Mus musculus

0 known processes

Akr1c12

aldo-keto reductase family 1, member C12

(Aliases: AI266976,Akra)

Akr1c12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.324
Mouse
lipid biosynthetic process GO:0008610 179 0.287
Mouse
steroid metabolic process GO:0008202 119 0.221
Mouse
rna splicing GO:0008380 54 0.087
Mouse
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.084
Mouse
rna splicing via transesterification reactions GO:0000375 43 0.080
Mouse
mrna splicing via spliceosome GO:0000398 43 0.073
Mouse
cellular lipid metabolic process GO:0044255 323 0.066
mrna metabolic process GO:0016071 84 0.066
Mouse
regulation of mrna metabolic process GO:1903311 43 0.066
Mouse
steroid biosynthetic process GO:0006694 47 0.064
Mouse
mrna processing GO:0006397 63 0.061
Mouse
negative regulation of mrna processing GO:0050686 12 0.056
Mouse
cellular ketone metabolic process GO:0042180 84 0.051
cellular amino acid metabolic process GO:0006520 103 0.051
regulation of rna splicing GO:0043484 37 0.051
Mouse
rna processing GO:0006396 105 0.050
Mouse
cellular amine metabolic process GO:0044106 44 0.047
monocarboxylic acid metabolic process GO:0032787 191 0.046
sulfur compound metabolic process GO:0006790 100 0.045
amine metabolic process GO:0009308 45 0.045
regulation of mrna splicing via spliceosome GO:0048024 32 0.042
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.042
small molecule biosynthetic process GO:0044283 132 0.037
cation transport GO:0006812 399 0.035
transmembrane transport GO:0055085 412 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
anion transport GO:0006820 177 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
ion transmembrane transport GO:0034220 361 0.033
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.033
Mouse
negative regulation of molecular function GO:0044092 258 0.032
alcohol metabolic process GO:0006066 116 0.030
regulation of hormone levels GO:0010817 211 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
response to organic cyclic compound GO:0014070 198 0.028
cellular alcohol biosynthetic process GO:0044108 3 0.028
response to organonitrogen compound GO:0010243 246 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
monosaccharide metabolic process GO:0005996 106 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
carbohydrate metabolic process GO:0005975 230 0.026
t cell activation GO:0042110 289 0.026
regulation of hydrolase activity GO:0051336 246 0.025
cellular response to lipid GO:0071396 145 0.025
regulation of secretion GO:0051046 274 0.024
cellular alcohol metabolic process GO:0044107 3 0.024
inorganic ion transmembrane transport GO:0098660 234 0.024
nitrogen compound transport GO:0071705 271 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
nucleotide metabolic process GO:0009117 332 0.024
protein maturation GO:0051604 176 0.024
organic acid biosynthetic process GO:0016053 86 0.024
negative regulation of rna splicing GO:0033119 12 0.023
Mouse
regulation of cell activation GO:0050865 289 0.023
fatty acid metabolic process GO:0006631 121 0.023
spermatogenesis GO:0007283 284 0.023
male gamete generation GO:0048232 285 0.023
organonitrogen compound catabolic process GO:1901565 264 0.022
isoprenoid metabolic process GO:0006720 29 0.022
immune effector process GO:0002252 321 0.022
aromatic compound catabolic process GO:0019439 286 0.022
fat soluble vitamin biosynthetic process GO:0042362 4 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
cation transmembrane transport GO:0098655 266 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
negative regulation of mrna metabolic process GO:1903312 13 0.021
Mouse
mapk cascade GO:0000165 281 0.021
sensory perception GO:0007600 245 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
apoptotic signaling pathway GO:0097190 306 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
small molecule catabolic process GO:0044282 71 0.021
organic acid transport GO:0015849 101 0.021
lipid catabolic process GO:0016042 69 0.020
vitamin d3 metabolic process GO:0070640 3 0.020
cellular homeostasis GO:0019725 240 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
terpenoid metabolic process GO:0006721 25 0.020
cellular lipid catabolic process GO:0044242 52 0.020
response to lipopolysaccharide GO:0032496 128 0.020
heterocycle catabolic process GO:0046700 280 0.020
lipid localization GO:0010876 126 0.020
cytokine production GO:0001816 319 0.020
leukocyte differentiation GO:0002521 342 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
purine containing compound metabolic process GO:0072521 311 0.019
calcitriol biosynthetic process from calciol GO:0036378 3 0.019
cell adhesion GO:0007155 329 0.019
cellular chemical homeostasis GO:0055082 215 0.019
glucuronate metabolic process GO:0019585 2 0.019
regulation of mapk cascade GO:0043408 248 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
regulation of transferase activity GO:0051338 263 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
hormone metabolic process GO:0042445 86 0.018
regulation of cytokine production GO:0001817 266 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
