Mus musculus

74 known processes

Spr

sepiapterin reductase

(Aliases: Gm10328,ENSMUSG00000071345,AA409688)

Spr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.148
purine nucleotide metabolic process GO:0006163 302 0.097
small molecule catabolic process GO:0044282 71 0.092
ribose phosphate metabolic process GO:0019693 291 0.082
cellular lipid metabolic process GO:0044255 323 0.082
purine ribonucleotide metabolic process GO:0009150 290 0.081
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.071
nucleotide metabolic process GO:0009117 332 0.067
cellular amino acid metabolic process GO:0006520 103 0.059
purine nucleoside triphosphate metabolic process GO:0009144 226 0.056
organonitrogen compound catabolic process GO:1901565 264 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.055
mitochondrion organization GO:0007005 134 0.052
intracellular protein transport GO:0006886 204 0.051
purine containing compound metabolic process GO:0072521 311 0.046
heterocycle catabolic process GO:0046700 280 0.044
membrane organization GO:0061024 245 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
nucleoside triphosphate metabolic process GO:0009141 230 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
ribonucleotide metabolic process GO:0009259 291 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.038
purine ribonucleoside catabolic process GO:0046130 205 0.038
ribonucleoside metabolic process GO:0009119 245 0.037
amine metabolic process GO:0009308 45 0.037
ribonucleotide catabolic process GO:0009261 208 0.036
transmembrane transport GO:0055085 412 0.036
atp metabolic process GO:0046034 75 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
cellular ketone metabolic process GO:0042180 84 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
purine nucleotide catabolic process GO:0006195 211 0.034
cation transport GO:0006812 399 0.034
t cell activation GO:0042110 289 0.034
regulation of organelle organization GO:0033043 289 0.034
carboxylic acid catabolic process GO:0046395 51 0.034
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
protein localization to organelle GO:0033365 185 0.032
regulation of purine nucleotide metabolic process GO:1900542 169 0.032
nitrogen compound transport GO:0071705 271 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
nucleotide catabolic process GO:0009166 217 0.030
protein targeting GO:0006605 143 0.030
cellular amine metabolic process GO:0044106 44 0.030
aromatic compound catabolic process GO:0019439 286 0.030
regulation of hormone levels GO:0010817 211 0.029
nucleoside triphosphate catabolic process GO:0009143 205 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
dna metabolic process GO:0006259 303 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
response to organic cyclic compound GO:0014070 198 0.028
organophosphate catabolic process GO:0046434 232 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
amide transport GO:0042886 138 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.027
nucleoside metabolic process GO:0009116 246 0.027
regulation of neuron differentiation GO:0045664 281 0.027
germ cell development GO:0007281 185 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.026
regulation of membrane potential GO:0042391 192 0.026
response to oxidative stress GO:0006979 123 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
skeletal system development GO:0001501 356 0.025
negative regulation of molecular function GO:0044092 258 0.025
regulation of cell activation GO:0050865 289 0.025
cellular lipid catabolic process GO:0044242 52 0.025
nucleoside phosphate catabolic process GO:1901292 222 0.025
ion transmembrane transport GO:0034220 361 0.024
defecation GO:0030421 1 0.024
cellular homeostasis GO:0019725 240 0.024
peptidyl amino acid modification GO:0018193 336 0.024
endomembrane system organization GO:0010256 147 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
regulation of lymphocyte activation GO:0051249 240 0.023
transmission of nerve impulse GO:0019226 76 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
guanosine containing compound catabolic process GO:1901069 144 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
male gamete generation GO:0048232 285 0.023
cytoplasmic transport GO:0016482 234 0.023
response to inorganic substance GO:0010035 96 0.023
organic acid catabolic process GO:0016054 51 0.023
dephosphorylation GO:0016311 129 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
cytokine production GO:0001816 319 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
regulation of protein localization GO:0032880 231 0.022
alcohol metabolic process GO:0006066 116 0.021
regulation of ion transport GO:0043269 215 0.021
response to decreased oxygen levels GO:0036293 59 0.021
macromolecule catabolic process GO:0009057 281 0.021
carbohydrate homeostasis GO:0033500 128 0.021
