Mus musculus

21 known processes

Sp8

trans-acting transcription factor 8

(Aliases: D930049B17Rik,mBtd,MGC105193)

Sp8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
forebrain development GO:0030900 302 0.522
regionalization GO:0003002 337 0.428
camera type eye development GO:0043010 266 0.295
Mouse
skeletal system development GO:0001501 356 0.251
Mouse
central nervous system neuron differentiation GO:0021953 162 0.226
telencephalon development GO:0021537 186 0.219
appendage development GO:0048736 166 0.213
positive regulation of non canonical wnt signaling pathway GO:2000052 6 0.211
embryonic limb morphogenesis GO:0030326 126 0.170
sensory organ morphogenesis GO:0090596 242 0.142
Mouse
limb development GO:0060173 166 0.133
cell proliferation in hindbrain GO:0021534 10 0.131
appendage morphogenesis GO:0035107 149 0.126
positive regulation of cell development GO:0010720 237 0.125
neural precursor cell proliferation GO:0061351 121 0.120
gland development GO:0048732 330 0.114
Mouse
eye photoreceptor cell development GO:0042462 31 0.114
respiratory tube development GO:0030323 167 0.113
Mouse
spinal cord development GO:0021510 81 0.110
bmp signaling pathway GO:0030509 93 0.110
stem cell development GO:0048864 219 0.110
stem cell differentiation GO:0048863 268 0.108
epithelial tube morphogenesis GO:0060562 303 0.108
wnt signaling pathway GO:0016055 188 0.105
regulation of cellular amino acid metabolic process GO:0006521 5 0.105
respiratory system development GO:0060541 190 0.100
Mouse
embryonic organ morphogenesis GO:0048562 276 0.097
Mouse
retina development in camera type eye GO:0060041 119 0.097
regulation of bmp signaling pathway GO:0030510 60 0.096
ossification GO:0001503 216 0.095
Mouse
amine metabolic process GO:0009308 45 0.094
hematopoietic progenitor cell differentiation GO:0002244 143 0.094
Mouse
endodermal cell fate specification GO:0001714 4 0.090
connective tissue development GO:0061448 179 0.089
cerebellar granule cell precursor proliferation GO:0021930 10 0.089
axonogenesis GO:0007409 274 0.085
blood vessel morphogenesis GO:0048514 285 0.084
limb morphogenesis GO:0035108 149 0.083
response to organonitrogen compound GO:0010243 246 0.083
primary neural tube formation GO:0014020 95 0.082
skeletal system morphogenesis GO:0048705 203 0.081
Mouse
nerve development GO:0021675 67 0.080
muscle cell differentiation GO:0042692 261 0.080
morphogenesis of embryonic epithelium GO:0016331 159 0.079
olfactory lobe development GO:0021988 32 0.079
forelimb morphogenesis GO:0035136 40 0.079
diencephalon development GO:0021536 63 0.078
auditory receptor cell fate determination GO:0042668 3 0.078
cell fate commitment GO:0045165 210 0.077
mesoderm development GO:0007498 100 0.076
neural tube closure GO:0001843 90 0.075
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.075
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 70 0.075
mapk cascade GO:0000165 281 0.074
cell proliferation in external granule layer GO:0021924 10 0.074
hindbrain development GO:0030902 128 0.073
transmembrane transport GO:0055085 412 0.072
cell differentiation in spinal cord GO:0021515 53 0.071
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.068
embryonic appendage morphogenesis GO:0035113 126 0.068
positive regulation of nervous system development GO:0051962 221 0.067
morphogenesis of a branching epithelium GO:0061138 193 0.067
limbic system development GO:0021761 72 0.067
muscle tissue development GO:0060537 308 0.065
neural tube formation GO:0001841 108 0.065
canonical wnt signaling pathway GO:0060070 130 0.064
sensory perception GO:0007600 245 0.064
epithelial cell morphogenesis GO:0003382 41 0.062
developmental growth involved in morphogenesis GO:0060560 138 0.061
somitogenesis GO:0001756 69 0.060
renal system development GO:0072001 225 0.059
cerebellum development GO:0021549 77 0.058
somite development GO:0061053 81 0.058
response to organic cyclic compound GO:0014070 198 0.058
cell fate specification GO:0001708 72 0.058
metencephalon development GO:0022037 89 0.057
nucleoside phosphate metabolic process GO:0006753 338 0.057
cellular amine metabolic process GO:0044106 44 0.057
