Mus musculus

368 known processes

Sfrp1

secreted frizzled-related protein 1

(Aliases: 2210415K03Rik,AW742929,sFRP-1,AW107218,AW011917)

Sfrp1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
non canonical wnt signaling pathway GO:0035567 33 0.983
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.979
axis elongation involved in somitogenesis GO:0090245 4 0.950
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.939
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.910
regulation of dermatome development GO:0061183 1 0.881
Mouse
hematopoietic stem cell proliferation GO:0071425 13 0.861
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.766
negative regulation of bmp signaling pathway GO:0030514 35 0.741
regulation of establishment of planar polarity GO:0090175 28 0.740
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.731
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.727
regulation of peptidyl serine phosphorylation GO:0033135 39 0.702
Mouse
development of primary female sexual characteristics GO:0046545 73 0.674
negative regulation of jun kinase activity GO:0043508 9 0.664
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.663
Mouse
negative regulation of hepatocyte differentiation GO:0070367 1 0.651
planar cell polarity pathway involved in axis elongation GO:0003402 4 0.638
negative regulation of hydrolase activity GO:0051346 71 0.637
Mouse
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.635
cellular amino acid metabolic process GO:0006520 103 0.622
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.608
Human Mouse
ureteric bud development GO:0001657 94 0.607
cellular response to x ray GO:0071481 2 0.593
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.590
regulation of endopeptidase activity GO:0052548 89 0.585
Mouse
positive regulation of programmed cell death GO:0043068 218 0.583
blood vessel morphogenesis GO:0048514 285 0.582
Mouse
negative regulation of cell growth GO:0030308 44 0.571
Human
regulation of cell migration GO:0030334 219 0.569
Human Mouse
wnt signaling pathway GO:0016055 188 0.562
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.553
female gonad development GO:0008585 71 0.552
morphogenesis of a polarized epithelium GO:0001738 37 0.548
negative regulation of protein maturation GO:1903318 79 0.547
Mouse
neural tube development GO:0021915 160 0.547
positive regulation of apoptotic signaling pathway GO:2001235 95 0.529
positive regulation of apoptotic process GO:0043065 217 0.516
jnk cascade GO:0007254 72 0.503
cell adhesion GO:0007155 329 0.499
extracellular matrix organization GO:0030198 147 0.497
Mouse
negative regulation of protein processing GO:0010955 79 0.491
Mouse
negative regulation of osteoblast proliferation GO:0033689 4 0.487
establishment of planar polarity GO:0001736 28 0.480
cellular amine metabolic process GO:0044106 44 0.478
cellular response to organic cyclic compound GO:0071407 87 0.476
urogenital system development GO:0001655 261 0.470
embryonic appendage morphogenesis GO:0035113 126 0.461
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.459
regulation of jnk cascade GO:0046328 62 0.440
regulation of cellular amine metabolic process GO:0033238 20 0.438
bmp signaling pathway GO:0030509 93 0.433
negative regulation of gastrulation GO:2000542 3 0.429
Mouse
positive regulation of peptidase activity GO:0010952 49 0.429
Mouse
amine metabolic process GO:0009308 45 0.423
regulation of cell motility GO:2000145 236 0.414
Human Mouse
regulation of mapk cascade GO:0043408 248 0.408
catenin import into nucleus GO:0035411 6 0.400
Mouse
positive regulation of cell death GO:0010942 224 0.399
response to x ray GO:0010165 11 0.398
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.397
branching morphogenesis of an epithelial tube GO:0048754 159 0.390
Mouse
positive regulation of catenin import into nucleus GO:0035413 2 0.380
Mouse
regulation of non canonical wnt signaling pathway GO:2000050 12 0.377
female sex differentiation GO:0046660 84 0.374
