Mus musculus

47 known processes

Mstn

myostatin

(Aliases: MGC124263,Gdf8,Cmpt,MGC124262,MGC124261)

Mstn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle fiber development GO:0048747 76 0.954
response to transforming growth factor beta GO:0071559 88 0.936
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.913
skeletal system development GO:0001501 356 0.872
Mouse
response to growth factor GO:0070848 198 0.866
muscle cell development GO:0055001 133 0.840
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.801
striated muscle cell development GO:0055002 125 0.740
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.740
muscle cell differentiation GO:0042692 261 0.686
regulation of protein binding GO:0043393 60 0.660
negative regulation of dna binding GO:0043392 20 0.640
regulation of binding GO:0051098 111 0.636
Mouse
response to inactivity GO:0014854 4 0.559
sperm ejaculation GO:0042713 1 0.469
positive regulation of kinase activity GO:0033674 155 0.450
regulation of cellular amine metabolic process GO:0033238 20 0.449
negative regulation of molecular function GO:0044092 258 0.443
regulation of system process GO:0044057 200 0.404
Rat
defense response to other organism GO:0098542 197 0.400
Worm
hair cycle GO:0042633 90 0.377
Mouse
regulation of muscle system process GO:0090257 80 0.345
Rat
odontogenesis GO:0042476 78 0.344
Mouse
positive regulation of triglyceride catabolic process GO:0010898 3 0.330
cellular response to glucocorticoid stimulus GO:0071385 13 0.311
skin morphogenesis GO:0043589 38 0.310
Mouse
response to steroid hormone GO:0048545 56 0.305
cellular amino acid metabolic process GO:0006520 103 0.304
negative regulation of lipid catabolic process GO:0050995 6 0.291
peptide hormone secretion GO:0030072 109 0.279
cytoskeleton dependent intracellular transport GO:0030705 50 0.278
response to muscle inactivity involved in regulation of muscle adaptation GO:0014877 4 0.268
negative regulation of binding GO:0051100 39 0.248
hair follicle development GO:0001942 85 0.243
Mouse
microtubule based transport GO:0010970 50 0.234
muscle system process GO:0003012 141 0.230
Rat
peptide transport GO:0015833 133 0.219
microtubule based process GO:0007017 236 0.207
response to denervation involved in regulation of muscle adaptation GO:0014894 4 0.205
response to corticosteroid GO:0031960 20 0.202
negative regulation of protein binding GO:0032091 17 0.193
insemination GO:0007320 6 0.187
peptide secretion GO:0002790 114 0.186
glial cell differentiation GO:0010001 131 0.177
regulation of organelle organization GO:0033043 289 0.175
Mouse
epidermis development GO:0008544 187 0.168
Mouse
cellular homeostasis GO:0019725 240 0.167
Mouse
multicellular organism growth GO:0035264 161 0.165
response to organic cyclic compound GO:0014070 198 0.164
bmp signaling pathway GO:0030509 93 0.164
mesenchymal cell differentiation GO:0048762 107 0.163
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.162
cellular amine metabolic process GO:0044106 44 0.158
cation transport GO:0006812 399 0.156
Mouse
protein import into nucleus GO:0006606 95 0.156
Mouse
single organism nuclear import GO:1902593 95 0.153
Mouse
response to dexamethasone GO:0071548 8 0.150
positive regulation of chromatin modification GO:1903310 28 0.141
Mouse
muscle adaptation GO:0043500 39 0.138
Rat
embryonic skeletal system development GO:0048706 120 0.137
extracellular structure organization GO:0043062 148 0.135
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.134
regulation of protein import into nucleus GO:0042306 52 0.132
Mouse
positive regulation of protein modification process GO:0031401 299 0.132
Mouse
cellular chemical homeostasis GO:0055082 215 0.132
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.131
cellular response to lipid GO:0071396 145 0.131
regulation of intracellular transport GO:0032386 159 0.129
Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.129
Mouse
modification dependent protein catabolic process GO:0019941 133 0.128
positive regulation of transferase activity GO:0051347 167 0.127
cytoplasmic transport GO:0016482 234 0.124
Mouse
regulation of activin receptor signaling pathway GO:0032925 10 0.120
regulation of cellular amino acid metabolic process GO:0006521 5 0.118
regulation of chromosome organization GO:0033044 83 0.118
Mouse
response to muscle inactivity GO:0014870 4 0.117
ossification GO:0001503 216 0.116
Mouse
protein localization to organelle GO:0033365 185 0.116
Mouse
keratinocyte proliferation GO:0043616 21 0.113
acylglycerol catabolic process GO:0046464 11 0.112
positive regulation of cell death GO:0010942 224 0.112
Mouse
cellular response to alcohol GO:0097306 23 0.112
stem cell development GO:0048864 219 0.109
Mouse
multicellular organismal homeostasis GO:0048871 164 0.108
amide transport GO:0042886 138 0.106
circulatory system process GO:0003013 197 0.105
regulation of apoptotic signaling pathway GO:2001233 197 0.105
Mouse
fat cell differentiation GO:0045444 160 0.104
regulation of muscle adaptation GO:0043502 31 0.104
positive regulation of cellular amine metabolic process GO:0033240 5 0.103
microtubule based movement GO:0007018 84 0.103
regulation of ion transport GO:0043269 215 0.100
Mouse
detection of stimulus GO:0051606 84 0.100
nucleocytoplasmic transport GO:0006913 139 0.099
Mouse
negative regulation of protein complex disassembly GO:0043242 22 0.098
multicellular organismal signaling GO:0035637 91 0.097
sodium ion transport GO:0006814 73 0.097
Mouse
regulation of membrane potential GO:0042391 192 0.096
regulation of monooxygenase activity GO:0032768 7 0.096
regulation of chromatin modification GO:1903308 57 0.095
Mouse
extracellular matrix organization GO:0030198 147 0.095
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.094
regulation of blood pressure GO:0008217 93 0.093
cellular response to cadmium ion GO:0071276 3 0.089
ear development GO:0043583 200 0.089
stem cell differentiation GO:0048863 268 0.089
Mouse
methylation GO:0032259 134 0.088
cartilage development GO:0051216 140 0.088
Mouse
negative regulation of cell proliferation GO:0008285 296 0.088
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.088
hematopoietic progenitor cell differentiation GO:0002244 143 0.088
metal ion homeostasis GO:0055065 189 0.087
Mouse
cellular response to hormone stimulus GO:0032870 150 0.087
reactive oxygen species metabolic process GO:0072593 84 0.087
microtubule cytoskeleton organization GO:0000226 157 0.087
covalent chromatin modification GO:0016569 163 0.086
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.086
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
regulation of cytoplasmic transport GO:1903649 112 0.085
Mouse
macromolecule methylation GO:0043414 120 0.084
positive regulation of programmed cell death GO:0043068 218 0.083
Mouse
microtubule polymerization or depolymerization GO:0031109 26 0.083
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.082
negative regulation of cell cycle GO:0045786 123 0.082
Mouse
epidermis morphogenesis GO:0048730 33 0.081
Mouse
hormone secretion GO:0046879 128 0.080
chromatin modification GO:0016568 187 0.080
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.079
striated muscle tissue development GO:0014706 293 0.078
Mouse Rat
positive regulation of histone modification GO:0031058 28 0.077
Mouse
negative regulation of protein depolymerization GO:1901880 21 0.076
epithelial tube morphogenesis GO:0060562 303 0.076
Mouse
homeostasis of number of cells GO:0048872 210 0.075
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.073
positive regulation of chromosome organization GO:2001252 33 0.073
Mouse
wnt signaling pathway GO:0016055 188 0.073
