Mus musculus

39 known processes

Cts8

cathepsin 8

(Aliases: Epcs68,CTS2,Epcs70)

Cts8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 243 0.143
cation transport GO:0006812 399 0.092
ion transmembrane transport GO:0034220 361 0.090
transmembrane transport GO:0055085 412 0.090
cytokine production GO:0001816 319 0.086
cation transmembrane transport GO:0098655 266 0.085
regulation of microvillus organization GO:0032530 3 0.080
inorganic ion transmembrane transport GO:0098660 234 0.077
macromolecule catabolic process GO:0009057 281 0.076
regulation of microvillus assembly GO:0032534 3 0.063
amine metabolic process GO:0009308 45 0.061
organic hydroxy compound metabolic process GO:1901615 203 0.060
positive regulation of cellular amine metabolic process GO:0033240 5 0.060
positive regulation of cytokine production GO:0001819 174 0.059
angiogenesis GO:0001525 201 0.059
negative regulation of endothelial cell migration GO:0010596 4 0.058
regulation of defense response GO:0031347 233 0.057
blood vessel morphogenesis GO:0048514 285 0.053
regulation of cytokine production GO:0001817 266 0.052
nitrogen compound transport GO:0071705 271 0.051
inorganic cation transmembrane transport GO:0098662 207 0.050
positive regulation of protein modification process GO:0031401 299 0.050
anion transport GO:0006820 177 0.049
cellular amine metabolic process GO:0044106 44 0.049
regulation of angiogenesis GO:0045765 81 0.047
immune response regulating signaling pathway GO:0002764 125 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
regulation of cell cycle GO:0051726 281 0.045
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
positive regulation of transferase activity GO:0051347 167 0.044
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.044
protein catabolic process GO:0030163 221 0.044
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
regulation of vasculature development GO:1901342 88 0.043
locomotory behavior GO:0007626 195 0.043
anion transmembrane transport GO:0098656 71 0.043
carbohydrate derivative biosynthetic process GO:1901137 183 0.042
peptidyl amino acid modification GO:0018193 336 0.042
carbohydrate metabolic process GO:0005975 230 0.042
cellular amino acid metabolic process GO:0006520 103 0.041
oxidation reduction process GO:0055114 342 0.041
cellular homeostasis GO:0019725 240 0.041
purine nucleotide metabolic process GO:0006163 302 0.040
response to organonitrogen compound GO:0010243 246 0.040
regulation of cell migration GO:0030334 219 0.040
ribose phosphate metabolic process GO:0019693 291 0.039
positive regulation of cell migration GO:0030335 109 0.039
visual perception GO:0007601 52 0.039
cellular ketone metabolic process GO:0042180 84 0.039
sensory perception of light stimulus GO:0050953 54 0.039
lipid biosynthetic process GO:0008610 179 0.038
regulation of cell motility GO:2000145 236 0.038
purine containing compound metabolic process GO:0072521 311 0.038
regulation of secretion by cell GO:1903530 249 0.038
cellular chemical homeostasis GO:0055082 215 0.038
immune effector process GO:0002252 321 0.037
regulation of ion transport GO:0043269 215 0.036
immune response activating signal transduction GO:0002757 116 0.036
regulation of cell activation GO:0050865 289 0.036
regulation of transferase activity GO:0051338 263 0.036
regulation of protein localization GO:0032880 231 0.036
positive regulation of angiogenesis GO:0045766 46 0.035
innate immune response GO:0045087 157 0.034
muscle cell differentiation GO:0042692 261 0.033
positive regulation of ion transport GO:0043270 65 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.032
regulation of secretion GO:0051046 274 0.031
camera type eye development GO:0043010 266 0.031
activation of immune response GO:0002253 138 0.031
cellular macromolecule catabolic process GO:0044265 206 0.031
striated muscle tissue development GO:0014706 293 0.031
organic cyclic compound catabolic process GO:1901361 295 0.030
positive regulation of cell motility GO:2000147 116 0.030
nucleotide metabolic process GO:0009117 332 0.029
mapk cascade GO:0000165 281 0.029
defense response to bacterium GO:0042742 119 0.029
fertilization GO:0009566 127 0.029
ribonucleotide metabolic process GO:0009259 291 0.028
regulation of membrane potential GO:0042391 192 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.027
cytoplasmic transport GO:0016482 234 0.027
leukocyte mediated immunity GO:0002443 174 0.027
multicellular organismal homeostasis GO:0048871 164 0.027
multicellular organismal signaling GO:0035637 91 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
regulation of homeostatic process GO:0032844 182 0.026
regulation of lymphocyte proliferation GO:0050670 117 0.026
conditioned taste aversion GO:0001661 4 0.026
regulation of response to drug GO:2001023 2 0.026
positive regulation of cell development GO:0010720 237 0.025
positive regulation of nervous system development GO:0051962 221 0.025
