Mus musculus

0 known processes

Ly6a

lymphocyte antigen 6 complex, locus A

(Aliases: TAP,Ly-6A.2,Ly-6E.1,Sca-1,Sca1,Ly-6A/E)

Ly6a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to interferon beta GO:0035458 21 0.373
immune effector process GO:0002252 321 0.361
negative regulation of viral genome replication GO:0045071 10 0.307
heterocycle catabolic process GO:0046700 280 0.299
cellular response to cytokine stimulus GO:0071345 189 0.252
response to interferon beta GO:0035456 22 0.220
defense response to other organism GO:0098542 197 0.181
negative regulation of viral process GO:0048525 23 0.143
cellular response to interferon alpha GO:0035457 4 0.126
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.114
apoptotic signaling pathway GO:0097190 306 0.108
organic cyclic compound catabolic process GO:1901361 295 0.105
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.097
aromatic compound catabolic process GO:0019439 286 0.090
negative regulation of molecular function GO:0044092 258 0.089
purine ribonucleotide catabolic process GO:0009154 208 0.088
nucleoside triphosphate catabolic process GO:0009143 205 0.086
protein maturation GO:0051604 176 0.084
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.080
inflammatory response GO:0006954 244 0.079
nucleotide metabolic process GO:0009117 332 0.078
purine containing compound metabolic process GO:0072521 311 0.077
cellular nitrogen compound catabolic process GO:0044270 280 0.076
negative regulation of protein maturation GO:1903318 79 0.076
lymphocyte differentiation GO:0030098 242 0.074
regulation of multi organism process GO:0043900 111 0.072
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.072
negative regulation of hydrolase activity GO:0051346 71 0.070
cellular amine metabolic process GO:0044106 44 0.067
cation homeostasis GO:0055080 212 0.064
muscle tissue development GO:0060537 308 0.063
purine containing compound catabolic process GO:0072523 213 0.062
negative regulation of cellular protein metabolic process GO:0032269 247 0.062
divalent metal ion transport GO:0070838 172 0.059
calcium ion homeostasis GO:0055074 127 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.057
striated muscle tissue development GO:0014706 293 0.056
protein processing GO:0016485 163 0.055
regulation of cytokine production GO:0001817 266 0.055
negative regulation of peptidase activity GO:0010466 46 0.055
interspecies interaction between organisms GO:0044419 83 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.053
response to organic cyclic compound GO:0014070 198 0.052
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.052
negative regulation of protein metabolic process GO:0051248 282 0.050
glycosyl compound metabolic process GO:1901657 246 0.050
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.050
nucleoside triphosphate metabolic process GO:0009141 230 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
regulation of protein processing GO:0070613 96 0.048
glycoprotein metabolic process GO:0009100 116 0.047
nucleoside phosphate catabolic process GO:1901292 222 0.047
regulation of protein localization GO:0032880 231 0.047
purine ribonucleoside metabolic process GO:0046128 241 0.046
viral gene expression GO:0019080 3 0.045
nucleotide catabolic process GO:0009166 217 0.045
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.045
negative regulation of cell proliferation GO:0008285 296 0.045
guanosine containing compound metabolic process GO:1901068 144 0.045
viral genome replication GO:0019079 17 0.044
ossification GO:0001503 216 0.043
cell type specific apoptotic process GO:0097285 268 0.043
angiogenesis GO:0001525 201 0.043
entry into host cell GO:0030260 15 0.042
purine ribonucleoside catabolic process GO:0046130 205 0.042
regulation of binding GO:0051098 111 0.042
cellular ketone metabolic process GO:0042180 84 0.042
ribonucleoside catabolic process GO:0042454 206 0.041
negative regulation of protein processing GO:0010955 79 0.040
endocytosis GO:0006897 168 0.040
morphogenesis of a branching structure GO:0001763 203 0.040
negative regulation of proteolysis GO:0045861 74 0.039
calcium ion transport GO:0006816 159 0.038
negative regulation of endopeptidase activity GO:0010951 44 0.038
metal ion homeostasis GO:0055065 189 0.037
innate immune response GO:0045087 157 0.037
glycoprotein biosynthetic process GO:0009101 89 0.037
t helper 2 cell cytokine production GO:0035745 4 0.037
positive regulation of osteoblast differentiation GO:0045669 34 0.037
regulation of establishment of protein localization GO:0070201 181 0.036
purine nucleoside catabolic process GO:0006152 205 0.036
regulation of defense response GO:0031347 233 0.036
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
regionalization GO:0003002 337 0.034
ribonucleoside triphosphate catabolic process GO:0009203 199 0.034
