Mus musculus

0 known processes

Plekhf2

pleckstrin homology domain containing, family F (with FYVE domain) member 2

(Aliases: 1110070J07Rik,ZFYVE18,AA673237)

Plekhf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.075
regulation of transferase activity GO:0051338 263 0.064
macromolecule catabolic process GO:0009057 281 0.062
protein modification by small protein conjugation GO:0032446 187 0.058
protein ubiquitination GO:0016567 171 0.058
amine metabolic process GO:0009308 45 0.053
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.053
cellular amine metabolic process GO:0044106 44 0.053
cellular macromolecule catabolic process GO:0044265 206 0.052
membrane organization GO:0061024 245 0.052
apoptotic signaling pathway GO:0097190 306 0.050
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.049
Mouse
cellular amino acid metabolic process GO:0006520 103 0.048
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
modification dependent macromolecule catabolic process GO:0043632 133 0.046
cellular lipid metabolic process GO:0044255 323 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
glycosyl compound catabolic process GO:1901658 206 0.043
proteasomal protein catabolic process GO:0010498 98 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.042
homeostasis of number of cells GO:0048872 210 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cation transport GO:0006812 399 0.039
protein catabolic process GO:0030163 221 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
cellular protein catabolic process GO:0044257 155 0.037
myeloid cell differentiation GO:0030099 233 0.036
modification dependent protein catabolic process GO:0019941 133 0.036
positive regulation of protein modification process GO:0031401 299 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
aromatic compound catabolic process GO:0019439 286 0.034
transmembrane transport GO:0055085 412 0.034
organic anion transport GO:0015711 137 0.033
nucleotide metabolic process GO:0009117 332 0.032
regulation of cell cycle GO:0051726 281 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
regulation of kinase activity GO:0043549 249 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
cellular response to dna damage stimulus GO:0006974 207 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
multicellular organism growth GO:0035264 161 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
response to oxidative stress GO:0006979 123 0.030
g protein coupled receptor signaling pathway GO:0007186 243 0.030
negative regulation of molecular function GO:0044092 258 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
cellular homeostasis GO:0019725 240 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
heterocycle catabolic process GO:0046700 280 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
cytoplasmic transport GO:0016482 234 0.029
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.029
nucleoside metabolic process GO:0009116 246 0.029
cellular ketone metabolic process GO:0042180 84 0.028
regulation of cell activation GO:0050865 289 0.028
carbohydrate metabolic process GO:0005975 230 0.028
regulation of organelle organization GO:0033043 289 0.028
purine containing compound metabolic process GO:0072521 311 0.027
purine containing compound catabolic process GO:0072523 213 0.027
regulation of protein kinase activity GO:0045859 232 0.027
cellular chemical homeostasis GO:0055082 215 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
cellular ion homeostasis GO:0006873 165 0.026
cation homeostasis GO:0055080 212 0.026
organophosphate catabolic process GO:0046434 232 0.026
membrane lipid biosynthetic process GO:0046467 32 0.026
negative regulation of phosphorylation GO:0042326 166 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
regulation of myeloid cell differentiation GO:0045637 96 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
regulation of membrane potential GO:0042391 192 0.025
compound eye development GO:0048749 1 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
cytokine production GO:0001816 319 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
anion transport GO:0006820 177 0.024
ras protein signal transduction GO:0007265 77 0.024
inorganic cation transmembrane transport GO:0098662 207 0.024
chromatin modification GO:0016568 187 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
cell type specific apoptotic process GO:0097285 268 0.024
cation transmembrane transport GO:0098655 266 0.023
wound healing GO:0042060 157 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
male gamete generation GO:0048232 285 0.023
covalent chromatin modification GO:0016569 163 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
respiratory system development GO:0060541 190 0.023
response to radiation GO:0009314 165 0.022
cellular response to lipid GO:0071396 145 0.022
regulation of protein localization GO:0032880 231 0.022
nucleotide catabolic process GO:0009166 217 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
peptidyl amino acid modification GO:0018193 336 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
erythrocyte differentiation GO:0030218 88 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
endomembrane system organization GO:0010256 147 0.022
Fly
cellular metal ion homeostasis GO:0006875 151 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
ion transmembrane transport GO:0034220 361 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
lipid biosynthetic process GO:0008610 179 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
dna metabolic process GO:0006259 303 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
cell adhesion GO:0007155 329 0.020
myeloid cell homeostasis GO:0002262 114 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
spermatogenesis GO:0007283 284 0.020
intracellular protein transport GO:0006886 204 0.020
chromatin organization GO:0006325 206 0.020
response to organonitrogen compound GO:0010243 246 0.020
divalent metal ion transport GO:0070838 172 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
muscle cell differentiation GO:0042692 261 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
embryonic epithelial tube formation GO:0001838 130 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
oxidation reduction process GO:0055114 342 0.019
