Mus musculus

42 known processes

Spaca1

sperm acrosome associated 1

(Aliases: 4930540L03Rik,1700124L11Rik)

Spaca1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
amine metabolic process GO:0009308 45 0.038
male gamete generation GO:0048232 285 0.038
cellular ketone metabolic process GO:0042180 84 0.037
transmembrane transport GO:0055085 412 0.034
cellular amine metabolic process GO:0044106 44 0.034
negative regulation of protein metabolic process GO:0051248 282 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
ion transmembrane transport GO:0034220 361 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
negative regulation of molecular function GO:0044092 258 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
dna metabolic process GO:0006259 303 0.028
anion transport GO:0006820 177 0.027
meiotic cell cycle GO:0051321 122 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
nucleotide metabolic process GO:0009117 332 0.026
cation transport GO:0006812 399 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
ribose phosphate metabolic process GO:0019693 291 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
ribonucleotide metabolic process GO:0009259 291 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
oxidation reduction process GO:0055114 342 0.023
peptidyl amino acid modification GO:0018193 336 0.023
regulation of membrane potential GO:0042391 192 0.023
protein catabolic process GO:0030163 221 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
protein ubiquitination GO:0016567 171 0.022
macromolecule catabolic process GO:0009057 281 0.022
purine containing compound metabolic process GO:0072521 311 0.022
aromatic compound catabolic process GO:0019439 286 0.022
nucleoside metabolic process GO:0009116 246 0.022
regulation of cell activation GO:0050865 289 0.022
regulation of organelle organization GO:0033043 289 0.021
regulation of transferase activity GO:0051338 263 0.021
cation transmembrane transport GO:0098655 266 0.021
membrane organization GO:0061024 245 0.021
apoptotic signaling pathway GO:0097190 306 0.020
organelle fission GO:0048285 170 0.020
sensory perception GO:0007600 245 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
cellular lipid metabolic process GO:0044255 323 0.020
ras protein signal transduction GO:0007265 77 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.019
meiotic nuclear division GO:0007126 115 0.019
regulation of neuron differentiation GO:0045664 281 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
fertilization GO:0009566 127 0.019
male meiosis GO:0007140 37 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
positive regulation of protein modification process GO:0031401 299 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
response to organonitrogen compound GO:0010243 246 0.019
chromosome organization involved in meiosis GO:0070192 39 0.019
microtubule based process GO:0007017 236 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
organic anion transport GO:0015711 137 0.018
cytokine production GO:0001816 319 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
carbohydrate metabolic process GO:0005975 230 0.018
heterocycle catabolic process GO:0046700 280 0.018
positive regulation of nervous system development GO:0051962 221 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
immune effector process GO:0002252 321 0.018
organonitrogen compound catabolic process GO:1901565 264 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
nitrogen compound transport GO:0071705 271 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
cellular homeostasis GO:0019725 240 0.017
regulation of secretion by cell GO:1903530 249 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
camera type eye development GO:0043010 266 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
regulation of cytokine production GO:0001817 266 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.016
nuclear division GO:0000280 158 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
nucleoside catabolic process GO:0009164 206 0.016
spermatid development GO:0007286 108 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
negative regulation of protein modification process GO:0031400 163 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
regulation of cell cycle GO:0051726 281 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of response to wounding GO:1903034 189 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
regulation of system process GO:0044057 200 0.016
regulation of secretion GO:0051046 274 0.016
cytoplasmic transport GO:0016482 234 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
purine containing compound catabolic process GO:0072523 213 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
inflammatory response GO:0006954 244 0.016
negative regulation of immune system process GO:0002683 209 0.016
protein maturation GO:0051604 176 0.016
meiosis i GO:0007127 60 0.016
regulation of defense response GO:0031347 233 0.016
germ cell development GO:0007281 185 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
regulation of mapk cascade GO:0043408 248 0.015
spermatid differentiation GO:0048515 115 0.015
regulation of cell projection organization GO:0031344 206 0.015
fat cell differentiation GO:0045444 160 0.015
regulation of hormone levels GO:0010817 211 0.015
positive regulation of cell development GO:0010720 237 0.015
maintenance of location GO:0051235 89 0.015
nucleotide catabolic process GO:0009166 217 0.015
organophosphate catabolic process GO:0046434 232 0.015
muscle tissue development GO:0060537 308 0.015
small molecule biosynthetic process GO:0044283 132 0.015
cellular chemical homeostasis GO:0055082 215 0.015
cellular protein complex assembly GO:0043623 116 0.015
intracellular protein transport GO:0006886 204 0.015
leukocyte differentiation GO:0002521 342 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
skeletal system development GO:0001501 356 0.015
mapk cascade GO:0000165 281 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
response to radiation GO:0009314 165 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
positive regulation of cell death GO:0010942 224 0.014
cellular protein catabolic process GO:0044257 155 0.014
regulation of kinase activity GO:0043549 249 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
rho protein signal transduction GO:0007266 32 0.014
cell adhesion GO:0007155 329 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
myeloid cell differentiation GO:0030099 233 0.014
cell type specific apoptotic process GO:0097285 268 0.014
regulation of hydrolase activity GO:0051336 246 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
regulation of cell motility GO:2000145 236 0.014
skeletal system morphogenesis GO:0048705 203 0.014
multicellular organismal signaling GO:0035637 91 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