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.073
regulation of establishment of protein localization GO:0070201 181 0.072
Mouse
vascular process in circulatory system GO:0003018 62 0.072
positive regulation of protein kinase activity GO:0045860 144 0.072
amine metabolic process GO:0009308 45 0.072
regulation of microtubule based process GO:0032886 52 0.072
negative regulation of cellular component organization GO:0051129 194 0.071
mesenchyme development GO:0060485 152 0.071
Mouse
cellular response to steroid hormone stimulus GO:0071383 33 0.071
muscle tissue development GO:0060537 308 0.071
Mouse Rat
positive regulation of triglyceride metabolic process GO:0090208 9 0.071
monosaccharide metabolic process GO:0005996 106 0.070
cellular response to organonitrogen compound GO:0071417 145 0.069
intracellular protein transport GO:0006886 204 0.069
Mouse
cellular lipid catabolic process GO:0044242 52 0.068
protein modification by small protein conjugation GO:0032446 187 0.066
gliogenesis GO:0042063 141 0.066
embryonic skeletal system morphogenesis GO:0048704 91 0.066
transmission of nerve impulse GO:0019226 76 0.066
progesterone secretion GO:0042701 1 0.065
myotube cell development GO:0014904 60 0.065
establishment of blood nerve barrier GO:0008065 3 0.064
insulin secretion GO:0030073 89 0.064
skeletal muscle organ development GO:0060538 163 0.064
Rat
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.063
hexose metabolic process GO:0019318 98 0.063
calcium ion homeostasis GO:0055074 127 0.063
Mouse
lipid transport GO:0006869 98 0.062
triglyceride catabolic process GO:0019433 9 0.062
palate development GO:0060021 76 0.062
Mouse
protein import GO:0017038 101 0.062
Mouse
response to nutrient levels GO:0031667 109 0.062
protein kinase b signaling GO:0043491 74 0.061
nuclear import GO:0051170 95 0.061
Mouse
activin receptor signaling pathway GO:0032924 18 0.061
cellular ketone metabolic process GO:0042180 84 0.061
endothelium development GO:0003158 45 0.061
positive regulation of protein phosphorylation GO:0001934 242 0.061
myeloid cell homeostasis GO:0002262 114 0.061
ovulation cycle GO:0042698 59 0.060
Rat
histone modification GO:0016570 159 0.060
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.060
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.060
organelle assembly GO:0070925 177 0.060
spermatogenesis GO:0007283 284 0.060
response to stimulus involved in regulation of muscle adaptation GO:0014874 6 0.059
protein modification by small protein conjugation or removal GO:0070647 207 0.058
establishment of glial blood brain barrier GO:0060857 2 0.057
neuron projection guidance GO:0097485 141 0.056
Mouse
protein alkylation GO:0008213 81 0.056
digestive system development GO:0055123 200 0.055
regulation of transferase activity GO:0051338 263 0.055
locomotory behavior GO:0007626 195 0.054
inner ear morphogenesis GO:0042472 101 0.054
positive regulation of apoptotic signaling pathway GO:2001235 95 0.054
Mouse
regulation of intracellular protein transport GO:0033157 82 0.053
Mouse
regulation of ovulation GO:0060278 3 0.053
histone methylation GO:0016571 71 0.053
regulation of microtubule depolymerization GO:0031114 13 0.052
regulation of protein targeting GO:1903533 61 0.052
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.051
connective tissue development GO:0061448 179 0.051
Mouse
regulation of cell motility GO:2000145 236 0.050
macromolecular complex disassembly GO:0032984 43 0.050
renal system development GO:0072001 225 0.050
Mouse
negative regulation of microtubule depolymerization GO:0007026 13 0.050
positive regulation of homeostatic process GO:0032846 64 0.049
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.049
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.049
Mouse
neural crest cell development GO:0014032 48 0.049
