Mus musculus

52 known processes

Ptbp1

polypyrimidine tract binding protein 1

(Aliases: PTB-1,pPTB,AL033359,HNRPI,Ptb,AA407203,PTB4,PTB2,PTB3)

Ptbp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.052
regulation of membrane potential GO:0042391 192 0.051
cellular nitrogen compound catabolic process GO:0044270 280 0.043
aromatic compound catabolic process GO:0019439 286 0.043
heterocycle catabolic process GO:0046700 280 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
cellular amine metabolic process GO:0044106 44 0.037
ribose phosphate metabolic process GO:0019693 291 0.036
negative regulation of protein metabolic process GO:0051248 282 0.034
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
purine containing compound metabolic process GO:0072521 311 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
male gamete generation GO:0048232 285 0.031
Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.030
amine metabolic process GO:0009308 45 0.028
germ cell development GO:0007281 185 0.028
Fly
rna processing GO:0006396 105 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
regulation of organelle organization GO:0033043 289 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
carbohydrate metabolic process GO:0005975 230 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
Fly
dna metabolic process GO:0006259 303 0.025
macromolecule catabolic process GO:0009057 281 0.025
transmembrane transport GO:0055085 412 0.025
microtubule based process GO:0007017 236 0.025
Fly
cellular response to dna damage stimulus GO:0006974 207 0.024
Fly
muscle cell differentiation GO:0042692 261 0.024
Human
forebrain development GO:0030900 302 0.024
cation transport GO:0006812 399 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.022
immune effector process GO:0002252 321 0.022
translation GO:0006412 93 0.022
Fly
neural tube development GO:0021915 160 0.022
regulation of cell migration GO:0030334 219 0.022
chemotaxis GO:0006935 247 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
cellular macromolecule catabolic process GO:0044265 206 0.021
oxidation reduction process GO:0055114 342 0.021
nitrogen compound transport GO:0071705 271 0.021
nucleotide catabolic process GO:0009166 217 0.021
mitotic cell cycle GO:0000278 195 0.020
rna splicing GO:0008380 54 0.020
peptidyl amino acid modification GO:0018193 336 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
cellular homeostasis GO:0019725 240 0.020
Zebrafish
stem cell differentiation GO:0048863 268 0.020
ion transmembrane transport GO:0034220 361 0.020
organophosphate catabolic process GO:0046434 232 0.019
membrane organization GO:0061024 245 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
cellular chemical homeostasis GO:0055082 215 0.019
Zebrafish
carbohydrate derivative catabolic process GO:1901136 231 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
ossification GO:0001503 216 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
camera type eye development GO:0043010 266 0.019
nucleoside metabolic process GO:0009116 246 0.019
protein catabolic process GO:0030163 221 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
organelle assembly GO:0070925 177 0.019
cation homeostasis GO:0055080 212 0.019
Zebrafish
circulatory system process GO:0003013 197 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
cellular ketone metabolic process GO:0042180 84 0.018
nucleotide metabolic process GO:0009117 332 0.018
spermatogenesis GO:0007283 284 0.018
Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
blood vessel morphogenesis GO:0048514 285 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
regulation of cellular catabolic process GO:0031329 242 0.017
apoptotic signaling pathway GO:0097190 306 0.017
cytokine production GO:0001816 319 0.017
cellular response to lipid GO:0071396 145 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of neuron differentiation GO:0045664 281 0.017
response to acid chemical GO:0001101 111 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
endomembrane system organization GO:0010256 147 0.017
cation transmembrane transport GO:0098655 266 0.017
response to organonitrogen compound GO:0010243 246 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
Fly
glycosyl compound catabolic process GO:1901658 206 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
protein maturation GO:0051604 176 0.016
sensory perception GO:0007600 245 0.016
mitotic cell cycle process GO:1903047 159 0.016
myosin filament assembly GO:0031034 2 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
regulation of translation GO:0006417 71 0.016
Fly
cellular carbohydrate metabolic process GO:0044262 119 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
regulation of homeostatic process GO:0032844 182 0.016
wnt signaling pathway GO:0016055 188 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
Zebrafish
regulation of cell activation GO:0050865 289 0.016
Zebrafish
inorganic ion transmembrane transport GO:0098660 234 0.016
leukocyte differentiation GO:0002521 342 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of mapk cascade GO:0043408 248 0.015
action potential GO:0001508 78 0.015
tube formation GO:0035148 140 0.015
mapk cascade GO:0000165 281 0.015
digestive tract development GO:0048565 190 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
actin filament organization GO:0007015 113 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
dna repair GO:0006281 107 0.015
negative regulation of nervous system development GO:0051961 156 0.015
regulation of cytokine production GO:0001817 266 0.015
myosin filament organization GO:0031033 3 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
regulation of mrna metabolic process GO:1903311 43 0.015
innate immune response GO:0045087 157 0.015
inorganic cation transmembrane transport GO:0098662 207 0.014
