Mus musculus

21 known processes

Sp2

Sp2 transcription factor

(Aliases: 4930480I16Rik,mKIAA0048)

Sp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 281 0.075
macromolecule catabolic process GO:0009057 281 0.068
nucleotide metabolic process GO:0009117 332 0.047
small gtpase mediated signal transduction GO:0007264 97 0.045
protein catabolic process GO:0030163 221 0.045
cellular macromolecule catabolic process GO:0044265 206 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
ras protein signal transduction GO:0007265 77 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.040
dna metabolic process GO:0006259 303 0.039
regulation of cellular catabolic process GO:0031329 242 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.038
organic cyclic compound catabolic process GO:1901361 295 0.038
amine metabolic process GO:0009308 45 0.037
negative regulation of molecular function GO:0044092 258 0.036
cellular amine metabolic process GO:0044106 44 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
ubiquitin dependent protein catabolic process GO:0006511 129 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
regulation of organelle organization GO:0033043 289 0.034
cation transport GO:0006812 399 0.034
cellular amino acid metabolic process GO:0006520 103 0.034
apoptotic signaling pathway GO:0097190 306 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
spermatogenesis GO:0007283 284 0.032
aromatic compound catabolic process GO:0019439 286 0.032
cellular ketone metabolic process GO:0042180 84 0.032
nuclear division GO:0000280 158 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.032
immune effector process GO:0002252 321 0.031
oxidation reduction process GO:0055114 342 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
nitrogen compound transport GO:0071705 271 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
axonogenesis GO:0007409 274 0.029
myeloid cell differentiation GO:0030099 233 0.029
Mouse
cellular lipid metabolic process GO:0044255 323 0.028
organelle fission GO:0048285 170 0.028
purine containing compound metabolic process GO:0072521 311 0.028
organonitrogen compound catabolic process GO:1901565 264 0.027
muscle cell differentiation GO:0042692 261 0.027
microtubule based process GO:0007017 236 0.027
inflammatory response GO:0006954 244 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
endocytosis GO:0006897 168 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
meiotic cell cycle GO:0051321 122 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
lipid biosynthetic process GO:0008610 179 0.026
heterocycle catabolic process GO:0046700 280 0.026
muscle tissue development GO:0060537 308 0.026
organelle assembly GO:0070925 177 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.025
response to organonitrogen compound GO:0010243 246 0.025
transmission of nerve impulse GO:0019226 76 0.025
synaptic transmission GO:0007268 329 0.025
forebrain development GO:0030900 302 0.025
male gamete generation GO:0048232 285 0.025
regulation of neuron differentiation GO:0045664 281 0.025
regulation of system process GO:0044057 200 0.024
Mouse
regulation of membrane potential GO:0042391 192 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
membrane organization GO:0061024 245 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
cytoplasmic transport GO:0016482 234 0.024
proteasomal protein catabolic process GO:0010498 98 0.024
cell adhesion GO:0007155 329 0.023
epithelial cell development GO:0002064 159 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
cell division GO:0051301 120 0.023
cellular protein catabolic process GO:0044257 155 0.023
cation transmembrane transport GO:0098655 266 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.023
rho protein signal transduction GO:0007266 32 0.022
lymphocyte differentiation GO:0030098 242 0.022
Mouse
nucleoside catabolic process GO:0009164 206 0.022
nucleotide catabolic process GO:0009166 217 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
regulation of intracellular transport GO:0032386 159 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
regulation of cytokine production GO:0001817 266 0.022
cytokine production GO:0001816 319 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
regulation of cell cycle process GO:0010564 160 0.022
carbohydrate metabolic process GO:0005975 230 0.022
nucleoside metabolic process GO:0009116 246 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
camera type eye development GO:0043010 266 0.021
Mouse
transmembrane transport GO:0055085 412 0.021
regulation of hydrolase activity GO:0051336 246 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
protein ubiquitination GO:0016567 171 0.021
respiratory system development GO:0060541 190 0.021
Mouse
regulation of proteolysis GO:0030162 164 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
development of primary sexual characteristics GO:0045137 143 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
regulation of cell projection organization GO:0031344 206 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
meiotic nuclear division GO:0007126 115 0.020
t cell activation GO:0042110 289 0.020
Mouse
purine nucleoside catabolic process GO:0006152 205 0.020
divalent metal ion transport GO:0070838 172 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
maintenance of location GO:0051235 89 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
blood circulation GO:0008015 195 0.020
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.020
cell type specific apoptotic process GO:0097285 268 0.020
cellular homeostasis GO:0019725 240 0.020
cognition GO:0050890 149 0.020
ribonucleoside catabolic process GO:0042454 206 0.019
mitotic cell cycle process GO:1903047 159 0.019
wnt signaling pathway GO:0016055 188 0.019
regulation of defense response GO:0031347 233 0.019
leukocyte differentiation GO:0002521 342 0.019
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
intracellular mrna localization GO:0008298 4 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
divalent inorganic cation transport GO:0072511 178 0.019
cellular chemical homeostasis GO:0055082 215 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