protein depolymerization GO:0051261 34 0.049
negative regulation of cytoskeleton organization GO:0051494 36 0.049
odontogenesis of dentin containing tooth GO:0042475 66 0.048
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.048
Mouse
nitrogen compound transport GO:0071705 271 0.048
negative regulation of intracellular signal transduction GO:1902532 167 0.047
cellular ion homeostasis GO:0006873 165 0.047
Mouse
regulation of neuron projection development GO:0010975 169 0.047
response to alcohol GO:0097305 48 0.047
regulation of peptide transport GO:0090087 91 0.047
apoptotic signaling pathway GO:0097190 306 0.047
Mouse
protein methylation GO:0006479 81 0.046
response to lipopolysaccharide GO:0032496 128 0.046
negative regulation of peptide hormone secretion GO:0090278 16 0.046
organelle localization GO:0051640 179 0.044
membrane organization GO:0061024 245 0.044
regulation of voltage gated calcium channel activity GO:1901385 4 0.044
positive regulation of vasoconstriction GO:0045907 4 0.044
smooth muscle contraction GO:0006939 44 0.044
cellular divalent inorganic cation homeostasis GO:0072503 127 0.043
Mouse
wound healing GO:0042060 157 0.043
Rat
regulation of multicellular organismal metabolic process GO:0044246 14 0.043
Mouse
carbohydrate metabolic process GO:0005975 230 0.043
regulation of multi organism process GO:0043900 111 0.043
regulation of cellular catabolic process GO:0031329 242 0.042
mitotic cell cycle process GO:1903047 159 0.042
regulation of t cell proliferation GO:0042129 92 0.042
Mouse
retina development in camera type eye GO:0060041 119 0.042
protein complex disassembly GO:0043241 40 0.042
generation of precursor metabolites and energy GO:0006091 103 0.042
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.041
Mouse
ear morphogenesis GO:0042471 118 0.041
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.041
lymphocyte proliferation GO:0046651 164 0.040
Mouse
gene silencing by mirna GO:0035195 10 0.040
central nervous system neuron differentiation GO:0021953 162 0.040
myeloid cell differentiation GO:0030099 233 0.040
Mouse
energy derivation by oxidation of organic compounds GO:0015980 77 0.040
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.040
negative regulation of activin receptor signaling pathway GO:0032926 6 0.040
negative regulation of hormone secretion GO:0046888 20 0.039
peptidyl amino acid modification GO:0018193 336 0.039
Mouse
cellular response to leptin stimulus GO:0044320 6 0.039
endomembrane system organization GO:0010256 147 0.039
ameboidal type cell migration GO:0001667 128 0.038
response to peptide hormone GO:0043434 127 0.038
response to drug GO:0042493 75 0.038
plasma membrane organization GO:0007009 90 0.038
glycerolipid catabolic process GO:0046503 16 0.038
negative regulation of growth GO:0045926 99 0.038
Mouse Rat
chemotaxis GO:0006935 247 0.038
Mouse
cytokine production GO:0001816 319 0.038
Mouse
actin cytoskeleton organization GO:0030036 220 0.038
Mouse
phenol containing compound metabolic process GO:0018958 60 0.038
Mouse
molting cycle GO:0042303 90 0.038
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.038
Mouse
protein ubiquitination GO:0016567 171 0.037
determination of left right symmetry GO:0007368 80 0.037
positive regulation of organelle organization GO:0010638 128 0.037
Mouse
otic placode formation GO:0043049 1 0.037
regulation of histone modification GO:0031056 56 0.037
Mouse
regulation of protein kinase b signaling GO:0051896 56 0.036
cellular calcium ion homeostasis GO:0006874 119 0.036
Mouse
response to radiation GO:0009314 165 0.036
microtubule depolymerization GO:0007019 15 0.036
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.035
axon ensheathment GO:0008366 76 0.035
divalent metal ion transport GO:0070838 172 0.035
feeding behavior GO:0007631 62 0.035
Worm
oxidation reduction process GO:0055114 342 0.035
