Mus musculus

0 known processes

Trim60

tripartite motif-containing 60

(Aliases: Rnf33,2czf45)

Trim60 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound catabolic process GO:0019439 286 0.077
ribonucleotide catabolic process GO:0009261 208 0.073
purine nucleotide metabolic process GO:0006163 302 0.072
nucleoside triphosphate catabolic process GO:0009143 205 0.071
organonitrogen compound catabolic process GO:1901565 264 0.071
immune effector process GO:0002252 321 0.070
Mouse
heterocycle catabolic process GO:0046700 280 0.066
purine nucleotide catabolic process GO:0006195 211 0.065
positive regulation of protein modification process GO:0031401 299 0.058
macromolecule catabolic process GO:0009057 281 0.055
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.055
microtubule based process GO:0007017 236 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.054
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.053
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
nucleotide catabolic process GO:0009166 217 0.047
purine ribonucleoside catabolic process GO:0046130 205 0.046
muscle cell differentiation GO:0042692 261 0.045
innate immune response GO:0045087 157 0.044
Mouse
purine containing compound metabolic process GO:0072521 311 0.044
nucleoside metabolic process GO:0009116 246 0.043
nucleotide metabolic process GO:0009117 332 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.040
glycosyl compound catabolic process GO:1901658 206 0.039
regulation of hydrolase activity GO:0051336 246 0.039
blood vessel morphogenesis GO:0048514 285 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
purine nucleoside metabolic process GO:0042278 241 0.038
neural tube development GO:0021915 160 0.037
nucleoside triphosphate metabolic process GO:0009141 230 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
cellular protein complex assembly GO:0043623 116 0.036
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.036
purine nucleoside catabolic process GO:0006152 205 0.035
regulation of reactive oxygen species metabolic process GO:2000377 40 0.034
Mouse
purine containing compound catabolic process GO:0072523 213 0.034
regulation of vasculature development GO:1901342 88 0.034
ribonucleoside catabolic process GO:0042454 206 0.033
mitotic cell cycle process GO:1903047 159 0.033
ribonucleoside metabolic process GO:0009119 245 0.032
regulation of angiogenesis GO:0045765 81 0.032
positive regulation of hydrolase activity GO:0051345 148 0.032
regulation of epithelial cell proliferation GO:0050678 141 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
regulation of membrane potential GO:0042391 192 0.031
positive regulation of protein kinase activity GO:0045860 144 0.031
regulation of protein kinase activity GO:0045859 232 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
ras protein signal transduction GO:0007265 77 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
regulation of purine nucleotide catabolic process GO:0033121 122 0.030
ribonucleotide metabolic process GO:0009259 291 0.029
sensory perception GO:0007600 245 0.029
regulation of nucleoside metabolic process GO:0009118 130 0.028
action potential GO:0001508 78 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
nucleoside catabolic process GO:0009164 206 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
skin development GO:0043588 220 0.027
defense response to other organism GO:0098542 197 0.026
Mouse
glycosyl compound metabolic process GO:1901657 246 0.026
microtubule cytoskeleton organization GO:0000226 157 0.025
cellular amino acid metabolic process GO:0006520 103 0.025
placenta development GO:0001890 140 0.024
ion transmembrane transport GO:0034220 361 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
Mouse
mapk cascade GO:0000165 281 0.023
sensory perception of smell GO:0007608 26 0.023
spindle assembly involved in mitosis GO:0090307 4 0.023
transmission of nerve impulse GO:0019226 76 0.023
forebrain development GO:0030900 302 0.023
positive regulation of protein transport GO:0051222 93 0.023
angiogenesis GO:0001525 201 0.023
response to light stimulus GO:0009416 135 0.022
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.022
Mouse
sensory perception of chemical stimulus GO:0007606 51 0.022
regulation of cellular component biogenesis GO:0044087 181 0.021
Mouse
gtp metabolic process GO:0046039 144 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
positive regulation of cell death GO:0010942 224 0.021
circulatory system process GO:0003013 197 0.021
fat cell differentiation GO:0045444 160 0.021
multi multicellular organism process GO:0044706 109 0.021
regulation of innate immune response GO:0045088 91 0.021
Mouse
tube closure GO:0060606 91 0.020
gland development GO:0048732 330 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
Mouse
endocytosis GO:0006897 168 0.020
