|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.591
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.536
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.528
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.490
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.479
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.407
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.307
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.277
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.274
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.265
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.265
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.262
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.261
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.253
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.248
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.239
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.238
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.236
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.235
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.232
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.230
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.222
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.211
|
Mouse Rat |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.208
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.192
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.187
|
Worm |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.186
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.183
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.182
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.172
|
Worm |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.169
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.164
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.154
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.153
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.153
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.153
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.152
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.151
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.151
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.144
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.142
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.138
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.135
|
Mouse Worm |
|
|
protein processing
|
GO:0016485 |
163 |
0.135
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.134
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.131
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.130
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.127
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.125
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.125
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.123
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.121
|
|
|
|
regulation of angiotensin metabolic process
|
GO:0060177 |
4 |
0.120
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.118
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.117
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
3 |
0.116
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.114
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
32 |
0.112
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.110
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.108
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.106
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.105
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.105
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.104
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.103
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.103
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.103
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.102
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.102
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.099
|
Rat |
|
|
innate immune response
|
GO:0045087 |
157 |
0.098
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.097
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.097
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.096
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.094
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.093
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.091
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.091
|
Mouse Rat |
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.091
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.090
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.089
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.088
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.088
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.088
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.086
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.086
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.085
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.084
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.084
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.084
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.083
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.082
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.082
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.082
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.081
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.081
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.080
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.080
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.079
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.079
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.078
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.077
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.075
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.074
|
Mouse |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.072
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.072
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.071
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.070
|
|
|
|
acetylcholine secretion neurotransmission
|
GO:0014055 |
2 |
0.069
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.068
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.068
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.067
|
Worm |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.067
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.067
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.067
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.066
|
Worm |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.066
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.065
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.064
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.064
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.064
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.063
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.063
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.062
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.062
|
Human Mouse |
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.061
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.061
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.061
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
25 |
0.061
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.061
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.060
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.059
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.059
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.059
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.059
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.059
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.058
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.058
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.058
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.058
|
Worm |
|
|
organic anion transport
|
GO:0015711 |
137 |
0.058
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.057
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.057
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.057
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.056
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.056
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.055
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.055
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.055
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.055
|
Mouse |
|
|
regulation of phospholipid biosynthetic process
|
GO:0071071 |
3 |
0.055
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.054
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.054
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.054
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.054
|
Human |
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.053
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.053
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.052
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.052
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.052
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.052
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.052
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.051
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.051
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.051
|
Mouse |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.051
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.051
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.050
|
Mouse |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.050
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.050
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.049
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.049
|
Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.049
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.049
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
31 |
0.049
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.049
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.048
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.048
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.048
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.048
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.048
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.047
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.047
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.047
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.046
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.046
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.046
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.046
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.045
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.045
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.045
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.045
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.044
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.044
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.044
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.044
|
Mouse |
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.044
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.044
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.043
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.043
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.043
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.043
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.043
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.042
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.042
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.042
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.042
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.042
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.041
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.041
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.041
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.040
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.040
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.040
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.040
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.040
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.040
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.040
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.039
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.039
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.039
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.039
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.038
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.038
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.038
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.038
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.038
|
Rat Worm |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.038
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.037
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.037
|
Rat |
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.037
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.037
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.037
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.037
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.037
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
33 |
0.037
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.036
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.036
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.036
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.035
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.035
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.035
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.035
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.035
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.035
|
Mouse |
|
|
cellular response to prostaglandin d stimulus
|
GO:0071799 |
1 |
0.034
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.034
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.034