positive regulation of kinase activity GO:0033674 155 0.025
germ cell development GO:0007281 185 0.025
tissue remodeling GO:0048771 102 0.025
sensory perception GO:0007600 245 0.024
axonogenesis GO:0007409 274 0.024
maintenance of location GO:0051235 89 0.024
circulatory system process GO:0003013 197 0.024
positive regulation of defense response GO:0031349 124 0.024
response to organic cyclic compound GO:0014070 198 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
ameboidal type cell migration GO:0001667 128 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of establishment of protein localization GO:0070201 181 0.023
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.023
exocytosis GO:0006887 121 0.023
retina development in camera type eye GO:0060041 119 0.023
leukocyte differentiation GO:0002521 342 0.023
negative regulation of molecular function GO:0044092 258 0.023
regulation of feeding behavior GO:0060259 3 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
regulation of t cell activation GO:0050863 170 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
cellular lipid metabolic process GO:0044255 323 0.022
protein maturation GO:0051604 176 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
regulation of protein transport GO:0051223 163 0.022
aromatic compound catabolic process GO:0019439 286 0.022
regulation of organelle organization GO:0033043 289 0.021
blood circulation GO:0008015 195 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
mesenchymal cell development GO:0014031 93 0.021
response to peptide hormone GO:0043434 127 0.021
multi multicellular organism process GO:0044706 109 0.021
peptide secretion GO:0002790 114 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
negative regulation of cell cycle GO:0045786 123 0.021
Mouse
purine containing compound biosynthetic process GO:0072522 70 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
muscle tissue development GO:0060537 308 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
response to inorganic substance GO:0010035 96 0.021
t cell activation GO:0042110 289 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
forebrain development GO:0030900 302 0.020
nucleotide biosynthetic process GO:0009165 78 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
negative regulation of immune system process GO:0002683 209 0.020
regulation of innate immune response GO:0045088 91 0.020
spermatogenesis GO:0007283 284 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
organic anion transport GO:0015711 137 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
pallium development GO:0021543 120 0.019
fat cell differentiation GO:0045444 160 0.019
response to radiation GO:0009314 165 0.019
ribose phosphate biosynthetic process GO:0046390 59 0.019
transforming growth factor beta secretion GO:0038044 1 0.019
cellular response to organic cyclic compound GO:0071407 87 0.019
sequestering of metal ion GO:0051238 19 0.019
regulation of striated muscle cell differentiation GO:0051153 81 0.019
negative regulation of angiogenesis GO:0016525 25 0.019
cyclic purine nucleotide metabolic process GO:0052652 43 0.019
cell type specific apoptotic process GO:0097285 268 0.018
anatomical structure homeostasis GO:0060249 145 0.018
response to lipopolysaccharide GO:0032496 128 0.018
single fertilization GO:0007338 82 0.018
male gamete generation GO:0048232 285 0.018
regulation of muscle tissue development GO:1901861 97 0.018
chloride transport GO:0006821 32 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
positive regulation of innate immune response GO:0045089 80 0.018
defense response to other organism GO:0098542 197 0.018
response to light stimulus GO:0009416 135 0.018
regulation of protein catabolic process GO:0042176 108 0.018
sequestering of calcium ion GO:0051208 18 0.018
dna metabolic process GO:0006259 303 0.017
regulation of protein kinase activity GO:0045859 232 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
purine ribonucleotide biosynthetic process GO:0009152 59 0.017
rhythmic process GO:0048511 174 0.017
peptide hormone secretion GO:0030072 109 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
inorganic anion transmembrane transport GO:0098661 29 0.017
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.017
metal ion homeostasis GO:0055065 189 0.017
palate development GO:0060021 76 0.017
positive regulation of secretion GO:0051047 130 0.017
cation homeostasis GO:0055080 212 0.017
tissue migration GO:0090130 68 0.017
regulation of neurotransmitter transport GO:0051588 35 0.017
cell adhesion GO:0007155 329 0.017
regulation of metal ion transport GO:0010959 106 0.017
lymphocyte proliferation GO:0046651 164 0.017
negative regulation of growth GO:0045926 99 0.017
response to drug GO:0042493 75 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
negative regulation of vasculature development GO:1901343 26 0.016