inflammatory response GO:0006954 244 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
maintenance of location GO:0051235 89 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
regulation of organelle organization GO:0033043 289 0.017
dephosphorylation GO:0016311 129 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
innate immune response GO:0045087 157 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
cytoplasmic transport GO:0016482 234 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
hormone secretion GO:0046879 128 0.017
positive regulation of protein modification process GO:0031401 299 0.017
blood circulation GO:0008015 195 0.016
regulation of t cell activation GO:0050863 170 0.016
carbohydrate homeostasis GO:0033500 128 0.016
cellular ion homeostasis GO:0006873 165 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
response to acid chemical GO:0001101 111 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
diterpenoid metabolic process GO:0016101 24 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
ribonucleoside metabolic process GO:0009119 245 0.015
regulation of body fluid levels GO:0050878 162 0.015
vitamin d biosynthetic process GO:0042368 3 0.015
membrane organization GO:0061024 245 0.015
divalent inorganic cation transport GO:0072511 178 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
cofactor metabolic process GO:0051186 80 0.015
positive regulation of cell death GO:0010942 224 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
intracellular protein transport GO:0006886 204 0.015
cell type specific apoptotic process GO:0097285 268 0.015
vitamin metabolic process GO:0006766 23 0.015
regulation of membrane potential GO:0042391 192 0.015
myeloid cell differentiation GO:0030099 233 0.015
protein processing GO:0016485 163 0.015
regulation of ion transport GO:0043269 215 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
peptidyl amino acid modification GO:0018193 336 0.015
organic acid catabolic process GO:0016054 51 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
circulatory system process GO:0003013 197 0.015
negative regulation of immune system process GO:0002683 209 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.014
glucose homeostasis GO:0042593 128 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of secretion by cell GO:1903530 249 0.014
protein catabolic process GO:0030163 221 0.014
carboxylic acid transport GO:0046942 100 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
uronic acid metabolic process GO:0006063 2 0.014
divalent metal ion transport GO:0070838 172 0.014
dna metabolic process GO:0006259 303 0.014
progesterone metabolic process GO:0042448 4 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
defense response to bacterium GO:0042742 119 0.014
synaptic transmission GO:0007268 329 0.014
organic anion transport GO:0015711 137 0.014
skeletal system development GO:0001501 356 0.014
regulation of response to wounding GO:1903034 189 0.014
regulation of proteolysis GO:0030162 164 0.014
organophosphate catabolic process GO:0046434 232 0.014
regulation of cell cycle GO:0051726 281 0.014
regulation of homeostatic process GO:0032844 182 0.014
endomembrane system organization GO:0010256 147 0.014
lipid transport GO:0006869 98 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
inter male aggressive behavior GO:0002121 3 0.014
negative regulation of phospholipase activity GO:0010519 4 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
nucleotide catabolic process GO:0009166 217 0.014
secondary alcohol metabolic process GO:1902652 3 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.013
nucleoside metabolic process GO:0009116 246 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
glycoprotein metabolic process GO:0009100 116 0.013
glutathione metabolic process GO:0006749 16 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
lymphocyte differentiation GO:0030098 242 0.013
organelle fission GO:0048285 170 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
purine containing compound catabolic process GO:0072523 213 0.013
nuclear division GO:0000280 158 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
fatty acid derivative metabolic process GO:1901568 33 0.013
regulation of protein kinase activity GO:0045859 232 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of system process GO:0044057 200 0.013
peptide transport GO:0015833 133 0.013
glycerolipid metabolic process GO:0046486 122 0.013
cellular amide metabolic process GO:0043603 58 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
metal ion homeostasis GO:0055065 189 0.013
amide transport GO:0042886 138 0.013
response to inorganic substance GO:0010035 96 0.013
macromolecule catabolic process GO:0009057 281 0.013
homeostasis of number of cells GO:0048872 210 0.013
placenta development GO:0001890 140 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of peptidase activity GO:0052547 96 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
compound eye development GO:0048749 1 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of kinase activity GO:0043549 249 0.012