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.034
cytokine production GO:0001816 319 0.034
nitrogen compound transport GO:0071705 271 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
macromolecule glycosylation GO:0043413 55 0.033
myeloid leukocyte differentiation GO:0002573 119 0.033
organophosphate catabolic process GO:0046434 232 0.033
nucleoside catabolic process GO:0009164 206 0.033
cell adhesion GO:0007155 329 0.032
eosinophil migration GO:0072677 3 0.032
leukocyte differentiation GO:0002521 342 0.031
organonitrogen compound catabolic process GO:1901565 264 0.031
regulation of hydrolase activity GO:0051336 246 0.031
negative regulation of multi organism process GO:0043901 68 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
actin cytoskeleton organization GO:0030036 220 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
muscle cell development GO:0055001 133 0.029
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of protein maturation GO:1903317 96 0.028
response to interferon alpha GO:0035455 7 0.028
regulation of proteolysis GO:0030162 164 0.027
positive regulation of ossification GO:0045778 47 0.027
cytokine mediated signaling pathway GO:0019221 115 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of protein transport GO:0051223 163 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
regulation of secretion GO:0051046 274 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
viral life cycle GO:0019058 36 0.026
regulation of viral genome replication GO:0045069 13 0.026
defense response to bacterium GO:0042742 119 0.025
mapk cascade GO:0000165 281 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
interleukin 12 secretion GO:0072610 3 0.025
cellular homeostasis GO:0019725 240 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
cation transport GO:0006812 399 0.025
intracellular protein transport GO:0006886 204 0.025
defense response to virus GO:0051607 68 0.025
regulation of vasculature development GO:1901342 88 0.025
regulation of peptide secretion GO:0002791 77 0.025
cellular metal ion homeostasis GO:0006875 151 0.025
divalent inorganic cation homeostasis GO:0072507 138 0.024
nucleoside metabolic process GO:0009116 246 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
regulation of membrane potential GO:0042391 192 0.024
regulation of homeostatic process GO:0032844 182 0.024
t cell activation GO:0042110 289 0.024
regulation of cell motility GO:2000145 236 0.024
protein secretion GO:0009306 111 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
dna metabolic process GO:0006259 303 0.024
b cell activation GO:0042113 161 0.024
divalent inorganic cation transport GO:0072511 178 0.024
regulation of eosinophil migration GO:2000416 2 0.023
carbohydrate metabolic process GO:0005975 230 0.023
t cell differentiation GO:0030217 174 0.023
regulation of hormone levels GO:0010817 211 0.023
interaction with host GO:0051701 22 0.023
protein localization to organelle GO:0033365 185 0.023
macromolecule catabolic process GO:0009057 281 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.022
protein oligomerization GO:0051259 67 0.022
leukocyte migration GO:0050900 124 0.022
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.022
positive regulation of eosinophil migration GO:2000418 2 0.022
gtp metabolic process GO:0046039 144 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
regulation of ossification GO:0030278 112 0.021
anion transport GO:0006820 177 0.021
positive regulation of secretion GO:0051047 130 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
thymocyte migration GO:0072679 2 0.021
endomembrane system organization GO:0010256 147 0.021
response to radiation GO:0009314 165 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
adaptive immune response GO:0002250 155 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
positive regulation of interferon alpha production GO:0032727 4 0.020
regulation of epithelial cell proliferation GO:0050678 141 0.020
blood vessel morphogenesis GO:0048514 285 0.020
iron ion homeostasis GO:0055072 36 0.020
regulation of t cell activation GO:0050863 170 0.020
glycosylation GO:0070085 62 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
negative regulation of viral transcription GO:0032897 3 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
response to growth factor GO:0070848 198 0.019
myeloid cell homeostasis GO:0002262 114 0.019
regulation of peptidase activity GO:0052547 96 0.019
morphogenesis of a branching epithelium GO:0061138 193 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
movement in host environment GO:0052126 15 0.019
regulation of immunological synapse formation GO:2000520 2 0.019
extracellular matrix organization GO:0030198 147 0.019
production of molecular mediator of immune response GO:0002440 103 0.019
cell activation involved in immune response GO:0002263 126 0.019
