Mus musculus

0 known processes

Lars

leucyl-tRNA synthetase

(Aliases: 2310045K21Rik,mKIAA1352,3110009L02Rik,AW536573)

Lars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trna metabolic process GO:0006399 11 0.990
Yeast
trna aminoacylation for protein translation GO:0006418 1 0.958
Yeast
amino acid activation GO:0043038 1 0.934
Yeast
translation GO:0006412 93 0.676
Yeast
trna aminoacylation GO:0043039 1 0.634
Yeast
cellular amino acid metabolic process GO:0006520 103 0.483
Yeast
cytoplasmic translational initiation GO:0002183 3 0.429
dna repair GO:0006281 107 0.124
cytoplasmic transport GO:0016482 234 0.095
aromatic compound catabolic process GO:0019439 286 0.083
translational initiation GO:0006413 24 0.078
ncrna processing GO:0034470 26 0.070
mitotic cell cycle GO:0000278 195 0.064
cellular nitrogen compound catabolic process GO:0044270 280 0.063
regulation of mitotic cell cycle GO:0007346 126 0.062
heterocycle catabolic process GO:0046700 280 0.060
ribonucleotide catabolic process GO:0009261 208 0.050
membrane organization GO:0061024 245 0.049
organelle assembly GO:0070925 177 0.046
regulation of cell cycle GO:0051726 281 0.044
ribonucleoside metabolic process GO:0009119 245 0.042
cellular ketone metabolic process GO:0042180 84 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
nucleoside phosphate catabolic process GO:1901292 222 0.040
mitotic cell cycle process GO:1903047 159 0.039
nitrogen compound transport GO:0071705 271 0.039
trna wobble base modification GO:0002097 2 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
organophosphate catabolic process GO:0046434 232 0.034
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
nucleoside metabolic process GO:0009116 246 0.033
cellular amine metabolic process GO:0044106 44 0.032
nuclear transport GO:0051169 139 0.032
regulation of membrane potential GO:0042391 192 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
organelle fission GO:0048285 170 0.029
nucleocytoplasmic transport GO:0006913 139 0.029
nuclear export GO:0051168 34 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.029
folic acid containing compound metabolic process GO:0006760 3 0.029
action potential GO:0001508 78 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
dna dealkylation GO:0035510 11 0.028
nucleoside catabolic process GO:0009164 206 0.027
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
multicellular organismal signaling GO:0035637 91 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
cell growth GO:0016049 130 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
nucleotide catabolic process GO:0009166 217 0.026
organelle localization GO:0051640 179 0.026
regulation of organelle organization GO:0033043 289 0.026
spindle organization GO:0007051 28 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
regulation of translation GO:0006417 71 0.025
neuron apoptotic process GO:0051402 142 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
purine containing compound metabolic process GO:0072521 311 0.024
cellular hyperosmotic salinity response GO:0071475 0 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
nuclear division GO:0000280 158 0.022
double strand break repair via nonhomologous end joining GO:0006303 10 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
organelle disassembly GO:1903008 2 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
regulation of cell cycle process GO:0010564 160 0.022
apoptotic signaling pathway GO:0097190 306 0.021
nucleotide metabolic process GO:0009117 332 0.020
response to acid chemical GO:0001101 111 0.020
lateral inhibition GO:0046331 1 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
maintenance of location GO:0051235 89 0.020
mrna transport GO:0051028 13 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
cation transmembrane transport GO:0098655 266 0.020
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.019
amine metabolic process GO:0009308 45 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
spindle assembly involved in mitosis GO:0090307 4 0.019
cell adhesion GO:0007155 329 0.019
glycoprotein metabolic process GO:0009100 116 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
cell type specific apoptotic process GO:0097285 268 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
methylation GO:0032259 134 0.018
neuronal action potential GO:0019228 54 0.018
neuron death GO:0070997 154 0.018
molting cycle GO:0042303 90 0.018
positive regulation of cell death GO:0010942 224 0.017
maturation of 5 8s rrna GO:0000460 1 0.017
epidermis development GO:0008544 187 0.017
regulation of protein localization GO:0032880 231 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
protein folding GO:0006457 28 0.017
trna processing GO:0008033 11 0.017