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.034
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.034
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.034
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.034
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.034
|
|
|
|
bronchiole development
|
GO:0060435 |
3 |
0.034
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.034
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.034
|
Mouse |
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.034
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.034
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.034
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.033
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.033
|
Mouse |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.033
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.033
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.033
|
Human Mouse Rat Worm |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.033
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.033
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.032
|
Mouse |
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.032
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.032
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.032
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.032
|
Mouse |
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.032
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.032
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.032
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.032
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.032
|
Mouse |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.031
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.031
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.031
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.031
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.031
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.031
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.031
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.031
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.031
|
Human Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.030
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.030
|
|
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.030
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.030
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.030
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.030
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.030
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.030
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.029
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.029
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.029
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.029
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.029
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.029
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.029
|
Mouse |
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.029
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.029
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.028
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.028
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.028
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.028
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.028
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.028
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.028
|
Mouse Rat |
|
|
molting cycle
|
GO:0042303 |
90 |
0.028
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.028
|
Mouse |
|
|
kidney development
|
GO:0001822 |
213 |
0.028
|
|
|
|
norepinephrine secretion
|
GO:0048243 |
2 |
0.028
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.028
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.028
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.028
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.028
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.028
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.028
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.028
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.027
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.027
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.027
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.027
|
Human Mouse Rat |
|
|
neuron migration
|
GO:0001764 |
122 |
0.027
|
Mouse |
|
|
exocytosis
|
GO:0006887 |
121 |
0.027
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.027
|
Mouse |
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.027
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.027
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.027
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.027
|
Mouse |
|
|
fatty acid derivative biosynthetic process
|
GO:1901570 |
15 |
0.026
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.026
|
|
|
|
icosanoid biosynthetic process
|
GO:0046456 |
15 |
0.026
|
|
|
|
cellular response to prostaglandin stimulus
|
GO:0071379 |
2 |
0.026
|
|
|
|
positive regulation of catecholamine secretion
|
GO:0033605 |
2 |
0.026
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.026
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.026
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.026
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.026
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.026
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.026
|
Mouse |
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.026
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.026
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.026
|
Human |
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.026
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.026
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.025
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.025
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.025
|
|
|
|
sphingolipid biosynthetic process
|
GO:0030148 |
26 |
0.025
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.025
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.025
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.025
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.025
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.025
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.025
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.025
|
|
|
|
lateral geniculate nucleus development
|
GO:0021771 |
1 |
0.025
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.025
|
Mouse Worm |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.025
|
Human |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.024
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.024
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.024
|
Rat |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.024
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.024
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.024
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.024
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.024
|
Mouse |
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.024
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.024
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.024
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.024
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.024
|
Mouse |
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.023
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.023
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.023
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.023
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.023
|
Mouse |
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.023
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.023
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.023
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.023
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.023
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.023
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.022
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.022
|
|
|
|
physiological cardiac muscle hypertrophy
|
GO:0003301 |
3 |
0.022
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.022
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.022
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.022
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.022
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.022
|
|
|
|
norepinephrine transport
|
GO:0015874 |
2 |
0.022
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.022
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.022
|
Mouse |
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.022
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.022
|
|
|
|
cellular water homeostasis
|
GO:0009992 |
2 |
0.022
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.022
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.022
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.021
|
|
|
|
endocrine process
|
GO:0050886 |
39 |
0.021
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.021
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.021
|
Mouse |
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.021
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.021
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.021
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.021
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.021
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.021
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.021
|
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
33 |
0.021
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.021
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.021
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.021
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.021
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.020
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.020
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.020
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.020
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.020
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.020
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.020
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.020
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.020
|
Mouse |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.020
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.020
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.020
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.020
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.020
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.020
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.020
|
|
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.020
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.020
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.020
|
|
|
|
ceramide biosynthetic process
|
GO:0046513 |
20 |
0.020
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.020
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.020
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.019
|
Mouse |
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.019
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.019
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.019
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.019
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.019
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.019
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.019
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.019
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.019
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.019
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.019
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.019
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.019
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.019
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.019
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.019
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.018
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.018
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.018
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.018
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.018
|
|
|
|
cellular response to prostaglandin e stimulus
|
GO:0071380 |
1 |
0.018
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.018
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.018
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.018
|
Mouse |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.018
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.018
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.018
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.018
|
Mouse Worm |
|
|
positive regulation of high voltage gated calcium channel activity
|
GO:1901843 |
1 |
0.018
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.018
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.018
|
|
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.018
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.018
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.018
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.018
|
Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.018
|
Mouse |
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.018
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.018
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.018
|
|
|
|
leukotriene production involved in inflammatory response
|
GO:0002540 |
2 |
0.018
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.018
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.018
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.017
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.017
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.017
|
Worm |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.017
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.017
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.017
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.017
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.017
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.017
|
|