negative regulation of cell migration GO:0030336 59 0.374
Human Mouse
convergent extension involved in axis elongation GO:0060028 7 0.373
regulation of apoptotic signaling pathway GO:2001233 197 0.373
negative regulation of wnt signaling pathway GO:0030178 73 0.373
sclerotome development GO:0061056 4 0.372
Mouse
regulation of peptidase activity GO:0052547 96 0.368
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.367
positive regulation of cellular amine metabolic process GO:0033240 5 0.365
cell division GO:0051301 120 0.360
Mouse
maintenance of cell number GO:0098727 3 0.354
regulation of protein maturation GO:1903317 96 0.353
Mouse
negative regulation of immune system process GO:0002683 209 0.351
b cell activation GO:0042113 161 0.348
stress activated mapk cascade GO:0051403 80 0.348
embryonic digit morphogenesis GO:0042733 56 0.346
Mouse
limb morphogenesis GO:0035108 149 0.343
Mouse
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.337
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.326
Human
negative regulation of molecular function GO:0044092 258 0.326
neural crest cell fate commitment GO:0014034 1 0.326
regulation of receptor activity GO:0010469 41 0.324
Mouse
regulation of intracellular protein transport GO:0033157 82 0.323
Mouse
negative regulation of endopeptidase activity GO:0010951 44 0.322
Mouse
prostate gland development GO:0030850 48 0.321
regulation of stem cell division GO:2000035 4 0.315
Mouse
prostate glandular acinus development GO:0060525 12 0.315
epithelial tube morphogenesis GO:0060562 303 0.311
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.310
small gtpase mediated signal transduction GO:0007264 97 0.308
regulation of hydrolase activity GO:0051336 246 0.307
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.306
Human Mouse
protein maturation GO:0051604 176 0.306
Mouse
progesterone secretion GO:0042701 1 0.305
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.303
Human Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.301
Human Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.298
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.298
positive regulation of wnt signaling pathway GO:0030177 45 0.294
Human Mouse
apoptotic signaling pathway GO:0097190 306 0.293
negative regulation of cellular amine metabolic process GO:0033239 1 0.292
lymphocyte differentiation GO:0030098 242 0.288
osteoclast differentiation GO:0030316 62 0.284
negative regulation of apoptotic signaling pathway GO:2001234 104 0.283
Mouse
cerebellum vasculature development GO:0061300 1 0.282
chondrocyte development GO:0002063 24 0.280
Mouse
prostate gland morphogenesis GO:0060512 32 0.278
single organism nuclear import GO:1902593 95 0.275
Mouse
negative regulation of catenin import into nucleus GO:0035414 2 0.271
regulation of stress activated mapk cascade GO:0032872 69 0.270
regulation of reproductive process GO:2000241 66 0.267
positive regulation of proteolysis GO:0045862 85 0.267
Mouse
regulation of angiogenesis GO:0045765 81 0.265
Mouse
regulation of proteolysis GO:0030162 164 0.262
Mouse
establishment of protein localization to organelle GO:0072594 118 0.262
Mouse
regulation of protein import into nucleus GO:0042306 52 0.261
Mouse
nucleocytoplasmic transport GO:0006913 139 0.258
Mouse
myeloid cell differentiation GO:0030099 233 0.258
regulation of cell growth GO:0001558 91 0.255
Human Mouse
mesonephric duct morphogenesis GO:0072180 4 0.254
angiogenesis GO:0001525 201 0.253
Mouse
stem cell proliferation GO:0072089 117 0.252
Mouse
mesonephric tubule development GO:0072164 94 0.252
stress activated protein kinase signaling cascade GO:0031098 81 0.251
myeloid leukocyte differentiation GO:0002573 119 0.251
regulation of protein kinase activity GO:0045859 232 0.250
chondrocyte differentiation GO:0002062 72 0.247
Mouse
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.246
bone development GO:0060348 120 0.246
Mouse
protein processing GO:0016485 163 0.244
Mouse
regulation of protein transport GO:0051223 163 0.243
Mouse