regulation of neuron differentiation GO:0045664 281 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
mrna export from nucleus GO:0006406 11 0.016
axonogenesis GO:0007409 274 0.016
transmission of nerve impulse GO:0019226 76 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
protein targeting GO:0006605 143 0.015
stem cell differentiation GO:0048863 268 0.015
forebrain development GO:0030900 302 0.015
non recombinational repair GO:0000726 10 0.014
protein maturation GO:0051604 176 0.014
purine containing compound catabolic process GO:0072523 213 0.014
ncrna 3 end processing GO:0043628 2 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
response to organonitrogen compound GO:0010243 246 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
regulation of protein binding GO:0043393 60 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
nucleobase containing compound transport GO:0015931 27 0.014
regulation of cellular component size GO:0032535 121 0.014
macromolecule catabolic process GO:0009057 281 0.014
regulation of cell migration GO:0030334 219 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
germ cell development GO:0007281 185 0.014
microtubule based process GO:0007017 236 0.014
trna modification GO:0006400 9 0.014
double strand break repair GO:0006302 48 0.013
lipid localization GO:0010876 126 0.013
t cell activation GO:0042110 289 0.013
positive regulation of protein modification process GO:0031401 299 0.013
t cell proliferation GO:0042098 120 0.013
pancreas development GO:0031016 57 0.013
gland development GO:0048732 330 0.013
angiogenesis GO:0001525 201 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
dna metabolic process GO:0006259 303 0.013
protein import GO:0017038 101 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
regulation of kinase activity GO:0043549 249 0.013
endocytosis GO:0006897 168 0.013
endomembrane system organization GO:0010256 147 0.013
chemotaxis GO:0006935 247 0.013
cellular response to amino acid stimulus GO:0071230 29 0.012
regulation of intracellular transport GO:0032386 159 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
protein localization to organelle GO:0033365 185 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
regulation of cell division GO:0051302 76 0.012
rna interference GO:0016246 2 0.012
protein autophosphorylation GO:0046777 61 0.012
regulation of body fluid levels GO:0050878 162 0.012
glial cell differentiation GO:0010001 131 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
coenzyme metabolic process GO:0006732 52 0.012
macromolecule glycosylation GO:0043413 55 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
ion transmembrane transport GO:0034220 361 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
synapse organization GO:0050808 125 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
cellular protein complex assembly GO:0043623 116 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
glycosylation GO:0070085 62 0.011
liver development GO:0001889 66 0.011
cellular lipid metabolic process GO:0044255 323 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of cell motility GO:2000145 236 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
leukocyte migration GO:0050900 124 0.011
nuclear import GO:0051170 95 0.011
cell fate commitment GO:0045165 210 0.011
positive regulation of cell motility GO:2000147 116 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
response to insulin GO:0032868 100 0.011
compound eye development GO:0048749 1 0.011
ribosomal subunit export from nucleus GO:0000054 1 0.010
regulation of amyloid precursor protein biosynthetic process GO:0042984 3 0.010
positive regulation of nervous system development GO:0051962 221 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
atp metabolic process GO:0046034 75 0.010
muscle cell development GO:0055001 133 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
lymphocyte proliferation GO:0046651 164 0.010
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010
maintenance of protein location in nucleus GO:0051457 2 0.010
protein glycosylation GO:0006486 55 0.010
intracellular protein transport GO:0006886 204 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
ensheathment of neurons GO:0007272 76 0.010

Lars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.497
nervous system disease DOID:863 0 0.497
neuropathy DOID:870 0 0.497
neuromuscular disease DOID:440 0 0.485
charcot marie tooth disease DOID:10595 0 0.485
central nervous system disease DOID:331 0 0.035
neurodegenerative disease DOID:1289 0 0.035
charcot marie tooth disease type 2 DOID:0050539 0 0.032
retinal disease DOID:5679 0 0.021
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.021
retinal degeneration DOID:8466 0 0.015