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.035
cellular respiration GO:0045333 38 0.035
regulation of fat cell differentiation GO:0045598 81 0.035
response to organonitrogen compound GO:0010243 246 0.034
pancreas development GO:0031016 57 0.034
Mouse
regulation of neuron differentiation GO:0045664 281 0.034
lipid catabolic process GO:0016042 69 0.034
negative regulation of immune system process GO:0002683 209 0.033
Mouse
leukocyte proliferation GO:0070661 172 0.033
Mouse
ovarian follicle development GO:0001541 40 0.033
lipid particle organization GO:0034389 7 0.033
regulation of protein depolymerization GO:1901879 26 0.033
heart process GO:0003015 94 0.033
protein localization to membrane GO:0072657 108 0.033
response to glucocorticoid GO:0051384 20 0.033
reactive nitrogen species metabolic process GO:2001057 0 0.032
mapk cascade GO:0000165 281 0.032
glucose homeostasis GO:0042593 128 0.032
muscle contraction GO:0006936 101 0.032
regulation of homeostatic process GO:0032844 182 0.032
Mouse
male gamete generation GO:0048232 285 0.032
response to light stimulus GO:0009416 135 0.032
cellular protein catabolic process GO:0044257 155 0.032
development of primary sexual characteristics GO:0045137 143 0.032
heart morphogenesis GO:0003007 178 0.032
posttranscriptional regulation of gene expression GO:0010608 155 0.032
canonical wnt signaling pathway GO:0060070 130 0.031
macromolecule catabolic process GO:0009057 281 0.031
innate immune response GO:0045087 157 0.031
norepinephrine secretion GO:0048243 2 0.031
cation homeostasis GO:0055080 212 0.031
Mouse
skeletal system morphogenesis GO:0048705 203 0.031
Mouse
positive regulation of nervous system development GO:0051962 221 0.031
regulation of tube size GO:0035150 57 0.030
striated muscle contraction GO:0006941 45 0.030
regulation of chromatin organization GO:1902275 57 0.030
Mouse
keratinocyte migration GO:0051546 3 0.030
mitochondrion organization GO:0007005 134 0.030
positive regulation of behavior GO:0048520 40 0.030
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.030
g protein coupled receptor signaling pathway GO:0007186 243 0.030
positive regulation of ossification GO:0045778 47 0.030
action potential GO:0001508 78 0.029
respiratory tube development GO:0030323 167 0.029
positive regulation of cell development GO:0010720 237 0.029
Mouse
regulation of hormone secretion GO:0046883 88 0.029
cellular metal ion homeostasis GO:0006875 151 0.029
Mouse
regulation of protein transport GO:0051223 163 0.029
Mouse
pigmentation GO:0043473 71 0.029
morphogenesis of a branching epithelium GO:0061138 193 0.029
Mouse
regulation of microtubule cytoskeleton organization GO:0070507 37 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.028
regulation of muscle contraction GO:0006937 49 0.028
spinal cord development GO:0021510 81 0.028
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.028
positive regulation of secretion GO:0051047 130 0.028
cellular lipid metabolic process GO:0044255 323 0.028
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.028
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
regulation of synaptic activity GO:0060025 1 0.028
myotube differentiation GO:0014902 105 0.028
chromatin organization GO:0006325 206 0.027
Mouse
cell substrate adhesion GO:0031589 130 0.027
regulation of nucleocytoplasmic transport GO:0046822 73 0.027
Mouse
response to extracellular stimulus GO:0009991 127 0.027
actin cytoskeleton reorganization GO:0031532 21 0.027
Mouse
regulation of organ morphogenesis GO:2000027 144 0.027
Mouse
adult locomotory behavior GO:0008344 91 0.026
mesoderm development GO:0007498 100 0.026
development of primary male sexual characteristics GO:0046546 88 0.026
mammary gland morphogenesis GO:0060443 54 0.026
Mouse
second messenger mediated signaling GO:0019932 73 0.026
