Mus musculus

0 known processes

Grk4

G protein-coupled receptor kinase 4

(Aliases: Gprk2l,GRK,A830025H08Rik,Gprk4)

Grk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.049
cellular ketone metabolic process GO:0042180 84 0.048
cellular amino acid metabolic process GO:0006520 103 0.045
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
cellular amine metabolic process GO:0044106 44 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
dna metabolic process GO:0006259 303 0.034
spermatogenesis GO:0007283 284 0.033
male gamete generation GO:0048232 285 0.033
negative regulation of molecular function GO:0044092 258 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.029
cellular lipid metabolic process GO:0044255 323 0.028
cation transport GO:0006812 399 0.028
ras protein signal transduction GO:0007265 77 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.026
transmembrane transport GO:0055085 412 0.026
cilium assembly GO:0042384 81 0.026
immune effector process GO:0002252 321 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
small gtpase mediated signal transduction GO:0007264 97 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
regulation of organelle organization GO:0033043 289 0.023
male meiosis GO:0007140 37 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
negative regulation of protein metabolic process GO:0051248 282 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
microtubule based movement GO:0007018 84 0.022
membrane organization GO:0061024 245 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
oxidation reduction process GO:0055114 342 0.021
sensory perception GO:0007600 245 0.021
nucleotide metabolic process GO:0009117 332 0.021
fertilization GO:0009566 127 0.021
leukocyte differentiation GO:0002521 342 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.020
positive regulation of protein modification process GO:0031401 299 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
immune response regulating signaling pathway GO:0002764 125 0.020
positive regulation of cell death GO:0010942 224 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
organelle fission GO:0048285 170 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
forebrain development GO:0030900 302 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.019
regulation of cell cycle GO:0051726 281 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
meiotic cell cycle GO:0051321 122 0.019
ion transmembrane transport GO:0034220 361 0.019
inflammatory response GO:0006954 244 0.019
positive regulation of nervous system development GO:0051962 221 0.019
microtubule based process GO:0007017 236 0.019
meiotic nuclear division GO:0007126 115 0.019
reactive nitrogen species metabolic process GO:2001057 0 0.019
transmission of nerve impulse GO:0019226 76 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
protein processing GO:0016485 163 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
positive regulation of cell development GO:0010720 237 0.019
dna repair GO:0006281 107 0.019
divalent inorganic cation transport GO:0072511 178 0.019
intracellular protein transport GO:0006886 204 0.019
mapk cascade GO:0000165 281 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
cytokine production GO:0001816 319 0.019
protein maturation GO:0051604 176 0.018
protein ubiquitination GO:0016567 171 0.018
cellular homeostasis GO:0019725 240 0.018
apoptotic signaling pathway GO:0097190 306 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of neuron differentiation GO:0045664 281 0.018
response to organonitrogen compound GO:0010243 246 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
nuclear division GO:0000280 158 0.018
regulation of transferase activity GO:0051338 263 0.018
regulation of protein transport GO:0051223 163 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
innate immune response GO:0045087 157 0.018
endocytosis GO:0006897 168 0.018
Human Rat
regulation of secretion GO:0051046 274 0.018
cation transmembrane transport GO:0098655 266 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
regulation of cell projection organization GO:0031344 206 0.017
regulation of protein kinase activity GO:0045859 232 0.017
regulation of membrane potential GO:0042391 192 0.017
neuronal action potential GO:0019228 54 0.017
synapsis GO:0007129 34 0.017
cilium morphogenesis GO:0060271 102 0.017
cytoplasmic transport GO:0016482 234 0.017
sensory organ morphogenesis GO:0090596 242 0.017
Mouse
tissue homeostasis GO:0001894 115 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
methylation GO:0032259 134 0.017
meiotic cell cycle process GO:1903046 77 0.016
response to radiation GO:0009314 165 0.016
Mouse
regulation of protein localization GO:0032880 231 0.016
regulation of mapk cascade GO:0043408 248 0.016
leukocyte mediated immunity GO:0002443 174 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
homeostasis of number of cells GO:0048872 210 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
regulation of cell motility GO:2000145 236 0.016
nitrogen compound transport GO:0071705 271 0.016
purine containing compound metabolic process GO:0072521 311 0.016
nucleotide catabolic process GO:0009166 217 0.016
regulation of t cell activation GO:0050863 170 0.016
endomembrane system organization GO:0010256 147 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
regulation of kinase activity GO:0043549 249 0.016
negative regulation of cell development GO:0010721 169 0.016
purine nucleotide metabolic process GO:0006163 302 0.015
negative regulation of immune system process GO:0002683 209 0.015
protein catabolic process GO:0030163 221 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
protein localization to organelle GO:0033365 185 0.015
multicellular organismal signaling GO:0035637 91 0.015
sequestering of metal ion GO:0051238 19 0.015
purine containing compound catabolic process GO:0072523 213 0.015
aromatic compound catabolic process GO:0019439 286 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
chromosome organization involved in meiosis GO:0070192 39 0.015
peptidyl amino acid modification GO:0018193 336 0.015
Mouse
regulation of cytokine production GO:0001817 266 0.015
macromolecule catabolic process GO:0009057 281 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
dna recombination GO:0006310 92 0.015
activation of immune response GO:0002253 138 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
regulation of defense response GO:0031347 233 0.015
t cell activation GO:0042110 289 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
stem cell differentiation GO:0048863 268 0.015
lymphocyte differentiation GO:0030098 242 0.014
positive regulation of transferase activity GO:0051347 167 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
organelle assembly GO:0070925 177 0.014
regulation of cell migration GO:0030334 219 0.014
heterocycle catabolic process GO:0046700 280 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
regulation of ion transport GO:0043269 215 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
regulation of proteolysis GO:0030162 164 0.014
