Mus musculus

13 known processes

Ifih1

interferon induced with helicase C domain 1

(Aliases: MDA5,9130009C22Rik,MGC90959,Helicard,Hlcd)

Ifih1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 197 0.945
Mouse
regulation of defense response to virus by host GO:0050691 8 0.856
cellular response to interferon beta GO:0035458 21 0.853
regulation of interferon alpha production GO:0032647 5 0.840
Human
positive regulation of interferon alpha production GO:0032727 4 0.773
Human
interspecies interaction between organisms GO:0044419 83 0.699
Mouse
cellular response to interferon alpha GO:0035457 4 0.688
viral life cycle GO:0019058 36 0.686
Mouse
innate immune response GO:0045087 157 0.659
negative regulation of viral process GO:0048525 23 0.579
defense response to bacterium GO:0042742 119 0.579
type i interferon production GO:0032606 29 0.546
Human Mouse
regulation of multi organism process GO:0043900 111 0.530
Mouse
response to interferon beta GO:0035456 22 0.524
immune effector process GO:0002252 321 0.522
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.480
positive regulation of viral genome replication GO:0045070 2 0.458
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.414
Mouse
regulation of response to biotic stimulus GO:0002831 38 0.393
Mouse
negative regulation of interferon alpha production GO:0032687 1 0.382
viral process GO:0016032 41 0.368
Mouse
macromolecule catabolic process GO:0009057 281 0.347
response to organic cyclic compound GO:0014070 198 0.343
Mouse Worm
response to stilbenoid GO:0035634 22 0.341
activation of innate immune response GO:0002218 56 0.341
Mouse
negative regulation of viral genome replication GO:0045071 10 0.315
regulation of protein transport GO:0051223 163 0.310
protein modification by small protein conjugation GO:0032446 187 0.306
Human
regulation of defense response GO:0031347 233 0.303
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.300
Mouse
regulation of cytokine production GO:0001817 266 0.296
Human Mouse
response to interferon alpha GO:0035455 7 0.285
purine containing compound metabolic process GO:0072521 311 0.275
Worm
defense response to virus GO:0051607 68 0.271
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.267
Worm
regulation of viral release from host cell GO:1902186 6 0.259
cytokine production GO:0001816 319 0.257
Human Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.251
Human
response to lipopolysaccharide GO:0032496 128 0.249
cellular response to cytokine stimulus GO:0071345 189 0.246
cellular response to lipid GO:0071396 145 0.246
regulation of intracellular transport GO:0032386 159 0.238
negative regulation of cytokine production GO:0001818 84 0.224
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.216
Worm
regulation of rig i signaling pathway GO:0039535 2 0.214
Mouse
negative regulation of cell proliferation GO:0008285 296 0.212
Mouse
intracellular protein transport GO:0006886 204 0.212
purine ribonucleotide catabolic process GO:0009154 208 0.212
Worm
autophagy GO:0006914 45 0.212
adhesion of symbiont to host GO:0044406 8 0.203
nucleoside phosphate metabolic process GO:0006753 338 0.194
Worm
regulation of defense response to bacterium GO:1900424 3 0.183
cytoplasmic transport GO:0016482 234 0.183
rig i signaling pathway GO:0039529 4 0.177
Mouse
heterocycle catabolic process GO:0046700 280 0.171
Worm
regulation of viral genome replication GO:0045069 13 0.166
Mouse
regulation of protein localization GO:0032880 231 0.158
negative regulation of defense response to virus by host GO:0050689 1 0.153
negative regulation of molecular function GO:0044092 258 0.150
nucleoside catabolic process GO:0009164 206 0.147
Worm
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.143
Mouse
protein import GO:0017038 101 0.141
organic cyclic compound catabolic process GO:1901361 295 0.133
Worm
protein localization to nucleus GO:0034504 121 0.127
pyroptosis GO:0070269 8 0.126
purine ribonucleoside metabolic process GO:0046128 241 0.124
Worm
regulation of defense response to virus GO:0050688 18 0.124
Mouse
purine containing compound catabolic process GO:0072523 213 0.120
Worm
positive regulation of viral entry into host cell GO:0046598 3 0.118
interaction with host GO:0051701 22 0.116
negative regulation of hydrolase activity GO:0051346 71 0.115
purine nucleoside catabolic process GO:0006152 205 0.114
