Mus musculus

0 known processes

Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

(Aliases: MLC,WKL1,mKIAA0027,VL,AW048630,BB074274,Kiaa0027-hp,LVM)

Mlc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuronal action potential GO:0019228 54 0.096
anion transmembrane transport GO:0098656 71 0.092
carboxylic acid transport GO:0046942 100 0.090
ion transmembrane transport GO:0034220 361 0.089
synaptic transmission GO:0007268 329 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.082
organic cyclic compound catabolic process GO:1901361 295 0.077
cellular amino acid metabolic process GO:0006520 103 0.076
action potential GO:0001508 78 0.069
organic anion transport GO:0015711 137 0.068
amino acid transport GO:0006865 61 0.064
aromatic compound catabolic process GO:0019439 286 0.061
cellular ketone metabolic process GO:0042180 84 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.056
cellular amine metabolic process GO:0044106 44 0.055
cellular nitrogen compound catabolic process GO:0044270 280 0.054
organonitrogen compound catabolic process GO:1901565 264 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.053
purine nucleotide metabolic process GO:0006163 302 0.052
amino acid transmembrane transport GO:0003333 37 0.051
myelination GO:0042552 74 0.050
transmission of nerve impulse GO:0019226 76 0.050
organic acid transport GO:0015849 101 0.050
nitrogen compound transport GO:0071705 271 0.050
transmembrane transport GO:0055085 412 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.048
purine ribonucleotide catabolic process GO:0009154 208 0.048
purine nucleoside triphosphate metabolic process GO:0009144 226 0.047
small gtpase mediated signal transduction GO:0007264 97 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
regulation of membrane potential GO:0042391 192 0.045
nucleotide catabolic process GO:0009166 217 0.045
purine nucleoside metabolic process GO:0042278 241 0.044
multicellular organismal signaling GO:0035637 91 0.043
purine ribonucleotide metabolic process GO:0009150 290 0.042
membrane organization GO:0061024 245 0.040
ensheathment of neurons GO:0007272 76 0.040
ribonucleoside catabolic process GO:0042454 206 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
purine containing compound catabolic process GO:0072523 213 0.040
nucleoside triphosphate metabolic process GO:0009141 230 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.038
heterocycle catabolic process GO:0046700 280 0.038
nucleoside phosphate catabolic process GO:1901292 222 0.038
ras protein signal transduction GO:0007265 77 0.037
nucleotide metabolic process GO:0009117 332 0.037
amine metabolic process GO:0009308 45 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
response to organonitrogen compound GO:0010243 246 0.037
glycosyl compound catabolic process GO:1901658 206 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
regulation of ion transport GO:0043269 215 0.036
ribonucleotide catabolic process GO:0009261 208 0.034
l amino acid transport GO:0015807 32 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.032
nucleoside metabolic process GO:0009116 246 0.032
cation transmembrane transport GO:0098655 266 0.031
mapk cascade GO:0000165 281 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
organophosphate catabolic process GO:0046434 232 0.030
g protein coupled receptor signaling pathway GO:0007186 243 0.029
axon ensheathment GO:0008366 76 0.029
exocytosis GO:0006887 121 0.029
cation transport GO:0006812 399 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
monocarboxylic acid metabolic process GO:0032787 191 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
cytoplasmic transport GO:0016482 234 0.028
lipid biosynthetic process GO:0008610 179 0.028
organelle fission GO:0048285 170 0.028
muscle cell differentiation GO:0042692 261 0.028
regulation of gtp catabolic process GO:0033124 113 0.028
positive regulation of cell development GO:0010720 237 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
cell adhesion GO:0007155 329 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
response to acid chemical GO:0001101 111 0.026
purine nucleotide catabolic process GO:0006195 211 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
cellular lipid metabolic process GO:0044255 323 0.026
negative regulation of cell proliferation GO:0008285 296 0.025
muscle system process GO:0003012 141 0.025
macromolecule catabolic process GO:0009057 281 0.025
regulation of mapk cascade GO:0043408 248 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
regulation of transferase activity GO:0051338 263 0.023
glycoprotein metabolic process GO:0009100 116 0.023
intracellular protein transport GO:0006886 204 0.022
positive regulation of transferase activity GO:0051347 167 0.022
response to extracellular stimulus GO:0009991 127 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
cytokine production GO:0001816 319 0.022
regulation of cell activation GO:0050865 289 0.021
anion transport GO:0006820 177 0.021
nucleoside catabolic process GO:0009164 206 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
regulation of protein kinase activity GO:0045859 232 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
sodium ion transmembrane transport GO:0035725 49 0.020
