Mus musculus

0 known processes

Trim61

tripartite motif-containing 61

(Aliases: 2czf61,E330039K03Rik,Rnf35,AU018704,C85201)

Trim61 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
interleukin 10 secretion GO:0072608 4 0.188
positive regulation of transforming growth factor beta secretion GO:2001203 1 0.144
transforming growth factor beta secretion GO:0038044 1 0.132
ion transmembrane transport GO:0034220 361 0.130
anion transport GO:0006820 177 0.113
regulation of transforming growth factor beta secretion GO:2001201 1 0.103
fertilization GO:0009566 127 0.084
male gamete generation GO:0048232 285 0.084
transmembrane transport GO:0055085 412 0.082
stem cell proliferation GO:0072089 117 0.079
single fertilization GO:0007338 82 0.075
forebrain development GO:0030900 302 0.075
oxidation reduction process GO:0055114 342 0.072
sensory perception of sound GO:0007605 97 0.072
cellular lipid metabolic process GO:0044255 323 0.069
spermatogenesis GO:0007283 284 0.065
protein maturation GO:0051604 176 0.065
learning or memory GO:0007611 148 0.060
response to organonitrogen compound GO:0010243 246 0.057
gland development GO:0048732 330 0.056
aromatic compound catabolic process GO:0019439 286 0.056
nitrogen compound transport GO:0071705 271 0.055
regulation of cytokine production GO:0001817 266 0.055
Mouse
positive regulation of cell death GO:0010942 224 0.054
locomotory behavior GO:0007626 195 0.052
apoptotic signaling pathway GO:0097190 306 0.051
inorganic ion transmembrane transport GO:0098660 234 0.051
negative regulation of cell proliferation GO:0008285 296 0.050
negative regulation of immune system process GO:0002683 209 0.050
Mouse
protein localization to organelle GO:0033365 185 0.050
blastocyst development GO:0001824 80 0.047
muscle cell differentiation GO:0042692 261 0.046
positive regulation of angiogenesis GO:0045766 46 0.046
organonitrogen compound biosynthetic process GO:1901566 192 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
divalent inorganic cation transport GO:0072511 178 0.045
regulation of membrane potential GO:0042391 192 0.045
protein processing GO:0016485 163 0.045
ameboidal type cell migration GO:0001667 128 0.044
reactive oxygen species metabolic process GO:0072593 84 0.044
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.043
sensory perception GO:0007600 245 0.042
innate immune response GO:0045087 157 0.042
Mouse
cognition GO:0050890 149 0.042
carboxylic acid transport GO:0046942 100 0.040
negative regulation of nervous system development GO:0051961 156 0.039
Mouse
placenta development GO:0001890 140 0.039
circadian rhythm GO:0007623 114 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
organic anion transport GO:0015711 137 0.038
immune effector process GO:0002252 321 0.038
Mouse
protein catabolic process GO:0030163 221 0.038
Mouse
muscle contraction GO:0006936 101 0.037
negative regulation of response to wounding GO:1903035 77 0.036
calcium ion transport GO:0006816 159 0.036
b cell activation GO:0042113 161 0.036
negative regulation of cell development GO:0010721 169 0.035
Mouse
regulation of response to wounding GO:1903034 189 0.035
membrane organization GO:0061024 245 0.035
macromolecule catabolic process GO:0009057 281 0.034
Mouse
camera type eye development GO:0043010 266 0.034
cellular ion homeostasis GO:0006873 165 0.034
cell adhesion GO:0007155 329 0.034
lymphocyte differentiation GO:0030098 242 0.034
blood circulation GO:0008015 195 0.033
muscle tissue development GO:0060537 308 0.033
regulation of interleukin 10 secretion GO:2001179 4 0.033
spermatid development GO:0007286 108 0.033
sensory perception of mechanical stimulus GO:0050954 107 0.032
heart contraction GO:0060047 93 0.032
sensory perception of light stimulus GO:0050953 54 0.032
neuron apoptotic process GO:0051402 142 0.032
reactive nitrogen species metabolic process GO:2001057 0 0.031
cytokine production GO:0001816 319 0.031
Mouse
regulation of neuron differentiation GO:0045664 281 0.030
divalent metal ion transport GO:0070838 172 0.030
purine nucleotide biosynthetic process GO:0006164 65 0.030
neuronal action potential GO:0019228 54 0.030
purine containing compound metabolic process GO:0072521 311 0.030
endocytosis GO:0006897 168 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
Mouse
regulation of multi organism process GO:0043900 111 0.029
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.028
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.028
regulation of transferase activity GO:0051338 263 0.028
negative regulation of neuron apoptotic process GO:0043524 92 0.028
tissue migration GO:0090130 68 0.027
sperm egg recognition GO:0035036 37 0.027
rhythmic process GO:0048511 174 0.027
carbohydrate metabolic process GO:0005975 230 0.026
circulatory system process GO:0003013 197 0.026
epithelial tube morphogenesis GO:0060562 303 0.026