regulation of anatomical structure size GO:0090066 178 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
mrna metabolic process GO:0016071 84 0.014
ras protein signal transduction GO:0007265 77 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
Zebrafish
ribonucleoside catabolic process GO:0042454 206 0.014
cell adhesion GO:0007155 329 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of inflammatory response GO:0050727 147 0.014
oocyte construction GO:0007308 2 0.014
Fly
developmental maturation GO:0021700 193 0.014
Fly
striated muscle myosin thick filament assembly GO:0071688 1 0.014
response to oxidative stress GO:0006979 123 0.014
lateral inhibition GO:0046331 1 0.014
axonogenesis GO:0007409 274 0.014
locomotory behavior GO:0007626 195 0.014
macromolecule methylation GO:0043414 120 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
maintenance of location GO:0051235 89 0.014
skeletal system morphogenesis GO:0048705 203 0.014
positive regulation of cell development GO:0010720 237 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of defense response GO:0031347 233 0.013
regulation of t cell proliferation GO:0042129 92 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
regulation of cellular component size GO:0032535 121 0.013
multicellular organism growth GO:0035264 161 0.013
single organism cell adhesion GO:0098602 156 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of response to wounding GO:1903034 189 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
actin cytoskeleton organization GO:0030036 220 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
homeostasis of number of cells GO:0048872 210 0.013
glucose homeostasis GO:0042593 128 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
nucleoside catabolic process GO:0009164 206 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
myeloid cell differentiation GO:0030099 233 0.012
inflammatory response GO:0006954 244 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
muscle system process GO:0003012 141 0.012
epithelial cell development GO:0002064 159 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
cellular ion homeostasis GO:0006873 165 0.012
Zebrafish
sensory organ morphogenesis GO:0090596 242 0.012
response to light stimulus GO:0009416 135 0.012
intracellular protein transport GO:0006886 204 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of cell adhesion GO:0030155 154 0.012
nuclear transport GO:0051169 139 0.012
metal ion homeostasis GO:0055065 189 0.012
Zebrafish
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
pole plasm assembly GO:0007315 2 0.012
cellular protein catabolic process GO:0044257 155 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
positive regulation of cell activation GO:0050867 158 0.012
Zebrafish
regulation of cell projection organization GO:0031344 206 0.012
cellular protein complex assembly GO:0043623 116 0.012
gland development GO:0048732 330 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
response to growth factor GO:0070848 198 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
Fly
skin development GO:0043588 220 0.011
stem cell development GO:0048864 219 0.011
compound eye development GO:0048749 1 0.011
response to extracellular stimulus GO:0009991 127 0.011
cell type specific apoptotic process GO:0097285 268 0.011
lipid biosynthetic process GO:0008610 179 0.011
cognition GO:0050890 149 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
fertilization GO:0009566 127 0.011
Zebrafish
regulation of rna splicing GO:0043484 37 0.011
purine containing compound catabolic process GO:0072523 213 0.011
peptide transport GO:0015833 133 0.011
adaptive immune response GO:0002250 155 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
regulation of secretion by cell GO:1903530 249 0.011
Zebrafish
regulation of transferase activity GO:0051338 263 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cell division GO:0051301 120 0.011
endocytosis GO:0006897 168 0.011
regulation of multi organism process GO:0043900 111 0.011
Zebrafish
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
positive regulation of cell death GO:0010942 224 0.011
nuclear division GO:0000280 158 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
dna endoreduplication GO:0042023 4 0.011
oocyte axis specification GO:0007309 2 0.011
Fly
regulation of hormone levels GO:0010817 211 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
muscle tissue development GO:0060537 308 0.011
t cell activation GO:0042110 289 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
glycosylation GO:0070085 62 0.011
positive regulation of protein modification process GO:0031401 299 0.011
anatomical structure homeostasis GO:0060249 145 0.011
Zebrafish
rna splicing via transesterification reactions GO:0000375 43 0.011
lymphocyte proliferation GO:0046651 164 0.011
regulation of proteolysis GO:0030162 164 0.011
rna interference GO:0016246 2 0.011
glucose metabolic process GO:0006006 92 0.011
organophosphate biosynthetic process GO:0090407 122 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
alcohol metabolic process GO:0006066 116 0.010
cell maturation GO:0048469 127 0.010
Fly
negative regulation of cell development GO:0010721 169 0.010
anion transport GO:0006820 177 0.010
glycoprotein metabolic process GO:0009100 116 0.010
response to radiation GO:0009314 165 0.010
protein ubiquitination GO:0016567 171 0.010
regulation of neuron projection development GO:0010975 169 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
multicellular organismal signaling GO:0035637 91 0.010
transmission of nerve impulse GO:0019226 76 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
leukocyte mediated immunity GO:0002443 174 0.010
protein localization to membrane GO:0072657 108 0.010
response to nutrient levels GO:0031667 109 0.010

Ptbp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.012
neurodegenerative disease DOID:1289 0 0.012