Mus musculus

36 known processes

Suv420h1

suppressor of variegation 4-20 homolog 1 (Drosophila)

(Aliases: KMT5B,AA117471,MGC18702,C630029K18Rik,Suv4-20h1)

Suv420h1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.104
chromatin modification GO:0016568 187 0.097
covalent chromatin modification GO:0016569 163 0.093
ras protein signal transduction GO:0007265 77 0.091
regulation of organelle organization GO:0033043 289 0.091
cellular amino acid metabolic process GO:0006520 103 0.083
peptidyl amino acid modification GO:0018193 336 0.080
histone methylation GO:0016571 71 0.078
amine metabolic process GO:0009308 45 0.076
protein methylation GO:0006479 81 0.075
macromolecule catabolic process GO:0009057 281 0.072
cellular amine metabolic process GO:0044106 44 0.070
regulation of cellular amine metabolic process GO:0033238 20 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.068
regulation of cell cycle GO:0051726 281 0.064
cellular ketone metabolic process GO:0042180 84 0.063
negative regulation of protein metabolic process GO:0051248 282 0.058
myeloid cell differentiation GO:0030099 233 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
muscle cell differentiation GO:0042692 261 0.051
small gtpase mediated signal transduction GO:0007264 97 0.050
histone modification GO:0016570 159 0.049
histone lysine methylation GO:0034968 50 0.049
mitotic cell cycle process GO:1903047 159 0.048
protein localization to organelle GO:0033365 185 0.047
negative regulation of protein modification process GO:0031400 163 0.047
cellular response to dna damage stimulus GO:0006974 207 0.046
macromolecule methylation GO:0043414 120 0.046
modification dependent macromolecule catabolic process GO:0043632 133 0.046
regulation of protein localization GO:0032880 231 0.045
chromatin organization GO:0006325 206 0.044
regulation of transferase activity GO:0051338 263 0.044
regulation of histone methylation GO:0031060 30 0.042
leukocyte differentiation GO:0002521 342 0.041
positive regulation of protein phosphorylation GO:0001934 242 0.041
methylation GO:0032259 134 0.039
apoptotic signaling pathway GO:0097190 306 0.039
negative regulation of cell proliferation GO:0008285 296 0.037
cellular macromolecule catabolic process GO:0044265 206 0.036
cell type specific apoptotic process GO:0097285 268 0.036
protein modification by small protein conjugation GO:0032446 187 0.036
peptidyl lysine modification GO:0018205 77 0.036
negative regulation of molecular function GO:0044092 258 0.036
negative regulation of phosphorylation GO:0042326 166 0.036
positive regulation of protein modification process GO:0031401 299 0.035
cell adhesion GO:0007155 329 0.035
regulation of kinase activity GO:0043549 249 0.034
regulation of cellular response to stress GO:0080135 159 0.034
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 3 0.034
homeostasis of number of cells GO:0048872 210 0.034
male gamete generation GO:0048232 285 0.033
spermatogenesis GO:0007283 284 0.033
cellular response to organonitrogen compound GO:0071417 145 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.033
heterocycle catabolic process GO:0046700 280 0.032
actin cytoskeleton organization GO:0030036 220 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
stem cell differentiation GO:0048863 268 0.031
organelle localization GO:0051640 179 0.031
muscle tissue development GO:0060537 308 0.030
nuclear division GO:0000280 158 0.029
negative regulation of cellular amine metabolic process GO:0033239 1 0.029
cation transport GO:0006812 399 0.029
organelle fission GO:0048285 170 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
protein catabolic process GO:0030163 221 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.028
intrinsic apoptotic signaling pathway GO:0097193 132 0.028
regulation of neuron differentiation GO:0045664 281 0.028
cytokine production GO:0001816 319 0.027
negative regulation of immune system process GO:0002683 209 0.027
protein ubiquitination GO:0016567 171 0.027
regulation of cell activation GO:0050865 289 0.027
positive regulation of organelle organization GO:0010638 128 0.027
transmembrane transport GO:0055085 412 0.027
chromosome segregation GO:0007059 48 0.026
regulation of ras protein signal transduction GO:0046578 114 0.026
t cell activation GO:0042110 289 0.026
regulation of cellular catabolic process GO:0031329 242 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of cell cycle process GO:0010564 160 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
proteasomal protein catabolic process GO:0010498 98 0.024
neuron death GO:0070997 154 0.024
positive regulation of nervous system development GO:0051962 221 0.024
rho protein signal transduction GO:0007266 32 0.024
protein alkylation GO:0008213 81 0.024
regulation of protein kinase activity GO:0045859 232 0.024
regulation of actin filament based process GO:0032970 99 0.023
peptidyl lysine methylation GO:0018022 29 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.023
regulation of cellular component biogenesis GO:0044087 181 0.022
purine containing compound metabolic process GO:0072521 311 0.022
regulation of gtp catabolic process GO:0033124 113 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
digestive system development GO:0055123 200 0.022
glial cell apoptotic process GO:0034349 3 0.022
digestive tract morphogenesis GO:0048546 147 0.022
actin filament organization GO:0007015 113 0.022
gene silencing GO:0016458 38 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
regionalization GO:0003002 337 0.022
positive regulation of transferase activity GO:0051347 167 0.021
response to organonitrogen compound GO:0010243 246 0.021
rhythmic process GO:0048511 174 0.021
regulation of myeloid leukocyte differentiation GO:0002761 58 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
protein localization to nucleus GO:0034504 121 0.021
positive regulation of leukocyte differentiation GO:1902107 86 0.021
mitotic cell cycle GO:0000278 195 0.020
cellular protein catabolic process GO:0044257 155 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