cellular homeostasis GO:0019725 240 0.026
cell type specific apoptotic process GO:0097285 268 0.025
regulation of lipid metabolic process GO:0019216 118 0.025
circadian sleep wake cycle rem sleep GO:0042747 1 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
zymogen activation GO:0031638 41 0.024
positive regulation of transferase activity GO:0051347 167 0.024
regulation of secretion GO:0051046 274 0.024
nucleotide metabolic process GO:0009117 332 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
striated muscle contraction GO:0006941 45 0.024
visual perception GO:0007601 52 0.024
amine metabolic process GO:0009308 45 0.024
positive regulation of apoptotic signaling pathway GO:2001235 95 0.024
maintenance of location GO:0051235 89 0.023
regulation of angiogenesis GO:0045765 81 0.023
regulation of circadian sleep wake cycle GO:0042749 3 0.023
multicellular organism growth GO:0035264 161 0.023
muscle tissue morphogenesis GO:0060415 53 0.023
epithelium migration GO:0090132 63 0.023
sensory system development GO:0048880 3 0.023
epithelial cell migration GO:0010631 63 0.023
second messenger mediated signaling GO:0019932 73 0.023
cation transmembrane transport GO:0098655 266 0.022
positive regulation of cell development GO:0010720 237 0.022
wound healing GO:0042060 157 0.022
angiogenesis GO:0001525 201 0.022
small molecule biosynthetic process GO:0044283 132 0.022
cation transport GO:0006812 399 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.021
myotube differentiation GO:0014902 105 0.021
regulation of feeding behavior GO:0060259 3 0.021
spermatid differentiation GO:0048515 115 0.021
negative regulation of cell activation GO:0050866 111 0.021
cardiac ventricle morphogenesis GO:0003208 50 0.021
regulation of secretion by cell GO:1903530 249 0.021
dna metabolic process GO:0006259 303 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
Mouse
positive regulation of programmed cell death GO:0043068 218 0.020
protein oligomerization GO:0051259 67 0.020
c21 steroid hormone biosynthetic process GO:0006700 3 0.020
multicellular organismal signaling GO:0035637 91 0.020
dephosphorylation GO:0016311 129 0.020
negative regulation of cell projection organization GO:0031345 56 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
sa node cell action potential GO:0086015 4 0.020
regulation of transmembrane transport GO:0034762 128 0.019
organic hydroxy compound biosynthetic process GO:1901617 77 0.019
neuron death GO:0070997 154 0.019
neuromuscular process GO:0050905 99 0.019
purine containing compound biosynthetic process GO:0072522 70 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
regionalization GO:0003002 337 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
homeostasis of number of cells GO:0048872 210 0.019
Mouse
ribonucleoside metabolic process GO:0009119 245 0.019
respiratory system development GO:0060541 190 0.019
meiotic cell cycle GO:0051321 122 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
muscle system process GO:0003012 141 0.018
regulation of innate immune response GO:0045088 91 0.018
Mouse
immune response regulating signaling pathway GO:0002764 125 0.018
Mouse
heterocycle catabolic process GO:0046700 280 0.018
compound eye development GO:0048749 1 0.018
response to light stimulus GO:0009416 135 0.018
negative regulation of multi organism process GO:0043901 68 0.018
Mouse
axon ensheathment GO:0008366 76 0.018
neural precursor cell proliferation GO:0061351 121 0.018
meiotic nuclear division GO:0007126 115 0.018
regulation of system process GO:0044057 200 0.018
blood vessel morphogenesis GO:0048514 285 0.018
calcium ion transmembrane transport GO:0070588 85 0.018
tube formation GO:0035148 140 0.017
myelination GO:0042552 74 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
Mouse
neural tube formation GO:0001841 108 0.017
calcium mediated signaling GO:0019722 46 0.017
cilium morphogenesis GO:0060271 102 0.017
regulation of protein complex assembly GO:0043254 83 0.017
Mouse
regulation of heart contraction GO:0008016 77 0.017
response to lipopolysaccharide GO:0032496 128 0.017
negative regulation of neuron differentiation GO:0045665 101 0.017
regulation of cell projection organization GO:0031344 206 0.017
regulation of cell migration GO:0030334 219 0.017
regulation of muscle system process GO:0090257 80 0.017
cardiac ventricle development GO:0003231 83 0.017
regulation of cellular amine metabolic process GO:0033238 20 0.017
action potential GO:0001508 78 0.017
regulation of neural precursor cell proliferation GO:2000177 70 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
methylation GO:0032259 134 0.016
organelle fission GO:0048285 170 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
nuclear transport GO:0051169 139 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of blood circulation GO:1903522 93 0.016