multicellular organismal signaling GO:0035637 91 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
Mouse
transmembrane transport GO:0055085 412 0.020
amine metabolic process GO:0009308 45 0.019
regulation of mapk cascade GO:0043408 248 0.019
positive regulation of gtp catabolic process GO:0033126 85 0.019
regionalization GO:0003002 337 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
protein targeting GO:0006605 143 0.019
kidney development GO:0001822 213 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
jnk cascade GO:0007254 72 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
response to radiation GO:0009314 165 0.019
pallium development GO:0021543 120 0.018
organelle assembly GO:0070925 177 0.018
regulation of multi organism process GO:0043900 111 0.018
Mouse
cytokine production GO:0001816 319 0.018
Mouse
cellular amine metabolic process GO:0044106 44 0.018
cell adhesion GO:0007155 329 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.018
protein catabolic process GO:0030163 221 0.018
Mouse
response to organonitrogen compound GO:0010243 246 0.018
learning GO:0007612 98 0.018
regulation of interleukin 6 production GO:0032675 55 0.018
Mouse
defense response to bacterium GO:0042742 119 0.018
positive regulation of viral genome replication GO:0045070 2 0.018
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.018
neuronal action potential GO:0019228 54 0.018
peptidyl amino acid modification GO:0018193 336 0.018
regulation of transferase activity GO:0051338 263 0.018
negative regulation of cell development GO:0010721 169 0.017
Mouse
axonogenesis GO:0007409 274 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
dephosphorylation GO:0016311 129 0.017
positive regulation of epithelial cell proliferation GO:0050679 68 0.017
rhythmic process GO:0048511 174 0.017
wound healing GO:0042060 157 0.017
synaptic transmission involved in micturition GO:0060084 3 0.017
regulation of organelle organization GO:0033043 289 0.017
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
inflammatory response GO:0006954 244 0.017
respiratory system development GO:0060541 190 0.016
chemotaxis GO:0006935 247 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
Mouse
positive regulation of transferase activity GO:0051347 167 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
epithelial cell proliferation GO:0050673 174 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
acetate ester transport GO:1901374 2 0.016
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.016
Mouse
neuron apoptotic process GO:0051402 142 0.016
epidermis development GO:0008544 187 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
protein polyubiquitination GO:0000209 33 0.016
Mouse
positive regulation of gtpase activity GO:0043547 85 0.016
regulation of viral transcription GO:0046782 3 0.015
Mouse
regulation of neuron death GO:1901214 134 0.015
regulation of protein catabolic process GO:0042176 108 0.015
Mouse
single fertilization GO:0007338 82 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
cell growth GO:0016049 130 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
neuron death GO:0070997 154 0.015
intracellular protein transport GO:0006886 204 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
positive regulation of ras gtpase activity GO:0032320 65 0.015
negative regulation of response to wounding GO:1903035 77 0.015
multicellular organism growth GO:0035264 161 0.015
glycoprotein metabolic process GO:0009100 116 0.015
multi organism behavior GO:0051705 62 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
lateral inhibition GO:0046331 1 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
regulation of peptidase activity GO:0052547 96 0.015
viral transcription GO:0019083 3 0.014
Mouse
negative regulation of cellular component organization GO:0051129 194 0.014
Mouse
positive regulation of apoptotic process GO:0043065 217 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
organophosphate catabolic process GO:0046434 232 0.014
developmental maturation GO:0021700 193 0.014
regulation of response to wounding GO:1903034 189 0.014
synapse assembly GO:0007416 56 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
positive regulation of viral entry into host cell GO:0046598 3 0.014
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.014
negative regulation of immune system process GO:0002683 209 0.014
Mouse
organ growth GO:0035265 117 0.014
cation transmembrane transport GO:0098655 266 0.014
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
regulation of cell activation GO:0050865 289 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
regulation of inflammatory response GO:0050727 147 0.013
regulation of defense response GO:0031347 233 0.013
Mouse
positive regulation of catecholamine secretion GO:0033605 2 0.013
organelle localization GO:0051640 179 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