regulation of feeding behavior GO:0060259 3 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
blood vessel morphogenesis GO:0048514 285 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
gland development GO:0048732 330 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
cell adhesion GO:0007155 329 0.020
digestive system development GO:0055123 200 0.020
cation transmembrane transport GO:0098655 266 0.020
action potential GO:0001508 78 0.020
spermatogenesis GO:0007283 284 0.019
regulation of secretion by cell GO:1903530 249 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
multicellular organismal signaling GO:0035637 91 0.019
leukocyte differentiation GO:0002521 342 0.019
regulation of hydrolase activity GO:0051336 246 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
vesicle localization GO:0051648 86 0.019
gtp catabolic process GO:0006184 143 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
anatomical structure homeostasis GO:0060249 145 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
carbohydrate metabolic process GO:0005975 230 0.018
gliogenesis GO:0042063 141 0.018
cation homeostasis GO:0055080 212 0.018
synaptic transmission GO:0007268 329 0.017
cellular ion homeostasis GO:0006873 165 0.017
positive regulation of protein modification process GO:0031401 299 0.017
regulation of cytokine production GO:0001817 266 0.017
myeloid cell differentiation GO:0030099 233 0.017
cellular response to lipid GO:0071396 145 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
protein localization to mitochondrion GO:0070585 15 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
regulation of secretion GO:0051046 274 0.017
purine containing compound catabolic process GO:0072523 213 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
gtp metabolic process GO:0046039 144 0.017
compound eye development GO:0048749 1 0.017
steroid metabolic process GO:0008202 119 0.017
glucose metabolic process GO:0006006 92 0.016
generation of precursor metabolites and energy GO:0006091 103 0.016
protein oligomerization GO:0051259 67 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
inflammatory response GO:0006954 244 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
neuronal action potential GO:0019228 54 0.016
neural tube development GO:0021915 160 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
lateral inhibition GO:0046331 1 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
respiratory tube development GO:0030323 167 0.016
endocytosis GO:0006897 168 0.015
regulation of lymphocyte proliferation GO:0050670 117 0.015
neuron death GO:0070997 154 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
sensory perception GO:0007600 245 0.015
cellular chemical homeostasis GO:0055082 215 0.015
peptide hormone secretion GO:0030072 109 0.015
sensory organ morphogenesis GO:0090596 242 0.015
ribose phosphate biosynthetic process GO:0046390 59 0.015
succinate transport GO:0015744 1 0.015
rho protein signal transduction GO:0007266 32 0.015
cofactor biosynthetic process GO:0051188 41 0.015
positive regulation of organelle organization GO:0010638 128 0.015
positive regulation of cell death GO:0010942 224 0.015
plasma membrane organization GO:0007009 90 0.015
regulation of protein transport GO:0051223 163 0.015
glucose homeostasis GO:0042593 128 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
sulfur compound metabolic process GO:0006790 100 0.015
peptide secretion GO:0002790 114 0.015
response to radiation GO:0009314 165 0.015
regulation of cellular component size GO:0032535 121 0.015
regulation of t cell activation GO:0050863 170 0.015
muscle system process GO:0003012 141 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.014
muscle cell differentiation GO:0042692 261 0.014
mapk cascade GO:0000165 281 0.014
regulation of response to wounding GO:1903034 189 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
lipid biosynthetic process GO:0008610 179 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of cell motility GO:2000145 236 0.014
renal system development GO:0072001 225 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
single organism nuclear import GO:1902593 95 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
response to oxygen levels GO:0070482 62 0.014
multi multicellular organism process GO:0044706 109 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
response to hypoxia GO:0001666 58 0.014
liver development GO:0001889 66 0.014
regulation of cell projection organization GO:0031344 206 0.013
tissue homeostasis GO:0001894 115 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
cell type specific apoptotic process GO:0097285 268 0.013
urogenital system development GO:0001655 261 0.013
response to organonitrogen compound GO:0010243 246 0.013
immune effector process GO:0002252 321 0.013
organelle assembly GO:0070925 177 0.013