regulation of chromosome organization GO:0033044 83 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
regulation of defense response GO:0031347 233 0.020
regulation of cytokine production GO:0001817 266 0.020
cytoplasmic transport GO:0016482 234 0.020
regulation of binding GO:0051098 111 0.020
positive regulation of kinase activity GO:0033674 155 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of actin cytoskeleton organization GO:0032956 84 0.020
regulation of myeloid cell differentiation GO:0045637 96 0.020
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
negative regulation of cell cycle GO:0045786 123 0.019
cellular homeostasis GO:0019725 240 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
cation transmembrane transport GO:0098655 266 0.019
circulatory system process GO:0003013 197 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
striated muscle tissue development GO:0014706 293 0.019
dendrite development GO:0016358 115 0.019
immune effector process GO:0002252 321 0.019
germ cell development GO:0007281 185 0.019
dephosphorylation GO:0016311 129 0.019
skeletal muscle organ development GO:0060538 163 0.019
circadian rhythm GO:0007623 114 0.019
positive regulation of apoptotic process GO:0043065 217 0.018
regulation of cell projection organization GO:0031344 206 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
muscle system process GO:0003012 141 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
blood circulation GO:0008015 195 0.018
establishment of organelle localization GO:0051656 122 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
nitrogen compound transport GO:0071705 271 0.018
myeloid cell homeostasis GO:0002262 114 0.018
peptidyl serine modification GO:0018209 83 0.018
aromatic compound catabolic process GO:0019439 286 0.017
rna processing GO:0006396 105 0.017
regulation of mapk cascade GO:0043408 248 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
forebrain development GO:0030900 302 0.017
positive regulation of cytokine production GO:0001819 174 0.017
smoothened signaling pathway GO:0007224 105 0.017
nucleotide catabolic process GO:0009166 217 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
carbohydrate metabolic process GO:0005975 230 0.017
gtp catabolic process GO:0006184 143 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
digestive tract development GO:0048565 190 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
mitotic nuclear division GO:0007067 48 0.017
regulation of cell motility GO:2000145 236 0.017
positive regulation of cell development GO:0010720 237 0.017
regulation of chromatin organization GO:1902275 57 0.016
maintenance of location GO:0051235 89 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
nuclear transport GO:0051169 139 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
regulation of secretion by cell GO:1903530 249 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
response to lipopolysaccharide GO:0032496 128 0.016
immune response activating signal transduction GO:0002757 116 0.016
regulation of multi organism process GO:0043900 111 0.016
membrane organization GO:0061024 245 0.016
dna metabolic process GO:0006259 303 0.016
regulation of neuron projection development GO:0010975 169 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
developmental maturation GO:0021700 193 0.016
respiratory system development GO:0060541 190 0.016
respiratory tube development GO:0030323 167 0.016
ribonucleoside catabolic process GO:0042454 206 0.015
cell cycle g1 s phase transition GO:0044843 57 0.015
response to peptide GO:1901652 136 0.015
nucleotide metabolic process GO:0009117 332 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
epithelial cell proliferation GO:0050673 174 0.015
neuron apoptotic process GO:0051402 142 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
regulation of cohesin localization to chromatin GO:0071922 1 0.015
regulation of secretion GO:0051046 274 0.015
stem cell development GO:0048864 219 0.015
regulation of t cell activation GO:0050863 170 0.015
regulation of chromatin modification GO:1903308 57 0.015
nucleoside metabolic process GO:0009116 246 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
cellular lipid metabolic process GO:0044255 323 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
asymmetric stem cell division GO:0098722 3 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
purine containing compound catabolic process GO:0072523 213 0.015
regulation of intracellular transport GO:0032386 159 0.015
cell division GO:0051301 120 0.015
cell substrate adhesion GO:0031589 130 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
regulation of system process GO:0044057 200 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
cellular response to peptide GO:1901653 92 0.015
regulation of hydrolase activity GO:0051336 246 0.015
erythrocyte differentiation GO:0030218 88 0.015
cell maturation GO:0048469 127 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
regulation of histone modification GO:0031056 56 0.015
heart morphogenesis GO:0003007 178 0.015
regulation of smoothened signaling pathway GO:0008589 58 0.015
regulation of establishment of protein localization GO:0070201 181 0.014
organophosphate catabolic process GO:0046434 232 0.014
gtp metabolic process GO:0046039 144 0.014
endocytosis GO:0006897 168 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
divalent inorganic cation transport GO:0072511 178 0.014
microtubule based process GO:0007017 236 0.014
adaptive immune response GO:0002250 155 0.014
signal transduction by p53 class mediator GO:0072331 51 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
multicellular organism growth GO:0035264 161 0.014
Zebrafish
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
b cell activation GO:0042113 161 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
angiogenesis GO:0001525 201 0.014
protein localization to chromatin GO:0071168 3 0.014
response to radiation GO:0009314 165 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
mrna metabolic process GO:0016071 84 0.014