action potential GO:0001508 78 0.014
regulation of intracellular transport GO:0032386 159 0.014
regionalization GO:0003002 337 0.014
forebrain development GO:0030900 302 0.014
respiratory system development GO:0060541 190 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
mitotic cell cycle GO:0000278 195 0.014
circulatory system process GO:0003013 197 0.014
response to organic cyclic compound GO:0014070 198 0.014
synaptic transmission GO:0007268 329 0.014
mrna metabolic process GO:0016071 84 0.014
chromatin organization GO:0006325 206 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of ion transport GO:0043269 215 0.013
lipid biosynthetic process GO:0008610 179 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
mitotic cell cycle process GO:1903047 159 0.013
gland development GO:0048732 330 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
renal system development GO:0072001 225 0.013
locomotory behavior GO:0007626 195 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
developmental maturation GO:0021700 193 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
endocytosis GO:0006897 168 0.013
transmission of nerve impulse GO:0019226 76 0.013
synapsis GO:0007129 34 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
blood circulation GO:0008015 195 0.013
wnt signaling pathway GO:0016055 188 0.013
regulation of protein kinase activity GO:0045859 232 0.013
cofactor metabolic process GO:0051186 80 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
endomembrane system organization GO:0010256 147 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
response to light stimulus GO:0009416 135 0.013
regulation of cell cycle process GO:0010564 160 0.012
regulation of protein transport GO:0051223 163 0.012
urogenital system development GO:0001655 261 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
homeostasis of number of cells GO:0048872 210 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
meiotic cell cycle process GO:1903046 77 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
regulation of neuron projection development GO:0010975 169 0.012
sequestering of calcium ion GO:0051208 18 0.012
organelle localization GO:0051640 179 0.012
regulation of body fluid levels GO:0050878 162 0.012
lymphocyte differentiation GO:0030098 242 0.012
rna processing GO:0006396 105 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
regulation of anatomical structure size GO:0090066 178 0.012
cellular response to lipid GO:0071396 145 0.012
protein localization to membrane GO:0072657 108 0.012
response to acid chemical GO:0001101 111 0.012
nuclear transport GO:0051169 139 0.012
ossification GO:0001503 216 0.012
cell maturation GO:0048469 127 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
divalent metal ion transport GO:0070838 172 0.012
negative regulation of cell development GO:0010721 169 0.012
positive regulation of cytokine production GO:0001819 174 0.012
innate immune response GO:0045087 157 0.012
negative regulation of cell cycle GO:0045786 123 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
compound eye development GO:0048749 1 0.011
anion transmembrane transport GO:0098656 71 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
methylation GO:0032259 134 0.011
single fertilization GO:0007338 82 0.011
sensory organ morphogenesis GO:0090596 242 0.011
cellular ion homeostasis GO:0006873 165 0.011
oocyte axis specification GO:0007309 2 0.011
carboxylic acid transport GO:0046942 100 0.011
lymphocyte proliferation GO:0046651 164 0.011
neuronal action potential GO:0019228 54 0.011
actin cytoskeleton organization GO:0030036 220 0.011
rna interference GO:0016246 2 0.011
organic acid transport GO:0015849 101 0.011
lateral inhibition GO:0046331 1 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
dna repair GO:0006281 107 0.011
positive regulation of growth GO:0045927 104 0.011
intracellular mrna localization GO:0008298 4 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
regulation of cell migration GO:0030334 219 0.011
divalent inorganic cation transport GO:0072511 178 0.011
anatomical structure homeostasis GO:0060249 145 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
cell growth GO:0016049 130 0.011
regulation of cellular response to stress GO:0080135 159 0.011
muscle cell differentiation GO:0042692 261 0.011
response to inorganic substance GO:0010035 96 0.011
male sex differentiation GO:0046661 109 0.011
circadian rhythm GO:0007623 114 0.011
oocyte construction GO:0007308 2 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of cell adhesion GO:0030155 154 0.011
stem cell differentiation GO:0048863 268 0.011
t cell activation GO:0042110 289 0.011
wound healing GO:0042060 157 0.011
dna recombination GO:0006310 92 0.011
amide transport GO:0042886 138 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of protein catabolic process GO:0042176 108 0.011
sulfur compound metabolic process GO:0006790 100 0.011
male meiosis i GO:0007141 16 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.010
multicellular organism growth GO:0035264 161 0.010
chemotaxis GO:0006935 247 0.010
cognition GO:0050890 149 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
gonad development GO:0008406 141 0.010
learning or memory GO:0007611 148 0.010
striated muscle tissue development GO:0014706 293 0.010
dephosphorylation GO:0016311 129 0.010
protein targeting GO:0006605 143 0.010
development of primary sexual characteristics GO:0045137 143 0.010
positive regulation of transferase activity GO:0051347 167 0.010
extracellular matrix organization GO:0030198 147 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
protein processing GO:0016485 163 0.010
positive regulation of organelle organization GO:0010638 128 0.010
adult behavior GO:0030534 135 0.010
asymmetric stem cell division GO:0098722 3 0.010
multi multicellular organism process GO:0044706 109 0.010
response to oxidative stress GO:0006979 123 0.010
organic acid biosynthetic process GO:0016053 86 0.010
skeletal muscle organ development GO:0060538 163 0.010
kidney development GO:0001822 213 0.010
chromatin modification GO:0016568 187 0.010
alcohol metabolic process GO:0006066 116 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
response to lipopolysaccharide GO:0032496 128 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
leukocyte proliferation GO:0070661 172 0.010
regulation of ossification GO:0030278 112 0.010
protein localization to nucleus GO:0034504 121 0.010
steroid metabolic process GO:0008202 119 0.010

Spaca1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.016
immune system disease DOID:2914 0 0.015
eye disease DOID:5614 0 0.015
musculoskeletal system disease DOID:17 0 0.015
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.013
retinal disease DOID:5679 0 0.011
hematopoietic system disease DOID:74 0 0.011
retinal degeneration DOID:8466 0 0.011