endomembrane system organization GO:0010256 147 0.016
mapk cascade GO:0000165 281 0.016
axonogenesis GO:0007409 274 0.016
fear response GO:0042596 33 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
nucleoside metabolic process GO:0009116 246 0.016
energy derivation by oxidation of organic compounds GO:0015980 77 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.016
midgut development GO:0007494 4 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
actin filament based movement GO:0030048 23 0.016
positive regulation of protein modification process GO:0031401 299 0.015
metal ion homeostasis GO:0055065 189 0.015
sequestering of metal ion GO:0051238 19 0.015
retina development in camera type eye GO:0060041 119 0.015
regulation of proteolysis GO:0030162 164 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
regulation of body fluid levels GO:0050878 162 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
chemotaxis GO:0006935 247 0.015
nucleotide catabolic process GO:0009166 217 0.015
lens development in camera type eye GO:0002088 62 0.015
lung development GO:0030324 164 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
neuron neuron synaptic transmission GO:0007270 69 0.015
organic acid transport GO:0015849 101 0.015
cardiac chamber development GO:0003205 108 0.015
cellular response to lipid GO:0071396 145 0.015
oocyte construction GO:0007308 2 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
segmentation GO:0035282 93 0.015
dibenzo p dioxin metabolic process GO:0018894 1 0.015
monoamine transport GO:0015844 33 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
regulation of smoothened signaling pathway GO:0008589 58 0.015
fat cell proliferation GO:0070341 4 0.014
protein homooligomerization GO:0051260 43 0.014
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.014
negative regulation of neuron projection regeneration GO:0070571 3 0.014
regulation of muscle tissue development GO:1901861 97 0.014
muscle cell development GO:0055001 133 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
protein secretion GO:0009306 111 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
anion transmembrane transport GO:0098656 71 0.014
negative regulation of endothelial cell migration GO:0010596 4 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
septum primum development GO:0003284 4 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
regulation of systemic arterial blood pressure GO:0003073 61 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
response to organic cyclic compound GO:0014070 198 0.014
cell cell recognition GO:0009988 44 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
Mouse
positive regulation of nervous system development GO:0051962 221 0.014
mesodermal cell migration GO:0008078 4 0.014
cellular amine metabolic process GO:0044106 44 0.014
synaptic transmission GO:0007268 329 0.014
adult locomotory behavior GO:0008344 91 0.014
cytosolic calcium ion homeostasis GO:0051480 70 0.014
regulation of defense response GO:0031347 233 0.014
Mouse
cellular amide metabolic process GO:0043603 58 0.014
regulation of voltage gated calcium channel activity GO:1901385 4 0.014
ensheathment of neurons GO:0007272 76 0.014
glycosyl compound metabolic process GO:1901657 246 0.013
leukocyte mediated immunity GO:0002443 174 0.013
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.013
learning GO:0007612 98 0.013
negative regulation of defense response GO:0031348 77 0.013
Mouse
myeloid cell homeostasis GO:0002262 114 0.013
Mouse
lipid localization GO:0010876 126 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
embryonic camera type eye development GO:0031076 36 0.013
nuclear division GO:0000280 158 0.013
av node cell to bundle of his cell communication GO:0086067 2 0.013
response to radiation GO:0009314 165 0.013
associative learning GO:0008306 61 0.013
defense response to bacterium GO:0042742 119 0.013
negative regulation of feeding behavior GO:2000252 1 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
negative regulation of neuron projection development GO:0010977 50 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
developmental maturation GO:0021700 193 0.013
adult behavior GO:0030534 135 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
epithelial cell development GO:0002064 159 0.013
purine ribonucleotide biosynthetic process GO:0009152 59 0.013
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.013
tissue remodeling GO:0048771 102 0.013
positive regulation of viral genome replication GO:0045070 2 0.013
Mouse
regulation of homeostatic process GO:0032844 182 0.013
synapse organization GO:0050808 125 0.013
cardiac chamber morphogenesis GO:0003206 93 0.013
cerebral cortex development GO:0021987 86 0.013
feeding behavior GO:0007631 62 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.012