neuron projection guidance GO:0097485 141 0.057
cellular response to organic cyclic compound GO:0071407 87 0.057
regulation of cellular ketone metabolic process GO:0010565 66 0.057
regulation of smoothened signaling pathway GO:0008589 58 0.054
striated muscle cell development GO:0055002 125 0.054
embryonic skeletal system development GO:0048706 120 0.054
Mouse
regulation of mapk cascade GO:0043408 248 0.053
g protein coupled receptor signaling pathway GO:0007186 243 0.053
striated muscle tissue development GO:0014706 293 0.053
pallium development GO:0021543 120 0.052
epithelial cell development GO:0002064 159 0.052
ear development GO:0043583 200 0.052
tube formation GO:0035148 140 0.052
branching morphogenesis of an epithelial tube GO:0048754 159 0.052
placenta development GO:0001890 140 0.051
Mouse
digestive system development GO:0055123 200 0.051
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.050
hindbrain morphogenesis GO:0021575 46 0.049
regulation of cell cycle process GO:0010564 160 0.049
regulation of neuron differentiation GO:0045664 281 0.049
cellular ketone metabolic process GO:0042180 84 0.048
myotube differentiation GO:0014902 105 0.048
cellular response to lipid GO:0071396 145 0.047
positive regulation of mapk cascade GO:0043410 170 0.047
cell type specific apoptotic process GO:0097285 268 0.047
retina morphogenesis in camera type eye GO:0060042 45 0.046
digestive tract development GO:0048565 190 0.046
neural retina development GO:0003407 41 0.045
lung development GO:0030324 164 0.045
Mouse
smoothened signaling pathway GO:0007224 105 0.045
apoptotic signaling pathway GO:0097190 306 0.045
ventral spinal cord development GO:0021517 48 0.045
epithelial to mesenchymal transition GO:0001837 47 0.044
mesenchyme development GO:0060485 152 0.044
trachea cartilage morphogenesis GO:0060535 4 0.044
embryonic skeletal system morphogenesis GO:0048704 91 0.043
organic cyclic compound catabolic process GO:1901361 295 0.043
tube closure GO:0060606 91 0.043
oxidation reduction process GO:0055114 342 0.042
morphogenesis of a branching structure GO:0001763 203 0.042
regulation of wnt signaling pathway GO:0030111 123 0.042
chemotaxis GO:0006935 247 0.042
oocyte axis specification GO:0007309 2 0.042
lipid transport GO:0006869 98 0.042
cell adhesion GO:0007155 329 0.042
regulation of cell activation GO:0050865 289 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
protein processing GO:0016485 163 0.041
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.041
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.041
regulation of organ morphogenesis GO:2000027 144 0.041
stem cell maintenance GO:0019827 130 0.041
organic hydroxy compound metabolic process GO:1901615 203 0.040
ras protein signal transduction GO:0007265 77 0.040
nephron morphogenesis GO:0072028 69 0.040
regulation of fat cell differentiation GO:0045598 81 0.040
cell differentiation in hindbrain GO:0021533 24 0.039
skeletal muscle organ development GO:0060538 163 0.039
inner ear receptor cell differentiation GO:0060113 61 0.039
negative regulation of cell cycle GO:0045786 123 0.039
axon guidance GO:0007411 141 0.039
posttranscriptional regulation of gene expression GO:0010608 155 0.038
reactive oxygen species metabolic process GO:0072593 84 0.038
cellular amino acid metabolic process GO:0006520 103 0.038
positive regulation of stem cell proliferation GO:2000648 59 0.038
ventral spinal cord interneuron differentiation GO:0021514 16 0.038
membrane organization GO:0061024 245 0.037
forebrain neuron differentiation GO:0021879 52 0.037
heterocycle catabolic process GO:0046700 280 0.037
regulation of stem cell proliferation GO:0072091 78 0.037
regulation of muscle tissue development GO:1901861 97 0.037
cartilage development GO:0051216 140 0.037
ion transmembrane transport GO:0034220 361 0.037
regulation of ossification GO:0030278 112 0.037
organelle fission GO:0048285 170 0.036
regulation of cell cycle GO:0051726 281 0.036
regulation of non canonical wnt signaling pathway GO:2000050 12 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
chondrocyte differentiation GO:0002062 72 0.036