actin polymerization or depolymerization GO:0008154 54 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
anion transport GO:0006820 177 0.013
nitrogen compound transport GO:0071705 271 0.013
negative regulation of multi organism process GO:0043901 68 0.013
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
regulation of feeding behavior GO:0060259 3 0.013
protein polymerization GO:0051258 57 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
primary neural tube formation GO:0014020 95 0.013
endomembrane system organization GO:0010256 147 0.012
negative regulation of viral transcription GO:0032897 3 0.012
Mouse
regulation of action potential GO:0098900 4 0.012
oocyte differentiation GO:0009994 35 0.012
carbohydrate metabolic process GO:0005975 230 0.012
nuclear division GO:0000280 158 0.012
protein maturation GO:0051604 176 0.012
immune response activating signal transduction GO:0002757 116 0.012
Mouse
muscle system process GO:0003012 141 0.012
regulation of cellular component size GO:0032535 121 0.012
Mouse
asymmetric stem cell division GO:0098722 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
ensheathment of neurons GO:0007272 76 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
mitotic cell cycle GO:0000278 195 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
negative regulation of defense response GO:0031348 77 0.012
Mouse
positive regulation of kinase activity GO:0033674 155 0.012
mechanoreceptor differentiation GO:0042490 67 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
camera type eye development GO:0043010 266 0.012
synapse organization GO:0050808 125 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
extracellular matrix organization GO:0030198 147 0.012
digestive system development GO:0055123 200 0.012
asymmetric neuroblast division GO:0055059 1 0.012
regulation of reproductive process GO:2000241 66 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
regulation of cytokine production GO:0001817 266 0.012
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.012
positive regulation of dopamine secretion GO:0033603 2 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
stress activated protein kinase signaling cascade GO:0031098 81 0.011
extracellular structure organization GO:0043062 148 0.011
membrane organization GO:0061024 245 0.011
regulation of protein complex assembly GO:0043254 83 0.011
Mouse
striated muscle tissue development GO:0014706 293 0.011
cilium assembly GO:0042384 81 0.011
positive regulation of angiogenesis GO:0045766 46 0.011
regulation of map kinase activity GO:0043405 120 0.011
male gamete generation GO:0048232 285 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
heart morphogenesis GO:0003007 178 0.011
protein localization to organelle GO:0033365 185 0.011
epithelial cell development GO:0002064 159 0.011
adult behavior GO:0030534 135 0.011
protein ubiquitination GO:0016567 171 0.011
Mouse
leukocyte proliferation GO:0070661 172 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
fertilization GO:0009566 127 0.011
establishment of organelle localization GO:0051656 122 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
cardiac muscle tissue development GO:0048738 130 0.011
interspecies interaction between organisms GO:0044419 83 0.011
Mouse
leukocyte apoptotic process GO:0071887 71 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
regulation of kinase activity GO:0043549 249 0.011
cation transport GO:0006812 399 0.011
skeletal system development GO:0001501 356 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
regulation of cell migration GO:0030334 219 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
microtubule based transport GO:0010970 50 0.011
cilium morphogenesis GO:0060271 102 0.011
gonad development GO:0008406 141 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
leukocyte differentiation GO:0002521 342 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
neuron projection extension GO:1990138 64 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of gtp catabolic process GO:0033124 113 0.010
molting cycle GO:0042303 90 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
Mouse
regulation of ossification GO:0030278 112 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
Mouse
establishment of protein localization to organelle GO:0072594 118 0.010
acetylcholine transport GO:0015870 2 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of protein transport GO:0051223 163 0.010
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.010
regulation of protein processing GO:0070613 96 0.010
neuron migration GO:0001764 122 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
Mouse
neural tube patterning GO:0021532 43 0.010
tumor necrosis factor production GO:0032640 50 0.010
Mouse
cytoplasmic transport GO:0016482 234 0.010

Trim60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028