rhythmic process GO:0048511 174 0.013
positive regulation of cell activation GO:0050867 158 0.013
regulation of mapk cascade GO:0043408 248 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
response to starvation GO:0042594 65 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
lymphocyte differentiation GO:0030098 242 0.013
homeostasis of number of cells GO:0048872 210 0.013
organelle localization GO:0051640 179 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
connective tissue development GO:0061448 179 0.013
adult behavior GO:0030534 135 0.013
protein import GO:0017038 101 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
glycerolipid metabolic process GO:0046486 122 0.013
divalent metal ion transport GO:0070838 172 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
nucleoside catabolic process GO:0009164 206 0.013
negative regulation of protein modification process GO:0031400 163 0.013
insulin secretion GO:0030073 89 0.013
calcium ion homeostasis GO:0055074 127 0.012
negative regulation of neuron death GO:1901215 98 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
peptide transport GO:0015833 133 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
pteridine containing compound metabolic process GO:0042558 5 0.012
protein ubiquitination GO:0016567 171 0.012
cellular response to external stimulus GO:0071496 88 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
respiratory system development GO:0060541 190 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of neuron death GO:1901214 134 0.012
lymphocyte proliferation GO:0046651 164 0.012
positive regulation of nervous system development GO:0051962 221 0.012
carboxylic acid transport GO:0046942 100 0.012
protein catabolic process GO:0030163 221 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
leukocyte mediated immunity GO:0002443 174 0.012
histone modification GO:0016570 159 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
regulation of actin filament based process GO:0032970 99 0.012
regulation of neuron projection development GO:0010975 169 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
response to acid chemical GO:0001101 111 0.012
single organism cell adhesion GO:0098602 156 0.012
metal ion homeostasis GO:0055065 189 0.012
locomotory behavior GO:0007626 195 0.011
protein localization to nucleus GO:0034504 121 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
establishment of vesicle localization GO:0051650 81 0.011
positive regulation of growth GO:0045927 104 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
ensheathment of neurons GO:0007272 76 0.011
b cell activation GO:0042113 161 0.011
maintenance of location GO:0051235 89 0.011
positive regulation of secretion GO:0051047 130 0.011
protein maturation GO:0051604 176 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
leukocyte proliferation GO:0070661 172 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
chromatin organization GO:0006325 206 0.011
actin cytoskeleton organization GO:0030036 220 0.011
mitochondrial membrane organization GO:0007006 26 0.011
divalent inorganic cation transport GO:0072511 178 0.011
development of primary sexual characteristics GO:0045137 143 0.011
lung development GO:0030324 164 0.011
angiogenesis GO:0001525 201 0.011
forebrain development GO:0030900 302 0.011
learning or memory GO:0007611 148 0.011
circulatory system process GO:0003013 197 0.011
positive regulation of transferase activity GO:0051347 167 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
protein localization to membrane GO:0072657 108 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
response to extracellular stimulus GO:0009991 127 0.011
sequestering of metal ion GO:0051238 19 0.010
establishment of protein localization to membrane GO:0090150 54 0.010
cofactor metabolic process GO:0051186 80 0.010
cardiac chamber development GO:0003205 108 0.010
monosaccharide metabolic process GO:0005996 106 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
telencephalon development GO:0021537 186 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
response to nutrient levels GO:0031667 109 0.010
lipid modification GO:0030258 65 0.010
regulation of proteolysis GO:0030162 164 0.010
regulation of homeostatic process GO:0032844 182 0.010
cellular respiration GO:0045333 38 0.010
calcium ion transport GO:0006816 159 0.010
cellular response to acid chemical GO:0071229 68 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
covalent chromatin modification GO:0016569 163 0.010
response to drug GO:0042493 75 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
lipid localization GO:0010876 126 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010

Spr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.021
central nervous system disease DOID:331 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011