epithelial cell proliferation GO:0050673 174 0.026
modification by symbiont of host morphology or physiology GO:0044003 4 0.026
skeletal muscle fiber development GO:0048741 58 0.026
regulation of proteolysis GO:0030162 164 0.026
digestive tract development GO:0048565 190 0.026
regulation of histone methylation GO:0031060 30 0.026
negative regulation of cytokine production GO:0001818 84 0.025
protein targeting GO:0006605 143 0.025
Mouse
regulation of feeding behavior GO:0060259 3 0.025
Worm
t cell proliferation GO:0042098 120 0.025
Mouse
ensheathment of neurons GO:0007272 76 0.025
negative regulation of lymphocyte proliferation GO:0050672 45 0.025
Mouse
negative regulation of phosphorylation GO:0042326 166 0.025
somitogenesis GO:0001756 69 0.024
single organism cell adhesion GO:0098602 156 0.024
sensory perception of light stimulus GO:0050953 54 0.024
regulation of lipid metabolic process GO:0019216 118 0.024
regulation of anatomical structure size GO:0090066 178 0.024
ion transmembrane transport GO:0034220 361 0.024
regulation of triglyceride metabolic process GO:0090207 17 0.024
regulation of protein serine threonine kinase activity GO:0071900 157 0.024
inorganic ion transmembrane transport GO:0098660 234 0.023
germ cell development GO:0007281 185 0.023
synaptic transmission GO:0007268 329 0.023
regulation of innate immune response GO:0045088 91 0.023
bone development GO:0060348 120 0.023
regulation of myotube differentiation GO:0010830 62 0.023
cellular protein complex disassembly GO:0043624 36 0.023
neuron death GO:0070997 154 0.023
skin development GO:0043588 220 0.023
Mouse
protein localization to nucleus GO:0034504 121 0.023
Mouse
peptide metabolic process GO:0006518 46 0.023
adaptive immune response GO:0002250 155 0.023
Mouse
multi multicellular organism process GO:0044706 109 0.022
digestive tract morphogenesis GO:0048546 147 0.022
myelination GO:0042552 74 0.022
proteasomal protein catabolic process GO:0010498 98 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
regulation of ion transmembrane transport GO:0034765 119 0.022
peptidyl serine modification GO:0018209 83 0.022
maintenance of location GO:0051235 89 0.022
aromatic compound catabolic process GO:0019439 286 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
Mouse
t cell activation GO:0042110 289 0.022
Mouse
response to molecule of bacterial origin GO:0002237 143 0.022
leukocyte mediated immunity GO:0002443 174 0.022
cytosolic calcium ion homeostasis GO:0051480 70 0.022
regulation of lipid catabolic process GO:0050994 15 0.022
regulation of lipid storage GO:0010883 20 0.022
divalent inorganic cation transport GO:0072511 178 0.022
cardiac muscle tissue development GO:0048738 130 0.022
regulation of neuron apoptotic process GO:0043523 122 0.021
development of primary female sexual characteristics GO:0046545 73 0.021
positive regulation of activin receptor signaling pathway GO:0032927 3 0.021
anion transport GO:0006820 177 0.021
leukocyte apoptotic process GO:0071887 71 0.021
Mouse
neuronal action potential GO:0019228 54 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
synapse organization GO:0050808 125 0.021
cellular response to corticosteroid stimulus GO:0071384 13 0.021
lipid localization GO:0010876 126 0.021
negative regulation of ossification GO:0030279 49 0.021
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
immune effector process GO:0002252 321 0.021
vesicle organization GO:0016050 60 0.021
mitotic cell cycle GO:0000278 195 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
cellular response to oxidative stress GO:0034599 76 0.021
gastrulation with mouth forming second GO:0001702 29 0.021
regulation of epidermis development GO:0045682 33 0.021
actomyosin structure organization GO:0031032 56 0.021
multicellular organismal metabolic process GO:0044236 28 0.021
Mouse