sensory organ morphogenesis GO:0090596 242 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
nitrogen compound transport GO:0071705 271 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
negative regulation of immune system process GO:0002683 209 0.019
respiratory tube development GO:0030323 167 0.019
regulation of cell adhesion GO:0030155 154 0.019
response to acid chemical GO:0001101 111 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
organelle localization GO:0051640 179 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
histone modification GO:0016570 159 0.019
regulation of lymphocyte activation GO:0051249 240 0.018
skeletal system development GO:0001501 356 0.018
regulation of body fluid levels GO:0050878 162 0.018
organelle fission GO:0048285 170 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
mitochondrion organization GO:0007005 134 0.018
dephosphorylation GO:0016311 129 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
b cell activation GO:0042113 161 0.018
positive regulation of cell development GO:0010720 237 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
asymmetric stem cell division GO:0098722 3 0.018
spermatid development GO:0007286 108 0.018
regulation of cytokine production GO:0001817 266 0.018
hemostasis GO:0007599 78 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
cytokine mediated signaling pathway GO:0019221 115 0.017
regulation of cellular response to stress GO:0080135 159 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of ion transport GO:0043269 215 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
blood coagulation GO:0007596 76 0.017
blood vessel morphogenesis GO:0048514 285 0.017
organophosphate ester transport GO:0015748 28 0.017
regulation of cell migration GO:0030334 219 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
limb morphogenesis GO:0035108 149 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
regulation of neuron differentiation GO:0045664 281 0.017
fat cell differentiation GO:0045444 160 0.017
regulation of defense response GO:0031347 233 0.017
coagulation GO:0050817 78 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
neuronal action potential GO:0019228 54 0.016
stem cell differentiation GO:0048863 268 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
sensory perception GO:0007600 245 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of mapk cascade GO:0043408 248 0.016
synaptic transmission GO:0007268 329 0.016
regulation of cell motility GO:2000145 236 0.016
glycosylation GO:0070085 62 0.016
inflammatory response GO:0006954 244 0.016
mapk cascade GO:0000165 281 0.016
action potential GO:0001508 78 0.016
response to light stimulus GO:0009416 135 0.016
t cell activation GO:0042110 289 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
metal ion homeostasis GO:0055065 189 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
innate immune response GO:0045087 157 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
negative regulation of nervous system development GO:0051961 156 0.015
regulation of cell projection organization GO:0031344 206 0.015
negative regulation of protein modification process GO:0031400 163 0.015
response to extracellular stimulus GO:0009991 127 0.015
transmission of nerve impulse GO:0019226 76 0.015
digestive system development GO:0055123 200 0.015
regulation of anatomical structure size GO:0090066 178 0.015
rhythmic process GO:0048511 174 0.015
divalent inorganic cation transport GO:0072511 178 0.015
response to nutrient levels GO:0031667 109 0.015
multicellular organismal signaling GO:0035637 91 0.015
camera type eye development GO:0043010 266 0.015
sequestering of metal ion GO:0051238 19 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
spermatid differentiation GO:0048515 115 0.015
dna endoreduplication GO:0042023 4 0.015
protein maturation GO:0051604 176 0.015
calcium ion homeostasis GO:0055074 127 0.015
immune response activating signal transduction GO:0002757 116 0.015
lipid transport GO:0006869 98 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
response to lipopolysaccharide GO:0032496 128 0.015
regulation of secretion GO:0051046 274 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
positive regulation of kinase activity GO:0033674 155 0.015
leukocyte differentiation GO:0002521 342 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
regulation of system process GO:0044057 200 0.015
digestive tract development GO:0048565 190 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
Mouse
regulation of response to wounding GO:1903034 189 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.014
muscle tissue development GO:0060537 308 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
cellularization GO:0007349 1 0.014
regulation of secretion by cell GO:1903530 249 0.014
forebrain development GO:0030900 302 0.014
interleukin 8 production GO:0032637 4 0.014
protein glycosylation GO:0006486 55 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
stem cell maintenance GO:0019827 130 0.014
regulation of proteolysis GO:0030162 164 0.014
negative regulation of kinase activity GO:0033673 81 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
angiogenesis GO:0001525 201 0.014
immune effector process GO:0002252 321 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
Mouse
regulation of inflammatory response GO:0050727 147 0.014
blood circulation GO:0008015 195 0.014
blastocyst development GO:0001824 80 0.014
oocyte construction GO:0007308 2 0.014
positive regulation of cell death GO:0010942 224 0.014
Mouse
limb development GO:0060173 166 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
Mouse
membrane lipid metabolic process GO:0006643 53 0.014
monosaccharide metabolic process GO:0005996 106 0.014
regulation of hydrolase activity GO:0051336 246 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
regulation of hormone levels GO:0010817 211 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.013
epithelial cell development GO:0002064 159 0.013
regulation of t cell activation GO:0050863 170 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
neural tube development GO:0021915 160 0.013
glycerolipid metabolic process GO:0046486 122 0.013
skeletal muscle organ development GO:0060538 163 0.013
urogenital system development GO:0001655 261 0.013