atrial ventricular junction remodeling GO:0003294 2 0.012
ear development GO:0043583 200 0.012
germ cell development GO:0007281 185 0.012
cell cell signaling involved in lung development GO:0060495 1 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
Mouse
cell recognition GO:0008037 83 0.012
regulation of cytokine secretion GO:0050707 61 0.012
regulation of stem cell proliferation GO:0072091 78 0.012
appendage development GO:0048736 166 0.012
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
positive regulation of neural precursor cell proliferation GO:2000179 42 0.012
regulation of white fat cell proliferation GO:0070350 2 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
positive regulation of stem cell proliferation GO:2000648 59 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of hydrolase activity GO:0051336 246 0.012
digestive system development GO:0055123 200 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
negative regulation of secretion by cell GO:1903531 54 0.012
regulation of fat cell proliferation GO:0070344 4 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
telencephalon development GO:0021537 186 0.012
cell migration involved in gastrulation GO:0042074 13 0.012
regulation of vitamin metabolic process GO:0030656 3 0.012
striated muscle tissue development GO:0014706 293 0.012
skeletal muscle organ development GO:0060538 163 0.012
regulation of blood pressure GO:0008217 93 0.012
regulation of isoprenoid metabolic process GO:0019747 1 0.012
positive regulation of activin receptor signaling pathway GO:0032927 3 0.012
ossification GO:0001503 216 0.012
spinal cord development GO:0021510 81 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
regulation of circadian rhythm GO:0042752 58 0.012
response to endoplasmic reticulum stress GO:0034976 53 0.012
regulation of protein transport GO:0051223 163 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
stem cell maintenance GO:0019827 130 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
vitamin d biosynthetic process GO:0042368 3 0.012
binding of sperm to zona pellucida GO:0007339 34 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
regulation of calcium ion transport GO:0051924 69 0.011
heart morphogenesis GO:0003007 178 0.011
striated muscle cell development GO:0055002 125 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.011
reflex GO:0060004 22 0.011
spinal cord motor neuron differentiation GO:0021522 35 0.011
cell maturation GO:0048469 127 0.011
inflammatory response GO:0006954 244 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
cardiac septum development GO:0003279 59 0.011
epithelial tube formation GO:0072175 130 0.011
l amino acid transport GO:0015807 32 0.011
skeletal system development GO:0001501 356 0.011
oogenesis GO:0048477 56 0.011
ventral spinal cord development GO:0021517 48 0.011
leukocyte migration GO:0050900 124 0.011
b cell differentiation GO:0030183 78 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
regulation of organelle organization GO:0033043 289 0.011
regulation of tube size GO:0035150 57 0.011
phospholipid metabolic process GO:0006644 87 0.011
mitotic cell cycle GO:0000278 195 0.011
cyclic purine nucleotide metabolic process GO:0052652 43 0.011
regulation of high voltage gated calcium channel activity GO:1901841 2 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of protein secretion GO:0050708 82 0.011
cellular amino acid metabolic process GO:0006520 103 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
negative regulation of secretion GO:0051048 61 0.011
response to acid chemical GO:0001101 111 0.011
peptide hormone secretion GO:0030072 109 0.011
cardiac muscle tissue development GO:0048738 130 0.011
water transport GO:0006833 12 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
catecholamine metabolic process GO:0006584 30 0.011
cellular protein complex assembly GO:0043623 116 0.010
Mouse
carbohydrate homeostasis GO:0033500 128 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
cell differentiation in spinal cord GO:0021515 53 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
positive regulation of cytokine production GO:0001819 174 0.010
positive regulation of antimicrobial humoral response GO:0002760 2 0.010
foramen ovale closure GO:0035922 1 0.010
visual behavior GO:0007632 45 0.010
chromatin organization GO:0006325 206 0.010
lateral line system development GO:0048925 1 0.010
organic acid biosynthetic process GO:0016053 86 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.010
skin development GO:0043588 220 0.010
regulation of antimicrobial humoral response GO:0002759 3 0.010

Trim61 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
central nervous system disease DOID:331 0 0.020
cardiovascular system disease DOID:1287 0 0.010