cellular ketone metabolic process GO:0042180 84 0.243
intracellular protein transport GO:0006886 204 0.241
Mouse
regulation of protein targeting GO:1903533 61 0.241
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.241
regulation of organ morphogenesis GO:2000027 144 0.240
negative regulation of phosphate metabolic process GO:0045936 184 0.238
convergent extension GO:0060026 14 0.233
morphogenesis of embryonic epithelium GO:0016331 159 0.232
protein localization to nucleus GO:0034504 121 0.231
Mouse
negative regulation of myeloid cell differentiation GO:0045638 38 0.229
positive regulation of intracellular transport GO:0032388 70 0.227
Mouse
cellular response to hormone stimulus GO:0032870 150 0.227
nuclear transport GO:0051169 139 0.227
Mouse
muscular septum morphogenesis GO:0003150 4 0.225
regulation of canonical wnt signaling pathway GO:0060828 82 0.220
regulation of protein localization to nucleus GO:1900180 60 0.219
Mouse
negative regulation of leukocyte differentiation GO:1902106 51 0.219
canonical wnt signaling pathway GO:0060070 130 0.217
kidney development GO:0001822 213 0.216
negative regulation of growth GO:0045926 99 0.215
post anal tail morphogenesis GO:0036342 23 0.213
Mouse
regulation of map kinase activity GO:0043405 120 0.212
appendage development GO:0048736 166 0.206
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.206
negative regulation of lymphocyte differentiation GO:0045620 32 0.204
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.202
renal system development GO:0072001 225 0.201
peptidyl serine modification GO:0018209 83 0.200
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.199
cerebellum vasculature morphogenesis GO:0061301 1 0.199
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.197
regulation of chorionic trophoblast cell proliferation GO:1901382 1 0.197
negative regulation of cellular component organization GO:0051129 194 0.196
Human
regulation of kinase activity GO:0043549 249 0.192
regulation of protein processing GO:0070613 96 0.192
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.192
neural crest formation GO:0014029 2 0.191
striated muscle tissue development GO:0014706 293 0.189
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.188
regulation of cell activation GO:0050865 289 0.187
prostate glandular acinus morphogenesis GO:0060526 7 0.184
single organismal cell cell adhesion GO:0016337 131 0.183
mesonephric epithelium development GO:0072163 94 0.183
trabecula morphogenesis GO:0061383 40 0.181
establishment of tissue polarity GO:0007164 28 0.180
cytoplasmic transport GO:0016482 234 0.179
Mouse
respiratory tube development GO:0030323 167 0.178
regulation of b cell activation GO:0050864 81 0.178
peptidyl serine phosphorylation GO:0018105 74 0.178
Mouse
mapk cascade GO:0000165 281 0.175
negative regulation of epithelial cell proliferation GO:0050680 64 0.173
Human
protein import GO:0017038 101 0.169
Mouse
stem cell differentiation GO:0048863 268 0.168
negative regulation of kinase activity GO:0033673 81 0.167
mesenchyme development GO:0060485 152 0.165
negative regulation of cellular protein metabolic process GO:0032269 247 0.165
regulation of epithelial to mesenchymal transition GO:0010717 22 0.165
Human
bone trabecula morphogenesis GO:0061430 12 0.165
regulation of muscle cell apoptotic process GO:0010660 17 0.164
Mouse
regulation of protein localization GO:0032880 231 0.163
Mouse
male gonad development GO:0008584 88 0.163
negative regulation of cell motility GO:2000146 61 0.161
Human Mouse
extracellular structure organization GO:0043062 148 0.159
Mouse
retinal blood vessel morphogenesis GO:0061304 3 0.159
mesenchymal cell differentiation GO:0048762 107 0.159
response to radiation GO:0009314 165 0.159
single organism cell adhesion GO:0098602 156 0.158
epithelial cell proliferation GO:0050673 174 0.158
Human
cellular response to radiation GO:0071478 28 0.156
negative regulation of execution phase of apoptosis GO:1900118 4 0.156
regulation of osteoclast differentiation GO:0045670 36 0.156