Worm
nucleocytoplasmic transport GO:0006913 139 0.113
negative regulation of multi organism process GO:0043901 68 0.111
Mouse
interferon beta production GO:0032608 16 0.110
Human Mouse
organophosphate catabolic process GO:0046434 232 0.107
Worm
nucleoside triphosphate catabolic process GO:0009143 205 0.106
Worm
cellular response to type i interferon GO:0071357 10 0.104
single organism nuclear import GO:1902593 95 0.104
aromatic compound catabolic process GO:0019439 286 0.103
Worm
myeloid leukocyte differentiation GO:0002573 119 0.103
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.101
regulation of establishment of protein localization GO:0070201 181 0.101
negative regulation of viral release from host cell GO:1902187 6 0.101
regulation of type i interferon production GO:0032479 22 0.100
Human Mouse
purine nucleoside metabolic process GO:0042278 241 0.099
Worm
regulation of cytoplasmic transport GO:1903649 112 0.099
response to protozoan GO:0001562 28 0.099
protein catabolic process GO:0030163 221 0.098
toll like receptor 7 signaling pathway GO:0034154 4 0.097
protein import into nucleus GO:0006606 95 0.096
regulation of protein targeting GO:1903533 61 0.096
viral gene expression GO:0019080 3 0.096
regulation of actin nucleation GO:0051125 4 0.091
glycosyl compound metabolic process GO:1901657 246 0.091
Worm
defense response to protozoan GO:0042832 25 0.087
cellular response to molecule of bacterial origin GO:0071219 83 0.086
movement in host environment GO:0052126 15 0.081
negative regulation of cytoplasmic transport GO:1903650 29 0.080
response to molecule of bacterial origin GO:0002237 143 0.079
nucleoside metabolic process GO:0009116 246 0.079
Worm
interferon alpha production GO:0032607 7 0.079
Human
ribose phosphate metabolic process GO:0019693 291 0.078
Worm
negative regulation of protein metabolic process GO:0051248 282 0.077
nucleobase containing small molecule metabolic process GO:0055086 352 0.076
Worm
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.076
organonitrogen compound catabolic process GO:1901565 264 0.075
Worm
nucleoside triphosphate metabolic process GO:0009141 230 0.074
Worm
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.074
positive regulation of viral process GO:0048524 5 0.074
regulation of homeostatic process GO:0032844 182 0.072
isg15 protein conjugation GO:0032020 4 0.072
glycosyl compound catabolic process GO:1901658 206 0.071
Worm
negative regulation of protein ubiquitination GO:0031397 19 0.065
regulation of protein localization to nucleus GO:1900180 60 0.065
negative regulation of phosphate metabolic process GO:0045936 184 0.062
regulation of intracellular protein transport GO:0033157 82 0.062
negative regulation of intracellular protein transport GO:0090317 27 0.061
regulation of protein binding GO:0043393 60 0.060
cellular response to interferon gamma GO:0071346 25 0.059
nucleotide catabolic process GO:0009166 217 0.059
Worm
protein ubiquitination GO:0016567 171 0.059
cell type specific apoptotic process GO:0097285 268 0.059
Mouse
defense response to gram positive bacterium GO:0050830 50 0.059
negative regulation of protein phosphorylation GO:0001933 126 0.059
positive regulation of rig i signaling pathway GO:1900246 1 0.058
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.058
Worm
response to interferon gamma GO:0034341 34 0.057
nucleotide metabolic process GO:0009117 332 0.056
Worm
membrane fusion GO:0061025 38 0.055
hematopoietic progenitor cell differentiation GO:0002244 143 0.055
homeostasis of number of cells GO:0048872 210 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
Worm
purine nucleotide metabolic process GO:0006163 302 0.054
Worm
positive regulation of defense response GO:0031349 124 0.054
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.054
Worm
regulation of cellular catabolic process GO:0031329 242 0.054
cellular macromolecule catabolic process GO:0044265 206 0.052
negative regulation of immune effector process GO:0002698 55 0.051
Mouse
inflammatory response GO:0006954 244 0.051
nuclear transport GO:0051169 139 0.050
response to dsrna GO:0043331 30 0.048
Mouse Worm
positive regulation of programmed cell death GO:0043068 218 0.046
ribonucleoside catabolic process GO:0042454 206 0.045
Worm
leukocyte mediated immunity GO:0002443 174 0.045
positive regulation of mapk cascade GO:0043410 170 0.045