leukocyte mediated immunity GO:0002443 174 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
leukocyte proliferation GO:0070661 172 0.012
activation of immune response GO:0002253 138 0.012
germ cell development GO:0007281 185 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
protein localization to organelle GO:0033365 185 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
regulation of anatomical structure size GO:0090066 178 0.012
regulation of defense response GO:0031347 233 0.012
anatomical structure homeostasis GO:0060249 145 0.012
coenzyme metabolic process GO:0006732 52 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
ras protein signal transduction GO:0007265 77 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of protein localization GO:0032880 231 0.012
wound healing GO:0042060 157 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
response to extracellular stimulus GO:0009991 127 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
sequestering of calcium ion GO:0051208 18 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.011
gland development GO:0048732 330 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
locomotory behavior GO:0007626 195 0.011
regulation of protein complex assembly GO:0043254 83 0.011
nucleoside catabolic process GO:0009164 206 0.011
response to nutrient levels GO:0031667 109 0.011
cation homeostasis GO:0055080 212 0.011
calcium ion transport GO:0006816 159 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
nadph regeneration GO:0006740 2 0.011
microtubule based process GO:0007017 236 0.011
oxidative demethylation GO:0070989 1 0.011
response to oxidative stress GO:0006979 123 0.011
sequestering of metal ion GO:0051238 19 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
camera type eye development GO:0043010 266 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of transmembrane transport GO:0034762 128 0.011
response to peptide hormone GO:0043434 127 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of cell motility GO:2000145 236 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
calcium ion homeostasis GO:0055074 127 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of cell projection organization GO:0031344 206 0.011
ear development GO:0043583 200 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
epithelial cell development GO:0002064 159 0.011
naphthalene containing compound metabolic process GO:0090420 1 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
anion transmembrane transport GO:0098656 71 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
positive regulation of cell development GO:0010720 237 0.011
negative regulation of hormone metabolic process GO:0032351 4 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
developmental maturation GO:0021700 193 0.011
t cell differentiation GO:0030217 174 0.011
response to peptide GO:1901652 136 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
regulation of feeding behavior GO:0060259 3 0.011
organelle localization GO:0051640 179 0.011
peptide hormone secretion GO:0030072 109 0.011
cellular metal ion homeostasis GO:0006875 151 0.010
positive regulation of cell activation GO:0050867 158 0.010
alpha amino acid metabolic process GO:1901605 59 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
fat cell differentiation GO:0045444 160 0.010
positive regulation of secretion GO:0051047 130 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
peptide secretion GO:0002790 114 0.010
respiratory tube development GO:0030323 167 0.010
alcohol biosynthetic process GO:0046165 43 0.010
regulation of protein transport GO:0051223 163 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
positive regulation of transferase activity GO:0051347 167 0.010
rho protein signal transduction GO:0007266 32 0.010
icosanoid metabolic process GO:0006690 33 0.010
regulation of neuron differentiation GO:0045664 281 0.010
interleukin 8 production GO:0032637 4 0.010
glucose metabolic process GO:0006006 92 0.010
regulation of intracellular transport GO:0032386 159 0.010
methylation GO:0032259 134 0.010
mitotic cell cycle GO:0000278 195 0.010
sensory organ morphogenesis GO:0090596 242 0.010
protein targeting GO:0006605 143 0.010
fertilization GO:0009566 127 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
nuclear transport GO:0051169 139 0.010
positive regulation of kinase activity GO:0033674 155 0.010
defense response to other organism GO:0098542 197 0.010
epidermis development GO:0008544 187 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
polyamine catabolic process GO:0006598 2 0.010

Akr1c12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.032
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
inherited metabolic disorder DOID:655 0 0.022
musculoskeletal system disease DOID:17 0 0.018
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.015
cancer DOID:162 0 0.015
connective tissue disease DOID:65 0 0.014
sensory system disease DOID:0050155 0 0.012
immune system disease DOID:2914 0 0.012
bone disease DOID:0080001 0 0.011
cardiovascular system disease DOID:1287 0 0.011
central nervous system disease DOID:331 0 0.010