calcium ion transport GO:0006816 159 0.021
regulation of peptidyl lysine acetylation GO:2000756 22 0.021
Mouse
regulation of neuron death GO:1901214 134 0.021
gonad development GO:0008406 141 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
Mouse
dna metabolic process GO:0006259 303 0.020
protein acylation GO:0043543 64 0.020
Mouse
biomineral tissue development GO:0031214 64 0.020
peptidyl cysteine s nitrosylation GO:0018119 4 0.020
regulation of protein deacetylation GO:0090311 17 0.020
Mouse
hindbrain development GO:0030902 128 0.020
response to oxygen levels GO:0070482 62 0.020
blood vessel morphogenesis GO:0048514 285 0.020
vasoconstriction GO:0042310 27 0.020
regionalization GO:0003002 337 0.020
Mouse
gluconeogenesis GO:0006094 39 0.020
interleukin 17 production GO:0032620 11 0.019
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.019
cation transmembrane transport GO:0098655 266 0.019
regulation of striated muscle cell differentiation GO:0051153 81 0.019
iron ion homeostasis GO:0055072 36 0.019
negative regulation of protein modification process GO:0031400 163 0.019
regulation of autophagy GO:0010506 30 0.019
nuclear division GO:0000280 158 0.019
spermatid development GO:0007286 108 0.019
negative regulation of neuron death GO:1901215 98 0.019
negative regulation of cell motility GO:2000146 61 0.019
neutral lipid catabolic process GO:0046461 11 0.019
neural crest cell differentiation GO:0014033 54 0.019
glycosylation GO:0070085 62 0.019
protein maturation GO:0051604 176 0.019
otic vesicle development GO:0071599 14 0.019
regulation of smooth muscle contraction GO:0006940 22 0.019
positive regulation of epidermis development GO:0045684 13 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
negative regulation of t cell activation GO:0050868 65 0.018
Mouse
morphogenesis of a branching structure GO:0001763 203 0.018
Mouse
norepinephrine transport GO:0015874 2 0.018
interspecies interaction between organisms GO:0044419 83 0.018
nuclear transport GO:0051169 139 0.018
Mouse
regulation of secretion by cell GO:1903530 249 0.018
regulation of stem cell differentiation GO:2000736 50 0.018
Mouse
regulation of action potential GO:0098900 4 0.018
cellular response to starvation GO:0009267 57 0.018
negative regulation of endopeptidase activity GO:0010951 44 0.018
somite development GO:0061053 81 0.018
regulation of response to wounding GO:1903034 189 0.018
cell adhesion GO:0007155 329 0.018
peptidyl tyrosine phosphorylation GO:0018108 143 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
neural tube development GO:0021915 160 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
Mouse
response to cholesterol GO:0070723 4 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
negative regulation of cell migration GO:0030336 59 0.017
retina vasculature development in camera type eye GO:0061298 17 0.017

Mstn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.246
disease of anatomical entity DOID:7 0 0.246
musculoskeletal system disease DOID:17 0 0.246
muscle tissue disease DOID:66 0 0.246
disease of metabolism DOID:0014667 0 0.199
myopathy DOID:423 0 0.126
diabetes mellitus DOID:9351 0 0.115
type 2 diabetes mellitus DOID:9352 0 0.115
carbohydrate metabolism disease DOID:0050013 0 0.115
glucose metabolism disease DOID:4194 0 0.115
acquired metabolic disease DOID:0060158 0 0.115
muscular dystrophy DOID:9884 0 0.114
cancer DOID:162 0 0.112
disease of cellular proliferation DOID:14566 0 0.112
organ system cancer DOID:0050686 0 0.112
heart disease DOID:114 0 0.108
cardiomyopathy DOID:0050700 0 0.108
intrinsic cardiomyopathy DOID:0060036 0 0.108
cardiovascular system disease DOID:1287 0 0.108
dilated cardiomyopathy DOID:12930 0 0.047
physical disorder DOID:0080015 0 0.029
limb girdle muscular dystrophy DOID:11724 0 0.026
nervous system disease DOID:863 0 0.017