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.043
purine ribonucleotide metabolic process GO:0009150 290 0.043
Worm
regulation of autophagy GO:0010506 30 0.042
regulation of protein import into nucleus GO:0042306 52 0.042
negative regulation of protein transport GO:0051224 46 0.042
t helper 2 cell cytokine production GO:0035745 4 0.041
protein localization to organelle GO:0033365 185 0.040
purine nucleotide catabolic process GO:0006195 211 0.040
Worm
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.040
antimicrobial peptide production GO:0002775 2 0.040
positive regulation of innate immune response GO:0045089 80 0.039
Mouse
regulation of secretion by cell GO:1903530 249 0.039
positive regulation of cytokine production GO:0001819 174 0.038
Human Mouse
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.038
cellular metal ion homeostasis GO:0006875 151 0.038
regulation of organelle organization GO:0033043 289 0.038
regulation of response to wounding GO:1903034 189 0.037
ribonucleotide metabolic process GO:0009259 291 0.037
Worm
nuclear import GO:0051170 95 0.036
negative regulation of intracellular transport GO:0032387 38 0.036
t cell differentiation GO:0030217 174 0.036
skin development GO:0043588 220 0.036
Mouse
entry into host GO:0044409 15 0.036
response to phenylpropanoid GO:0080184 22 0.036
entry into host cell GO:0030260 15 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
Worm
protein maturation GO:0051604 176 0.035
regulation of secretion GO:0051046 274 0.035
regulation of nucleocytoplasmic transport GO:0046822 73 0.034
vesicle organization GO:0016050 60 0.034
negative regulation of viral entry into host cell GO:0046597 10 0.034
antimicrobial peptide biosynthetic process GO:0002777 2 0.034
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.033
regulation of binding GO:0051098 111 0.033
cellular response to organic cyclic compound GO:0071407 87 0.033
Mouse Worm
gtp metabolic process GO:0046039 144 0.032
guanosine containing compound metabolic process GO:1901068 144 0.032
myeloid cell homeostasis GO:0002262 114 0.032
cell adhesion GO:0007155 329 0.032
regulation of antimicrobial humoral response GO:0002759 3 0.031
regulation of interleukin 1 alpha production GO:0032650 4 0.031
organophosphate biosynthetic process GO:0090407 122 0.031
regulation of protein ubiquitination GO:0031396 52 0.031
regulation of adaptive immune response GO:0002819 90 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.031
gtp catabolic process GO:0006184 143 0.030
maintenance of location GO:0051235 89 0.030
protein targeting GO:0006605 143 0.030
negative regulation of protein binding GO:0032091 17 0.030
cellular amine metabolic process GO:0044106 44 0.030
negative regulation of protein modification process GO:0031400 163 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
positive regulation of immune effector process GO:0002699 107 0.029
Mouse
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.029
epithelial tube morphogenesis GO:0060562 303 0.029
Mouse
regulation of toll like receptor signaling pathway GO:0034121 20 0.028
germ cell development GO:0007281 185 0.028
cellular response to exogenous dsrna GO:0071360 5 0.028
compound eye development GO:0048749 1 0.028
negative regulation of phosphorylation GO:0042326 166 0.028
neuronal action potential GO:0019228 54 0.028
regulation of endopeptidase activity GO:0052548 89 0.028
positive regulation of actin nucleation GO:0051127 3 0.028
rhythmic process GO:0048511 174 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
Worm
negative regulation of molecular function in other organism involved in symbiotic interaction GO:0052204 1 0.028
purine ribonucleoside catabolic process GO:0046130 205 0.028
Worm
antibacterial peptide production GO:0002778 2 0.027
regulation of interferon beta biosynthetic process GO:0045357 4 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
regulation of proteolysis GO:0030162 164 0.027
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.027
Mouse
cellular ketone metabolic process GO:0042180 84 0.027
regulation of cytoskeleton organization GO:0051493 122 0.026
circadian rhythm GO:0007623 114 0.026
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.026
negative regulation of immune system process GO:0002683 209 0.026
Mouse
metal ion homeostasis GO:0055065 189 0.026
