655 0 0.473
disease of anatomical entity DOID:7 0 0.069
nervous system disease DOID:863 0 0.069
sensory system disease DOID:0050155 0 0.045
eye and adnexa disease DOID:1492 0 0.045
eye disease DOID:5614 0 0.045
musculoskeletal system disease DOID:17 0 0.043
lipid storage disease DOID:9455 0 0.038
lysosomal storage disease DOID:3211 0 0.038
integumentary system disease DOID:16 0 0.026
immune system disease DOID:2914 0 0.025
central nervous system disease DOID:331 0 0.023
brain disease DOID:936 0 0.023
neuropathy DOID:870 0 0.022
connective tissue disease DOID:65 0 0.020
neuromuscular disease DOID:440 0 0.019
charcot marie tooth disease DOID:10595 0 0.019
acquired metabolic disease DOID:0060158 0 0.018
sphingolipidosis DOID:1927 0 0.018
bone remodeling disease DOID:0080005 0 0.017
bone disease DOID:0080001 0 0.017