gonad development GO:0008406 141 0.019
regulation of mapk cascade GO:0043408 248 0.018
organophosphate catabolic process GO:0046434 232 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
rna interference GO:0016246 2 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
respiratory tube development GO:0030323 167 0.018
Mouse
ribonucleotide catabolic process GO:0009261 208 0.018
regulation of protein localization GO:0032880 231 0.018
oocyte axis specification GO:0007309 2 0.018
positive regulation of cell death GO:0010942 224 0.018
organelle localization GO:0051640 179 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
positive regulation of protein modification process GO:0031401 299 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
peptidyl amino acid modification GO:0018193 336 0.017
regulation of cell migration GO:0030334 219 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.017
response to radiation GO:0009314 165 0.017
stem cell differentiation GO:0048863 268 0.017
regulation of cell activation GO:0050865 289 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
germ cell development GO:0007281 185 0.017
response to lipopolysaccharide GO:0032496 128 0.017
protein localization to organelle GO:0033365 185 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
positive regulation of cell development GO:0010720 237 0.016
oocyte construction GO:0007308 2 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
anatomical structure homeostasis GO:0060249 145 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of anatomical structure size GO:0090066 178 0.016
response to organic cyclic compound GO:0014070 198 0.016
negative regulation of nervous system development GO:0051961 156 0.016
rna processing GO:0006396 105 0.016
protein maturation GO:0051604 176 0.016
lateral inhibition GO:0046331 1 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
mitotic cell cycle GO:0000278 195 0.016
rhythmic process GO:0048511 174 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
sequestering of calcium ion GO:0051208 18 0.015
regulation of ion transport GO:0043269 215 0.015
ion transmembrane transport GO:0034220 361 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
striated muscle tissue development GO:0014706 293 0.015
locomotory behavior GO:0007626 195 0.015
multicellular organismal signaling GO:0035637 91 0.015
tube formation GO:0035148 140 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
endomembrane system organization GO:0010256 147 0.015
innate immune response GO:0045087 157 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
chemotaxis GO:0006935 247 0.015
cellular response to lipid GO:0071396 145 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
Mouse
action potential GO:0001508 78 0.015
positive regulation of nervous system development GO:0051962 221 0.015
skeletal muscle organ development GO:0060538 163 0.015
circulatory system process GO:0003013 197 0.015
Mouse
ossification GO:0001503 216 0.015
Mouse
chromatin organization GO:0006325 206 0.015
homeostasis of number of cells GO:0048872 210 0.015
Mouse
glucose homeostasis GO:0042593 128 0.015
embryonic epithelial tube formation GO:0001838 130 0.014
regulation of cellular protein catabolic process GO:1903362 61 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
regulation of secretion GO:0051046 274 0.014
anion transport GO:0006820 177 0.014
negative regulation of immune system process GO:0002683 209 0.014
sensory perception GO:0007600 245 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
regulation of inflammatory response GO:0050727 147 0.014
sequestering of metal ion GO:0051238 19 0.014
regulation of secretion by cell GO:1903530 249 0.014
cellular protein complex assembly GO:0043623 116 0.014
mapk cascade GO:0000165 281 0.014
actin cytoskeleton organization GO:0030036 220 0.014
dephosphorylation GO:0016311 129 0.014
compound eye development GO:0048749 1 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
regulation of protein catabolic process GO:0042176 108 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.014
adaptive immune response GO:0002250 155 0.014
lymphocyte proliferation GO:0046651 164 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
regulation of cellular response to stress GO:0080135 159 0.014
myotube differentiation GO:0014902 105 0.014
cation homeostasis GO:0055080 212 0.014
nuclear import GO:0051170 95 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of hormone levels GO:0010817 211 0.014
lung development GO:0030324 164 0.013
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.013
mrna metabolic process GO:0016071 84 0.013
circadian rhythm GO:0007623 114 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
neural precursor cell proliferation GO:0061351 121 0.013
establishment of organelle localization GO:0051656 122 0.013
myosin filament assembly GO:0031034 2 0.013
covalent chromatin modification GO:0016569 163 0.013
wound healing GO:0042060 157 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
placenta development GO:0001890 140 0.013
Mouse
neuron migration GO:0001764 122 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
renal system development GO:0072001 225 0.013
protein localization to nucleus GO:0034504 121 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
developmental maturation GO:0021700 193 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
carbohydrate homeostasis GO:0033500 128 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
dna repair GO:0006281 107 0.013
negative regulation of cell cycle GO:0045786 123 0.013
glycerolipid metabolic process GO:0046486 122 0.013
protein processing GO:0016485 163 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
myeloid cell homeostasis GO:0002262 114 0.013
Mouse
blood vessel morphogenesis GO:0048514 285 0.013
angiogenesis GO:0001525 201 0.013
translation GO:0006412 93 0.013
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.013
skeletal system development GO:0001501 356 0.013
Mouse
urogenital system development GO:0001655 261 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.012
myosin filament organization GO:0031033 3 0.012
response to peptide GO:1901652 136 0.012