somatotropin secreting cell differentiation GO:0060126 4 0.036
inner ear morphogenesis GO:0042472 101 0.036
locomotory behavior GO:0007626 195 0.036
single organism cell adhesion GO:0098602 156 0.036
steroid metabolic process GO:0008202 119 0.036
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.035
kidney development GO:0001822 213 0.035
nephron epithelium morphogenesis GO:0072088 68 0.035
nephron tubule development GO:0072080 84 0.035
bone mineralization GO:0030282 54 0.035
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.035
compound eye development GO:0048749 1 0.035
nuclear division GO:0000280 158 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
regulation of establishment of protein localization GO:0070201 181 0.034
cellular lipid metabolic process GO:0044255 323 0.034
nucleotide metabolic process GO:0009117 332 0.034
stem cell proliferation GO:0072089 117 0.034
kidney morphogenesis GO:0060993 83 0.034
purine containing compound metabolic process GO:0072521 311 0.034
formation of primary germ layer GO:0001704 77 0.034
purine containing compound catabolic process GO:0072523 213 0.034
cardiac muscle tissue development GO:0048738 130 0.034
positive regulation of protein modification process GO:0031401 299 0.034
olfactory bulb development GO:0021772 30 0.034
neuron migration GO:0001764 122 0.033
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.033
mammary placode formation GO:0060596 4 0.033
forebrain generation of neurons GO:0021872 63 0.033
anion transport GO:0006820 177 0.033
monocarboxylic acid metabolic process GO:0032787 191 0.033
non canonical wnt signaling pathway GO:0035567 33 0.033
cardiocyte differentiation GO:0035051 87 0.033
palate development GO:0060021 76 0.033
neural tube development GO:0021915 160 0.033
photoreceptor cell development GO:0042461 40 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.032
embryonic hindlimb morphogenesis GO:0035116 32 0.032
regulation of hydrolase activity GO:0051336 246 0.032
lipid biosynthetic process GO:0008610 179 0.032
regulation of peptidase activity GO:0052547 96 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
renal tubule development GO:0061326 87 0.032
urogenital system development GO:0001655 261 0.032
forebrain regionalization GO:0021871 25 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
embryonic epithelial tube formation GO:0001838 130 0.032
central nervous system neuron development GO:0021954 67 0.032
cardiac right ventricle formation GO:0003219 3 0.031
odontogenesis of dentin containing tooth GO:0042475 66 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
aromatic compound catabolic process GO:0019439 286 0.031
regulation of endopeptidase activity GO:0052548 89 0.031
mesonephric tubule development GO:0072164 94 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
digestive tract morphogenesis GO:0048546 147 0.031
cellular chemical homeostasis GO:0055082 215 0.031
regulation of glial cell differentiation GO:0045685 41 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
cardiac septum development GO:0003279 59 0.031
single organismal cell cell adhesion GO:0016337 131 0.031
regulation of protein localization GO:0032880 231 0.031
angiogenesis GO:0001525 201 0.030
regulation of canonical wnt signaling pathway GO:0060828 82 0.030
regulation of cytokine production GO:0001817 266 0.030
cellular component assembly involved in morphogenesis GO:0010927 139 0.030
autonomic nervous system development GO:0048483 43 0.030
spinal cord motor neuron differentiation GO:0021522 35 0.030
lateral line system development GO:0048925 1 0.030
photoreceptor cell differentiation GO:0046530 52 0.030
regulation of neuron projection development GO:0010975 169 0.030
cerebellar cortex development GO:0021695 48 0.030
embryonic forelimb morphogenesis GO:0035115 32 0.029
ureteric bud morphogenesis GO:0060675 62 0.029
negative regulation of molecular function GO:0044092 258 0.029
regulation of system process GO:0044057 200 0.029
Mouse
protein maturation GO:0051604 176 0.029
cilium morphogenesis GO:0060271 102 0.029
response to extracellular stimulus GO:0009991 127 0.029
neuron projection extension GO:1990138 64 0.029