stem cell development GO:0048864 219 0.013
positive regulation of transferase activity GO:0051347 167 0.013
nuclear division GO:0000280 158 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
calcium ion transport GO:0006816 159 0.013
regulation of cell cycle process GO:0010564 160 0.013
cytokine secretion GO:0050663 72 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
response to organic cyclic compound GO:0014070 198 0.013
neural tube formation GO:0001841 108 0.013
sequestering of calcium ion GO:0051208 18 0.013
regulation of cell shape GO:0008360 39 0.013
regulation of protein transport GO:0051223 163 0.013
negative regulation of transferase activity GO:0051348 85 0.013
regulation of protein catabolic process GO:0042176 108 0.013
germ cell development GO:0007281 185 0.013
rna interference GO:0016246 2 0.013
microtubule based process GO:0007017 236 0.013
sphingolipid metabolic process GO:0006665 45 0.013
mitotic cell cycle GO:0000278 195 0.013
mitotic cell cycle process GO:1903047 159 0.012
lung development GO:0030324 164 0.012
positive regulation of cell activation GO:0050867 158 0.012
protein polyubiquitination GO:0000209 33 0.012
single organism cell adhesion GO:0098602 156 0.012
macromolecule glycosylation GO:0043413 55 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
asymmetric neuroblast division GO:0055059 1 0.012
regulation of clathrin mediated endocytosis GO:2000369 4 0.012
ossification GO:0001503 216 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
glycoprotein metabolic process GO:0009100 116 0.012
gland development GO:0048732 330 0.012
methylation GO:0032259 134 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
carbohydrate transport GO:0008643 62 0.012
actin cytoskeleton organization GO:0030036 220 0.012
activation of adenylate cyclase activity GO:0007190 4 0.012
striated muscle tissue development GO:0014706 293 0.012
protein autophosphorylation GO:0046777 61 0.012
epithelial tube formation GO:0072175 130 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.012
lipid localization GO:0010876 126 0.012
protein processing GO:0016485 163 0.012
skin development GO:0043588 220 0.012
rho protein signal transduction GO:0007266 32 0.011
response to inorganic substance GO:0010035 96 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
circulatory system process GO:0003013 197 0.011
protein oligomerization GO:0051259 67 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
negative regulation of cell development GO:0010721 169 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
mrna metabolic process GO:0016071 84 0.011
positive regulation of cytokine production GO:0001819 174 0.011
gliogenesis GO:0042063 141 0.011
skeletal system morphogenesis GO:0048705 203 0.011
hormone secretion GO:0046879 128 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
connective tissue development GO:0061448 179 0.011
cellular response to acid chemical GO:0071229 68 0.011
meiosis i GO:0007127 60 0.011
maintenance of location GO:0051235 89 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
sphingolipid biosynthetic process GO:0030148 26 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
regulation of metal ion transport GO:0010959 106 0.011
kidney development GO:0001822 213 0.011
positive regulation of secretion GO:0051047 130 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
rna processing GO:0006396 105 0.011
regulation of protein complex assembly GO:0043254 83 0.011
lymphocyte homeostasis GO:0002260 64 0.011
cell growth GO:0016049 130 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
membrane depolarization GO:0051899 64 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
positive regulation of organelle organization GO:0010638 128 0.011
male gonad development GO:0008584 88 0.011
b cell differentiation GO:0030183 78 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
megakaryocyte differentiation GO:0030219 26 0.011
macromolecule methylation GO:0043414 120 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.011
myotube differentiation GO:0014902 105 0.011
negative regulation of inflammatory response GO:0050728 61 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
protein localization to organelle GO:0033365 185 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
tube formation GO:0035148 140 0.011
protein localization to nucleus GO:0034504 121 0.011
nucleotide sugar transport GO:0015780 2 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
oocyte axis specification GO:0007309 2 0.010
carbohydrate homeostasis GO:0033500 128 0.010
endocytosis GO:0006897 168 0.010
Fly
ear development GO:0043583 200 0.010
muscle system process GO:0003012 141 0.010
myosin filament assembly GO:0031034 2 0.010
positive regulation of nervous system development GO:0051962 221 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
regulation of neuron death GO:1901214 134 0.010
mrna processing GO:0006397 63 0.010
placenta development GO:0001890 140 0.010
negative regulation of cell activation GO:0050866 111 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
peptidyl lysine modification GO:0018205 77 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
organic acid transport GO:0015849 101 0.010
neural precursor cell proliferation GO:0061351 121 0.010
protein secretion GO:0009306 111 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
regulation of transmembrane transport GO:0034762 128 0.010
cellular protein complex assembly GO:0043623 116 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
regulation of b cell activation GO:0050864 81 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
establishment of vesicle localization GO:0051650 81 0.010
regulation of chromosome organization GO:0033044 83 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
protein localization to membrane GO:0072657 108 0.010
bone development GO:0060348 120 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
protein polymerization GO:0051258 57 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
protein targeting GO:0006605 143 0.010

Plekhf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
central nervous system disease DOID:331 0 0.020
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.013
sensory system disease DOID:0050155 0 0.011
immune system disease DOID:2914 0 0.010
neurodegenerative disease DOID:1289 0 0.010