regulation of establishment of protein localization GO:0070201 181 0.155
Mouse
skeletal system development GO:0001501 356 0.154
positive regulation of protein import into nucleus GO:0042307 26 0.154
Mouse
negative regulation of phosphorylation GO:0042326 166 0.154
negative regulation of protein phosphorylation GO:0001933 126 0.153
actin cytoskeleton organization GO:0030036 220 0.153
negative regulation of lymphocyte activation GO:0051250 91 0.152
nuclear import GO:0051170 95 0.151
Mouse
response to steroid hormone GO:0048545 56 0.151
positive regulation of non canonical wnt signaling pathway GO:2000052 6 0.147
Human
skeletal system morphogenesis GO:0048705 203 0.147
regulation of intracellular transport GO:0032386 159 0.146
Mouse
embryonic limb morphogenesis GO:0030326 126 0.145
Mouse
regulation of actin filament based process GO:0032970 99 0.144
cardiac muscle cell apoptotic process GO:0010659 10 0.144
Mouse
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.142
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.142
response to extracellular stimulus GO:0009991 127 0.141
Human Mouse
mesoderm morphogenesis GO:0048332 64 0.140
Mouse
regulation of cellular response to stress GO:0080135 159 0.139
rho protein signal transduction GO:0007266 32 0.136
positive regulation of cytoplasmic transport GO:1903651 40 0.135
Mouse
regulation of body fluid levels GO:0050878 162 0.134
negative regulation of cell proliferation GO:0008285 296 0.134
cerebellum development GO:0021549 77 0.133
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.133
limb development GO:0060173 166 0.133
Mouse
epidermis development GO:0008544 187 0.132
cellular response to steroid hormone stimulus GO:0071383 33 0.131
negative regulation of b cell differentiation GO:0045578 4 0.128
stem cell division GO:0017145 30 0.127
Mouse
mesoderm formation GO:0001707 62 0.126
Mouse
muscle cell apoptotic process GO:0010657 18 0.126
Mouse
primary neural tube formation GO:0014020 95 0.126
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.125
Mouse
kidney epithelium development GO:0072073 121 0.125
macromolecule catabolic process GO:0009057 281 0.124
positive regulation of protein modification process GO:0031401 299 0.122
Mouse
embryonic epithelial tube formation GO:0001838 130 0.122
heart morphogenesis GO:0003007 178 0.122
positive regulation of protein kinase activity GO:0045860 144 0.122
stem cell development GO:0048864 219 0.121
cell growth GO:0016049 130 0.120
Human Mouse
pallium development GO:0021543 120 0.118
lateral line system development GO:0048925 1 0.118
cellular chemical homeostasis GO:0055082 215 0.118
neural tube closure GO:0001843 90 0.113
leukocyte differentiation GO:0002521 342 0.113
regulation of b cell differentiation GO:0045577 23 0.113
positive regulation of endopeptidase activity GO:0010950 43 0.113
Mouse
regulation of ossification GO:0030278 112 0.111
ras protein signal transduction GO:0007265 77 0.110
regulation of neuron differentiation GO:0045664 281 0.110
axon guidance GO:0007411 141 0.110
regulation of cell cycle GO:0051726 281 0.110
Human
negative regulation of osteoclast differentiation GO:0045671 12 0.109
ameboidal type cell migration GO:0001667 128 0.109
positive regulation of interleukin 8 secretion GO:2000484 1 0.104
regulation of embryonic development GO:0045995 71 0.104
negative regulation of protein modification process GO:0031400 163 0.104
neural tube formation GO:0001841 108 0.103
positive regulation of protein localization to nucleus GO:1900182 30 0.103
Mouse
purine nucleotide metabolic process GO:0006163 302 0.102
positive regulation of map kinase activity GO:0043406 84 0.102
ossification GO:0001503 216 0.101
regulation of wnt signaling pathway GO:0030111 123 0.100
regulation of vasculature development GO:1901342 88 0.100
Mouse
bone remodeling GO:0046849 53 0.100
Human
embryonic nail plate morphogenesis GO:0035880 3 0.099
negative regulation of intracellular signal transduction GO:1902532 167 0.099
positive regulation of ossification GO:0045778 47 0.098
Mouse