glycoprotein metabolic process GO:0009100 116 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
sodium ion transmembrane transport GO:0035725 49 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
response to peptide GO:1901652 136 0.016
response to acid chemical GO:0001101 111 0.016
neural precursor cell proliferation GO:0061351 121 0.016
detection of stimulus GO:0051606 84 0.016
regulation of kinase activity GO:0043549 249 0.016
organic acid transport GO:0015849 101 0.016
protein processing GO:0016485 163 0.016
cyclic nucleotide metabolic process GO:0009187 59 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.016
negative regulation of t cell activation GO:0050868 65 0.016
cyclic nucleotide biosynthetic process GO:0009190 44 0.015
regulation of protein maturation GO:1903317 96 0.015
negative regulation of defense response GO:0031348 77 0.015
response to extracellular stimulus GO:0009991 127 0.015
synaptic transmission GO:0007268 329 0.015
regulation of hydrolase activity GO:0051336 246 0.015
potassium ion transmembrane transport GO:0071805 43 0.015
regulation of neuron differentiation GO:0045664 281 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.015
telencephalon development GO:0021537 186 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
regulation of blood pressure GO:0008217 93 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of mapk cascade GO:0043408 248 0.015
cellular response to lipid GO:0071396 145 0.015
embryonic skeletal system development GO:0048706 120 0.015
regulation of t cell proliferation GO:0042129 92 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
skeletal muscle organ development GO:0060538 163 0.014
negative regulation of secretion GO:0051048 61 0.014
leukocyte proliferation GO:0070661 172 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
organic hydroxy compound transport GO:0015850 93 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
regulation of myotube differentiation GO:0010830 62 0.014
sodium ion transport GO:0006814 73 0.014
apoptotic signaling pathway GO:0097190 306 0.014
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.014
norepinephrine transport GO:0015874 2 0.014
regulation of leukocyte proliferation GO:0070663 121 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
response to oxidative stress GO:0006979 123 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
regulation of binding GO:0051098 111 0.014
negative regulation of secretion by cell GO:1903531 54 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
regulation of hormone levels GO:0010817 211 0.014
learning or memory GO:0007611 148 0.014
sulfur compound metabolic process GO:0006790 100 0.014
skeletal system morphogenesis GO:0048705 203 0.014
divalent metal ion transport GO:0070838 172 0.014
tube closure GO:0060606 91 0.014
amide transport GO:0042886 138 0.014
actin filament based movement GO:0030048 23 0.014
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.014
regulation of multi organism process GO:0043900 111 0.013
protein ubiquitination GO:0016567 171 0.013
single organism cell adhesion GO:0098602 156 0.013
sulfur compound transport GO:0072348 9 0.013
heart contraction GO:0060047 93 0.013
regulation of stem cell proliferation GO:0072091 78 0.013
regulation of ion homeostasis GO:2000021 64 0.013
neuron migration GO:0001764 122 0.013
glucose homeostasis GO:0042593 128 0.013
cellular protein catabolic process GO:0044257 155 0.013
negative regulation of t cell proliferation GO:0042130 38 0.013
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.013
positive regulation of neural precursor cell proliferation GO:2000179 42 0.013
striated muscle cell development GO:0055002 125 0.013
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.013
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.013
small molecule biosynthetic process GO:0044283 132 0.013
cellular ion homeostasis GO:0006873 165 0.013
developmental maturation GO:0021700 193 0.013
leukocyte migration GO:0050900 124 0.013
steroid metabolic process GO:0008202 119 0.013
cell activation involved in immune response GO:0002263 126 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
negative regulation of lymphocyte activation GO:0051250 91 0.013
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.013
epithelium migration GO:0090132 63 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
positive regulation of stem cell proliferation GO:2000648 59 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
alpha beta t cell activation GO:0046631 91 0.012
camp biosynthetic process GO:0006171 31 0.012
negative regulation of immune effector process GO:0002698 55 0.012
regionalization GO:0003002 337 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
protein secretion GO:0009306 111 0.012
neural tube formation GO:0001841 108 0.012
cognition GO:0050890 149 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
homeostasis of number of cells GO:0048872 210 0.012