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.025
defense response to gram negative bacterium GO:0050829 28 0.025
cellular amino acid metabolic process GO:0006520 103 0.025
histone acetylation GO:0016573 41 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
mitotic cell cycle process GO:1903047 159 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
Worm
positive regulation of protein transport GO:0051222 93 0.024
positive regulation of cell death GO:0010942 224 0.024
cellular response to lipopolysaccharide GO:0071222 77 0.024
regulation of leukocyte apoptotic process GO:2000106 56 0.024
interferon beta biosynthetic process GO:0045350 4 0.024
blood vessel morphogenesis GO:0048514 285 0.024
Mouse
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.024
negative regulation of binding GO:0051100 39 0.024
protein processing GO:0016485 163 0.024
t cell activation GO:0042110 289 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
apoptotic signaling pathway GO:0097190 306 0.023
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.023
membrane organization GO:0061024 245 0.023
positive regulation of intracellular transport GO:0032388 70 0.023
regulation of protein catabolic process GO:0042176 108 0.022
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.022
cation transport GO:0006812 399 0.022
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.022
response to organonitrogen compound GO:0010243 246 0.021
cellular homeostasis GO:0019725 240 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
Worm
alpha beta t cell activation GO:0046631 91 0.021
production of molecular mediator of immune response GO:0002440 103 0.021
spermatogenesis GO:0007283 284 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
Worm
stem cell differentiation GO:0048863 268 0.021
Mouse
viral genome replication GO:0019079 17 0.020
Mouse
pyrimidine containing compound catabolic process GO:0072529 3 0.020
chromatin organization GO:0006325 206 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
modification by symbiont of host morphology or physiology GO:0044003 4 0.020
acute inflammatory response GO:0002526 41 0.020
positive regulation of antimicrobial humoral response GO:0002760 2 0.020
regulation of cell cycle GO:0051726 281 0.020
Mouse
response to type i interferon GO:0034340 12 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
developmental maturation GO:0021700 193 0.019
microtubule based process GO:0007017 236 0.019
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.019
schwann cell proliferation GO:0014010 2 0.019
Mouse
hair follicle cell proliferation GO:0071335 3 0.019
Mouse
calcium ion homeostasis GO:0055074 127 0.019
carbohydrate metabolic process GO:0005975 230 0.019
protein secretion GO:0009306 111 0.019
cellular protein catabolic process GO:0044257 155 0.018
cell fate commitment GO:0045165 210 0.018
ossification GO:0001503 216 0.018
negative regulation of protein import into nucleus GO:0042308 21 0.018
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.018
sensory perception GO:0007600 245 0.018
regulation of peptidase activity GO:0052547 96 0.018
response to glucocorticoid GO:0051384 20 0.018
regulation of hydrolase activity GO:0051336 246 0.018
male gamete generation GO:0048232 285 0.018
positive regulation of organelle organization GO:0010638 128 0.018
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.018
regulation of cell activation GO:0050865 289 0.018
interleukin 8 production GO:0032637 4 0.018
lung development GO:0030324 164 0.017
Mouse
negative regulation of defense response GO:0031348 77 0.017
Mouse
regulation of interferon beta production GO:0032648 13 0.017
Human Mouse
guanosine containing compound catabolic process GO:1901069 144 0.017
positive regulation of protein complex assembly GO:0031334 45 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
regulation of viral entry into host cell GO:0046596 12 0.017
regulation of protein processing GO:0070613 96 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
endocytosis GO:0006897 168 0.017
protein oligomerization GO:0051259 67 0.017
positive regulation of potassium ion transport GO:0043268 3 0.017
regulation of cytokine biosynthetic process GO:0042035 59 0.017
sequestering of calcium ion GO:0051208 18 0.017
activation of immune response GO:0002253 138 0.017