appendage morphogenesis GO:0035107 149 0.098
Mouse
tube formation GO:0035148 140 0.097
cellular response to ionizing radiation GO:0071479 11 0.097
hair cycle phase GO:0044851 16 0.096
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.096
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.096
Human Mouse
tissue remodeling GO:0048771 102 0.095
Human
gland development GO:0048732 330 0.095
regulation of organelle organization GO:0033043 289 0.095
hair follicle development GO:0001942 85 0.095
negative regulation of protein metabolic process GO:0051248 282 0.094
peptidyl amino acid modification GO:0018193 336 0.094
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.092
steroid metabolic process GO:0008202 119 0.091
negative regulation of osteoblast differentiation GO:0045668 30 0.091
negative regulation of muscle cell apoptotic process GO:0010656 9 0.091
Mouse
gtp metabolic process GO:0046039 144 0.090
chemotaxis GO:0006935 247 0.090
positive regulation of mapk cascade GO:0043410 170 0.090
regulation of jun kinase activity GO:0043506 40 0.090
inflammatory response GO:0006954 244 0.090
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.087
negative regulation of cell development GO:0010721 169 0.086
Human
cell type specific apoptotic process GO:0097285 268 0.086
Human Mouse
response to ionizing radiation GO:0010212 42 0.086
regulation of transferase activity GO:0051338 263 0.085
nucleoside phosphate metabolic process GO:0006753 338 0.085
peptidyl tyrosine modification GO:0018212 145 0.085
Human Mouse
negative regulation of b cell activation GO:0050869 27 0.084
regulation of tube size GO:0035150 57 0.084
epithelial tube formation GO:0072175 130 0.084
regulation of osteoblast differentiation GO:0045667 67 0.083
embryonic skeletal system development GO:0048706 120 0.083
mesenchymal cell development GO:0014031 93 0.083
biomineral tissue development GO:0031214 64 0.083
purine ribonucleoside catabolic process GO:0046130 205 0.083
bone morphogenesis GO:0060349 78 0.082
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.082
Human
response to vitamin d GO:0033280 3 0.082
Human
regulation of ras gtpase activity GO:0032318 88 0.082
regulation of anatomical structure size GO:0090066 178 0.082
regulation of cytoplasmic transport GO:1903649 112 0.082
Mouse
negative regulation of mitotic cell cycle embryonic GO:0045976 2 0.081
negative regulation of mesoderm development GO:2000381 8 0.081
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.081
cell fate commitment GO:0045165 210 0.080
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.080
axis elongation GO:0003401 30 0.080
purine ribonucleotide metabolic process GO:0009150 290 0.078
central nervous system neuron development GO:0021954 67 0.078
negative regulation of mapk cascade GO:0043409 65 0.077
response to organic cyclic compound GO:0014070 198 0.077
ribonucleoside triphosphate metabolic process GO:0009199 220 0.077
stem cell maintenance GO:0019827 130 0.077
digestive system development GO:0055123 200 0.076
nucleoside triphosphate metabolic process GO:0009141 230 0.076
organophosphate catabolic process GO:0046434 232 0.076
prostate gland epithelium morphogenesis GO:0060740 31 0.076
cardiac chamber development GO:0003205 108 0.076
regulation of cardiac muscle cell apoptotic process GO:0010665 9 0.075
Mouse
response to nutrient levels GO:0031667 109 0.075
Human
organic hydroxy compound metabolic process GO:1901615 203 0.074
chorion development GO:0060717 7 0.074
guanosine containing compound metabolic process GO:1901068 144 0.074
regulation of actin cytoskeleton organization GO:0032956 84 0.073
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 5 0.073
midgut development GO:0007494 4 0.073
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.073
Human
regulation of neuron projection development GO:0010975 169 0.071
male sex differentiation GO:0046661 109 0.071
negative chemotaxis GO:0050919 14 0.070
negative regulation of proteolysis GO:0045861 74 0.070
Mouse
mitotic cell cycle GO:0000278 195 0.070