l alpha amino acid transmembrane transport GO:1902475 23 0.012
peptide transport GO:0015833 133 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of transforming growth factor beta secretion GO:2001201 1 0.012
calcium ion transport GO:0006816 159 0.012
regulation of muscle system process GO:0090257 80 0.012
intracellular protein transport GO:0006886 204 0.012
small molecule catabolic process GO:0044282 71 0.012
t cell receptor signaling pathway GO:0050852 46 0.012
regulation of transmembrane transport GO:0034762 128 0.012
nucleotide catabolic process GO:0009166 217 0.012
multi organism behavior GO:0051705 62 0.012
physiological cardiac muscle hypertrophy GO:0003301 3 0.012
phenol containing compound metabolic process GO:0018958 60 0.012
somatotropin secreting cell differentiation GO:0060126 4 0.012
regulation of camp metabolic process GO:0030814 30 0.012
tissue homeostasis GO:0001894 115 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
cellular response to acid chemical GO:0071229 68 0.012
cellular response to external stimulus GO:0071496 88 0.012
gland development GO:0048732 330 0.012
dephosphorylation GO:0016311 129 0.012
cell maturation GO:0048469 127 0.012
negative regulation of homeostatic process GO:0032845 71 0.012
membrane hyperpolarization GO:0060081 21 0.012
activation of adenylate cyclase activity GO:0007190 4 0.012
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.012
circadian rhythm GO:0007623 114 0.012
myeloid cell differentiation GO:0030099 233 0.012
adult behavior GO:0030534 135 0.012
oocyte axis specification GO:0007309 2 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
endocytosis GO:0006897 168 0.012
regulation of response to wounding GO:1903034 189 0.012
regulation of proteolysis GO:0030162 164 0.012
t cell proliferation GO:0042098 120 0.011
positive regulation of immune effector process GO:0002699 107 0.011
multicellular organismal response to stress GO:0033555 62 0.011
lymphocyte differentiation GO:0030098 242 0.011
carbohydrate transport GO:0008643 62 0.011
neuron apoptotic process GO:0051402 142 0.011
regulation of system process GO:0044057 200 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
stem cell proliferation GO:0072089 117 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
mesodermal cell migration GO:0008078 4 0.011
ear development GO:0043583 200 0.011
negative regulation of neuron death GO:1901215 98 0.011
organophosphate catabolic process GO:0046434 232 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
chloride transmembrane transport GO:1902476 24 0.011
camp metabolic process GO:0046058 40 0.011
extracellular matrix organization GO:0030198 147 0.011
monosaccharide metabolic process GO:0005996 106 0.011
hormone metabolic process GO:0042445 86 0.011
isoprenoid metabolic process GO:0006720 29 0.011
potassium ion transport GO:0006813 52 0.011
heterocycle catabolic process GO:0046700 280 0.011
negative regulation of lymphocyte proliferation GO:0050672 45 0.011
positive regulation of cell activation GO:0050867 158 0.011
mitotic cell cycle GO:0000278 195 0.011
Mouse
negative regulation of multi organism process GO:0043901 68 0.011
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
cell growth GO:0016049 130 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
lung development GO:0030324 164 0.010
b cell activation GO:0042113 161 0.010
connective tissue development GO:0061448 179 0.010
negative regulation of leukocyte proliferation GO:0070664 46 0.010
feeding behavior GO:0007631 62 0.010
viral gene expression GO:0019080 3 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
cerebral cortex development GO:0021987 86 0.010
protein localization to organelle GO:0033365 185 0.010
ras protein signal transduction GO:0007265 77 0.010
epithelial cell migration GO:0010631 63 0.010
negative regulation of blood vessel morphogenesis GO:2000181 25 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
regulation of action potential GO:0098900 4 0.010
cellular response to ammonium ion GO:0071242 2 0.010
organic acid biosynthetic process GO:0016053 86 0.010
response to monosaccharide GO:0034284 67 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
inner ear receptor cell differentiation GO:0060113 61 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
dopamine metabolic process GO:0042417 23 0.010
regulation of cell projection assembly GO:0060491 38 0.010
mechanoreceptor differentiation GO:0042490 67 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
multicellular organism growth GO:0035264 161 0.010
nucleoside metabolic process GO:0009116 246 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
energy reserve metabolic process GO:0006112 39 0.010
interleukin 10 secretion GO:0072608 4 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010

Cts8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.012
disease of metabolism DOID:0014667 0 0.012