lymphocyte differentiation GO:0030098 242 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
regulation of membrane potential GO:0042391 192 0.014
skeletal muscle cell differentiation GO:0035914 66 0.014
sensory perception GO:0007600 245 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
regulation of anatomical structure size GO:0090066 178 0.014
response to acid chemical GO:0001101 111 0.014
regulation of hormone levels GO:0010817 211 0.014
myotube differentiation GO:0014902 105 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
cohesin localization to chromatin GO:0071921 1 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
blood vessel morphogenesis GO:0048514 285 0.013
compound eye development GO:0048749 1 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
synaptic transmission GO:0007268 329 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
ion transmembrane transport GO:0034220 361 0.013
response to growth factor GO:0070848 198 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
tube formation GO:0035148 140 0.013
histone acetylation GO:0016573 41 0.013
oxidation reduction process GO:0055114 342 0.013
synapse organization GO:0050808 125 0.013
response to light stimulus GO:0009416 135 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of proteolysis GO:0030162 164 0.013
cellular response to acid chemical GO:0071229 68 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
inflammatory response GO:0006954 244 0.013
single organism cell adhesion GO:0098602 156 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
nucleoside catabolic process GO:0009164 206 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
negative regulation of dna replication GO:0008156 4 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
response to peptide hormone GO:0043434 127 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
asymmetric neuroblast division GO:0055059 1 0.012
exocytosis GO:0006887 121 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
negative regulation of cell activation GO:0050866 111 0.012
mapk cascade GO:0000165 281 0.012
spermatid differentiation GO:0048515 115 0.012
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.012
divalent metal ion transport GO:0070838 172 0.012
multi organism behavior GO:0051705 62 0.012
protein oligomerization GO:0051259 67 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
peptide transport GO:0015833 133 0.012
cellular response to external stimulus GO:0071496 88 0.012
regulation of transmembrane transport GO:0034762 128 0.012
hindbrain development GO:0030902 128 0.012
regulation of protein transport GO:0051223 163 0.012
cellular protein complex assembly GO:0043623 116 0.012
cellular chemical homeostasis GO:0055082 215 0.012
negative regulation of nervous system development GO:0051961 156 0.012
renal system development GO:0072001 225 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
single organism nuclear import GO:1902593 95 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of ion transport GO:0043269 215 0.012
defense response to other organism GO:0098542 197 0.012
negative regulation of organelle organization GO:0010639 90 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
mrna processing GO:0006397 63 0.011
action potential GO:0001508 78 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
body morphogenesis GO:0010171 45 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
multicellular organismal signaling GO:0035637 91 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
calcium ion transport GO:0006816 159 0.011
mitotic sister chromatid cohesion GO:0007064 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
cellular response to lipid GO:0071396 145 0.011
tissue homeostasis GO:0001894 115 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
negative regulation of protein transport GO:0051224 46 0.011
neural tube development GO:0021915 160 0.011
leukocyte proliferation GO:0070661 172 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
g1 s transition of mitotic cell cycle GO:0000082 57 0.011
peptidyl threonine phosphorylation GO:0018107 31 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
cardiac chamber development GO:0003205 108 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
endodermal cell fate specification GO:0001714 4 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
vesicle localization GO:0051648 86 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
response to insulin GO:0032868 100 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of cellular component size GO:0032535 121 0.011
glycoprotein metabolic process GO:0009100 116 0.011
hormone secretion GO:0046879 128 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
wound healing GO:0042060 157 0.010
activation of immune response GO:0002253 138 0.010
embryonic placenta development GO:0001892 98 0.010
protein targeting GO:0006605 143 0.010
placenta development GO:0001890 140 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
protein acylation GO:0043543 64 0.010
camera type eye development GO:0043010 266 0.010
glycerolipid metabolic process GO:0046486 122 0.010
internal peptidyl lysine acetylation GO:0018393 42 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
multi multicellular organism process GO:0044706 109 0.010
spermatid development GO:0007286 108 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
negative regulation of smoothened signaling pathway GO:0045879 25 0.010
cardiac ventricle development GO:0003231 83 0.010
regulation of feeding behavior GO:0060259 3 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
peptide secretion GO:0002790 114 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
small molecule biosynthetic process GO:0044283 132 0.010
myosin filament assembly GO:0031034 2 0.010
response to monosaccharide GO:0034284 67 0.010
regulation of neuron death GO:1901214 134 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.010
regulation of chromatin silencing GO:0031935 2 0.010
gonad development GO:0008406 141 0.010

Suv420h1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.013