regulation of rho gtpase activity GO:0032319 58 0.070
sensory organ morphogenesis GO:0090596 242 0.070
nucleotide catabolic process GO:0009166 217 0.070
cellular response to lipid GO:0071396 145 0.069
cellular response to estrogen stimulus GO:0071391 12 0.069
hair cycle GO:0042633 90 0.068
positive regulation of osteoblast differentiation GO:0045669 34 0.068
Mouse
neural crest cell differentiation GO:0014033 54 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
protein import into nucleus GO:0006606 95 0.068
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.067
Mouse
rhythmic process GO:0048511 174 0.067
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.067
Mouse
actin filament organization GO:0007015 113 0.067
negative regulation of phosphorus metabolic process GO:0010563 184 0.067
wound healing GO:0042060 157 0.067
protein catabolic process GO:0030163 221 0.067
aromatic compound catabolic process GO:0019439 286 0.066
purine nucleoside metabolic process GO:0042278 241 0.066
cell substrate adhesion GO:0031589 130 0.066
striated muscle cell apoptotic process GO:0010658 12 0.066
Mouse
axonogenesis GO:0007409 274 0.066
cytokine production GO:0001816 319 0.066
hepaticobiliary system development GO:0061008 67 0.065
negative regulation of striated muscle cell apoptotic process GO:0010664 8 0.065
Mouse
cell cell junction organization GO:0045216 72 0.065
meiotic cell cycle GO:0051321 122 0.064
regulation of myeloid leukocyte differentiation GO:0002761 58 0.063
positive regulation of neuron differentiation GO:0045666 141 0.063
purine ribonucleoside metabolic process GO:0046128 241 0.063
anatomical structure maturation GO:0071695 49 0.063
blood circulation GO:0008015 195 0.062
positive regulation of growth GO:0045927 104 0.062
Human Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.062
regulation of cellular catabolic process GO:0031329 242 0.062
segmentation GO:0035282 93 0.061
hindbrain development GO:0030902 128 0.061
cellular response to organonitrogen compound GO:0071417 145 0.061
Human
response to acid chemical GO:0001101 111 0.060
Human Rat
regulation of secretion GO:0051046 274 0.060
Human
locomotory behavior GO:0007626 195 0.060
cell proliferation in midbrain GO:0033278 2 0.060
palate development GO:0060021 76 0.060
developmental maturation GO:0021700 193 0.060
positive regulation of cytokine production GO:0001819 174 0.060
regulation of protein catabolic process GO:0042176 108 0.059
neural precursor cell proliferation GO:0061351 121 0.059
connective tissue development GO:0061448 179 0.059
Mouse
epithelial cell development GO:0002064 159 0.058
regulation of epithelial cell proliferation GO:0050678 141 0.058
Human
lipid biosynthetic process GO:0008610 179 0.058
epithelium migration GO:0090132 63 0.058
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.058
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.057
regulation of gtp catabolic process GO:0033124 113 0.057
regulation of cytokine production GO:0001817 266 0.057
metal ion homeostasis GO:0055065 189 0.057
regulation of cell substrate adhesion GO:0010810 73 0.056
regulation of myeloid cell differentiation GO:0045637 96 0.056
morphogenesis of a branching structure GO:0001763 203 0.056
positive regulation of protein transport GO:0051222 93 0.056
Mouse
cell fate specification GO:0001708 72 0.056
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.056
interleukin 8 secretion GO:0072606 3 0.055
ribonucleotide metabolic process GO:0009259 291 0.055
cell chemotaxis GO:0060326 81 0.055
regulation of membrane potential GO:0042391 192 0.055
transmembrane transport GO:0055085 412 0.054
lung development GO:0030324 164 0.053
regulation of smoothened signaling pathway GO:0008589 58 0.053
Human
trachea cartilage morphogenesis GO:0060535 4 0.053
cellular response to external stimulus GO:0071496 88 0.053
Human Mouse
tissue regeneration GO:0042246 22 0.052
outflow tract morphogenesis GO:0003151 53 0.052
compound eye development GO:0048749 1 0.052
response to estrogen GO:0043627 24 0.052