embryonic digit morphogenesis GO:0042733 56 0.029
biomineral tissue development GO:0031214 64 0.029
tendon formation GO:0035992 4 0.029
regulation of embryonic development GO:0045995 71 0.028
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.028
carbohydrate homeostasis GO:0033500 128 0.028
regulation of protein maturation GO:1903317 96 0.028
pancreatic a cell fate commitment GO:0003326 2 0.028
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.028
regulation of cell adhesion GO:0030155 154 0.028
determination of left right symmetry GO:0007368 80 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
myotube cell development GO:0014904 60 0.027
peptidyl amino acid modification GO:0018193 336 0.027
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.027
response to acid chemical GO:0001101 111 0.027
tendon cell differentiation GO:0035990 4 0.027
epidermis development GO:0008544 187 0.027
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.027
cerebral cortex neuron differentiation GO:0021895 19 0.027
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.027
bone development GO:0060348 120 0.027
Mouse
spermatid differentiation GO:0048515 115 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
cell maturation GO:0048469 127 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
epithelial tube formation GO:0072175 130 0.026
endocytosis GO:0006897 168 0.026
neural tube patterning GO:0021532 43 0.026
lipid localization GO:0010876 126 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
extracellular structure organization GO:0043062 148 0.026
spinal cord dorsal ventral patterning GO:0021513 23 0.026
bone morphogenesis GO:0060349 78 0.026
Mouse
ribonucleoside catabolic process GO:0042454 206 0.026
circadian rhythm GO:0007623 114 0.026
meiotic nuclear division GO:0007126 115 0.026
neuron apoptotic process GO:0051402 142 0.026
head morphogenesis GO:0060323 34 0.026
ventral spinal cord interneuron fate commitment GO:0060579 14 0.026
myoblast differentiation GO:0045445 52 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
cell proliferation in forebrain GO:0021846 30 0.026
muscle cell development GO:0055001 133 0.026
protein ubiquitination GO:0016567 171 0.025
nucleotide catabolic process GO:0009166 217 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
germ cell proliferation GO:0036093 7 0.025
norepinephrine transport GO:0015874 2 0.025
hindlimb morphogenesis GO:0035137 42 0.025
regulation of skeletal muscle fiber development GO:0048742 36 0.025
regulation of cardiac chamber morphogenesis GO:1901219 2 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
regulation of secretion by cell GO:1903530 249 0.025
neuron death GO:0070997 154 0.025
embryonic placenta development GO:0001892 98 0.025
Mouse
fat cell differentiation GO:0045444 160 0.024
regulation of neuron apoptotic process GO:0043523 122 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
cerebral cortex development GO:0021987 86 0.024
midbrain development GO:0030901 35 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
cell migration involved in gastrulation GO:0042074 13 0.024
regulation of secretion GO:0051046 274 0.024
neuromuscular process GO:0050905 99 0.024
cellular response to inorganic substance GO:0071241 37 0.024
eye photoreceptor cell differentiation GO:0001754 41 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
protein localization to nucleus GO:0034504 121 0.024
sensory system development GO:0048880 3 0.024
regulation of tongue muscle cell differentiation GO:2001035 2 0.024
lateral inhibition GO:0046331 1 0.024
regulation of cell growth GO:0001558 91 0.024
astrocyte fate commitment GO:0060018 4 0.023
nucleoside catabolic process GO:0009164 206 0.023
cell growth GO:0016049 130 0.023
brain morphogenesis GO:0048854 32 0.023
carbohydrate metabolic process GO:0005975 230 0.023
mesodermal cell migration GO:0008078 4 0.023
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.023
regulation of auditory receptor cell differentiation GO:0045607 4 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
microtubule based process GO:0007017 236 0.023
regulation of cartilage development GO:0061035 44 0.023