cellular protein catabolic process GO:0044257 155 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
carbohydrate metabolic process GO:0005975 230 0.014
response to growth factor GO:0070848 198 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
cell type specific apoptotic process GO:0097285 268 0.014
cellular chemical homeostasis GO:0055082 215 0.014
regulation of cellular response to stress GO:0080135 159 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
organelle localization GO:0051640 179 0.014
meiosis i GO:0007127 60 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
camera type eye development GO:0043010 266 0.014
Mouse
anatomical structure homeostasis GO:0060249 145 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
maintenance of location GO:0051235 89 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
regulation of protein catabolic process GO:0042176 108 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
rho protein signal transduction GO:0007266 32 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
positive regulation of cell activation GO:0050867 158 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
regulation of cell cycle process GO:0010564 160 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
locomotory behavior GO:0007626 195 0.013
cellular ion homeostasis GO:0006873 165 0.013
regulation of secretion by cell GO:1903530 249 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
single fertilization GO:0007338 82 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
sequestering of calcium ion GO:0051208 18 0.013
protein localization to nucleus GO:0034504 121 0.013
regulation of actin filament based process GO:0032970 99 0.013
anion transport GO:0006820 177 0.013
mitotic cell cycle process GO:1903047 159 0.013
metal ion homeostasis GO:0055065 189 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
renal system development GO:0072001 225 0.013
negative regulation of nervous system development GO:0051961 156 0.013
actin cytoskeleton organization GO:0030036 220 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
organophosphate catabolic process GO:0046434 232 0.012
spermatid differentiation GO:0048515 115 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
regionalization GO:0003002 337 0.012
cation homeostasis GO:0055080 212 0.012
neuron death GO:0070997 154 0.012
positive regulation of immune effector process GO:0002699 107 0.012
cellular protein complex assembly GO:0043623 116 0.012
regulation of response to wounding GO:1903034 189 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
divalent metal ion transport GO:0070838 172 0.012
macromolecule methylation GO:0043414 120 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
regulation of cellular component size GO:0032535 121 0.012
positive regulation of defense response GO:0031349 124 0.012
nucleoside metabolic process GO:0009116 246 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
Mouse Rat
mitotic cytokinesis GO:0000281 4 0.012
spermatid development GO:0007286 108 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
regulation of intracellular transport GO:0032386 159 0.012
multicellular organism growth GO:0035264 161 0.012
skeletal system development GO:0001501 356 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
adult locomotory behavior GO:0008344 91 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
calcium ion transport GO:0006816 159 0.012
regulation of protein processing GO:0070613 96 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
lymphocyte proliferation GO:0046651 164 0.011
ossification GO:0001503 216 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
cell adhesion GO:0007155 329 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
nucleoside catabolic process GO:0009164 206 0.011
alpha beta t cell activation GO:0046631 91 0.011
exocytosis GO:0006887 121 0.011
fatty acid metabolic process GO:0006631 121 0.011
action potential GO:0001508 78 0.011
germ cell development GO:0007281 185 0.011
cell activation involved in immune response GO:0002263 126 0.011
fat cell differentiation GO:0045444 160 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
wnt signaling pathway GO:0016055 188 0.011
chemotaxis GO:0006935 247 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
negative regulation of protein modification process GO:0031400 163 0.011
ear development GO:0043583 200 0.011
urogenital system development GO:0001655 261 0.011
multi multicellular organism process GO:0044706 109 0.011
telencephalon development GO:0021537 186 0.011
protein localization to membrane GO:0072657 108 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
establishment of organelle localization GO:0051656 122 0.011
regulation of neuron projection development GO:0010975 169 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
cellular response to lipid GO:0071396 145 0.011
skin development GO:0043588 220 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
nuclear transport GO:0051169 139 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of cytokine production GO:0001819 174 0.011
small molecule biosynthetic process GO:0044283 132 0.011
organic anion transport GO:0015711 137 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
cell growth GO:0016049 130 0.011
cell maturation GO:0048469 127 0.011
plasma membrane organization GO:0007009 90 0.011
chromatin organization GO:0006325 206 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
b cell activation GO:0042113 161 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
gliogenesis GO:0042063 141 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
mesodermal cell migration GO:0008078 4 0.010
limb development GO:0060173 166 0.010
heart morphogenesis GO:0003007 178 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
regulation of protein maturation GO:1903317 96 0.010
axon ensheathment GO:0008366 76 0.010
response to organic cyclic compound GO:0014070 198 0.010
lipid localization GO:0010876 126 0.010
lipid biosynthetic process GO:0008610 179 0.010
positive regulation of organelle organization GO:0010638 128 0.010
adaptive immune response GO:0002250 155 0.010
ensheathment of neurons GO:0007272 76 0.010
myelination GO:0042552 74 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
epithelial tube formation GO:0072175 130 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
viral gene expression GO:0019080 3 0.010
carboxylic acid transport GO:0046942 100 0.010
positive regulation of t cell activation GO:0050870 101 0.010
adult behavior GO:0030534 135 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
regulation of cell adhesion GO:0030155 154 0.010
regulation of adaptive immune response GO:0002819 90 0.010

Grk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
sensory system disease DOID:0050155 0 0.026
eye and adnexa disease DOID:1492 0 0.026
eye disease DOID:5614 0 0.024
retinal disease DOID:5679 0 0.022
musculoskeletal system disease DOID:17 0 0.020
central nervous system disease DOID:331 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
retinal degeneration DOID:8466 0 0.012
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011