Mouse
modulation by virus of host morphology or physiology GO:0019048 3 0.017
regulation of interleukin 12 production GO:0032655 30 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
Mouse
divalent inorganic cation transport GO:0072511 178 0.016
leukocyte mediated cytotoxicity GO:0001909 62 0.016
sequestering of metal ion GO:0051238 19 0.016
cell division GO:0051301 120 0.016
Mouse
regulation of neuron differentiation GO:0045664 281 0.016
Mouse
killing by host of symbiont cells GO:0051873 11 0.016
organelle localization GO:0051640 179 0.016
mda 5 signaling pathway GO:0039530 1 0.016
Mouse
citrate metabolic process GO:0006101 3 0.016
epithelial cell proliferation GO:0050673 174 0.016
regulation of production of molecular mediator of immune response GO:0002700 65 0.016
epidermis development GO:0008544 187 0.016
Mouse
regulation of antimicrobial peptide production GO:0002784 1 0.016
lymphocyte differentiation GO:0030098 242 0.016
gene silencing by mirna GO:0035195 10 0.016
Mouse
establishment of protein localization to organelle GO:0072594 118 0.016
leukocyte differentiation GO:0002521 342 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.015
erythrocyte differentiation GO:0030218 88 0.015
limb morphogenesis GO:0035108 149 0.015
Mouse
peptidyl amino acid modification GO:0018193 336 0.015
cellular lipid metabolic process GO:0044255 323 0.015
transmembrane transport GO:0055085 412 0.015
negative regulation of protein processing GO:0010955 79 0.015
mapk cascade GO:0000165 281 0.015
fatty acid metabolic process GO:0006631 121 0.015
negative regulation of secretion by cell GO:1903531 54 0.015
negative regulation of protein localization to nucleus GO:1900181 23 0.015
alpha beta t cell differentiation GO:0046632 69 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
endomembrane system organization GO:0010256 147 0.015
regulation of body fluid levels GO:0050878 162 0.015
regulation of mapk cascade GO:0043408 248 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
Mouse Worm
covalent chromatin modification GO:0016569 163 0.014
leukocyte homeostasis GO:0001776 79 0.014
appendage morphogenesis GO:0035107 149 0.014
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
regulation of viral transcription GO:0046782 3 0.014
immune response activating signal transduction GO:0002757 116 0.014
Mouse
positive regulation of protein catabolic process GO:0045732 60 0.014
positive regulation of interleukin 1 alpha production GO:0032730 4 0.014
gliogenesis GO:0042063 141 0.014
Mouse
dendrite development GO:0016358 115 0.014
anion transport GO:0006820 177 0.014
response to unfolded protein GO:0006986 21 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
cellularization GO:0007349 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
natural killer cell proliferation GO:0001787 3 0.014
membrane depolarization GO:0051899 64 0.014
interleukin 6 production GO:0032635 58 0.014
cation homeostasis GO:0055080 212 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.014
respiratory tube development GO:0030323 167 0.014
Mouse
syncytium formation by plasma membrane fusion GO:0000768 42 0.014
dna metabolic process GO:0006259 303 0.013
regulation of transferase activity GO:0051338 263 0.013
atp metabolic process GO:0046034 75 0.013
Worm
cellular amide metabolic process GO:0043603 58 0.013
cellular response to dsrna GO:0071359 12 0.013
Mouse Worm
mitotic cell cycle GO:0000278 195 0.013
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of defense response to fungus GO:1900150 1 0.013
mast cell proliferation GO:0070662 4 0.013
regulation of b cell activation GO:0050864 81 0.013
oogenesis GO:0048477 56 0.013
actin cytoskeleton organization GO:0030036 220 0.013
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.013
protein acylation GO:0043543 64 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
adaptive immune response GO:0002250 155 0.013
cellular response to acid chemical GO:0071229 68 0.013
b cell activation GO:0042113 161 0.013
myeloid cell differentiation GO:0030099 233 0.013
digestive system development GO:0055123 200 0.013
Mouse
spermatid differentiation GO:0048515 115 0.013
dna repair GO:0006281 107 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
Worm
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.012
regulation of lymphocyte apoptotic process GO:0070228 41 0.012