response to organic cyclic compound GO:0014070 198 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
peptidyl amino acid modification GO:0018193 336 0.020
gtp catabolic process GO:0006184 143 0.020
ventricular cardiac muscle cell action potential GO:0086005 4 0.020
regulation of protein localization GO:0032880 231 0.020
muscle tissue development GO:0060537 308 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
purine containing compound metabolic process GO:0072521 311 0.020
cellular response to lipid GO:0071396 145 0.020
c4 dicarboxylate transport GO:0015740 3 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
cardiac muscle contraction GO:0060048 32 0.020
monosaccharide transport GO:0015749 58 0.020
glycoprotein biosynthetic process GO:0009101 89 0.020
regulation of nucleoside metabolic process GO:0009118 130 0.019
regulation of kinase activity GO:0043549 249 0.019
response to nutrient levels GO:0031667 109 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
regulation of neuron differentiation GO:0045664 281 0.019
positive regulation of nervous system development GO:0051962 221 0.019
muscle contraction GO:0006936 101 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
sodium ion transport GO:0006814 73 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.018
actin filament based movement GO:0030048 23 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
skeletal system development GO:0001501 356 0.018
regulation of secretion GO:0051046 274 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of intracellular transport GO:0032386 159 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
positive regulation of protein modification process GO:0031401 299 0.017
protein localization to organelle GO:0033365 185 0.017
response to light stimulus GO:0009416 135 0.017
immune effector process GO:0002252 321 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
regulation of anatomical structure size GO:0090066 178 0.017
carbohydrate metabolic process GO:0005975 230 0.017
regulation of cell projection organization GO:0031344 206 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
organic hydroxy compound transport GO:0015850 93 0.016
sensory perception GO:0007600 245 0.016
protein localization to membrane GO:0072657 108 0.016
nuclear division GO:0000280 158 0.016
neuron neuron synaptic transmission GO:0007270 69 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
cell substrate adhesion GO:0031589 130 0.016
rho protein signal transduction GO:0007266 32 0.016
regulation of cell cycle GO:0051726 281 0.016
negative regulation of molecular function GO:0044092 258 0.016
maternal determination of anterior posterior axis embryo GO:0008358 2 0.016
l alpha amino acid transmembrane transport GO:1902475 23 0.016
regulation of cellular response to stress GO:0080135 159 0.016
cardiac muscle cell contraction GO:0086003 7 0.016
lymphocyte differentiation GO:0030098 242 0.016
av node cell to bundle of his cell communication GO:0086067 2 0.016
cellular homeostasis GO:0019725 240 0.015
telencephalon development GO:0021537 186 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
sulfur compound metabolic process GO:0006790 100 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
regulation of postsynaptic membrane potential GO:0060078 48 0.015
actin mediated cell contraction GO:0070252 15 0.015
myotube differentiation GO:0014902 105 0.015
fat cell differentiation GO:0045444 160 0.015
germ cell development GO:0007281 185 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
response to retinoic acid GO:0032526 56 0.015
oocyte construction GO:0007308 2 0.015
meiotic cell cycle GO:0051321 122 0.015
microtubule based process GO:0007017 236 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
protein targeting GO:0006605 143 0.015
protein catabolic process GO:0030163 221 0.015
male gamete generation GO:0048232 285 0.015
single organism nuclear import GO:1902593 95 0.015
camera type eye development GO:0043010 266 0.015
oocyte axis specification GO:0007309 2 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
endocytosis GO:0006897 168 0.014
oxidation reduction process GO:0055114 342 0.014
regulation of tissue remodeling GO:0034103 38 0.014
positive regulation of protein transport GO:0051222 93 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.014
mesodermal cell migration GO:0008078 4 0.014
intracellular mrna localization GO:0008298 4 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
regulation of blood circulation GO:1903522 93 0.014
regulation of cell migration GO:0030334 219 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
multicellular organism growth GO:0035264 161 0.014
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 0.014
regulation of hormone levels GO:0010817 211 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
glycerolipid metabolic process GO:0046486 122 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
midgut development GO:0007494 4 0.014
milk ejection GO:0060156 1 0.014
neuron death GO:0070997 154 0.014
cellular response to acid chemical GO:0071229 68 0.013
meiotic nuclear division GO:0007126 115 0.013
sa node cell action potential GO:0086015 4 0.013
pole plasm assembly GO:0007315 2 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
cytokine secretion GO:0050663 72 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