regulation of production of molecular mediator of immune response GO:0002700 65 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
protein import GO:0017038 101 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
positive regulation of angiogenesis GO:0045766 46 0.018
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.018
multi multicellular organism process GO:0044706 109 0.018
chemotaxis GO:0006935 247 0.018
cellular response to type i interferon GO:0071357 10 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.018
circulatory system process GO:0003013 197 0.018
leukocyte activation involved in immune response GO:0002366 126 0.018
regulation of autophagy GO:0010506 30 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
germ cell development GO:0007281 185 0.017
signal transduction by p53 class mediator GO:0072331 51 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
cytoplasmic transport GO:0016482 234 0.017
cellular ion homeostasis GO:0006873 165 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
sequestering of metal ion GO:0051238 19 0.017
peptidyl amino acid modification GO:0018193 336 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
response to nutrient levels GO:0031667 109 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
regulation of angiogenesis GO:0045765 81 0.017
epithelial cell proliferation GO:0050673 174 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
t helper 1 cell cytokine production GO:0035744 1 0.017
engulfment of apoptotic cell GO:0043652 3 0.016
negative regulation of binding GO:0051100 39 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
regulation of cell activation GO:0050865 289 0.016
viral transcription GO:0019083 3 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
regulation of osteoblast differentiation GO:0045667 67 0.016
alpha beta t cell activation GO:0046631 91 0.016
regulation of secretion by cell GO:1903530 249 0.016
regulation of cytokine secretion GO:0050707 61 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
somitogenesis GO:0001756 69 0.016
epinephrine transport GO:0048241 1 0.016
cellular chemical homeostasis GO:0055082 215 0.016
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.016
regulation of viral transcription GO:0046782 3 0.015
regulation of viral entry into host cell GO:0046596 12 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
skeletal muscle organ development GO:0060538 163 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
regulation of cell adhesion GO:0030155 154 0.015
response to acid chemical GO:0001101 111 0.015
viral process GO:0016032 41 0.015
homeostasis of number of cells GO:0048872 210 0.015
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.015
amine metabolic process GO:0009308 45 0.015
myeloid cell differentiation GO:0030099 233 0.015
amide transport GO:0042886 138 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
epinephrine secretion GO:0048242 1 0.015
rho protein signal transduction GO:0007266 32 0.015
cell cell recognition GO:0009988 44 0.014
cellular lipid metabolic process GO:0044255 323 0.014
regulation of neutrophil apoptotic process GO:0033029 1 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
muscle cell differentiation GO:0042692 261 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
developmental maturation GO:0021700 193 0.014
positive regulation of binding GO:0051099 49 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
maintenance of location GO:0051235 89 0.014
peptide transport GO:0015833 133 0.014
b cell mediated immunity GO:0019724 71 0.014
autophagy GO:0006914 45 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
regulation of actin filament based process GO:0032970 99 0.014
transmembrane transport GO:0055085 412 0.014
fat cell differentiation GO:0045444 160 0.014
epithelial cell development GO:0002064 159 0.014
response to amino acid GO:0043200 37 0.013
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.013
positive regulation of thymocyte migration GO:2000412 2 0.013
nucleoside phosphate biosynthetic process GO:1901293 79 0.013
negative regulation of protein transport GO:0051224 46 0.013
somite development GO:0061053 81 0.013
gtp catabolic process GO:0006184 143 0.013
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.013
regulation of t helper 2 cell cytokine production GO:2000551 3 0.013
natural killer cell chemotaxis GO:0035747 1 0.013
cardiac muscle tissue development GO:0048738 130 0.013
cardiac ventricle development GO:0003231 83 0.013
regulation of body fluid levels GO:0050878 162 0.013
positive regulation of behavior GO:0048520 40 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of response to wounding GO:1903034 189 0.013
multicellular organism growth GO:0035264 161 0.013
midgut development GO:0007494 4 0.013
immunoglobulin production GO:0002377 73 0.013