regulation of interleukin 6 production GO:0032675 55 0.012
regulation of system process GO:0044057 200 0.012
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
Worm
regulation of cell migration GO:0030334 219 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
Worm
positive regulation of proteolysis GO:0045862 85 0.012
regulation of t cell activation GO:0050863 170 0.012
tissue homeostasis GO:0001894 115 0.012
b cell mediated immunity GO:0019724 71 0.012
extracellular matrix organization GO:0030198 147 0.012
response to nutrient levels GO:0031667 109 0.012
b cell activation involved in immune response GO:0002312 50 0.012
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.012
Mouse
double strand break repair GO:0006302 48 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
negative regulation of proteolysis GO:0045861 74 0.012
regionalization GO:0003002 337 0.012
digestion GO:0007586 40 0.012
cellular ion homeostasis GO:0006873 165 0.012
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
t helper 17 cell lineage commitment GO:0072540 4 0.012
interleukin 1 alpha secretion GO:0050703 3 0.012
regulation of protein maturation GO:1903317 96 0.012
viral release from host cell GO:0019076 6 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
Worm
negative regulation of secretion GO:0051048 61 0.012
urogenital system development GO:0001655 261 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
negative regulation of defense response to virus GO:0050687 6 0.011
Mouse
divalent metal ion transport GO:0070838 172 0.011
neuron death GO:0070997 154 0.011
leukocyte proliferation GO:0070661 172 0.011
negative regulation of protein maturation GO:1903318 79 0.011
regulation of ossification GO:0030278 112 0.011
positive regulation of protein modification process GO:0031401 299 0.011
negative regulation of cell activation GO:0050866 111 0.011
positive regulation of secretion GO:0051047 130 0.011
synaptic transmission GO:0007268 329 0.011
negative regulation of peptidase activity GO:0010466 46 0.011
nitrogen compound transport GO:0071705 271 0.011
positive regulation of myeloid cell differentiation GO:0045639 43 0.011
hatching GO:0035188 4 0.011
Worm
peripheral nervous system development GO:0007422 53 0.011
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
translation GO:0006412 93 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
viral transcription GO:0019083 3 0.011
valine metabolic process GO:0006573 4 0.011
anatomical structure homeostasis GO:0060249 145 0.011
positive regulation of defense response to bacterium GO:1900426 1 0.011
positive regulation of cell cycle GO:0045787 92 0.011
interferon alpha biosynthetic process GO:0045349 1 0.011
cell killing GO:0001906 67 0.011
regulation of actin filament based process GO:0032970 99 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
atp catabolic process GO:0006200 55 0.011
Worm
renal system development GO:0072001 225 0.011
amine metabolic process GO:0009308 45 0.011
multi multicellular organism process GO:0044706 109 0.010
regulation of neuron death GO:1901214 134 0.010
spleen development GO:0048536 39 0.010
Mouse
cell recognition GO:0008037 83 0.010
sensory perception of mechanical stimulus GO:0050954 107 0.010
regulation of cellular component size GO:0032535 121 0.010
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.010
positive regulation of cytoplasmic transport GO:1903651 40 0.010
rna processing GO:0006396 105 0.010
Mouse Worm
myeloid leukocyte activation GO:0002274 83 0.010
tube formation GO:0035148 140 0.010
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.010
regulation of circadian rhythm GO:0042752 58 0.010
cellular chemical homeostasis GO:0055082 215 0.010
gland development GO:0048732 330 0.010
t cell lineage commitment GO:0002360 13 0.010
pre mirna processing GO:0031054 3 0.010
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.010
glial cell apoptotic process GO:0034349 3 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
positive regulation of antimicrobial peptide production GO:0002225 1 0.010
regulation of inflammatory response GO:0050727 147 0.010
cellular protein complex assembly GO:0043623 116 0.010

Ifih1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.015
disease of metabolism DOID:0014667 0 0.014
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011