gtp metabolic process GO:0046039 144 0.013
synapse organization GO:0050808 125 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
adult behavior GO:0030534 135 0.013
nuclear transport GO:0051169 139 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
neurotransmitter transport GO:0006836 76 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
dicarboxylic acid transport GO:0006835 29 0.013
neuron apoptotic process GO:0051402 142 0.013
regulation of protein transport GO:0051223 163 0.013
adult locomotory behavior GO:0008344 91 0.013
positive regulation of kinase activity GO:0033674 155 0.013
amide transport GO:0042886 138 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
interleukin 8 secretion GO:0072606 3 0.012
negative regulation of neuron differentiation GO:0045665 101 0.012
regulation of transmembrane transport GO:0034762 128 0.012
mitochondrion organization GO:0007005 134 0.012
negative regulation of membrane potential GO:0045837 4 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
positive regulation of ras gtpase activity GO:0032320 65 0.012
regulation of protein processing GO:0070613 96 0.012
rac protein signal transduction GO:0016601 13 0.012
mitotic cytokinesis GO:0000281 4 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
regulation of cell adhesion GO:0030155 154 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
circulatory system process GO:0003013 197 0.012
retina development in camera type eye GO:0060041 119 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
acid secretion GO:0046717 33 0.012
response to oxidative stress GO:0006979 123 0.012
carbohydrate transport GO:0008643 62 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
regulation of secretion by cell GO:1903530 249 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
maintenance of location GO:0051235 89 0.012
spermatogenesis GO:0007283 284 0.012
cellular response to external stimulus GO:0071496 88 0.012
inorganic anion transmembrane transport GO:0098661 29 0.012
regulation of muscle contraction GO:0006937 49 0.012
membrane lipid biosynthetic process GO:0046467 32 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
mitotic cell cycle GO:0000278 195 0.012
rna interference GO:0016246 2 0.012
establishment of blood nerve barrier GO:0008065 3 0.012
peptidyl serine modification GO:0018209 83 0.012
rap protein signal transduction GO:0032486 3 0.012
vascular process in circulatory system GO:0003018 62 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
protein secretion GO:0009306 111 0.011
regulation of ion homeostasis GO:2000021 64 0.011
cognition GO:0050890 149 0.011
multi multicellular organism process GO:0044706 109 0.011
blood vessel morphogenesis GO:0048514 285 0.011
sequestering of metal ion GO:0051238 19 0.011
atrial ventricular junction remodeling GO:0003294 2 0.011
organelle localization GO:0051640 179 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of cytokine production GO:0001817 266 0.011
glycerolipid biosynthetic process GO:0045017 50 0.011
cellular response to oxidative stress GO:0034599 76 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
vesicle organization GO:0016050 60 0.011
forebrain development GO:0030900 302 0.011
regulation of hydrolase activity GO:0051336 246 0.011
carbohydrate homeostasis GO:0033500 128 0.011
innate immune response GO:0045087 157 0.011
regulation of renin secretion into blood stream GO:1900133 4 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
negative regulation of growth GO:0045926 99 0.011
negative regulation of cell development GO:0010721 169 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of map kinase activity GO:0043405 120 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
cation homeostasis GO:0055080 212 0.011
sphingolipid biosynthetic process GO:0030148 26 0.011
regulation of bone remodeling GO:0046850 28 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
response to radiation GO:0009314 165 0.011
interleukin 8 production GO:0032637 4 0.011
glutamate biosynthetic process GO:0006537 2 0.011
myeloid cell differentiation GO:0030099 233 0.011
t cell activation GO:0042110 289 0.011
regulation of organelle organization GO:0033043 289 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
negative regulation of phagocytosis GO:0050765 4 0.010
bone resorption GO:0045453 38 0.010
dna metabolic process GO:0006259 303 0.010
establishment of protein localization to vacuole GO:0072666 4 0.010
photoreceptor cell differentiation GO:0046530 52 0.010
d amino acid transport GO:0042940 1 0.010
response to drug GO:0042493 75 0.010
t cell differentiation GO:0030217 174 0.010
photoreceptor cell morphogenesis GO:0008594 3 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
foramen ovale closure GO:0035922 1 0.010
regulation of ion transmembrane transporter activity GO:0032412 54 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
response to lipopolysaccharide GO:0032496 128 0.010
sphingosine 1 phosphate signaling pathway GO:0003376 3 0.010
protein oligomerization GO:0051259 67 0.010
regulation of protein maturation GO:1903317 96 0.010

Mlc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.025
neuromuscular disease DOID:440 0 0.013
neuropathy DOID:870 0 0.013
neurodegenerative disease DOID:1289 0 0.012
sensory system disease DOID:0050155 0 0.011