regulation of cell cycle GO:0051726 281 0.013
regulation of t helper 1 cell cytokine production GO:2000554 1 0.013
organelle assembly GO:0070925 177 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
endothelial cell development GO:0001885 20 0.012
immunoglobulin mediated immune response GO:0016064 69 0.012
plasma cell differentiation GO:0002317 3 0.012
carbohydrate homeostasis GO:0033500 128 0.012
cytokine secretion GO:0050663 72 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
transition metal ion homeostasis GO:0055076 54 0.012
sequestering of calcium ion GO:0051208 18 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
positive regulation of lymphocyte differentiation GO:0045621 61 0.012
methylation GO:0032259 134 0.012
positive regulation of cell death GO:0010942 224 0.012
regulation of adaptive immune response GO:0002819 90 0.012
hormone secretion GO:0046879 128 0.012
negative regulation of macrophage apoptotic process GO:2000110 3 0.012
extracellular structure organization GO:0043062 148 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
macromolecule methylation GO:0043414 120 0.012
myotube differentiation GO:0014902 105 0.012
pyrimidine containing compound catabolic process GO:0072529 3 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
regulation of organelle organization GO:0033043 289 0.012
negative regulation of growth GO:0045926 99 0.012
negative regulation of cytokine production GO:0001818 84 0.012
organic acid biosynthetic process GO:0016053 86 0.012
spermatogenesis GO:0007283 284 0.012
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.012
gonad development GO:0008406 141 0.012
female sex differentiation GO:0046660 84 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
positive regulation of muscle cell differentiation GO:0051149 39 0.012
striated muscle cell development GO:0055002 125 0.012
regulation of metal ion transport GO:0010959 106 0.011
positive regulation of vesicle fusion GO:0031340 2 0.011
nuclear transport GO:0051169 139 0.011
response to steroid hormone GO:0048545 56 0.011
cellular response to thyroid hormone stimulus GO:0097067 1 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
small molecule biosynthetic process GO:0044283 132 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of inflammatory response GO:0050727 147 0.011
negative regulation of immunological synapse formation GO:2000521 1 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
segmentation GO:0035282 93 0.011
peptide secretion GO:0002790 114 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
protein targeting GO:0006605 143 0.011
cellular response to peptide GO:1901653 92 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
multicellular organismal signaling GO:0035637 91 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
response to organonitrogen compound GO:0010243 246 0.011
regulation of muscle tissue development GO:1901861 97 0.011
immunoglobulin production in mucosal tissue GO:0002426 3 0.011
urogenital system development GO:0001655 261 0.011
positive regulation of t cell activation GO:0050870 101 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.011
compound eye development GO:0048749 1 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
protein glycosylation GO:0006486 55 0.011
regulation of mapk cascade GO:0043408 248 0.011
response to stilbenoid GO:0035634 22 0.011
regulation of cell cycle process GO:0010564 160 0.011
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
positive regulation of b cell chemotaxis GO:2000538 2 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
male gamete generation GO:0048232 285 0.010
leukocyte apoptotic process GO:0071887 71 0.010
lipid biosynthetic process GO:0008610 179 0.010
mature dendritic cell differentiation GO:0097029 3 0.010
protein acylation GO:0043543 64 0.010
skin development GO:0043588 220 0.010
ion transmembrane transport GO:0034220 361 0.010
carboxylic acid transport GO:0046942 100 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
sensory perception GO:0007600 245 0.010
regulation of leukocyte apoptotic process GO:2000106 56 0.010
development of primary female sexual characteristics GO:0046545 73 0.010
mitotic cell cycle process GO:1903047 159 0.010
regulation of alpha beta t cell activation GO:0046634 53 0.010
regulation of cell migration GO:0030334 219 0.010
response to ionizing radiation GO:0010212 42 0.010
gland development GO:0048732 330 0.010
response to light stimulus GO:0009416 135 0.010
purine nucleotide biosynthetic process GO:0006164 65 0.010
ear development GO:0043583 200 0.010
regulation of neuron death GO:1901214 134 0.010
positive regulation of immune effector process GO:0002699 107 0.010

Ly6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.038
acquired metabolic disease DOID:0060158 0 0.019
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011