cardiac muscle tissue development GO:0048738 130 0.052
monocarboxylic acid metabolic process GO:0032787 191 0.052
heterocycle catabolic process GO:0046700 280 0.051
positive regulation of jun kinase activity GO:0043507 30 0.051
oxidation reduction process GO:0055114 342 0.051
positive regulation of cell development GO:0010720 237 0.051
cell matrix adhesion GO:0007160 68 0.051
organic acid transport GO:0015849 101 0.051
small molecule biosynthetic process GO:0044283 132 0.051
cerebellum morphogenesis GO:0021587 42 0.050
regionalization GO:0003002 337 0.050
regulation of transforming growth factor beta2 production GO:0032909 2 0.050
regulation of secretion by cell GO:1903530 249 0.050
Human
positive regulation of smoothened signaling pathway GO:0045880 23 0.050
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.050
regulation of execution phase of apoptosis GO:1900117 9 0.049
negative regulation of epithelial to mesenchymal transition GO:0010719 6 0.049
Human
positive regulation of cell adhesion GO:0045785 80 0.049
cardiac chamber morphogenesis GO:0003206 93 0.049
ribonucleoside catabolic process GO:0042454 206 0.049
somatic stem cell maintenance GO:0035019 47 0.048
organic cyclic compound catabolic process GO:1901361 295 0.048
positive regulation of cell projection organization GO:0031346 95 0.047
smooth muscle cell chemotaxis GO:0071670 2 0.047
blood coagulation GO:0007596 76 0.047
renal outer medulla development GO:0072054 2 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.046
nucleoside metabolic process GO:0009116 246 0.046
regulation of mesoderm development GO:2000380 12 0.046
Mouse
regulation of response to wounding GO:1903034 189 0.046
bone trabecula formation GO:0060346 9 0.046
protein targeting GO:0006605 143 0.046
Mouse
positive regulation of nervous system development GO:0051962 221 0.046
cellular ion homeostasis GO:0006873 165 0.046
insulin processing GO:0030070 2 0.046
purine nucleoside catabolic process GO:0006152 205 0.045
positive regulation of cell growth GO:0030307 33 0.045
Human Mouse
cellular macromolecule catabolic process GO:0044265 206 0.045
endothelial cell migration GO:0043542 44 0.045
regulation of stem cell differentiation GO:2000736 50 0.045
Human
gtp catabolic process GO:0006184 143 0.045
action potential GO:0001508 78 0.045
regulation of astrocyte differentiation GO:0048710 20 0.045
cellular lipid metabolic process GO:0044255 323 0.045
cellular protein catabolic process GO:0044257 155 0.045
labyrinthine layer blood vessel development GO:0060716 21 0.044
mesoderm development GO:0007498 100 0.044
Mouse
ribonucleoside metabolic process GO:0009119 245 0.044
cellular response to growth factor stimulus GO:0071363 197 0.044
Human
gonad development GO:0008406 141 0.044
mammary gland morphogenesis GO:0060443 54 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
fat cell differentiation GO:0045444 160 0.043
Human
cellular carbohydrate metabolic process GO:0044262 119 0.043
cellular response to abiotic stimulus GO:0071214 56 0.043
response to peptide GO:1901652 136 0.043
camera type eye development GO:0043010 266 0.043
nitrogen compound transport GO:0071705 271 0.043
Human
cognition GO:0050890 149 0.042
sequestering of calcium ion GO:0051208 18 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
regulation of rho protein signal transduction GO:0035023 71 0.042
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.042
skin development GO:0043588 220 0.041
hormone metabolic process GO:0042445 86 0.041
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.041
t cell differentiation GO:0030217 174 0.041
negative regulation of phospholipase activity GO:0010519 4 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.040
alcohol metabolic process GO:0006066 116 0.040
central nervous system neuron differentiation GO:0021953 162 0.039
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.039
regulation of synaptic plasticity GO:0048167 87 0.039

Sfrp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org