response to acid chemical GO:0001101 111 0.012
peptide transport GO:0015833 133 0.012
hormone secretion GO:0046879 128 0.012
regulation of response to wounding GO:1903034 189 0.012
regulation of homeostatic process GO:0032844 182 0.012
asymmetric stem cell division GO:0098722 3 0.012
plasma membrane organization GO:0007009 90 0.012
leukocyte proliferation GO:0070661 172 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
regulation of transmembrane transport GO:0034762 128 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.012
t cell differentiation GO:0030217 174 0.012
Mouse
response to oxidative stress GO:0006979 123 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of cell growth GO:0001558 91 0.012
male sex differentiation GO:0046661 109 0.012
meiotic cell cycle process GO:1903046 77 0.012
b cell activation GO:0042113 161 0.012
Mouse
negative regulation of cell development GO:0010721 169 0.012
epithelial cell proliferation GO:0050673 174 0.012
regulation of transferase activity GO:0051338 263 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
insulin secretion GO:0030073 89 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
Mouse
regulation of kinase activity GO:0043549 249 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
small molecule biosynthetic process GO:0044283 132 0.012
intracellular protein transport GO:0006886 204 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
calcium ion transport GO:0006816 159 0.012
regulation of chromosome organization GO:0033044 83 0.012
response to inorganic substance GO:0010035 96 0.012
organic acid biosynthetic process GO:0016053 86 0.012
gland development GO:0048732 330 0.012
Mouse
cell activation involved in immune response GO:0002263 126 0.012
learning or memory GO:0007611 148 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
cellularization GO:0007349 1 0.012
alcohol metabolic process GO:0006066 116 0.012
positive regulation of protein transport GO:0051222 93 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
regionalization GO:0003002 337 0.012
Mouse
regulation of protein stability GO:0031647 52 0.012
regulation of protein transport GO:0051223 163 0.012
single organism nuclear import GO:1902593 95 0.012
telencephalon development GO:0021537 186 0.012
positive regulation of organelle organization GO:0010638 128 0.012
regulation of protein kinase activity GO:0045859 232 0.012
blastocyst development GO:0001824 80 0.012
Mouse
oocyte anterior posterior axis specification GO:0007314 2 0.011
cell fate commitment GO:0045165 210 0.011
regulation of ossification GO:0030278 112 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
cellular ion homeostasis GO:0006873 165 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
sulfur compound metabolic process GO:0006790 100 0.011
neuron death GO:0070997 154 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
neural tube development GO:0021915 160 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
regulation of protein maturation GO:1903317 96 0.011
amide transport GO:0042886 138 0.011
kidney development GO:0001822 213 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
positive regulation of cell cycle GO:0045787 92 0.011
stem cell maintenance GO:0019827 130 0.011
positive regulation of immune effector process GO:0002699 107 0.011
stem cell development GO:0048864 219 0.011
skin development GO:0043588 220 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.011
regulation of mrna metabolic process GO:1903311 43 0.011
regulation of protein processing GO:0070613 96 0.011
regulation of cellular component size GO:0032535 121 0.011
mitochondrion organization GO:0007005 134 0.011
cell growth GO:0016049 130 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
neuronal action potential GO:0019228 54 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
response to light stimulus GO:0009416 135 0.011
pole plasm assembly GO:0007315 2 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
limb development GO:0060173 166 0.011
Mouse
interleukin 8 production GO:0032637 4 0.011
regulation of embryonic development GO:0045995 71 0.011
peptidyl serine modification GO:0018209 83 0.011
positive regulation of defense response GO:0031349 124 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
metal ion homeostasis GO:0055065 189 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
multi multicellular organism process GO:0044706 109 0.011
Mouse
glial cell differentiation GO:0010001 131 0.011
negative regulation of organelle organization GO:0010639 90 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
peptide secretion GO:0002790 114 0.011
regulation of t cell activation GO:0050863 170 0.011
actin filament organization GO:0007015 113 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of neuron death GO:1901214 134 0.011
generation of precursor metabolites and energy GO:0006091 103 0.010
spermatid differentiation GO:0048515 115 0.010
pharynx development GO:0060465 1 0.010
spermatid development GO:0007286 108 0.010
signal transduction by p53 class mediator GO:0072331 51 0.010
leukocyte mediated immunity GO:0002443 174 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
negative regulation of protein modification process GO:0031400 163 0.010
neuron apoptotic process GO:0051402 142 0.010
sensory organ morphogenesis GO:0090596 242 0.010
Mouse
response to insulin GO:0032868 100 0.010
erythrocyte differentiation GO:0030218 88 0.010
Mouse
regulation of cell division GO:0051302 76 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
striated muscle cell development GO:0055002 125 0.010
protein targeting GO:0006605 143 0.010
histone modification GO:0016570 159 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
regulation of circadian rhythm GO:0042752 58 0.010
gtp metabolic process GO:0046039 144 0.010
embryonic limb morphogenesis GO:0030326 126 0.010
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.010
regulation of multi organism process GO:0043900 111 0.010
mitochondrion distribution GO:0048311 4 0.010

Sp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.013
organ system cancer DOID:0050686 0 0.012
immune system disease DOID:2914 0 0.011