regulation of cell projection organization GO:0031344 206 0.023
negative regulation of bmp signaling pathway GO:0030514 35 0.023
dopaminergic neuron differentiation GO:0071542 14 0.023
nucleoside metabolic process GO:0009116 246 0.023
otic placode formation GO:0043049 1 0.022
cardiac muscle cell differentiation GO:0055007 69 0.022
cerebellum morphogenesis GO:0021587 42 0.022
vagus nerve development GO:0021564 3 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
lens development in camera type eye GO:0002088 62 0.022
mesoderm morphogenesis GO:0048332 64 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
body morphogenesis GO:0010171 45 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
organic anion transport GO:0015711 137 0.022
lung morphogenesis GO:0060425 50 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
morphogenesis of a polarized epithelium GO:0001738 37 0.022
cranial nerve development GO:0021545 41 0.022
lipid homeostasis GO:0055088 63 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
skeletal muscle cell differentiation GO:0035914 66 0.022
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.022
inflammatory response GO:0006954 244 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
regulation of epithelial to mesenchymal transition GO:0010717 22 0.021
branching involved in ureteric bud morphogenesis GO:0001658 56 0.021
development of primary male sexual characteristics GO:0046546 88 0.021
regulation of mesenchymal cell proliferation GO:0010464 37 0.021
endomembrane system organization GO:0010256 147 0.021
blood circulation GO:0008015 195 0.021
Mouse
leukocyte differentiation GO:0002521 342 0.021
Mouse
negative regulation of synapse maturation GO:2000297 2 0.021
regulation of proteolysis GO:0030162 164 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
organophosphate catabolic process GO:0046434 232 0.021
regulation of retina development in camera type eye GO:1902866 3 0.021
multi multicellular organism process GO:0044706 109 0.021
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.021
negative regulation of wnt signaling pathway GO:0030178 73 0.021
regulation of protein processing GO:0070613 96 0.021
embryonic camera type eye development GO:0031076 36 0.021
Mouse
cytokine production GO:0001816 319 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
motor neuron migration GO:0097475 4 0.020
mitral valve morphogenesis GO:0003183 4 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
embryonic heart tube formation GO:0003144 1 0.020
spermatogenesis GO:0007283 284 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
vagus nerve morphogenesis GO:0021644 2 0.020
negative regulation of fat cell differentiation GO:0045599 36 0.020
tongue muscle cell differentiation GO:0035981 2 0.020
nephron tubule morphogenesis GO:0072078 68 0.020
cellular homeostasis GO:0019725 240 0.020
cardiac chamber development GO:0003205 108 0.020
regulation of axon extension GO:0030516 43 0.020
myeloid cell homeostasis GO:0002262 114 0.020
Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.020
germ cell development GO:0007281 185 0.020
regulation of protein stability GO:0031647 52 0.020
notch signaling pathway GO:0007219 71 0.020
visceral motor neuron differentiation GO:0021524 3 0.020
mesonephric epithelium development GO:0072163 94 0.020
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.020
cation transport GO:0006812 399 0.020
organ growth GO:0035265 117 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
regulation of response to wounding GO:1903034 189 0.020
norepinephrine secretion GO:0048243 2 0.019
immune effector process GO:0002252 321 0.019
male sex differentiation GO:0046661 109 0.019
regulation of organelle organization GO:0033043 289 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
regulation of establishment of planar polarity GO:0090175 28 0.019
positive regulation of keratinocyte proliferation GO:0010838 4 0.019
negative regulation of proteolysis GO:0045861 74 0.019
muscle tissue morphogenesis GO:0060415 53 0.019
multicellular organism growth GO:0035264 161 0.019
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.019
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.019
amacrine cell differentiation GO:0035881 5 0.019
nephron epithelium development GO:0072009 92 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.019
artery development GO:0060840 53 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
axis elongation involved in somitogenesis GO:0090245 4 0.018
regulation of osteoblast differentiation GO:0045667 67 0.018
gastrulation GO:0007369 116 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
alcohol metabolic process GO:0006066 116 0.018
mitotic cell cycle GO:0000278 195 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
heart morphogenesis GO:0003007 178 0.018
learning or memory GO:0007611 148 0.018
negative regulation of epithelial cell proliferation GO:0050680 64 0.018
multicellular organismal response to stress GO:0033555 62 0.018
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.018
nitrogen compound transport GO:0071705 271 0.018
mitotic cell cycle process GO:1903047 159 0.018
t cell differentiation GO:0030217 174 0.018
Mouse
positive regulation of muscle cell differentiation GO:0051149 39 0.018
regulation of defense response GO:0031347 233 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
mitochondrion distribution GO:0048311 4 0.018
positive regulation of growth GO:0045927 104 0.018
determination of heart left right asymmetry GO:0061371 48 0.018
neuroblast differentiation GO:0014016 2 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
renal tubule morphogenesis GO:0061333 72 0.018
regulation of mast cell differentiation GO:0060375 3 0.018
axial mesoderm formation GO:0048320 3 0.018
pharynx development GO:0060465 1 0.018
small molecule biosynthetic process GO:0044283 132 0.018
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.018
positive regulation of transferase activity GO:0051347 167 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
cardiac right atrium morphogenesis GO:0003213 3 0.017
sterol metabolic process GO:0016125 58 0.017
skeletal muscle fiber development GO:0048741 58 0.017
face morphogenesis GO:0060325 29 0.017
negative regulation of protein maturation GO:1903318 79 0.017
regulation of lipid transport GO:0032368 36 0.017
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.017
somatic stem cell maintenance GO:0035019 47 0.017
skin development GO:0043588 220 0.017
endoderm development GO:0007492 45 0.017
anion transmembrane transport GO:0098656 71 0.017
mitochondrion organization GO:0007005 134 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
metanephric loop of henle development GO:0072236 4 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
neuron fate specification GO:0048665 30 0.017
metal ion homeostasis GO:0055065 189 0.017
negative regulation of osteoblast differentiation GO:0045668 30 0.017
response to retinoic acid GO:0032526 56 0.017
protein localization to membrane GO:0072657 108 0.017
astrocyte differentiation GO:0048708 43 0.017
protein localization to organelle GO:0033365 185 0.017
inner ear receptor cell development GO:0060119 39 0.017
cell fate specification involved in pattern specification GO:0060573 11 0.017
heart formation GO:0060914 16 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
regulation of protein catabolic process GO:0042176 108 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
central nervous system neuron axonogenesis GO:0021955 28 0.017
nephron development GO:0072006 109 0.017
regulation of gliogenesis GO:0014013 50 0.017
spinal cord patterning GO:0021511 25 0.017
response to transforming growth factor beta GO:0071559 88 0.017
positive regulation of tongue muscle cell differentiation GO:2001037 2 0.016
mesoderm formation GO:0001707 62 0.016
developmental maturation GO:0021700 193 0.016
paraxial mesodermal cell differentiation GO:0048342 2 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
Zebrafish
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
endocrine system development GO:0035270 98 0.016

Sp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
musculoskeletal system disease DOID:17 0 0.027
bone disease DOID:0080001 0 0.026
connective tissue disease DOID:65 0 0.026